Published in Int J Cancer on December 20, 2005
The role of chalcones in suppression of NF-κB-mediated inflammation and cancer. Int Immunopharmacol (2010) 1.50
Concern Modification of the cysteine residues in IkappaBalpha kinase and NF-kappaB (p65) by xanthohumol leads to suppression of NF-kappaB-regulated gene products and potentiation of apoptosis in leukemia cells. Blood (2008) 1.42
Cancer cell signaling pathways targeted by spice-derived nutraceuticals. Nutr Cancer (2011) 1.07
Dietary chalcones with chemopreventive and chemotherapeutic potential. Genes Nutr (2011) 1.00
Growth inhibitory and apoptosis-inducing effects of xanthohumol, a prenylated chalone present in hops, in human prostate cancer cells. Anticancer Res (2010) 0.98
An update on antitumor activity of naturally occurring chalcones. Evid Based Complement Alternat Med (2013) 0.92
Xanthohumol suppresses oestrogen-signalling in breast cancer through the inhibition of BIG3-PHB2 interactions. Sci Rep (2014) 0.87
Inhibition of TGF-β signaling, vasculogenic mimicry and proinflammatory gene expression by isoxanthohumol. Invest New Drugs (2011) 0.85
Xanthohumol impairs human prostate cancer cell growth and invasion and diminishes the incidence and progression of advanced tumors in TRAMP mice. Mol Med (2012) 0.83
Immunomodulatory activity of xanthohumol: inhibition of T cell proliferation, cell-mediated cytotoxicity and Th1 cytokine production through suppression of NF-kappaB. Immunopharmacol Immunotoxicol (2009) 0.82
Xanthohumol inhibits Notch signaling and induces apoptosis in hepatocellular carcinoma. PLoS One (2015) 0.81
Xanthohumol-Mediated Suppression of Notch1 Signaling Is Associated with Antitumor Activity in Human Pancreatic Cancer Cells. Mol Cancer Ther (2015) 0.80
Xanthohumol induces growth inhibition and apoptosis in ca ski human cervical cancer cells. Evid Based Complement Alternat Med (2015) 0.79
Botanicals and Their Bioactive Phytochemicals for Women's Health. Pharmacol Rev (2016) 0.78
Anticancer agent xanthohumol inhibits IL-2 induced signaling pathways involved in T cell proliferation. J Exp Ther Oncol (2012) 0.78
DNA sequence and expression variation of hop (Humulus lupulus) valerophenone synthase (VPS), a key gene in bitter acid biosynthesis. Ann Bot (2008) 0.78
The involvement of xanthohumol in the expression of annexin in human malignant glioblastoma cells. Open Biochem J (2013) 0.75
Protein kinase A inhibition facilitates the antitumor activity of xanthohumol, a valosin-containing protein inhibitor. Cancer Sci (2017) 0.75
Stromal myofibroblasts are drivers of invasive cancer growth. Int J Cancer (2008) 4.30
Molecular signature and therapeutic perspective of the epithelial-to-mesenchymal transitions in epithelial cancers. Drug Resist Updat (2008) 2.59
Antitumor activity of the selective MDM2 antagonist nutlin-3 against chemoresistant neuroblastoma with wild-type p53. J Natl Cancer Inst (2009) 2.09
Shaping the breast in aesthetic and reconstructive breast surgery: an easy three-step principle. Part III--reconstruction following breast conservative treatment. Plast Reconstr Surg (2009) 2.09
Shaping the breast in aesthetic and reconstructive breast surgery: an easy three-step principle. Part IV--aesthetic breast surgery. Plast Reconstr Surg (2009) 2.08
Tenascin-C and SF/HGF produced by myofibroblasts in vitro provide convergent pro-invasive signals to human colon cancer cells through RhoA and Rac. FASEB J (2004) 2.01
Molecular and pathological signatures of epithelial-mesenchymal transitions at the cancer invasion front. Histochem Cell Biol (2008) 1.91
Withaferin a strongly elicits IkappaB kinase beta hyperphosphorylation concomitant with potent inhibition of its kinase activity. J Biol Chem (2006) 1.91
Effect of the secretory small GTPase Rab27B on breast cancer growth, invasion, and metastasis. J Natl Cancer Inst (2010) 1.65
The heregulin/human epidermal growth factor receptor as a new growth factor system in melanoma with multiple ways of deregulation. J Invest Dermatol (2003) 1.64
Shaping the breast in aesthetic and reconstructive breast surgery: an easy three-step principle. Part II--Breast reconstruction after total mastectomy. Plast Reconstr Surg (2009) 1.61
The impact of menopause on vocal quality. Menopause (2011) 1.47
The relation between body mass index and speaking fundamental frequency in premenopausal and postmenopausal women. Menopause (2011) 1.40
Microbial and dietary factors are associated with the equol producer phenotype in healthy postmenopausal women. J Nutr (2007) 1.38
Prenylated chalcone xanthohumol associates with histones in breast cancer cells--a novel target identified by a monoclonal antibody. Mol Nutr Food Res (2012) 1.38
TGF-beta signaling and collagen deposition in chronic rhinosinusitis. J Allergy Clin Immunol (2009) 1.36
The prenylflavonoid isoxanthohumol from hops (Humulus lupulus L.) is activated into the potent phytoestrogen 8-prenylnaringenin in vitro and in the human intestine. J Nutr (2006) 1.35
EGFR in melanoma: clinical significance and potential therapeutic target. J Cutan Pathol (2011) 1.32
An ex(o)citing machinery for invasive tumor growth. Cancer Res (2010) 1.31
Implication of metastasis suppressor NM23-H1 in maintaining adherens junctions and limiting the invasive potential of human cancer cells. Cancer Res (2010) 1.30
A first prospective, randomized, double-blind, placebo-controlled study on the use of a standardized hop extract to alleviate menopausal discomforts. Maturitas (2006) 1.29
Implication of STAT3 signaling in human colonic cancer cells during intestinal trefoil factor 3 (TFF3) -- and vascular endothelial growth factor-mediated cellular invasion and tumor growth. Cancer Res (2005) 1.27
Dual activities of galectin-3 in human prostate cancer: tumor suppression of nuclear galectin-3 vs tumor promotion of cytoplasmic galectin-3. Oncogene (2004) 1.26
Critical role of N-cadherin in myofibroblast invasion and migration in vitro stimulated by colon-cancer-cell-derived TGF-beta or wounding. J Cell Sci (2004) 1.24
Soluble cadherins as cancer biomarkers. Clin Exp Metastasis (2007) 1.20
Bone marrow-derived mesenchymal stem cells promote colorectal cancer progression through paracrine neuregulin 1/HER3 signalling. Gut (2012) 1.19
Role of WISP-2/CCN5 in the maintenance of a differentiated and noninvasive phenotype in human breast cancer cells. Mol Cell Biol (2007) 1.18
Modeling and quantification of cancer cell invasion through collagen type I matrices. Int J Dev Biol (2010) 1.17
Downregulation of gelsolin family proteins counteracts cancer cell invasion in vitro. Cancer Lett (2007) 1.11
Hop (Humulus lupulus)-derived bitter acids as multipotent bioactive compounds. J Nat Prod (2009) 1.10
Plasmin produces an E-cadherin fragment that stimulates cancer cell invasion. Biol Chem (2002) 1.09
Shaping the breast in aesthetic and reconstructive breast surgery: an easy three-step principle. Plast Reconstr Surg (2009) 1.08
Inhibition of cell survival, invasion, tumor growth and histone deacetylase activity by the dietary flavonoid luteolin in human epithelioid cancer cells. Eur J Pharmacol (2010) 1.08
P-cadherin is up-regulated by the antiestrogen ICI 182,780 and promotes invasion of human breast cancer cells. Cancer Res (2004) 1.05
The secretory small GTPase Rab27B as a marker for breast cancer progression. Oncotarget (2010) 1.01
Vacuolar H+ ATPase expression and activity is required for Rab27B-dependent invasive growth and metastasis of breast cancer. Int J Cancer (2013) 1.01
Metabolism of isoflavones, lignans and prenylflavonoids by intestinal bacteria: producer phenotyping and relation with intestinal community. FEMS Microbiol Ecol (2007) 1.01
The role of non-muscle myosin IIA in aggregation and invasion of human MCF-7 breast cancer cells. Int J Dev Biol (2011) 1.00
P-cadherin promotes cell-cell adhesion and counteracts invasion in human melanoma. Cancer Res (2005) 1.00
Microbial and dietary factors associated with the 8-prenylnaringenin producer phenotype: a dietary intervention trial with fifty healthy post-menopausal Caucasian women. Br J Nutr (2007) 0.99
Activation of proestrogens from hops (Humulus lupulus L.) by intestinal microbiota; conversion of isoxanthohumol into 8-prenylnaringenin. J Agric Food Chem (2005) 0.98
Xanthohumol kills B-chronic lymphocytic leukemia cells by an apoptotic mechanism. Mol Nutr Food Res (2005) 0.98
Roles for neuregulins in human cancer. Clin Exp Metastasis (2004) 0.98
DNA methylation-based biomarkers in serum of patients with breast cancer. Mutat Res (2012) 0.96
TRIP6, a novel molecular partner of the MAGI-1 scaffolding molecule, promotes invasiveness. FASEB J (2008) 0.96
Differential impact of TGF-beta and EGF on fibroblast differentiation and invasion reciprocally promotes colon cancer cell invasion. Cancer Lett (2008) 0.95
Disposition of hop prenylflavonoids in human breast tissue. Mol Nutr Food Res (2010) 0.94
Differential secretome analysis of cancer-associated fibroblasts and bone marrow-derived precursors to identify microenvironmental regulators of colon cancer progression. Proteomics (2013) 0.94
Resident and bone marrow-derived mesenchymal stem cells in head and neck squamous cell carcinoma. Oral Oncol (2010) 0.93
The tandem PDZ domains of syntenin promote cell invasion. Exp Cell Res (2007) 0.93
Estrogenic and anticarcinogenic properties of kurarinone, a lavandulyl flavanone from the roots of Sophora flavescens. J Nat Prod (2004) 0.93
Eubacterium limosum activates isoxanthohumol from hops (Humulus lupulus L.) into the potent phytoestrogen 8-prenylnaringenin in vitro and in rat intestine. J Nutr (2008) 0.92
The HMI™ module: a new tool to study the Host-Microbiota Interaction in the human gastrointestinal tract in vitro. BMC Microbiol (2014) 0.92
A safety study of oral tangeretin and xanthohumol administration to laboratory mice. In Vivo (2005) 0.92
Angiopoietin-like protein 4: health effects, modulating agents and structure-function relationships. Expert Rev Proteomics (2012) 0.92
Frondoside a suppressive effects on lung cancer survival, tumor growth, angiogenesis, invasion, and metastasis. PLoS One (2013) 0.92
Increased intrahepatic resistance in severe steatosis: endothelial dysfunction, vasoconstrictor overproduction and altered microvascular architecture. Lab Invest (2012) 0.91
P-cadherin in adhesion and invasion: opposite roles in colon and bladder carcinoma. Int J Cancer (2011) 0.90
Growth factor modulation of fibroblast proliferation, differentiation, and invasion: implications for tissue valve engineering. Tissue Eng (2006) 0.90
EMAS clinical guide: low-dose vaginal estrogens for postmenopausal vaginal atrophy. Maturitas (2012) 0.89
Forkhead box protein 3 in human nasal polyp regulatory T cells is regulated by the protein suppressor of cytokine signaling 3. J Allergy Clin Immunol (2013) 0.89
Melanoma cells secrete follistatin, an antagonist of activin-mediated growth inhibition. Oncogene (2004) 0.89
EMAS clinical guide: assessment of the endometrium in peri and postmenopausal women. Maturitas (2013) 0.88
Quantitation of soy-derived phytoestrogens in human breast tissue and biological fluids by high-performance liquid chromatography. J Chromatogr B Analyt Technol Biomed Life Sci (2003) 0.88
Subtle side-chain modifications of the hop phytoestrogen 8-prenylnaringenin result in distinct agonist/antagonist activity profiles for estrogen receptors alpha and beta. J Med Chem (2006) 0.88
Regioselective synthesis and estrogenicity of (+/-)-8-alkyl-5,7-dihydroxy-4-(4-hydroxyphenyl)-3,4-dihydrocoumarins. Eur J Med Chem (2005) 0.88
Bacterial monocultures, propionate, butyrate and H2O2 modulate the expression, secretion and structure of the fasting-induced adipose factor in gut epithelial cell lines. Environ Microbiol (2011) 0.88
Formation and accumulation of alpha-acids, beta-acids, desmethylxanthohumol, and xanthohumol during flowering of hops (Humulus lupulus L.). J Agric Food Chem (2003) 0.87
Alpha-catenin is required for IGF-I-induced cellular migration but not invasion in human colonic cancer cells. Oncogene (2004) 0.87
Soluble N-cadherin in human biological fluids. Int J Cancer (2006) 0.86
Xanthohumol activates the proapoptotic arm of the unfolded protein response in chronic lymphocytic leukemia. Anticancer Res (2009) 0.86
Diffusion tensor imaging provides an insight into the microstructure of meningiomas, high-grade gliomas, and peritumoral edema. J Comput Assist Tomogr (2012) 0.85
Tumor grafts derived from sarcoma patients retain tumor morphology, viability, and invasion potential and indicate disease outcomes in the chick chorioallantoic membrane model. Cancer Lett (2012) 0.85
The tumor ecosystem regulates the roads for invasion and metastasis. Clin Res Hepatol Gastroenterol (2011) 0.84
Selective modulation of the glucocorticoid receptor can distinguish between transrepression of NF-κB and AP-1. Cell Mol Life Sci (2013) 0.84
Compound A, a selective glucocorticoid receptor modulator, enhances heat shock protein Hsp70 gene promoter activation. PLoS One (2013) 0.84
Vocal characteristics of middle-aged premenopausal women. J Voice (2010) 0.84
The in ovo CAM-assay as a xenograft model for sarcoma. J Vis Exp (2013) 0.83
Cosupplementation of isoflavones, prenylflavonoids, and lignans alters human exposure to phytoestrogen-derived 17beta-estradiol equivalents. J Nutr (2009) 0.83
Disposition of soy isoflavones in normal human breast tissue. Am J Clin Nutr (2010) 0.83