A yeast by any other name: Candida glabrata and its interaction with the host.

PubWeight™: 1.76‹?› | Rank: Top 3%

🔗 View Article (PMID 15996895)

Published in Curr Opin Microbiol on August 01, 2005

Authors

Rupinder Kaur1, Renee Domergue, Margaret L Zupancic, Brendan P Cormack

Author Affiliations

1: Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, 617 Hunterian Building, 725 N. Wolfe St., Baltimore, MD 21205, USA.

Articles citing this

Discovering the secrets of the Candida albicans agglutinin-like sequence (ALS) gene family--a sticky pursuit. Med Mycol (2008) 2.46

A biochemical guide to yeast adhesins: glycoproteins for social and antisocial occasions. Microbiol Mol Biol Rev (2007) 2.00

Systematic phenotyping of a large-scale Candida glabrata deletion collection reveals novel antifungal tolerance genes. PLoS Pathog (2014) 1.98

A family of glycosylphosphatidylinositol-linked aspartyl proteases is required for virulence of Candida glabrata. Proc Natl Acad Sci U S A (2007) 1.93

Candida infections of the genitourinary tract. Clin Microbiol Rev (2010) 1.90

Secondary metabolism in fungi: does chromosomal location matter? Curr Opin Microbiol (2010) 1.46

Phylogenetic diversity of stress signalling pathways in fungi. BMC Evol Biol (2009) 1.40

Candida glabrata: a review of its features and resistance. Eur J Clin Microbiol Infect Dis (2013) 1.36

Two unlike cousins: Candida albicans and C. glabrata infection strategies. Cell Microbiol (2013) 1.19

Fungal sex and pathogenesis. Clin Microbiol Rev (2010) 1.16

High resistance to oxidative stress in the fungal pathogen Candida glabrata is mediated by a single catalase, Cta1p, and is controlled by the transcription factors Yap1p, Skn7p, Msn2p, and Msn4p. Eukaryot Cell (2008) 1.14

Contribution of CgPDR1-regulated genes in enhanced virulence of azole-resistant Candida glabrata. PLoS One (2011) 1.13

Candida glabrata environmental stress response involves Saccharomyces cerevisiae Msn2/4 orthologous transcription factors. Mol Microbiol (2008) 1.13

Autophagy supports Candida glabrata survival during phagocytosis. Cell Microbiol (2009) 1.11

Adhesins in human fungal pathogens: glue with plenty of stick. Eukaryot Cell (2013) 1.10

From Saccharomyces cerevisiae to Candida glabratain a few easy steps: important adaptations for an opportunistic pathogen. FEMS Microbiol Lett (2010) 1.08

Coevolution of morphology and virulence in Candida species. Eukaryot Cell (2011) 1.07

The potential impact of antifungal drug resistance mechanisms on the host immune response to Candida. Virulence (2012) 1.03

Role of an expanded inositol transporter repertoire in Cryptococcus neoformans sexual reproduction and virulence. MBio (2010) 1.01

A nonsense mutation in the ERG6 gene leads to reduced susceptibility to polyenes in a clinical isolate of Candida glabrata. Antimicrob Agents Chemother (2008) 1.00

Structural basis for promiscuity and specificity during Candida glabrata invasion of host epithelia. Proc Natl Acad Sci U S A (2012) 0.97

The high-osmolarity glycerol response pathway in the human fungal pathogen Candida glabrata strain ATCC 2001 lacks a signaling branch that operates in baker's yeast. Eukaryot Cell (2007) 0.97

Defining the transcriptomic landscape of Candida glabrata by RNA-Seq. Nucleic Acids Res (2015) 0.97

Functional genomic analysis of Candida glabrata-macrophage interaction: role of chromatin remodeling in virulence. PLoS Pathog (2012) 0.97

Expression of Candida glabrata adhesins after exposure to chemical preservatives. J Infect Dis (2009) 0.93

Heterogeneous expression of the virulence-related adhesin Epa1 between individual cells and strains of the pathogen Candida glabrata. Eukaryot Cell (2011) 0.92

Gain-of-function mutations in PDR1, a regulator of antifungal drug resistance in Candida glabrata, control adherence to host cells. Infect Immun (2013) 0.92

Reinventing heterochromatin in budding yeasts: Sir2 and the origin recognition complex take center stage. Eukaryot Cell (2011) 0.91

Prion-forming ability of Ure2 of yeasts is not evolutionarily conserved. Genetics (2011) 0.88

Transfer of genetic material between pathogenic and food-borne yeasts. Appl Environ Microbiol (2006) 0.87

Regulation of Candida glabrata oxidative stress resistance is adapted to host environment. FEBS Lett (2010) 0.87

Candida glabrata Binding to Candida albicans Hyphae Enables Its Development in Oropharyngeal Candidiasis. PLoS Pathog (2016) 0.86

Metabolism in fungal pathogenesis. Cold Spring Harb Perspect Med (2014) 0.86

Immune evasion, stress resistance, and efficient nutrient acquisition are crucial for intracellular survival of Candida glabrata within macrophages. Eukaryot Cell (2013) 0.85

ER stress response mechanisms in the pathogenic yeast Candida glabrata and their roles in virulence. Virulence (2013) 0.85

Functional characterization of the CgPGS1 gene reveals a link between mitochondrial phospholipid homeostasis and drug resistance in Candida glabrata. Curr Genet (2008) 0.85

Candida glabrata Pwp7p and Aed1p are required for adherence to human endothelial cells. FEMS Yeast Res (2011) 0.84

Mutants in the Candida glabrata glycerol channels are sensitized to cell wall stress. Eukaryot Cell (2012) 0.84

A novel downstream regulatory element cooperates with the silencing machinery to repress EPA1 expression in Candida glabrata. Genetics (2012) 0.84

The inositol regulon controls viability in Candida glabrata. Microbiology (2009) 0.84

G-quadruplexes in pathogens: a common route to virulence control? PLoS Pathog (2015) 0.83

The Rho1 GTPase-activating protein CgBem2 is required for survival of azole stress in Candida glabrata. J Biol Chem (2011) 0.82

Structural Hot Spots Determine Functional Diversity of the Candida glabrata Epithelial Adhesin Family. J Biol Chem (2015) 0.82

Small chromosomes among Danish Candida glabrata isolates originated through different mechanisms. Antonie Van Leeuwenhoek (2013) 0.81

A Candida-based view of fungal sex and pathogenesis. Genome Biol (2009) 0.80

Candida albicans repetitive elements display epigenetic diversity and plasticity. Sci Rep (2016) 0.80

CgCYN1, a plasma membrane cystine-specific transporter of Candida glabrata with orthologues prevalent among pathogenic yeast and fungi. J Biol Chem (2011) 0.80

Genome structure and dynamics of the yeast pathogen Candida glabrata. FEMS Yeast Res (2014) 0.80

Genome engineering in the yeast pathogen Candida glabrata using the CRISPR-Cas9 system. Sci Rep (2016) 0.80

β-glucan induces reactive oxygen species production in human neutrophils to improve the killing of Candida albicans and Candida glabrata isolates from vulvovaginal candidiasis. PLoS One (2014) 0.79

Conserved WCPL and CX4C domains mediate several mating adhesin interactions in Saccharomyces cerevisiae. Genetics (2009) 0.79

Mitochondrial DNA heteroplasmy in Candida glabrata after mitochondrial transformation. Eukaryot Cell (2010) 0.78

Establishment of an in vitro system to study intracellular behavior of Candida glabrata in human THP-1 macrophages. J Vis Exp (2013) 0.78

Telomere components as potential therapeutic targets for treating microbial pathogen infections. Front Oncol (2012) 0.77

A Novel Hybrid Iron Regulation Network Combines Features from Pathogenic and Nonpathogenic Yeasts. MBio (2016) 0.77

Iron-depletion promotes mitophagy to maintain mitochondrial integrity in pathogenic yeast Candida glabrata. Autophagy (2016) 0.77

The Phosphoinositide 3-Kinase Regulates Retrograde Trafficking of the Iron Permease CgFtr1 and Iron Homeostasis in Candida glabrata. J Biol Chem (2016) 0.76

Pivotal role for a tail subunit of the RNA polymerase II mediator complex CgMed2 in azole tolerance and adherence in Candida glabrata. Antimicrob Agents Chemother (2014) 0.76

The Chromatin of Candida albicans Pericentromeres Bears Features of Both Euchromatin and Heterochromatin. Front Microbiol (2016) 0.76

Generational distribution of a Candida glabrata population: Resilient old cells prevail, while younger cells dominate in the vulnerable host. PLoS Pathog (2017) 0.76

Partial Decay of Thiamine Signal Transduction Pathway Alters Growth Properties of Candida glabrata. PLoS One (2016) 0.75

Identification of Genes in Candida glabrata Conferring Altered Responses to Caspofungin, a Cell Wall Synthesis Inhibitor. G3 (Bethesda) (2016) 0.75

Determination of MICING: a new assay for assessing minimal inhibitory concentration for invasive growth. Eur J Clin Microbiol Infect Dis (2015) 0.75

The EPA2 adhesin encoding gene is responsive to oxidative stress in the opportunistic fungal pathogen Candida glabrata. Curr Genet (2015) 0.75

Functional analysis of selected deletion mutants in Candida glabrata under hypoxia. 3 Biotech (2017) 0.75

The Effectiveness of Voriconazole in Therapy of Candida glabrata's Biofilms Oral Infections and Its Influence on the Matrix Composition and Gene Expression. Mycopathologia (2017) 0.75

Articles by these authors

A nuclear receptor-like pathway regulating multidrug resistance in fungi. Nature (2008) 3.00

Nicotinic acid limitation regulates silencing of Candida adhesins during UTI. Science (2005) 2.03

Glycan microarray analysis of Candida glabrata adhesin ligand specificity. Mol Microbiol (2008) 1.96

Virulence-related surface glycoproteins in the yeast pathogen Candida glabrata are encoded in subtelomeric clusters and subject to RAP1- and SIR-dependent transcriptional silencing. Genes Dev (2003) 1.94

A family of glycosylphosphatidylinositol-linked aspartyl proteases is required for virulence of Candida glabrata. Proc Natl Acad Sci U S A (2007) 1.93

Modular domain structure in the Candida glabrata adhesin Epa1p, a beta1,6 glucan-cross-linked cell wall protein. Mol Microbiol (2002) 1.65

Telomere length control and transcriptional regulation of subtelomeric adhesins in Candida glabrata. Mol Microbiol (2005) 1.56

Functional genomic analysis of fluconazole susceptibility in the pathogenic yeast Candida glabrata: roles of calcium signaling and mitochondria. Antimicrob Agents Chemother (2004) 1.46

Tn7-based genome-wide random insertional mutagenesis of Candida glabrata. Genome Res (2003) 1.36

The omega-site sequence of glycosylphosphatidylinositol-anchored proteins in Saccharomyces cerevisiae can determine distribution between the membrane and the cell wall. Mol Microbiol (2003) 1.19

Insertion site preference of Mu, Tn5, and Tn7 transposons. Mob DNA (2012) 1.17

Multiple sequence signals determine the distribution of glycosylphosphatidylinositol proteins between the plasma membrane and cell wall in Saccharomyces cerevisiae. Microbiology (2004) 1.05

Overcoming functional redundancy to elicit pachyonychia congenita-like nail lesions in transgenic mice. Mol Cell Biol (2005) 0.99

Assimilation of NAD(+) precursors in Candida glabrata. Mol Microbiol (2007) 0.99

Candida albicans SOD5 represents the prototype of an unprecedented class of Cu-only superoxide dismutases required for pathogen defense. Proc Natl Acad Sci U S A (2014) 0.93

yKu70/yKu80 and Rif1 regulate silencing differentially at telomeres in Candida glabrata. Eukaryot Cell (2008) 0.92

High-affinity transporters for NAD+ precursors in Candida glabrata are regulated by Hst1 and induced in response to niacin limitation. Mol Cell Biol (2009) 0.87

Retrotransposon overdose and genome integrity. Proc Natl Acad Sci U S A (2009) 0.84

Mutants in the Candida glabrata glycerol channels are sensitized to cell wall stress. Eukaryot Cell (2012) 0.84

Expression plasmids for use in Candida glabrata. G3 (Bethesda) (2013) 0.84

The uses of green fluorescent protein in prokaryotes. Methods Biochem Anal (2006) 0.81

Investigation of the function of Candida albicans Als3 by heterologous expression in Candida glabrata. Infect Immun (2013) 0.79