Published in Eur J Immunol on June 01, 1992
B lymphocytes may escape tolerance by revising their antigen receptors. J Exp Med (1993) 2.78
Passenger transgenes reveal intrinsic specificity of the antibody hypermutation mechanism: clustering, polarity, and specific hot spots. Proc Natl Acad Sci U S A (1993) 2.30
Altered spectra of hypermutation in antibodies from mice deficient for the DNA mismatch repair protein PMS2. Proc Natl Acad Sci U S A (1998) 1.86
P nucleotides in V(D)J recombination: a fine-structure analysis. Mol Cell Biol (1993) 1.64
Conservation of sequence in recombination signal sequence spacers. Nucleic Acids Res (1994) 1.58
Analysis of somatic hypermutation in mouse Peyer's patches using immunoglobulin kappa light-chain transgenes. Proc Natl Acad Sci U S A (1993) 1.46
The structural repertoire of the human V kappa domain. EMBO J (1995) 1.26
Breakdown of B cell tolerance in a mouse model of systemic lupus erythematosus. J Exp Med (1995) 1.18
Analysis of patterns of DNA sequence variation in flanking and coding regions of murine germ-line immunoglobulin heavy-chain variable genes: evolutionary implications. Proc Natl Acad Sci U S A (1994) 1.02
Skewed primary Igκ repertoire and V-J joining in C57BL/6 mice: implications for recombination accessibility and receptor editing. J Immunol (2012) 0.98
Restricted kappa chain expression in early ontogeny: biased utilization of V kappa exons and preferential V kappa-J kappa recombinations. J Exp Med (1993) 0.78
Violations of the 12/23 rule at the mouse immunoglobulin kappa locus, including V kappa-V kappa rearrangement. Mol Immunol (2009) 0.77
A direct estimate of the human alphabeta T cell receptor diversity. Science (1999) 6.85
Scatter factor is a fibroblast-derived modulator of epithelial cell mobility. Nature (1987) 6.26
Scatter factor/hepatocyte growth factor is essential for liver development. Nature (1995) 5.91
T-cell repertoire diversity and clonal expansions in normal and clinical samples. Immunol Today (1995) 3.60
An approach to random mutagenesis of DNA using mixtures of triphosphate derivatives of nucleoside analogues. J Mol Biol (1996) 3.15
Developmental roles of HGF/SF and its receptor, the c-Met tyrosine kinase. Trends Cell Biol (1998) 3.05
Update of Clostridium difficile infection due to PCR ribotype 027 in Europe, 2008. Euro Surveill (2008) 2.43
Sequence analysis of immunoglobulin light chain messenger RNA. Nature (1974) 2.22
Oligoclonality of tumor-infiltrating lymphocytes from human melanomas. J Immunol (1994) 2.21
Two classes of CD1 genes. Eur J Immunol (1989) 2.11
Structural repertoire of the human VH segments. J Mol Biol (1992) 2.06
The effect of high-frequency random mutagenesis on in vitro protein evolution: a study on TEM-1 beta-lactamase. J Mol Biol (1999) 2.00
Original and artificial antibodies. Nature (1992) 1.97
onc sequences (v-fes) of Snyder-Theilen feline sarcoma virus are derived from noncontiguous regions of a cat cellular gene (c-fes). Nature (1981) 1.95
Expanded CD4+ and CD8+ T cell clones in elderly humans. J Immunol (1997) 1.84
Somatic hypermutation of immunoglobulin kappa may depend on sequences 3' of C kappa and occurs on passenger transgenes. EMBO J (1991) 1.83
T cell response to Epstein-Barr virus transactivators in chronic rheumatoid arthritis. J Exp Med (1996) 1.80
Roles of hepatocyte growth factor/scatter factor and the met receptor in the early development of the metanephros. J Cell Biol (1995) 1.79
Hepatocytes and scatter factor. Nature (1990) 1.77
Affinity maturation leads to differential expression of multiple copies of a kappa light-chain transgene. Nature (1993) 1.75
Nucleotide sequences of feline sarcoma virus long terminal repeats and 5' leaders show extensive homology to those of other mammalian retroviruses. J Virol (1983) 1.71
Heparan sulfate-modified CD44 promotes hepatocyte growth factor/scatter factor-induced signal transduction through the receptor tyrosine kinase c-Met. J Biol Chem (1999) 1.58
Activation of memory and virgin B cell clones in hyperimmune animals. Eur J Immunol (1987) 1.54
Regulation of cell movement: the motogenic cytokines. Biochim Biophys Acta (1991) 1.53
The umbilical cord blood alphabeta T-cell repertoire: characteristics of a polyclonal and naive but completely formed repertoire. Blood (1998) 1.48
Purification and sequence of messenger RNA for immunoglobulin light chains. Nat New Biol (1973) 1.46
Mutant feline sarcoma proviruses containing the viral oncogene (v-fes) and either feline or murine control elements. J Virol (1983) 1.38
Mutation and selection during the secondary response to 2-phenyloxazolone. Proc Natl Acad Sci U S A (1991) 1.35
Recombinant bacteriophages containing the integrated transforming provirus of Gardner--Arnstein feline sarcoma virus. Proc Natl Acad Sci U S A (1981) 1.31
C-terminal half of immunoglobulin lambda-chains. Nature (1967) 1.30
Molecular evolution and domain structure of plasminogen-related growth factors (HGF/SF and HGF1/MSP). Protein Sci (1994) 1.29
Epithelial scatter factor and development of the chick embryonic axis. Development (1990) 1.28
Crystal structures of NK1-heparin complexes reveal the basis for NK1 activity and enable engineering of potent agonists of the MET receptor. EMBO J (2001) 1.28
The 5' boundary of somatic hypermutation in a V kappa gene is in the leader intron. Eur J Immunol (1994) 1.27
The structural repertoire of the human V kappa domain. EMBO J (1995) 1.26
Involvement of hepatocyte growth factor/scatter factor and met receptor signaling in hair follicle morphogenesis and cycling. FASEB J (2000) 1.26
A role for HGF/SF in neural induction and its expression in Hensen's node during gastrulation. Development (1995) 1.25
Light chain germ-line genes and the immune response to 2-phenyloxazolone. EMBO J (1985) 1.24
Diversity of human alpha beta T cell receptors. Science (2000) 1.24
Crystal structure of the NK1 fragment of HGF/SF suggests a novel mode for growth factor dimerization and receptor binding. Nat Struct Biol (1999) 1.14
Insights into the structure/function of hepatocyte growth factor/scatter factor from studies with individual domains. J Mol Biol (2007) 1.12
Engineered mutants of HGF/SF with reduced binding to heparan sulphate proteoglycans, decreased clearance and enhanced activity in vivo. Curr Biol (1998) 1.10
Immunoglobulin lambda-chains. The complete amino acid sequence of a Bence-Jones protein. Biochem J (1968) 1.09
Co-expression of the HGF/SF and c-met genes during early mouse embryogenesis precedes reciprocal expression in adjacent tissues during organogenesis. Dev Genet (1996) 1.07
Patients' perception of public, voluntary and private dispensaries in rural areas of Tanzania. East Afr Med J (1996) 1.04
Demonstration that a mouse immunoglobulin light chain messenger RNA hybridizes exclusively with unique DNA. Cell (1975) 0.99
Idiotype vaccination in human myeloma: generation of tumor-specific immune responses after high-dose chemotherapy. Blood (1999) 0.99
Characterization of the scatter factor/hepatocyte growth factor gene promoter. Positive and negative regulatory elements direct gene expression to mesenchymal cells. J Biol Chem (1995) 0.96
Selection of T cells reactive against autologous B lymphoblastoid cells during chronic rheumatoid arthritis. J Immunol (1996) 0.95
Recombinant soluble receptors for the Fc gamma portion inhibit antibody production in vitro. Eur J Immunol (1989) 0.95
The infection of human dendritic cells with recombinant avipox vectors expressing a costimulatory molecule transgene (CD80) to enhance the activation of antigen-specific cytolytic T cells. Cancer Res (2001) 0.95
Evidence for T-cell clonal expansion in a patient with squamous cell carcinoma of the head and neck. Cancer Res (1994) 0.94
Structure of the mouse beta Fc gamma receptor II gene. J Immunol (1991) 0.94
Tumor-specific immune response: current in vitro analyses may not reflect the in vivo immune status. Crit Rev Immunol (1998) 0.93
Soluble Fc gamma receptors II (Fc gamma RII) are generated by cleavage of membrane Fc gamma RII. Eur J Immunol (1991) 0.92
Expression of HGF/SF, HGF1/MSP, and c-met suggests new functions during early chick development. Dev Genet (1995) 0.92
In vivo T-cell clonal amplification at time of acute graft-versus-host disease. Blood (1994) 0.90
Factors affecting epithelial interactions. Ciba Found Symp (1987) 0.90
Cutaneous periarteritis nodosa. Hepatitis B surface antigen-containing immunocomplexes and polymorphonuclear-leukocyte lysosomal enzyme release. Arch Dermatol (1984) 0.89
Acute graft versus host disease due to T lymphocytes recognizing a single HLA-DPB1*0501 mismatch. J Clin Invest (1996) 0.89
Scatter factor and other regulators of cell mobility. Br Med Bull (1989) 0.87
Colony assays for antibody fragments expressed in bacteria. J Immunol Methods (1991) 0.87
Evaluating the visual field effects of blepharoptosis using automated static perimetry. Ophthalmology (1993) 0.87
Signalling by HGF/SF and Met: the role of heparan sulphate co-receptors. Biochem Soc Trans (2006) 0.87
Involvement of soluble CD95 in Churg-Strauss syndrome. Am J Pathol (1999) 0.86
CD95 ligand expression as a mechanism of immune escape in breast cancer. Immunology (2000) 0.86
Restriction of the T-cell repertoire in tumor-infiltrating lymphocytes from nine patients with renal-cell carcinoma. Relevance of the CDR3 length analysis for the identification of in situ clonal T-cell expansions. Int J Cancer (1996) 0.86
Occurrence of the Inv genetic markers in the subgroups of human kappa chains. J Mol Biol (1969) 0.86
Universal cloning and direct sequencing of rearranged antibody V genes using C region primers, biotin-captured cDNA and one-side PCR. J Immunol Methods (1995) 0.85
Identical T-cell receptor beta chain rearrangements are present in T cells infiltrating the jejunal mucosa of untreated celiac patients. Hum Immunol (1997) 0.84
Spread of clonal T-cell expansions in rheumatoid arthritis patients. Hum Immunol (1997) 0.84
CD95 ligand expression in dedifferentiated breast cancer. J Pathol (1999) 0.83
Regulation of CD95 (Apo-1/Fas) ligand and receptor expression in squamous-cell carcinoma by interferon-gamma and cisplatin. Int J Cancer (1999) 0.83
Genetic diversity of noroviruses from outbreaks, sporadic cases and wastewater in Luxembourg 2008-2009. Clin Microbiol Infect (2011) 0.83
The murine Fc-gamma (Fc gamma) receptor type II B1 is a tumorigenicity-enhancing factor in polyoma-virus-transformed 3T3 cells. Int J Cancer (1996) 0.83
Expression of a Cx43 deletion mutant in 3T3 A31 fibroblasts prevents PDGF-induced inhibition of cell communication and suppresses cell growth. Exp Cell Res (1999) 0.83
Murine type II Fc gamma receptors and IgG-binding factors. Chem Immunol (1989) 0.82
A reporter gene to analyse the hypermutation of immunoglobulin genes. J Mol Biol (1995) 0.82
Severe and long-lasting disruption of T-cell receptor diversity in human myeloma after high-dose chemotherapy and autologous peripheral blood progenitor cell infusion. Br J Haematol (2001) 0.82
Methylation in the 5' region of the murine beta Fc gamma R gene regulates the expression of Fc gamma receptor II. J Immunol (1988) 0.82
V genes of the primary antibody response of C57BL/10 mice to the hapten phenyloxazolone. Eur J Immunol (1988) 0.82
Preliminary crystallographic study of the Fab fragments of two monoclonal anti-2-phenyloxazolone antibodies. J Biol Chem (1985) 0.82
Molecular events during the onset and maturation of the antibody response. Biochem Soc Symp (1986) 0.82
HGF/SF inhibits junctional communication. Exp Cell Res (1995) 0.81
Clonality of tumor-infiltrating lymphocytes in human urinary bladder carcinoma. J Immunother (1997) 0.81
Prevalence, risk factors and molecular epidemiology of methicillin-resistant Staphylococcus aureus (MRSA) colonization in residents of long-term care facilities in Luxembourg, 2010. Epidemiol Infect (2012) 0.81
Deranged CD95 system in a case of Churg-Strauss vasculitis. Gastroenterology (1998) 0.81
Molecular and functional studies of recombinant soluble Fc gamma receptors. Mol Immunol (1990) 0.81
Mumps outbreak among the military in Luxembourg in 2008: epidemiology and evaluation of control measures. Euro Surveill (2009) 0.81
Two adjacent mutations at position 12 activate the K-ras2 oncogene of a human mammary tumor cell line. Oncogene Res (1987) 0.80
Topography of apolipoprotein B in subcellular fractions of rabbit liver probed with a panel of monoclonal antibodies. J Lipid Res (1993) 0.80
In vivo acquisition of Fc gamma RII expression on polyoma virus-transformed cells derived from tumors of long latency. Cancer Res (1991) 0.80
Insights into the structure of hepatocyte growth factor/scatter factor (HGF/SF) and implications for receptor activation. FEBS Lett (1998) 0.80
Determination of the intracellular distribution and pool sizes of apolipoprotein B in rabbit liver. Biochem J (1992) 0.80
Relationship among the concentrations of serum lipoproteins and changes in their chemical composition in patients with untreated nephrotic syndrome. Eur J Clin Invest (1977) 0.79
T-cell repertoire analysis in chronic plaque psoriasis suggests an antigen-specific immune response. Hum Immunol (1999) 0.79
Chemical and morphological changes of rat plasma lipoproteins after a prolonged administration of diets containing olive oil and cholesterol. Atherosclerosis (1977) 0.79
Substantial reduction of human Salmonella Enteritidis infections in Luxembourg in 2005. Euro Surveill (2006) 0.79