M Gottesman

Author PubWeight™ 89.09‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Control of transcription termination. Annu Rev Biochem 1978 9.24
2 Promoter occlusion: transcription through a promoter may inhibit its activity. Cell 1982 4.43
3 Lac DNA, RNA polymerase and cyclic AMP receptor protein, cyclic AMP, lac repressor and inducer are the essential elements for controlled lac transcription. Nat New Biol 1971 3.79
4 Protein degradation in E. coli: the lon mutation and bacteriophage lambda N and cII protein stability. Cell 1981 3.58
5 Regulation of lac mRNA synthesis in a soluble cell-free system. Nat New Biol 1971 3.25
6 Release of polarity in Escherichia coli by gene N of phage lambda: termination and antitermination of transcription. Proc Natl Acad Sci U S A 1974 2.92
7 Multiple-drug resistance in human cancer. N Engl J Med 1987 2.76
8 Effect of Rho on transcription of bacterial operons. Nat New Biol 1973 2.74
9 Mre11 protein complex prevents double-strand break accumulation during chromosomal DNA replication. Mol Cell 2001 2.65
10 Activation of transcription at specific promoters by glycerol. J Biol Chem 1974 1.95
11 Reconstitution of an ATM-dependent checkpoint that inhibits chromosomal DNA replication following DNA damage. Mol Cell 2000 1.75
12 Hyperdegradation of proteins in Escherichia coli rho mutants. Proc Natl Acad Sci U S A 1979 1.65
13 Retroregulation: control of gene expression from sites distal to the gene. Cell 1982 1.65
14 Integration host factor stimulates the phage lambda pL promoter. J Mol Biol 1990 1.61
15 Regulation of bacteriophage lambda int gene expression. J Mol Biol 1982 1.52
16 Translation initiation of bacteriophage lambda gene cII requires integration host factor. J Bacteriol 1986 1.51
17 Selection of drug-resistant bone marrow cells in vivo after retroviral transfer of human MDR1. Science 1992 1.49
18 Specificity of the bacteriophage lambda N gene product (pN): nut sequences are necessary and sufficient for antitermination by pN. Cell 1979 1.47
19 Isolation of the gal repressor. Proc Natl Acad Sci U S A 1971 1.47
20 Attachment site mutants of bacteriophage lambda. J Mol Biol 1973 1.39
21 Effects of dimethylsulfoxide on the E. coli gal operon and on bacteriophage lambda in vivo. Cell 1974 1.39
22 Regulation of galactokinase synthesis by cyclic adenosine 3',5'-monophosphate in cell-free extracts of Escherichia coli. J Biol Chem 1971 1.38
23 HU and integration host factor function as auxiliary proteins in cleavage of phage lambda cohesive ends by terminase. J Bacteriol 1991 1.37
24 Control of bacteriophage lambda CII activity by bacteriophage and host functions. J Bacteriol 1984 1.30
25 Excision of prophage lambda in a cell-free system. Proc Natl Acad Sci U S A 1975 1.28
26 Studies on the mechanism of action of the gal repressor. J Biol Chem 1973 1.22
27 Regulation of the pR operon of bacteriophage lambda. J Mol Appl Genet 1983 1.17
28 Suppression of polarity of insertion mutations in the gal operon and N mutations in bacteriophage lambda. J Bacteriol 1976 1.17
29 Formation of lambda lysogens by IS2 recombination: gal operon--lambda pR promoter fusions. Virology 1979 1.15
30 Rapid disease course in African Americans with multiple sclerosis. Neurology 2010 1.10
31 Biochemical basis for depressed serum retinol levels in transthyretin-deficient mice. J Biol Chem 2001 1.05
32 Transfer and expression of the human multiple drug resistance gene into live mice. Proc Natl Acad Sci U S A 1992 1.01
33 Selective effects of MgCl2 and temperature on the initiation of transcription at lac, gal, and lambda promoters. J Biol Chem 1975 1.00
34 Promoter resurrection by activators--a minireview. Gene 1993 0.96
35 Symptomatic scapholunatotriquetral carpal coalition with fusion of the capitatometacarpal joint. Report of a case. Clin Orthop Relat Res 1990 0.94
36 Bacteriophage lambda hin function. II. Enhanced stability of lambda messenger RNA. J Mol Biol 1980 0.93
37 Bacteriophage lambda hin function. I. Pleiotropic alteration in host physiology. J Mol Biol 1980 0.93
38 Thyroid hormone distribution in the mouse brain: the role of transthyretin. Neuroscience 2002 0.93
39 A mutation affecting the catalytic subunit of cyclic AMP-dependent protein kinase in CHO cells. J Biol Chem 1979 0.92
40 Description and properties of bacteriophage lambda vectors useful for the cloning of EcoRI DNA fragments. Biochimie 1978 0.92
41 Stimulation of IS1 excision by bacteriophage P1 ref function. J Bacteriol 1989 0.89
42 Leptospirosis in febrile men ingesting Agouti paca in South America. Ann Trop Med Parasitol 2004 0.89
43 Isolation of Escherichia coli rpoB mutants resistant to killing by lambda cII protein and altered in pyrE gene attenuation. J Bacteriol 1987 0.87
44 A randomized control trial of an Ultra-Short zidovudine regimen in the prevention of perinatal HIV transmission in rural Zimbabwe. Cent Afr J Med 2006 0.86
45 Transthyretin regulates thyroid hormone levels in the choroid plexus, but not in the brain parenchyma: study in a transthyretin-null mouse model. Endocrinology 2000 0.86
46 P-glycoprotein-mediated multidrug resistance in normal and neoplastic hematopoietic cells. Ann Hematol 1994 0.85
47 The activity of Salmonella phage P22 gene 24 product in Escherichia coli. Virology 1978 0.83
48 Independence of gene N and tof functions of bacteriophage lambda. J Mol Biol 1977 0.81
49 Molecular manipulations of the multidrug transporter: a new role for transgenic mice. FASEB J 1991 0.81
50 Disco-ordinate expression of the Escherichia coli gal operon after prophage lambda induction. J Mol Biol 1978 0.81
51 E. coli mutants produced by the insertion of bacteriophage lambda DNA. Genetics 1973 0.80
52 Using mutants to study cAMP-dependent protein kinase. Methods Enzymol 1983 0.79
53 Regulation of single and multicopy his operons in Escherichia coli. J Bacteriol 1985 0.79
54 Kinetic properties of cobalt alkaline phosphatase. Biochemistry 1969 0.79
55 Retraction: renaturation of denatured lambda repressor requires heat shock proteins. Cell 1992 0.78
56 Termination and antitermination in transcription: control of gene expression. Basic Life Sci 1974 0.77
57 Are tissues a patch quilt of ectopic gene expression? Science 1989 0.77
58 Decreased transthyretin (TTR) concentrations in the cerebrospinal fluid after lead exposure. Toxicol Appl Pharmacol 1997 0.75
59 Transfer and expression of the human multidrug resistance gene in mouse erythroleukemia cells. Blood 1992 0.75
60 Helsinki final act. Science 1980 0.75
61 DNA-mediated transfer of cAMP resistance in CHO cells. J Cell Physiol 1986 0.75
62 Neurology, age, hospital costs, and DRGs. Neurology 1988 0.75
63 Conservation development in blind children. Child Dev 1973 0.75
64 The new refuseniks. Science 1984 0.75
65 A comparative study of Piaget's developmental schema of sighted children with that of a group of blind children. Child Dev 1971 0.75