Abnormal basement membrane in the inner ear and the kidney of the Mpv17-/- mouse strain: ultrastructural and immunohistochemical investigations.

PubWeight™: 0.90‹?›

🔗 View Article (PMID 16041630)

Published in Histochem Cell Biol on July 26, 2005

Authors

Angela M Meyer zum Gottesberge1, Heidi Felix

Author Affiliations

1: Research Laboratory, Department of Otorhinolaryngology, University of Düsseldorf, Moorenstr, 5, 40225, Dusseldorf, Germany, mzg@uni-duesseldorf.de.

Articles cited by this

Laminin functions in tissue morphogenesis. Annu Rev Cell Dev Biol (2004) 4.22

Molecular architecture of basement membranes. FASEB J (1990) 3.28

Autoimmune sensorineural hearing loss. Ann Otol Rhinol Laryngol (1979) 2.90

Extracellular matrix metabolism in diabetic nephropathy. J Am Soc Nephrol (2003) 2.85

A new nomenclature for the laminins. Matrix Biol (1994) 2.82

Collagen COL4A3 knockout: a mouse model for autosomal Alport syndrome. Genes Dev (1996) 2.58

The renal glomerulus of mice lacking s-laminin/laminin beta 2: nephrosis despite molecular compensation by laminin beta 1. Nat Genet (1995) 2.30

Molecular and functional defects in kidneys of mice lacking collagen alpha 3(IV): implications for Alport syndrome. J Cell Biol (1996) 2.29

Preemptive ramipril therapy delays renal failure and reduces renal fibrosis in COL4A3-knockout mice with Alport syndrome. Kidney Int (2003) 2.20

Integrin alpha1beta1 and transforming growth factor-beta1 play distinct roles in alport glomerular pathogenesis and serve as dual targets for metabolic therapy. Am J Pathol (2000) 1.90

Laminin-1 reexpression in Alport mouse glomerular basement membranes. Kidney Int (2003) 1.88

Alport syndrome. An inherited disorder of renal, ocular, and cochlear basement membranes. Medicine (Baltimore) (1999) 1.76

Transgenic mouse model of kidney disease: insertional inactivation of ubiquitously expressed gene leads to nephrotic syndrome. Cell (1990) 1.71

The laminins. Matrix Biol (1994) 1.67

Ear and kidney syndromes: molecular versus clinical approach. Kidney Int (2004) 1.59

Still more complexity in mammalian basement membranes. J Histochem Cytochem (2000) 1.57

Laminins: structure and genetic regulation. Microsc Res Tech (2000) 1.38

Glomerular overproduction of oxygen radicals in Mpv17 gene-inactivated mice causes podocyte foot process flattening and proteinuria: A model of steroid-resistant nephrosis sensitive to radical scavenger therapy. Am J Pathol (1999) 1.25

Role for transforming growth factor-beta1 in alport renal disease progression. Kidney Int (1999) 1.22

Abnormal glomerular basement membrane laminins in murine, canine, and human Alport syndrome: aberrant laminin alpha2 deposition is species independent. J Am Soc Nephrol (2001) 1.20

The glomerulosclerosis gene Mpv17 encodes a peroxisomal protein producing reactive oxygen species. EMBO J (1994) 1.18

Alterations in microvasculature are associated with atrophy of the stria vascularis in quiet-aged gerbils. Hear Res (1995) 1.13

Ultrastructure and immunohistochemical identification of the extracellular matrix of the chinchilla cochlea. Hear Res (1999) 1.09

Age-related decreases in endocochlear potential are associated with vascular abnormalities in the stria vascularis. Hear Res (1996) 1.07

Increased expression of MMP-2, MMP-9 (type IV collagenases/gelatinases), and MT1-MMP in canine X-linked Alport syndrome (XLAS). Kidney Int (2003) 1.05

Tissue inhibitors of metalloproteases: regulation and biological activities. Clin Exp Metastasis (2000) 1.03

Ultrastructural, physiological, and molecular defects in the inner ear of a gene-knockout mouse model for autosomal Alport syndrome. Hear Res (1998) 1.03

Inner ear defect similar to Alport's syndrome in the glomerulosclerosis mouse model Mpv17. Eur Arch Otorhinolaryngol (1996) 1.01

Insulin-dependent diabetic microangiopathy in the inner ear. Laryngoscope (1995) 1.01

Membrane topology of the 22 kDa integral peroxisomal membrane protein. FEBS Lett (1993) 0.99

Recent advances in the regulation of matrix metalloproteinase 2 activation: from basic research to clinical implication (Review). Oncol Rep (2002) 0.99

Course of renal injury in the Mpv17-deficient transgenic mouse. J Am Soc Nephrol (2000) 0.96

Age-related thickening of basement membrane in stria vascularis capillaries. Hear Res (1997) 0.96

Non-insulin-dependent diabetic microangiopathy in the inner ear. J Laryngol Otol (1999) 0.94

Immunohistochemical localization of basement membrane collagens and associated proteins in the murine cochlea. Hear Res (1996) 0.91

Glomerular pathology: recent advances. J Pathol (1998) 0.91

Proteoglycan arrays in the cochlear basement membrane. Hear Res (2001) 0.90

M-LP, Mpv17-like protein, has a peroxisomal membrane targeting signal comprising a transmembrane domain and a positively charged loop and up-regulates expression of the manganese superoxide dismutase gene. J Biol Chem (2002) 0.89

[Morphological changes in the inner ear of alport's syndrome (author's transl)]. Laryngol Rhinol Otol (Stuttg) (1976) 0.88

Loss of auditory function in transgenic Mpv17-deficient mice. Hear Res (1997) 0.87

A novel alternative spliced Mpv17-like protein isoform localizes in cytosol and is expressed in a kidney- and adult-specific manner. Exp Cell Res (2005) 0.86

The laminins in the murine inner ear: developmental transitions and expression in cochlear basement membranes. Hear Res (2001) 0.86

Localization of type IV collagen and laminin in the guinea pig inner ear. Ann Otol Rhinol Laryngol Suppl (1992) 0.86

Genetic disorders of transporters/channels in the inner ear and their relation to the kidney. Pediatr Nephrol (2004) 0.86

Temporal bone histopathology in alport syndrome. Laryngoscope (2004) 0.84

Cloning, mapping, genomic organization, and expression of mouse M-LP, a new member of the peroxisomal membrane protein Mpv17 domain family. Biochem Biophys Res Commun (2001) 0.84

A molecular look at the glomerular barrier. Nephron Exp Nephrol (2003) 0.83

Expression of the recessive glomerulosclerosis gene Mpv17 regulates MMP-2 expression in fibroblasts, the kidney, and the inner ear of mice. Mol Biol Cell (1998) 0.83

Oxidative stress in diabetic nephropathy: basic and clinical information. Curr Diab Rep (2001) 0.81

Enhanced gamma-glutamyl transpeptidase expression and superoxide production in Mpv17-/- glomerulosclerosis mice. Biol Chem (2001) 0.81

Localization of laminin isoforms in the guinea pig cochlea. Laryngoscope (1999) 0.81

Expression of the major basement membrane-associated proteins during postnatal development in the murine cochlea. Hear Res (1997) 0.79

Immunoglobulin deposition in thickened basement membranes of aging strial capillaries. Hear Res (1997) 0.78

TGF-beta1 induces aberrant laminin chain and collagen type IV isotype expression in the glomerular basement membrane. Nephron Exp Nephrol (2003) 0.78

Strial marginal cells play a role in basement membrane homeostasis: in vitro and in vivo evidence. Hear Res (2002) 0.78

Reactive oxygen species and glomerular injury. Kidney Blood Press Res (1996) 0.75

Ultrastructural and physiological defects in the cochlea of the Mpv17 mouse strain. A comparison between young and old adult animals. Hear Res (2001) 0.75

[Inner ear and diabetes mellitus diabetic mutant mice]. Laryngol Rhinol Otol (Stuttg) (1982) 0.75

Mpv37 mouse strain--a model for the relationship between the kidney and the inner ear. Adv Otorhinolaryngol (2002) 0.75