Published in Eur J Cancer on September 01, 2005
Murine models to evaluate novel and conventional therapeutic strategies for cancer. Am J Pathol (2007) 3.03
Translating animal research into clinical benefit. BMJ (2007) 2.25
A target-selected Apc-mutant rat kindred enhances the modeling of familial human colon cancer. Proc Natl Acad Sci U S A (2007) 1.81
Non-germline genetically engineered mouse models for translational cancer research. Nat Rev Cancer (2010) 1.80
APC and its modifiers in colon cancer. Adv Exp Med Biol (2009) 1.28
The anti-apoptotic and growth stimulatory actions of leptin in human colon cancer cells involves activation of JNK mitogen activated protein kinase, JAK2 and PI3 kinase/Akt. Int J Colorectal Dis (2006) 1.27
Coxibs and other nonsteroidal anti-inflammatory drugs in animal models of cancer chemoprevention. Cancer Prev Res (Phila) (2011) 1.20
A meta-analysis of threats to valid clinical inference in preclinical research of sunitinib. Elife (2015) 1.20
Aspirin and low-dose nitric oxide-donating aspirin increase life span in a Lynch syndrome mouse model. Cancer Prev Res (Phila) (2011) 1.19
Why animal studies are often poor predictors of human reactions to exposure. J R Soc Med (2009) 1.13
Epac1 is upregulated during neointima formation and promotes vascular smooth muscle cell migration. Am J Physiol Heart Circ Physiol (2008) 1.06
Mouse models for unraveling the importance of diet in colon cancer prevention. J Nutr Biochem (2010) 1.06
Look back in anger - what clinical studies tell us about preclinical work. ALTEX (2013) 1.04
Understanding phenotypic variation in rodent models with germline Apc mutations. Cancer Res (2013) 1.03
Morphological and molecular alterations in 1,2 dimethylhydrazine and azoxymethane induced colon carcinogenesis in rats. J Biomed Biotechnol (2010) 1.01
3,3'-diindolylmethane enhances the efficacy of butyrate in colon cancer prevention through down-regulation of survivin. Cancer Prev Res (Phila) (2009) 0.95
Gene expression profile and genomic alterations in colonic tumours induced by 1,2-dimethylhydrazine (DMH) in rats. BMC Cancer (2010) 0.94
Beef meat promotion of dimethylhydrazine-induced colorectal carcinogenesis biomarkers is suppressed by dietary calcium. Br J Nutr (2007) 0.93
Berberine potently attenuates intestinal polyps growth in ApcMin mice and familial adenomatous polyposis patients through inhibition of Wnt signalling. J Cell Mol Med (2013) 0.93
Dietary cooked navy beans and their fractions attenuate colon carcinogenesis in azoxymethane-induced ob/ob mice. Nutr Cancer (2008) 0.91
Supplementation by vitamin D compounds does not affect colonic tumor development in vitamin D sufficient murine models. Arch Biochem Biophys (2011) 0.90
Randomized phase II trial of sulindac, atorvastatin, and prebiotic dietary fiber for colorectal cancer chemoprevention. Cancer Prev Res (Phila) (2011) 0.89
Chronic inflammation and the development of malignancy in the GI tract. Trends Immunol (2015) 0.87
Calcium prevents tumorigenesis in a mouse model of colorectal cancer. PLoS One (2011) 0.87
The use of systematic reviews and reporting guidelines to advance the implementation of the 3Rs. J Am Assoc Lab Anim Sci (2015) 0.86
Mthfd1 is a modifier of chemically induced intestinal carcinogenesis. Carcinogenesis (2010) 0.86
Sporadic colon cancer murine models demonstrate the value of autoantibody detection for preclinical cancer diagnosis. Sci Rep (2013) 0.85
Selenoprotein P status correlates to cancer-specific mortality in renal cancer patients. PLoS One (2012) 0.85
Polyethylene glycol, unique among laxatives, suppresses aberrant crypt foci, by elimination of cells. Scand J Gastroenterol (2006) 0.84
C57BL/KsJ-db/db-Apc mice exhibit an increased incidence of intestinal neoplasms. Int J Mol Sci (2011) 0.83
Silibinin, a natural flavonoid, modulates the early expression of chemoprevention biomarkers in a preclinical model of colon carcinogenesis. Int J Oncol (2012) 0.83
Nrf2 status affects tumor growth, HDAC3 gene promoter associations, and the response to sulforaphane in the colon. Clin Epigenetics (2015) 0.82
Calcium carbonate suppresses haem toxicity markers without calcium phosphate side effects on colon carcinogenesis. Br J Nutr (2010) 0.81
Induction of colonic aberrant crypts in mice by feeding apparent N-nitroso compounds derived from hot dogs. Nutr Cancer (2012) 0.81
Chemical carcinogenesis of the gastrointestinal tract in rodents: an overview with emphasis on NTP carcinogenesis bioassays. Toxicol Pathol (2009) 0.80
Role of hepatic and intestinal p450 enzymes in the metabolic activation of the colon carcinogen azoxymethane in mice. Chem Res Toxicol (2014) 0.80
BID mediates selective killing of APC-deficient cells in intestinal tumor suppression by nonsteroidal antiinflammatory drugs. Proc Natl Acad Sci U S A (2014) 0.80
Animal models of human colorectal cancer: Current status, uses and limitations. World J Gastroenterol (2015) 0.80
Expression of LGR-5, MSI-1 and DCAMKL-1, putative stem cell markers, in the early phases of 1,2-dimethylhydrazine-induced rat colon carcinogenesis: correlation with nuclear β-catenin. BMC Cancer (2013) 0.78
Novel diet-related mouse model of colon cancer parallels human colon cancer. World J Gastrointest Oncol (2014) 0.78
Context specific transcription factor prediction. Ann Biomed Eng (2007) 0.78
Can animal data translate to innovations necessary for a new era of patient-centred and individualised healthcare? Bias in preclinical animal research. BMC Med Ethics (2015) 0.78
Current animal models of bladder cancer: Awareness of translatability (Review). Exp Ther Med (2014) 0.78
Sulindac, 3,3'-diindolylmethane and curcumin reduce carcinogenesis in the Pirc rat, an Apc-driven model of colon carcinogenesis. BMC Cancer (2015) 0.78
Grape compounds suppress colon cancer stem cells in vitro and in a rodent model of colon carcinogenesis. BMC Complement Altern Med (2016) 0.77
Effect of a high-fat diet in development of colonic adenoma in an animal model. World J Gastroenterol (2014) 0.77
Unlocking Aspirin's Chemopreventive Activity: Role of Irreversibly Inhibiting Platelet Cyclooxygenase-1. Cancer Prev Res (Phila) (2016) 0.76
Inhibitory effect of a standardized pomegranate fruit extract on Wnt signalling in 1, 2-dimethylhydrazine induced rat colon carcinogenesis. Dig Dis Sci (2013) 0.76
The relevance of the colon to zinc nutrition. Nutrients (2015) 0.76
The patients knowledge about the role of calcium in the primary prevention of colorectal cancer. Contemp Oncol (Pozn) (2012) 0.75
The Effect of Sex on the Azoxymethane/Dextran Sulfate Sodium-treated Mice Model of Colon Cancer. J Cancer Prev (2016) 0.75
Suppressive effect of zinc on the formation of colonic preneoplastic lesions in the mouse fed high levels of dietary iron. Toxicol Res (2012) 0.75
Food-grade TiO2 impairs intestinal and systemic immune homeostasis, initiates preneoplastic lesions and promotes aberrant crypt development in the rat colon. Sci Rep (2017) 0.75
Bias During the Evaluation of Animal Studies? Animals (Basel) (2012) 0.75
Methanolic extract of white asparagus shoots activates TRAIL apoptotic death pathway in human cancer cells and inhibits colon carcinogenesis in a preclinical model. Int J Oncol (2013) 0.75
Ultrasound imaging of splenomegaly as a proxy to monitor colon tumor development in Apc(min716/+) mice. Cancer Med (2016) 0.75
Point: From animal models to prevention of colon cancer. Systematic review of chemoprevention in min mice and choice of the model system. Cancer Epidemiol Biomarkers Prev (2003) 2.76
Maternal outcome after conservative treatment of placenta accreta. Obstet Gynecol (2010) 2.58
CX-4945, an orally bioavailable selective inhibitor of protein kinase CK2, inhibits prosurvival and angiogenic signaling and exhibits antitumor efficacy. Cancer Res (2010) 2.06
Processed meat and colorectal cancer: a review of epidemiologic and experimental evidence. Nutr Cancer (2008) 1.81
Systems-based design of bi-ligand inhibitors of oxidoreductases: filling the chemical proteomic toolbox. Chem Biol (2004) 1.52
Assessment of the pathogenic potential of two Listeria monocytogenes human faecal carriage isolates. Microbiology (2002) 1.49
Expression of truncated Internalin A is involved in impaired internalization of some Listeria monocytogenes isolates carried asymptomatically by humans. Infect Immun (2003) 1.29
Fertility and pregnancy outcomes following conservative treatment for placenta accreta. Hum Reprod (2010) 1.11
Risks associated with laparoscopic entry: guidelines for clinical practice from the French College of Gynaecologists and Obstetricians. Eur J Obstet Gynecol Reprod Biol (2011) 1.10
European registry of babies born to mothers with antiphospholipid syndrome. Ann Rheum Dis (2012) 0.95
Unprecedented selectivity and structural determinants of a new class of protein kinase CK2 inhibitors in clinical trials for the treatment of cancer. Biochemistry (2011) 0.91
Prevention of complications related to the use of prosthetic meshes in prolapse surgery: guidelines for clinical practice. Eur J Obstet Gynecol Reprod Biol (2012) 0.89
Evidence for multiple levels of regulation of Oenococcus oeni clpP-clpL locus expression in response to stress. J Bacteriol (2004) 0.86
Instrumental delivery: clinical practice guidelines from the French College of Gynaecologists and Obstetricians. Eur J Obstet Gynecol Reprod Biol (2011) 0.86
Butyrate restores motile function and actin cytoskeletal network integrity in apc mutated mouse colon epithelial cells. Nutr Cancer (2003) 0.84
Potential use of selective and nonselective Pim kinase inhibitors for cancer therapy. J Med Chem (2012) 0.82
Risk factors for severe neonatal acidosis. Obstet Gynecol (2011) 0.82
Apc+/Min colonic epithelial cells express TNF receptors and ICAM-1 when they are co-cultured with large intestine intra-epithelial lymphocytes. Cell Immunol (2003) 0.81
Anti-NMDA Receptor Encephalitis During Pregnancy: A Case Report. Medicine (Baltimore) (2015) 0.81
Using middle cerebral artery peak systolic velocity to time in utero transfusions in fetomaternal hemorrhage. Obstet Gynecol (2010) 0.80
Altered SK3/KCa2.3-mediated migration in adenomatous polyposis coli (Apc) mutated mouse colon epithelial cells. Biochem Biophys Res Commun (2010) 0.80
Large intestine intraepithelial lymphocytes from Apc+/+ and Apc+/Min mice and their modulation by indigestible carbohydrates: the IL-15/IL-15R alpha complex and CD4+ CD25+ T cells are the main targets. Cancer Immunol Immunother (2005) 0.80
Bisphenol a and its chlorinated derivatives in human colostrum. Environ Sci Technol (2013) 0.79
Improving perinatal Group B streptococcus screening with process indicators. J Eval Clin Pract (2011) 0.78
Very preterm birth: who has access to antenatal corticosteroid therapy? Paediatr Perinat Epidemiol (2010) 0.78
Metabolic bioactivation of oestradiol-17beta (E2beta) in mouse colon epithelial cells bearing ApcMin mutation. Steroids (2010) 0.77
ADAMTS13 deficiency in severe postpartum HELLP syndrome. Br J Haematol (2013) 0.77
Synthesis and SAR of inhibitors of protein kinase CK2: novel tricyclic quinoline analogs. Bioorg Med Chem Lett (2011) 0.76
High potency of bioactivation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in mouse colon epithelial cells with Apc(Min) mutation. Mutat Res (2008) 0.76
Causes of thrombocytopenia in pregnancy. Eur J Obstet Gynecol Reprod Biol (2007) 0.75
Complications of laparoscopy: an inquiry about closed versus open-entry technique. Am J Obstet Gynecol (2005) 0.75
Diagnosis of lupus after stillbirth. Am J Obstet Gynecol (2006) 0.75
Gestational weight gain: arguments for a transgenerational weight-control process. Am J Clin Nutr (2012) 0.75
Causes of thrombocytopenia in triplet pregnancies. Am J Obstet Gynecol (2004) 0.75
Short-term beef consumption promotes systemic oxidative stress, TMAO formation and inflammation in rats, and dietary fat content modulates these effects. Food Funct (2016) 0.75
High-Dose Methylprednisolone to Prevent Platelet Decline in Preeclampsia: A Randomized Controlled Trial. Obstet Gynecol (2016) 0.75
Association Between Planned Cesarean Delivery and Neonatal Mortality and Morbidity in Twin Pregnancies. Obstet Gynecol (2017) 0.75