Published in Neurosci Lett on May 25, 1992
Inactivation properties of voltage-gated K+ channels altered by presence of beta-subunit. Nature (1994) 4.38
Anomalous rectification in the metacerebral giant cells and its consequences for synaptic transmission. J Physiol (1966) 3.18
Calcium influx in active Aplysia neurones detected by injected aequorin. Nat New Biol (1973) 2.63
Tetanus toxin: primary structure, expression in E. coli, and homology with botulinum toxins. EMBO J (1986) 2.62
A guide to the use of pore-forming toxins for controlled permeabilization of cell membranes. Med Microbiol Immunol (1993) 2.37
Acceptors for botulinum neurotoxin reside on motor nerve terminals and mediate its internalization. Nature (1984) 2.02
Functional repair of motor endplates after botulinum neurotoxin type A poisoning: biphasic switch of synaptic activity between nerve sprouts and their parent terminals. Proc Natl Acad Sci U S A (1999) 1.99
Interaction of 125I-labeled botulinum neurotoxins with nerve terminals. I. Ultrastructural autoradiographic localization and quantitation of distinct membrane acceptors for types A and B on motor nerves. J Cell Biol (1986) 1.83
Acetylcholine receptor and ion conductance modulator sites at the murine neuromuscular junction: evidence from specific toxin reactions. Proc Natl Acad Sci U S A (1973) 1.82
Botulinum neurotoxin C1 cleaves both syntaxin and SNAP-25 in intact and permeabilized chromaffin cells: correlation with its blockade of catecholamine release. Biochemistry (1996) 1.77
Central action of dendrotoxin: selective reduction of a transient K conductance in hippocampus and binding to localized acceptors. Proc Natl Acad Sci U S A (1986) 1.72
Heterosynaptic facilitation in neurones of the abdominal ganglion of Aplysia depilans. J Physiol (1965) 1.62
VAMP-2 and cellubrevin are expressed in pancreatic beta-cells and are essential for Ca(2+)-but not for GTP gamma S-induced insulin secretion. EMBO J (1995) 1.56
SNAP-25 is expressed in islets of Langerhans and is involved in insulin release. J Cell Biol (1995) 1.48
Characterization of SNARE protein expression in beta cell lines and pancreatic islets. Endocrinology (1996) 1.45
Clostridium botulinum type C produces a novel ADP-ribosyltransferase distinct from botulinum C2 toxin. FEBS Lett (1987) 1.44
Glial heterogeneity in expression of the inwardly rectifying K(+) channel, Kir4.1, in adult rat CNS. Glia (2000) 1.43
Tetanus toxin and botulinum toxins type A and B inhibit glutamate, gamma-aminobutyric acid, aspartate, and met-enkephalin release from synaptosomes. Clues to the locus of action. J Biol Chem (1992) 1.43
Acetylcholine receptors: topographic distribution and pharmacological properties of two receptor types on a single molluscan neurone. J Physiol (1972) 1.42
Tetanus toxin is a zinc protein and its inhibition of neurotransmitter release and protease activity depend on zinc. EMBO J (1992) 1.39
Mechanism of heterosynaptic facilitation in the giant cell of the abdominal ganglion of Aplysia depilans. J Physiol (1965) 1.38
Multiple interneuronal afferents to the giant cells in Aplysia. J Physiol (1975) 1.35
Primary structure of a beta subunit of alpha-dendrotoxin-sensitive K+ channels from bovine brain. Proc Natl Acad Sci U S A (1994) 1.34
Preparation and characterisation of homogeneous neurotoxin type A from Clostridium botulinum. Its inhibitory action on neuronal release of acetylcholine in the absence and presence of beta-bungarotoxin. Eur J Biochem (1982) 1.34
Transmission in invertebrate and vertebrate ganglia. Physiol Rev (1967) 1.32
Input organization of two symmetrical giant cells in the snail brain. J Physiol (1966) 1.29
Vesicle exocytosis stimulated by alpha-latrotoxin is mediated by latrophilin and requires both external and stored Ca2+. EMBO J (1998) 1.28
Recovery of human fibroblasts from attack by the pore-forming alpha-toxin of Staphylococcus aureus. Microb Pathog (1994) 1.27
Subunit combinations defined for K+ channel Kv1 subtypes in synaptic membranes from bovine brain. Biochemistry (1997) 1.27
Differences in the protease activities of tetanus and botulinum B toxins revealed by the cleavage of vesicle-associated membrane protein and various sized fragments. Biochemistry (1994) 1.27
Protein kinase B stimulates the translocation of GLUT4 but not GLUT1 or transferrin receptors in 3T3-L1 adipocytes by a pathway involving SNAP-23, synaptobrevin-2, and/or cellubrevin. J Biol Chem (1999) 1.25
Radioiodination of botulinum neurotoxin type A with retention of biological activity and its binding to brain synaptosomes. Eur J Biochem (1983) 1.25
Binding of perhydro-histrionicotoxin to the postsynaptic membrane of skeletal muscle in relation to its blockage of acetylcholine-induced depolarization. Mol Pharmacol (1977) 1.24
The effects of purified botulinum neurotoxin type A on cholinergic, adrenergic and non-adrenergic, atropine-resistant autonomic neuromuscular transmission. Neuroscience (1982) 1.24
Subunit composition of Kv1 channels in human CNS. J Neurochem (1999) 1.22
Studies on the oestrogen sulphatase and arylsulphatase C activities of rat liver. Biochem J (1972) 1.22
Selective killing of human monocytes and cytokine release provoked by sphingomyelinase (beta-toxin) of Staphylococcus aureus. Infect Immun (1996) 1.22
Antibodies specific for distinct Kv subunits unveil a heterooligomeric basis for subtypes of alpha-dendrotoxin-sensitive K+ channels in bovine brain. Biochemistry (1994) 1.20
Staphylococcus aureus alpha-toxin. Production of functionally intact, site-specifically modifiable protein by introduction of cysteine at positions 69, 130, and 186. J Biol Chem (1993) 1.19
Botulinum neurotoxin and dendrotoxin as probes for studies on transmitter release. J Physiol (Paris) (1984) 1.19
Quantal release of acetylcholine examined by current fluctuation analysis at an identified neuro-neuronal synapse of Aplysia. Proc Natl Acad Sci U S A (1980) 1.18
Oligomeric properties of alpha-dendrotoxin-sensitive potassium ion channels purified from bovine brain. Biochemistry (1992) 1.18
Transmission abolished on a cholinergic synapse after injection of acetylcholinesterase into the presynaptic neurone. Nature (1974) 1.18
Botulinum neurotoxin type B. Its purification, radioiodination and interaction with rat-brain synaptosomal membranes. Eur J Biochem (1986) 1.17
Rapid detection of Salmonella sp. by means of a combination of selective enrichment broth and MALDI-TOF MS. Eur J Clin Microbiol Infect Dis (2011) 1.17
SNAP-23 is not cleaved by botulinum neurotoxin E and can replace SNAP-25 in the process of insulin secretion. J Biol Chem (1997) 1.17
Non vesicular release of neurotransmitter. Physiol Rev (1982) 1.16
Multiple forms of dipeptidases in normal human intestinal mucosa and in mucosa from children with coeliac disease. Clin Chim Acta (1969) 1.15
Direct control of exocytosis by receptor-mediated activation of the heterotrimeric GTPases Gi and G(o) or by the expression of their active G alpha subunits. EMBO J (1995) 1.15
Two acceptor sub-types for dendrotoxin in chick synaptic membranes distinguishable by beta-bungarotoxin. Eur J Biochem (1986) 1.12
Sodium pump stoichiometry in Aplysia neurones from simultaneous current and tracer measurements. Nature (1974) 1.12
alpha subunit compositions of Kv1.1-containing K+ channel subtypes fractionated from rat brain using dendrotoxins. Eur J Biochem (1999) 1.11
Dendrotoxin acceptor from bovine synaptic plasma membranes. Binding properties, purification and subunit composition of a putative constituent of certain voltage-activated K+ channels. Biochem J (1989) 1.10
The tetanus toxin light chain inhibits exocytosis. FEBS Lett (1989) 1.09
Preparation of neurotoxic 3H-beta-bungarotoxin: demonstration of saturable binding to brain synapses and its inhibition by toxin I. Eur J Biochem (1982) 1.08
Different forms of streptolysin O produced by Streptococcus pyogenes and by Escherichia coli expressing recombinant toxin: cleavage by streptococcal cysteine protease. Infect Immun (1995) 1.07
Characterization of the inhibitory action of botulinum neurotoxin type A on the release of several transmitters from rat cerebrocortical synaptosomes. J Neurochem (1988) 1.05
Brain and muscle nicotinic acetylcholine receptors are different but homologous proteins. Proc Natl Acad Sci U S A (1985) 1.05
Stoichiometry of the ligand-binding sites in the acetylcholine-receptor oligomer from muscle and from electric organ. Measurement by affinity alkylation with bromoacetylcholine. Eur J Biochem (1980) 1.05
Interaction of 125I-labeled botulinum neurotoxins with nerve terminals. II. Autoradiographic evidence for its uptake into motor nerves by acceptor-mediated endocytosis. J Cell Biol (1986) 1.04
Identification of residues in dendrotoxin K responsible for its discrimination between neuronal K+ channels containing Kv1.1 and 1.2 alpha subunits. Eur J Biochem (1999) 1.03
Minimal essential domains specifying toxicity of the light chains of tetanus toxin and botulinum neurotoxin type A. J Biol Chem (1992) 1.03
Mast cell degranulating peptide and dendrotoxin selectively inhibit a fast-activating potassium current and bind to common neuronal proteins. Neuroscience (1987) 1.03
Electrophysiological and neurobiochemical evidence for the blockade of a potassium channel by dendrotoxin. Naunyn Schmiedebergs Arch Pharmacol (1985) 1.02
Prominent location of a K+ channel containing the alpha subunit Kv 1.2 in the basket cell nerve terminals of rat cerebellum. Neuroscience (1993) 1.02
Soluble N-ethylmaleimide-sensitive-factor attachment protein and N-ethylmaleimide-insensitive factors are required for Ca2+-stimulated exocytosis of insulin. Biochem J (1996) 1.02
Altered pore-forming properties of proteolytically nicked staphylococcal alpha-toxin. J Biol Chem (1993) 1.02
Potassium channels in mouse neonate dorsal root ganglion cells: a patch-clamp study. Brain Res (1987) 1.01
Episodic ataxia type-1 mutations in the Kv1.1 potassium channel display distinct folding and intracellular trafficking properties. J Biol Chem (2001) 1.01
Novel aspect of amphotericin B action: accumulation in human monocytes potentiates killing of phagocytosed Candida albicans. Antimicrob Agents Chemother (1994) 1.01
Uncoupling of electrotonic synapses by calcium. Proc Natl Acad Sci U S A (1978) 1.00
The acetylcholine receptor and the ionic conductance modulation system of skeletal muscle. Exp Neurol (1975) 1.00
Cyclic AMP induced by serotonin modulates the activity of an identified synapse in Aplysia by facilitating the active permeability to calcium. Brain Res (1977) 0.99
Electrical transmission among neurons in the buccal ganglion of a mollusc, Navanax inermis. J Gen Physiol (1970) 0.99
Habituation at the synaptic level in Aplysia. Nature (1966) 0.99
Complete purification of beta-bungarotoxin. Characterization of its action and that of tityustoxin on synaptosomal accumulation and release of acetylcholine. Biochim Biophys Acta (1980) 0.98
Cyclic ADP-ribose and calcium-induced calcium release regulate neurotransmitter release at a cholinergic synapse of Aplysia. J Physiol (1998) 0.98
Dynamics of Ca2+ and guanosine 5'-[gamma-thio]triphosphate action on insulin secretion from alpha-toxin-permeabilized HIT-T15 cells. Biochem J (1994) 0.98
Metabolism of sodium oestrone ( 35 S)sulphate in the rat. Biochem J (1971) 0.98
Alpha-dendrotoxin acceptor from bovine brain is a K+ channel protein. Evidence from the N-terminal sequence of its larger subunit. J Biol Chem (1990) 0.97
Involvement of the constituent chains of botulinum neurotoxins A and B in the blockade of neurotransmitter release. Eur J Biochem (1988) 0.97
Nicotinic acetylcholine receptor from chick optic lobe. Proc Natl Acad Sci U S A (1982) 0.97
Involvement of neuronal acceptors for dendrotoxin in its convulsive action in rat brain. Biochem J (1986) 0.96
Exogenous mRNA encoding tetanus or botulinum neurotoxins expressed in Aplysia neurons. Proc Natl Acad Sci U S A (1990) 0.96
Botulinum A and the light chain of tetanus toxins inhibit distinct stages of Mg.ATP-dependent catecholamine exocytosis from permeabilised chromaffin cells. Eur J Biochem (1994) 0.96
A single mutation in the recombinant light chain of tetanus toxin abolishes its proteolytic activity and removes the toxicity seen after reconstitution with native heavy chain. Biochemistry (1994) 0.96
Presynaptic transmitter content controls the number of quanta released at a neuro-neuronal cholinergic synapse. Proc Natl Acad Sci U S A (1986) 0.95
Size of acetylcholine receptors in the membrane. An improved version of the radiation inactivation method. Biochemistry (1982) 0.94
Transmitter release: ruthenium red used to demonstrate a possible role of sialic acid containing substrates. J Physiol (1979) 0.94
Productive and non-productive binding of botulinum neurotoxin A to motor nerve endings are distinguished by its heavy chain. J Neurosci Res (1996) 0.93
Cloning and functional expression of dendrotoxin K from black mamba, a K+ channel blocker. Biochemistry (1993) 0.93
Binding, oligomerization, and pore formation by streptolysin O in erythrocytes and fibroblast membranes: detection of nonlytic polymers. Infect Immun (1995) 0.93
Central neuronal response to the activation of osmoreceptors in the osphradium of Aplysia. J Exp Biol (1969) 0.93
Light chain of tetanus toxin intracellularly inhibits acetylcholine release at neuro-neuronal synapses, and its internalization is mediated by heavy chain. FEBS Lett (1989) 0.91