Mortalin/GRP75 promotes release of membrane vesicles from immune attacked cells and protection from complement-mediated lysis.

PubWeight™: 1.01‹?› | Rank: Top 15%

🔗 View Article (PMID 16091382)

Published in Int Immunol on August 09, 2005

Authors

David Pilzer1, Zvi Fishelson

Author Affiliations

1: Department of Cell and Developmental Biology, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel.

Articles citing this

Exosomes in cancer development, metastasis, and drug resistance: a comprehensive review. Cancer Metastasis Rev (2013) 2.46

Extracellular heat shock proteins, cellular export vesicles, and the Stress Observation System: a form of communication during injury, infection, and cell damage. It is never known how far a controversial finding will go! Dedicated to Ferruccio Ritossa. Cell Stress Chaperones (2010) 1.69

Emission of membrane vesicles: roles in complement resistance, immunity and cancer. Springer Semin Immunopathol (2005) 1.39

On the brotherhood of the mitochondrial chaperones mortalin and heat shock protein 60. Cell Stress Chaperones (2006) 1.33

Membrane attack by complement: the assembly and biology of terminal complement complexes. Immunol Res (2011) 1.28

Secretion modification region-derived peptide disrupts HIV-1 Nef's interaction with mortalin and blocks virus and Nef exosome release. J Virol (2011) 0.97

Activation of macrophages by P2X7-induced microvesicles from myeloid cells is mediated by phospholipids and is partially dependent on TLR4. J Immunol (2010) 0.97

Myofiber stress-response in myositis: parallel investigations on patients and experimental animal models of muscle regeneration and systemic inflammation. Arthritis Res Ther (2010) 0.94

A subunit of eukaryotic translation initiation factor 2α-phosphatase (CreP/PPP1R15B) regulates membrane traffic. J Biol Chem (2012) 0.90

Serum deprivation elevates the levels of microvesicles with different size distributions and selectively enriched proteins in human myeloma cells in vitro. Acta Pharmacol Sin (2013) 0.89

Extracellular heat shock proteins: a new location, a new function. Shock (2013) 0.85

Caveolin-1 and dynamin-2 are essential for removal of the complement C5b-9 complex via endocytosis. J Biol Chem (2012) 0.84

Mortalin, apoptosis, and neurodegeneration. Biomolecules (2012) 0.82

Expression analysis of heat shock protein genes during Aeromonas hydrophila infection in rohu, Labeo rohita, with special reference to molecular characterization of Grp78. Cell Stress Chaperones (2014) 0.81

Role of Extracellular Vesicles in Hematological Malignancies. Biomed Res Int (2015) 0.81

Circulating mortalin autoantibody--a new serological marker of liver cirrhosis. Cell Stress Chaperones (2015) 0.80

Mortalin/GRP75 binds to complement C9 and plays a role in resistance to complement-dependent cytotoxicity. J Biol Chem (2014) 0.79

Retinal Pigment Epithelial Cells Mitigate the Effects of Complement Attack by Endocytosis of C5b-9. J Immunol (2015) 0.78

The mystery behind membrane insertion: a review of the complement membrane attack complex. Philos Trans R Soc Lond B Biol Sci (2017) 0.78

Exosomal microRNA Biomarkers: Emerging Frontiers in Colorectal and Other Human Cancers. Expert Rev Mol Diagn (2016) 0.76

Extracellular Vesicles in Brain Tumor Progression. Cell Mol Neurobiol (2016) 0.76

Complement susceptibility in glutamine deprived breast cancer cells. Cell Div (2007) 0.75

Regulation of perforin lysis: implications for protein disulfide isomerase proteins. Cell Immunol (2009) 0.75

Extracellular vesicle-mediated suicide mRNA/protein delivery inhibits glioblastoma tumor growth in vivo. Cancer Gene Ther (2016) 0.75

Articles by these authors

Emission of membrane vesicles: roles in complement resistance, immunity and cancer. Springer Semin Immunopathol (2005) 1.39

Inhibition of the complement membrane attack complex by Schistosoma mansoni paramyosin. Infect Immun (2003) 1.25

Cell signals transduced by complement. Mol Immunol (2004) 1.21

Live cell imaging of outward and inward vesiculation induced by the complement c5b-9 complex. J Biol Chem (2007) 1.03

Mapping of the complement C9 binding domain in paramyosin of the blood fluke Schistosoma mansoni. Int J Parasitol (2006) 0.98

Cancer resistance to complement-dependent cytotoxicity (CDC): Problem-oriented research and development. Mol Immunol (2009) 0.98

Identification of immune-relevant genes in histoincompatible rejecting colonies of the tunicate Botryllus schlosseri. Dev Comp Immunol (2007) 0.92

Elevated levels of mitochondrial mortalin and cytosolic HSP70 in blood as risk factors in patients with colorectal cancer. Int J Cancer (2013) 0.90

Mortalin inhibitors sensitize K562 leukemia cells to complement-dependent cytotoxicity. Int J Cancer (2010) 0.86

Urochordate histoincompatible interactions activate vertebrate-like coagulation system components. PLoS One (2008) 0.85

Programmed necrotic cell death induced by complement involves a Bid-dependent pathway. J Immunol (2009) 0.85

Caveolin-1 and dynamin-2 are essential for removal of the complement C5b-9 complex via endocytosis. J Biol Chem (2012) 0.84

Schistosoma japonicum migration through mouse skin compared histologically and immunologically with S. mansoni. Parasitol Res (2005) 0.84

Extracellular phosphorylation of C9 by protein kinase CK2 regulates complement-mediated lysis. Eur J Immunol (2005) 0.83

Increased sensitivity of early apoptotic cells to complement-mediated lysis. Eur J Immunol (2004) 0.82

Involvement of the c-jun N-terminal kinases JNK1 and JNK2 in complement-mediated cell death. Mol Immunol (2009) 0.81

Quantification of complement C5b-9 binding to cells by flow cytometry. Methods Mol Biol (2014) 0.78

Killing of schistosomes by elastase and hydrogen peroxide: implications for leukocyte-mediated schistosome killing. J Parasitol (2003) 0.78

A novel mutation in the C3 gene and recurrent invasive pneumococcal infection: a clue for vaccine development. Mol Immunol (2011) 0.78

A role for the NF-κB pathway in cell protection from complement-dependent cytotoxicity. J Immunol (2012) 0.77

'Rejected' vs. 'rejecting' transcriptomes in allogeneic challenged colonial urochordates. Mol Immunol (2010) 0.76

Clostridium difficile infection and partial membrane cofactor protein (CD46) deficiency. Isr Med Assoc J (2012) 0.75

Construction and characterization of recombinant human C9 or C7 linked to single chain Fv directed to CD25. Mol Immunol (2013) 0.75