Published in Ann N Y Acad Sci on June 01, 2005
Regulation of lactate production at the onset of ischaemia is independent of mitochondrial NADH/NAD+: insights from in silico studies. J Physiol (2005) 0.97
Modeling cardiac ischemia. Ann N Y Acad Sci (2006) 0.95
Modeling of spatial metabolite distributions in the cardiac sarcomere. Biophys J (2007) 0.89
Parallel activation of mitochondrial oxidative metabolism with increased cardiac energy expenditure is not dependent on fatty acid oxidation in pigs. J Physiol (2006) 0.80
Myocardial fatty acid metabolism in health and disease. Physiol Rev (2010) 4.49
Mitofusin-2 maintains mitochondrial structure and contributes to stress-induced permeability transition in cardiac myocytes. Mol Cell Biol (2011) 2.23
Coding region polyadenylation generates a truncated tRNA synthetase that counters translation repression. Cell (2012) 2.06
From mitochondrial ion channels to arrhythmias in the heart: computational techniques to bridge the spatio-temporal scales. Philos Trans A Math Phys Eng Sci (2008) 2.05
Impaired myocardial metabolic reserve and substrate selection flexibility during stress in patients with idiopathic dilated cardiomyopathy. Am J Physiol Heart Circ Physiol (2007) 1.86
Perilipin 5, a lipid droplet-associated protein, provides physical and metabolic linkage to mitochondria. J Lipid Res (2011) 1.79
Carnitine palmitoyl transferase-I inhibition prevents ventricular remodeling and delays decompensation in pacing-induced heart failure. Cardiovasc Res (2005) 1.70
Role of diet and fuel overabundance in the development and progression of heart failure. Cardiovasc Res (2008) 1.70
Impaired myocardial fatty acid oxidation and reduced protein expression of retinoid X receptor-alpha in pacing-induced heart failure. Circulation (2002) 1.65
Bioinformatic profiling of the transcriptional response of adult rat cardiomyocytes to distinct fatty acids. J Lipid Res (2008) 1.63
Fish oil, but not flaxseed oil, decreases inflammation and prevents pressure overload-induced cardiac dysfunction. Cardiovasc Res (2008) 1.62
Low carbohydrate/high-fat diet attenuates cardiac hypertrophy, remodeling, and altered gene expression in hypertension. Hypertension (2006) 1.56
Cardiomyocyte deletion of mitofusin-1 leads to mitochondrial fragmentation and improves tolerance to ROS-induced mitochondrial dysfunction and cell death. Am J Physiol Heart Circ Physiol (2011) 1.53
Differential effects of saturated and unsaturated fatty acid diets on cardiomyocyte apoptosis, adipose distribution, and serum leptin. Am J Physiol Heart Circ Physiol (2006) 1.52
Validation of echocardiographic methods for assessing left ventricular dysfunction in rats with myocardial infarction. Am J Physiol Heart Circ Physiol (2004) 1.52
CVT-4325 inhibits myocardial fatty acid uptake and improves left ventricular systolic function without increasing myocardial oxygen consumption in dogs with chronic heart failure. Cardiovasc Drugs Ther (2007) 1.52
Cardiac energy metabolism in obesity. Circ Res (2007) 1.51
Dietary supplementation with omega-3 PUFA increases adiponectin and attenuates ventricular remodeling and dysfunction with pressure overload. Cardiovasc Res (2007) 1.50
Paradoxical downregulation of the glucose oxidation pathway despite enhanced flux in severe heart failure. J Mol Cell Cardiol (2004) 1.49
Modulating fatty acid oxidation in heart failure. Cardiovasc Res (2011) 1.37
omega-3 polyunsaturated fatty acid supplementation for the treatment of heart failure: mechanisms and clinical potential. Cardiovasc Res (2009) 1.32
Dietary omega-3 fatty acids alter cardiac mitochondrial phospholipid composition and delay Ca2+-induced permeability transition. J Mol Cell Cardiol (2009) 1.28
High-fat diet prevents cardiac hypertrophy and improves contractile function in the hypertensive dahl salt-sensitive rat. Clin Exp Pharmacol Physiol (2005) 1.24
Diabetes or peroxisome proliferator-activated receptor alpha agonist increases mitochondrial thioesterase I activity in heart. J Lipid Res (2007) 1.20
Concentration of solutes in the renal inner medulla: interstitial hyaluronan as a mechano-osmotic transducer. Am J Physiol Renal Physiol (2003) 1.16
Mitofusins 1 and 2 are essential for postnatal metabolic remodeling in heart. Circ Res (2012) 1.16
Ranolazine, a partial fatty acid oxidation (pFOX) inhibitor, improves left ventricular function in dogs with chronic heart failure. J Card Fail (2002) 1.16
Treatment with docosahexaenoic acid, but not eicosapentaenoic acid, delays Ca2+-induced mitochondria permeability transition in normal and hypertrophied myocardium. J Pharmacol Exp Ther (2010) 1.15
Mechanistic model of cardiac energy metabolism predicts localization of glycolysis to cytosolic subdomain during ischemia. Am J Physiol Heart Circ Physiol (2005) 1.14
Dietary supplementation with docosahexaenoic acid, but not eicosapentaenoic acid, dramatically alters cardiac mitochondrial phospholipid fatty acid composition and prevents permeability transition. Biochim Biophys Acta (2010) 1.14
High fructose diet increases mortality in hypertensive rats compared to a complex carbohydrate or high fat diet. Am J Hypertens (2007) 1.14
Effects of a high saturated fat diet on cardiac hypertrophy and dysfunction in response to pressure overload. J Card Fail (2008) 1.13
Short-term treatment with ranolazine improves mechanical efficiency in dogs with chronic heart failure. Circ Res (2002) 1.12
Cardiomyocyte-specific perilipin 5 overexpression leads to myocardial steatosis and modest cardiac dysfunction. J Lipid Res (2013) 1.12
The cardioprotective effects of fish oil during pressure overload are blocked by high fat intake: role of cardiac phospholipid remodeling. Hypertension (2009) 1.11
Regulation of pyruvate dehydrogenase activity and citric acid cycle intermediates during high cardiac power generation. J Physiol (2004) 1.10
Assessment of cardiac proteome dynamics with heavy water: slower protein synthesis rates in interfibrillar than subsarcolemmal mitochondria. Am J Physiol Heart Circ Physiol (2013) 1.10
A high-fat diet increases adiposity but maintains mitochondrial oxidative enzymes without affecting development of heart failure with pressure overload. Am J Physiol Heart Circ Physiol (2009) 1.10
Moderate severity heart failure does not involve a downregulation of myocardial fatty acid oxidation. Am J Physiol Heart Circ Physiol (2004) 1.09
Effects of chronic activation of peroxisome proliferator-activated receptor-alpha or high-fat feeding in a rat infarct model of heart failure. Am J Physiol Heart Circ Physiol (2005) 1.08
Preserved protein synthesis in the heart in response to acute fasting and chronic food restriction despite reductions in liver and skeletal muscle. Am J Physiol Endocrinol Metab (2008) 1.08
Malonyl coenzyme a decarboxylase inhibition protects the ischemic heart by inhibiting fatty acid oxidation and stimulating glucose oxidation. Circ Res (2004) 1.08
Too much or not enough of a good thing? Cardiac glucolipotoxicity versus lipoprotection. J Mol Cell Cardiol (2010) 1.07
Thermal model for fast simulation during magnetic resonance imaging guidance of radio frequency tumor ablation. Ann Biomed Eng (2002) 1.07
Low-carbohydrate/high-fat diet attenuates pressure overload-induced ventricular remodeling and dysfunction. J Card Fail (2008) 1.06
Therapy with cardiac contractility modulation electrical signals improves left ventricular function and remodeling in dogs with chronic heart failure. J Am Coll Cardiol (2007) 1.05
High intake of saturated fat, but not polyunsaturated fat, improves survival in heart failure despite persistent mitochondrial defects. Cardiovasc Res (2011) 1.05
Plasma proteome dynamics: analysis of lipoproteins and acute phase response proteins with 2H2O metabolic labeling. Mol Cell Proteomics (2012) 1.05
The antioxidant tempol attenuates pressure overload-induced cardiac hypertrophy and contractile dysfunction in mice fed a high-fructose diet. Am J Physiol Heart Circ Physiol (2008) 1.04
Deleterious effects of sugar and protective effects of starch on cardiac remodeling, contractile dysfunction, and mortality in response to pressure overload. Am J Physiol Heart Circ Physiol (2007) 1.03
Improved mitochondrial function with diet-induced increase in either docosahexaenoic acid or arachidonic acid in membrane phospholipids. PLoS One (2012) 1.03
Ranolazine combined with enalapril or metoprolol prevents progressive LV dysfunction and remodeling in dogs with moderate heart failure. Am J Physiol Heart Circ Physiol (2008) 1.03
Effects of exercise training and diet on lipid kinetics during free fatty acid-induced insulin resistance in older obese humans with impaired glucose tolerance. Am J Physiol Endocrinol Metab (2009) 1.01
Reverse changes in cardiac substrate oxidation in dogs recovering from heart failure. Am J Physiol Heart Circ Physiol (2008) 1.01
Impact of glucose-6-phosphate dehydrogenase deficiency on the pathophysiology of cardiovascular disease. Am J Physiol Heart Circ Physiol (2012) 1.00
Potential impact of carbohydrate and fat intake on pathological left ventricular hypertrophy. Cardiovasc Res (2006) 1.00
Assessing the reversibility of the anaplerotic reactions of the propionyl-CoA pathway in heart and liver. J Biol Chem (2003) 0.99
Fatty acid oxidation in cardiac and skeletal muscle mitochondria is unaffected by deletion of CD36. Arch Biochem Biophys (2007) 0.99
High-sugar diets increase cardiac dysfunction and mortality in hypertension compared to low-carbohydrate or high-starch diets. J Hypertens (2008) 0.99
Reduced synthesis of NO causes marked alterations in myocardial substrate metabolism in conscious dogs. Am J Physiol Endocrinol Metab (2002) 0.99
Multi-scale computational model of fuel homeostasis during exercise: effect of hormonal control. Ann Biomed Eng (2006) 0.99
Carnitine palmitoyl transferase-I inhibition is not associated with cardiac hypertrophy in rats fed a high-fat diet. Clin Exp Pharmacol Physiol (2007) 0.98
Drug-eluting polymer implants in cancer therapy. Expert Opin Drug Deliv (2008) 0.98
Regulation of lactate production at the onset of ischaemia is independent of mitochondrial NADH/NAD+: insights from in silico studies. J Physiol (2005) 0.97
Mechanistic model of myocardial energy metabolism under normal and ischemic conditions. Ann Biomed Eng (2002) 0.97
Dissociation between gene and protein expression of metabolic enzymes in a rodent model of heart failure. Eur J Heart Fail (2006) 0.97
Exogenous nitric oxide reduces glucose transporters translocation and lactate production in ischemic myocardium in vivo. Proc Natl Acad Sci U S A (2005) 0.96
Model of oxygen transport and metabolism predicts effect of hyperoxia on canine muscle oxygen uptake dynamics. J Appl Physiol (1985) (2007) 0.95
Regulation of myocardial substrate metabolism during increased energy expenditure: insights from computational studies. Am J Physiol Heart Circ Physiol (2006) 0.95
Rapid attenuation of circadian clock gene oscillations in the rat heart following ischemia-reperfusion. J Mol Cell Cardiol (2007) 0.95
MRI-guided thermal ablation therapy: model and parameter estimates to predict cell death from MR thermometry images. Ann Biomed Eng (2007) 0.95
Differential effects of heptanoate and hexanoate on myocardial citric acid cycle intermediates following ischemia-reperfusion. J Appl Physiol (1985) (2005) 0.94
Effects of adiponectin deficiency on structural and metabolic remodeling in mice subjected to pressure overload. Am J Physiol Heart Circ Physiol (2010) 0.94
Altered expression of the adenine nucleotide translocase isoforms and decreased ATP synthase activity in skeletal muscle mitochondria in heart failure. J Mol Cell Cardiol (2009) 0.93
Role of the malate-aspartate shuttle on the metabolic response to myocardial ischemia. J Theor Biol (2008) 0.92
Role of NADH/NAD+ transport activity and glycogen store on skeletal muscle energy metabolism during exercise: in silico studies. Am J Physiol Cell Physiol (2008) 0.92
Linking pulmonary oxygen uptake, muscle oxygen utilization and cellular metabolism during exercise. Ann Biomed Eng (2007) 0.92
Enhanced resistance to permeability transition in interfibrillar cardiac mitochondria in dogs: effects of aging and long-term aldosterone infusion. Am J Physiol Heart Circ Physiol (2012) 0.92
ω-3 Polyunsaturated fatty acids prevent pressure overload-induced ventricular dilation and decrease in mitochondrial enzymes despite no change in adiponectin. Lipids Health Dis (2010) 0.91
Chronic activation of peroxisome proliferator-activated receptor-alpha with fenofibrate prevents alterations in cardiac metabolic phenotype without changing the onset of decompensation in pacing-induced heart failure. J Pharmacol Exp Ther (2007) 0.91
Fatty acid oxidation and its impact on response of spontaneously hypertensive rat hearts to an adrenergic stress: benefits of a medium-chain fatty acid. Am J Physiol Heart Circ Physiol (2004) 0.90
Quantitative assessment of anaplerosis from propionate in pig heart in vivo. Am J Physiol Endocrinol Metab (2002) 0.90
Modeling oxygenation in venous blood and skeletal muscle in response to exercise using near-infrared spectroscopy. J Appl Physiol (1985) (2009) 0.90
Does junk food lead to heart failure? Importance of dietary macronutrient composition in hypertension. Hypertension (2009) 0.90
Robust experiment design for estimating myocardial beta adrenergic receptor concentration using PET. Med Phys (2007) 0.89
Modeling cellular metabolism and energetics in skeletal muscle: large-scale parameter estimation and sensitivity analysis. IEEE Trans Biomed Eng (2008) 0.89
Quantification of in vivo doxorubicin transport from PLGA millirods in thermoablated rat livers. J Control Release (2003) 0.89
Metabolic dynamics in skeletal muscle during acute reduction in blood flow and oxygen supply to mitochondria: in-silico studies using a multi-scale, top-down integrated model. PLoS One (2008) 0.88
Stromal interaction molecule 1 is essential for normal cardiac homeostasis through modulation of ER and mitochondrial function. Am J Physiol Heart Circ Physiol (2014) 0.88
Glucose 6-phosphate dehydrogenase deficiency increases redox stress and moderately accelerates the development of heart failure. Circ Heart Fail (2012) 0.88
Metabolic approaches to the treatment of ischemic heart disease: the clinicians' perspective. Heart Fail Rev (2002) 0.87
Partial inhibition of fatty acid oxidation increases regional contractile power and efficiency during demand-induced ischemia. Cardiovasc Res (2003) 0.87
Alterations in internal elastic lamina permeability as a function of age and anatomical site precede lesion development in apolipoprotein E-null mice. Circ Res (2005) 0.86
Hemoglobin and myoglobin contributions to skeletal muscle oxygenation in response to exercise. Adv Exp Med Biol (2011) 0.86
High-sugar intake does not exacerbate metabolic abnormalities or cardiac dysfunction in genetic cardiomyopathy. Nutrition (2012) 0.86