PubRank

James K V Willson

Author PubWeight™ 181.41‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The consensus coding sequences of human breast and colorectal cancers. Science 2006 60.02
2 The genomic landscapes of human breast and colorectal cancers. Science 2007 38.12
3 High frequency of mutations of the PIK3CA gene in human cancers. Science 2004 27.94
4 Mutational analysis of the tyrosine kinome in colorectal cancers. Science 2003 5.43
5 Colorectal cancer: mutations in a signalling pathway. Nature 2005 5.42
6 Glucose deprivation contributes to the development of KRAS pathway mutations in tumor cells. Science 2009 5.31
7 Mutational analysis of the tyrosine phosphatome in colorectal cancers. Science 2004 4.67
8 Integrated analysis of homozygous deletions, focal amplifications, and sequence alterations in breast and colorectal cancers. Proc Natl Acad Sci U S A 2008 4.13
9 Detection in fecal DNA of colon cancer-specific methylation of the nonexpressed vimentin gene. J Natl Cancer Inst 2005 3.73
10 Prevalence of somatic alterations in the colorectal cancer cell genome. Proc Natl Acad Sci U S A 2002 3.25
11 Silence of chromosomal amplifications in colon cancer. Cancer Res 2002 2.58
12 The noncoding RNA, miR-126, suppresses the growth of neoplastic cells by targeting phosphatidylinositol 3-kinase signaling and is frequently lost in colon cancers. Genes Chromosomes Cancer 2008 2.52
13 Three classes of genes mutated in colorectal cancers with chromosomal instability. Cancer Res 2004 2.51
14 15-Hydroxyprostaglandin dehydrogenase, a COX-2 oncogene antagonist, is a TGF-beta-induced suppressor of human gastrointestinal cancers. Proc Natl Acad Sci U S A 2004 2.42
15 SLC5A8, a sodium transporter, is a tumor suppressor gene silenced by methylation in human colon aberrant crypt foci and cancers. Proc Natl Acad Sci U S A 2003 2.01
16 Evidence of selection for clones having genetic inactivation of the activin A type II receptor (ACVR2) gene in gastrointestinal cancers. Cancer Res 2003 1.58
17 Focus on colon cancer. Cancer Cell 2002 1.54
18 Inactivating germ-line and somatic mutations in polypeptide N-acetylgalactosaminyltransferase 12 in human colon cancers. Proc Natl Acad Sci U S A 2009 1.51
19 HLTF gene silencing in human colon cancer. Proc Natl Acad Sci U S A 2002 1.43
20 PMEPA1, a transforming growth factor-beta-induced marker of terminal colonocyte differentiation whose expression is maintained in primary and metastatic colon cancer. Cancer Res 2003 1.22
21 A novel mechanism of resistance to epidermal growth factor receptor antagonism in vivo. Cancer Res 2007 1.13
22 Colon carcinoma cells harboring PIK3CA mutations display resistance to growth factor deprivation induced apoptosis. Mol Cancer Ther 2007 1.11
23 Blockade of EGFR and ErbB2 by the novel dual EGFR and ErbB2 tyrosine kinase inhibitor GW572016 sensitizes human colon carcinoma GEO cells to apoptosis. Cancer Res 2006 1.11
24 TGF-beta-induced nuclear localization of Smad2 and Smad3 in Smad4 null cancer cell lines. Oncogene 2003 1.09
25 The role of transforming growth factor alpha in determining growth factor independence. Cancer Res 2003 1.01
26 Mutational inactivation of TGFBR2 in microsatellite unstable colon cancer arises from the cooperation of genomic instability and the clonal outgrowth of transforming growth factor beta resistant cells. Genes Chromosomes Cancer 2008 0.97
27 Autocrine heregulin generates growth factor independence and blocks apoptosis in colon cancer cells. Oncogene 2002 0.96
28 Reorganization of ErbB family and cell survival signaling after Knock-down of ErbB2 in colon cancer cells. J Biol Chem 2005 0.84
29 Colon cancer secreted protein-2 (CCSP-2), a novel candidate serological marker of colon neoplasia. Oncogene 2005 0.82
30 Ugene, a newly identified protein that is commonly overexpressed in cancer and binds uracil DNA glycosylase. Cancer Res 2008 0.79
31 Chromosomal autonomy of hMLH1 methylation in colon cancer. Oncogene 2002 0.78