Published in J Korean Med Sci on August 01, 2005
Estimation of total, protein-bound, and nonprotein sulfhydryl groups in tissue with Ellman's reagent. Anal Biochem (1968) 11.64
Bilirubin is an antioxidant of possible physiological importance. Science (1987) 11.26
A simplified method for the quantitative assay of small amounts of protein in biologic material. Anal Biochem (1973) 10.11
The heme oxygenase system: a regulator of second messenger gases. Annu Rev Pharmacol Toxicol (1997) 7.50
Heme oxygenase: function, multiplicity, regulatory mechanisms, and clinical applications. FASEB J (1988) 5.24
Heme oxygenase is the major 32-kDa stress protein induced in human skin fibroblasts by UVA radiation, hydrogen peroxide, and sodium arsenite. Proc Natl Acad Sci U S A (1989) 4.57
Heme oxygenase: colors of defense against cellular stress. Am J Physiol Lung Cell Mol Physiol (2000) 2.99
The heme synthesis and degradation pathways: role in oxidant sensitivity. Heme oxygenase has both pro- and antioxidant properties. Free Radic Biol Med (2000) 2.61
Induction of heme oxygenase: a general response to oxidant stress in cultured mammalian cells. Cancer Res (1991) 2.30
Cellular glutathione and thiols metabolism. Biochem Pharmacol (2002) 2.14
Heme oxygenase 1 mediates an adaptive response to oxidative stress in human skin fibroblasts. Proc Natl Acad Sci U S A (1994) 2.13
Factors predicting severe radiation pneumonitis in patients receiving definitive chemoradiation for lung cancer. Int J Radiat Oncol Biol Phys (2000) 1.79
Dose-dependent induction of transforming growth factor beta (TGF-beta) in the lung tissue of fibrosis-prone mice after thoracic irradiation. Int J Radiat Oncol Biol Phys (2000) 1.72
Regulation of redox glutathione levels and gene transcription in lung inflammation: therapeutic approaches. Free Radic Biol Med (2000) 1.61
Dynamics of haem oxygenase-1 expression and bilirubin production in cellular protection against oxidative stress. Biochem J (2000) 1.38
The human 32-kDa stress protein induced by exposure to arsenite and cadmium ions is heme oxygenase. FEBS Lett (1989) 1.34
Cytokine induction of haem oxygenase mRNA in mouse liver. Interleukin 1 transcriptionally activates the haem oxygenase gene. Biochem J (1993) 1.33
Thiols in cellular redox signalling and control. Curr Med Chem (2001) 1.26
The physical parameters and molecular events associated with radiation-induced lung toxicity. Semin Radiat Oncol (2000) 1.20
Prematurely evoked synthesis and induction of delta-aminolevulinate synthetase in neonatal liver. Evidence for metal ion repression of enzyme formation. J Biol Chem (1978) 1.19
Endogenous glutathione levels modulate both constitutive and UVA radiation/hydrogen peroxide inducible expression of the human heme oxygenase gene. Carcinogenesis (1992) 1.17
Alterations in the expression of chemokine mRNA levels in fibrosis-resistant and -sensitive mice after thoracic irradiation. Exp Lung Res (1998) 0.97
The role of heme oxygenase-1 in pulmonary fibrosis. Am J Respir Cell Mol Biol (2003) 0.91
Heme oxygenase isoform expression in cellular and antibody-mediated models of acute inflammation in the rat. J Pathol (2000) 0.87
Hyperoxic regulation of lung heme oxygenase in neonatal rats. Pediatr Res (1996) 0.86
Induction of heme oxygenase 1 in radiation nephropathy: role of angiotensin II. Radiat Res (2001) 0.82
Changes of glutathione and protein bound SH-groups concentration in rat adrenals under acute and repeated stress. Endocrinol Exp (1982) 0.82
Whole-body X-irradiation induces acute and transient expression of heme oxygenase-1 in rat liver. J Radiat Res (2002) 0.80
Long-term effect of hypophysectomy on various fractions of sulfhydryl groups in thyroid, adrenal and some other organs in rats. Endocrinol Exp (1985) 0.80
[Effect of x-ray irradiation on the activity of key enzymes in heme biosynthesis and breakdown in the rat liver]. Biull Eksp Biol Med (1985) 0.77
A study on the incidence of ABL gene deletion on derivative chromosome 9 in chronic myelogenous leukemia by interphase fluorescence in situ hybridization and its association with disease progression. Genes Chromosomes Cancer (2003) 2.01
Immunostimulating effects of acidic polysaccharides extract of Panax ginseng on macrophage function. Immunopharmacol Immunotoxicol (2002) 1.27
The immunomodulator ginsan induces resistance to experimental sepsis by inhibiting Toll-like receptor-mediated inflammatory signals. Eur J Immunol (2006) 1.20
Natural derivatives of curcumin attenuate the Wnt/beta-catenin pathway through down-regulation of the transcriptional coactivator p300. Biochem Biophys Res Commun (2008) 1.20
Protection of Staphylococcus aureus-infected septic mice by suppression of early acute inflammation and enhanced antimicrobial activity by ginsan. FEMS Immunol Med Microbiol (2006) 1.17
Modulation of radiation-induced disturbances of antioxidant defense systems by ginsan. Evid Based Complement Alternat Med (2005) 1.11
An effective strategy for increasing the radiosensitivity of Human lung Cancer cells by blocking Nrf2-dependent antioxidant responses. Free Radic Biol Med (2012) 1.06
Induction of secretory and tumoricidal activities in peritoneal macrophages by ginsan. Int Immunopharmacol (2002) 1.05
Radioprotective effects of ginsan, an immunomodulator. Radiat Res (2003) 1.04
Protective action of the immunomodulator ginsan against carbon tetrachloride-induced liver injury via control of oxidative stress and the inflammatory response. Toxicol Appl Pharmacol (2009) 1.03
Sustained expression of NADPH oxidase 4 by p38 MAPK-Akt signaling potentiates radiation-induced differentiation of lung fibroblasts. J Mol Med (Berl) (2010) 0.99
An acidic polysaccharide of Panax ginseng ameliorates experimental autoimmune encephalomyelitis and induces regulatory T cells. Immunol Lett (2011) 0.94
Ginsan improved Th1 immune response inhibited by gamma radiation. Arch Pharm Res (2005) 0.92
Immunomodulatory activity of ginsan, a polysaccharide of panax ginseng, on dendritic cells. Korean J Physiol Pharmacol (2009) 0.92
N,N-dimethyl phytosphingosine induces caspase-8-dependent cytochrome c release and apoptosis through ROS generation in human leukemia cells. Toxicol Appl Pharmacol (2009) 0.92
Effect of gamma radiation on cytokine expression and cytokine-receptor mediated STAT activation. Int J Radiat Biol (2006) 0.91
Acidic polysaccharide of Panax ginseng as a defense against small intestinal damage by whole-body gamma irradiation of mice. Acta Histochem (2009) 0.90
Antimutagenic effect of polysaccharide ginsan extracted from Panax ginseng. Food Chem Toxicol (2005) 0.88
Nimesulide, a selective COX-2 inhibitor, acts synergistically with ionizing radiation against A549 human lung cancer cells through the activation of caspase-8 and caspase-3. Int J Oncol (2009) 0.86
Suppressive effects of ginsan on the development of allergic reaction in murine asthmatic model. Int Arch Allergy Immunol (2009) 0.86
Photodynamic therapy-mediated DC immunotherapy is highly effective for the inhibition of established solid tumors. Cancer Lett (2012) 0.86
Effects of polysaccharide ginsan from Panax ginseng on liver function. Arch Pharm Res (2004) 0.85
Gamma irradiation-reduced IFN-gamma expression, STAT1 signals, and cell-mediated immunity. J Biochem Mol Biol (2002) 0.84
The inhibitory effect of ginsan on TGF-β mediated fibrotic process. J Cell Physiol (2011) 0.83
Ginsan enhances humoral antibody response to orally delivered antigen. Immune Netw (2010) 0.82
Isoreserpine promotes beta-catenin degradation via Siah-1 up-regulation in HCT116 colon cancer cells. Biochem Biophys Res Commun (2009) 0.82
The human-animal interface and zoonotic threats: the Russian Federation approach. Biosecur Bioterror (2013) 0.80
Acriflavine enhances radiosensitivity of colon cancer cells through endoplasmic reticulum stress-mediated apoptosis. Int J Biochem Cell Biol (2012) 0.79
Low-dose γ-radiation inhibits IL-1β-induced dedifferentiation and inflammation of articular chondrocytes via blockage of catenin signaling. IUBMB Life (2014) 0.79
Immunomodulatory activity of protein-bound polysaccharide extracted from Chelidonium majus. Arch Pharm Res (2002) 0.78
Tissue-specific changes in heme oxygenase activity and level of nonprotein thiols in C57Bl/6 mice after whole-body gamma-irradiation. Bull Exp Biol Med (2005) 0.77
Radiation protective effect of an extract from Chelidonium majus. Int J Hematol (2003) 0.77
TGF-β signaling plays an important role in resisting γ-irradiation. Exp Cell Res (2012) 0.77
Inhibition of type III TGF-β receptor aggravates lung fibrotic process. Biomed Pharmacother (2010) 0.77
IM-412 inhibits transforming growth factor beta-induced fibroblast differentiation in human lung fibroblast cells. Biochem Biophys Res Commun (2010) 0.77
Myosin-primed tolerogenic dendritic cells ameliorate experimental autoimmune myocarditis. Cardiovasc Res (2013) 0.77
Enhancement of radiosensitivity by combined ceramide and dimethylsphingosine treatment in lung cancer cells. Exp Mol Med (2004) 0.77
Overexpression of alpha1-protease inhibitor and galectin-1 in radiation-induced early phase of pulmonary fibrosis. Cancer Res Treat (2006) 0.75
N-acetylphytosphingosine enhances the radiosensitivity of lung cancer cell line NCI-H460. Mol Cells (2008) 0.75