Published in Comb Chem High Throughput Screen on June 01, 2005
Increasing the Content of High-Content Screening: An Overview. J Biomol Screen (2014) 1.36
Automated tracking of gene expression in individual cells and cell compartments. J R Soc Interface (2006) 1.30
Differential CCR7 Targeting in Dendritic Cells by Three Naturally Occurring CC-Chemokines. Front Immunol (2016) 0.77
C-terminal engineering of CXCL12 and CCL5 chemokines: functional characterization by electrophysiological recordings. PLoS One (2014) 0.75
Biofilm formation by Pseudomonas aeruginosa wild type, flagella and type IV pili mutants. Mol Microbiol (2003) 5.31
Inhibition of quorum sensing in Pseudomonas aeruginosa biofilm bacteria by a halogenated furanone compound. Microbiology (2002) 3.37
Molecular mechanism of 7TM receptor activation--a global toggle switch model. Annu Rev Pharmacol Toxicol (2006) 3.33
Molecular analysis of rugosity in a Vibrio cholerae O1 El Tor phase variant. Mol Microbiol (2004) 2.66
Ligand binding and micro-switches in 7TM receptor structures. Trends Pharmacol Sci (2009) 2.33
Stratified growth in Pseudomonas aeruginosa biofilms. Appl Environ Microbiol (2004) 2.16
International Union of Basic and Clinical Pharmacology. [corrected]. LXXXIX. Update on the extended family of chemokine receptors and introducing a new nomenclature for atypical chemokine receptors. Pharmacol Rev (2013) 2.11
A simple technique for reducing edge effect in cell-based assays. J Biomol Screen (2003) 1.86
Severe inbreeding depression in a wild wolf (Canis lupus) population. Biol Lett (2005) 1.73
The exopolysaccharide matrix modulates the interaction between 3D architecture and virulence of a mixed-species oral biofilm. PLoS Pathog (2012) 1.72
Metabolic commensalism and competition in a two-species microbial consortium. Appl Environ Microbiol (2002) 1.47
2-Oleoyl glycerol is a GPR119 agonist and signals GLP-1 release in humans. J Clin Endocrinol Metab (2011) 1.44
Emerging classes of protein-protein interaction inhibitors and new tools for their development. Curr Opin Chem Biol (2004) 1.38
Syntheses and antiproliferative evaluation of oxyphenisatin derivatives. Bioorg Med Chem Lett (2007) 1.22
The carboxyl terminus of human cytomegalovirus-encoded 7 transmembrane receptor US28 camouflages agonism by mediating constitutive endocytosis. J Biol Chem (2003) 1.20
GPR119 as a fat sensor. Trends Pharmacol Sci (2012) 1.20
AMD3465, a monomacrocyclic CXCR4 antagonist and potent HIV entry inhibitor. Biochem Pharmacol (2005) 1.11
Epstein-Barr virus-encoded BILF1 is a constitutively active G protein-coupled receptor. J Virol (2005) 1.10
Histological grading of invasive breast carcinoma--a simplification of existing methods in a large conservation series with long-term follow-up. Histopathology (2009) 1.06
The Nature Index: a general framework for synthesizing knowledge on the state of biodiversity. PLoS One (2011) 1.06
Similar activation of signal transduction pathways by the herpesvirus-encoded chemokine receptors US28 and ORF74. Virology (2004) 1.06
The angiotensin type 1 receptor activates extracellular signal-regulated kinases 1 and 2 by G protein-dependent and -independent pathways in cardiac myocytes and langendorff-perfused hearts. Basic Clin Pharmacol Toxicol (2007) 1.00
Positive versus negative modulation of different endogenous chemokines for CC-chemokine receptor 1 by small molecule agonists through allosteric versus orthosteric binding. J Biol Chem (2008) 0.99
Allosteric and orthosteric sites in CC chemokine receptor (CCR5), a chimeric receptor approach. J Biol Chem (2011) 0.98
Structural motifs of importance for the constitutive activity of the orphan 7TM receptor EBI2: analysis of receptor activation in the absence of an agonist. Mol Pharmacol (2008) 0.97
Functional analysis of the murine cytomegalovirus chemokine receptor homologue M33: ablation of constitutive signaling is associated with an attenuated phenotype in vivo. J Virol (2007) 0.97
A highly conserved glycine within linker I and the extreme C terminus of G protein alpha subunits interact cooperatively in switching G protein-coupled receptor-to-effector specificity. J Pharmacol Exp Ther (2004) 0.95
Biased and constitutive signaling in the CC-chemokine receptor CCR5 by manipulating the interface between transmembrane helices 6 and 7. J Biol Chem (2013) 0.95
Identification of a novel site within G protein alpha subunits important for specificity of receptor-G protein interaction. Mol Pharmacol (2004) 0.93
Ligand modulation of the Epstein-Barr virus-induced seven-transmembrane receptor EBI2: identification of a potent and efficacious inverse agonist. J Biol Chem (2011) 0.92
Differential extracellular signal-regulated kinases 1 and 2 activation by the angiotensin type 1 receptor supports distinct phenotypes of cardiac myocytes. Basic Clin Pharmacol Toxicol (2007) 0.92
Mutations at the CXCR4 interaction sites for AMD3100 influence anti-CXCR4 antibody binding and HIV-1 entry. FEBS Lett (2003) 0.90
Kaposi sarcoma-associated herpes virus targets the lymphotactin receptor with both a broad spectrum antagonist vCCL2 and a highly selective and potent agonist vCCL3. J Biol Chem (2007) 0.89
An analytical tool-box for comprehensive biochemical, structural and transcriptome evaluation of oral biofilms mediated by mutans streptococci. J Vis Exp (2011) 0.89
Partial functional complementation between human and mouse cytomegalovirus chemokine receptor homologues. J Virol (2011) 0.89
Molecular characterization of oxysterol binding to the Epstein-Barr virus-induced gene 2 (GPR183). J Biol Chem (2012) 0.88
Exendin-4, but not dipeptidyl peptidase IV inhibition, increases small intestinal mass in GK rats. Am J Physiol Gastrointest Liver Physiol (2007) 0.88
Molecular interaction of a potent nonpeptide agonist with the chemokine receptor CCR8. Mol Pharmacol (2007) 0.88
Prohormone convertase 1/3 is essential for processing of the glucose-dependent insulinotropic polypeptide precursor. J Biol Chem (2006) 0.86
Oxysterol-EBI2 signaling in immune regulation and viral infection. Eur J Immunol (2014) 0.84
Virally encoded chemokines and chemokine receptors in the role of viral infections. Contrib Microbiol (2003) 0.84
Identification of common mechanisms by which human and mouse cytomegalovirus seven-transmembrane receptor homologues contribute to in vivo phenotypes in a mouse model. J Virol (2013) 0.83
GIP-(3-42) does not antagonize insulinotropic effects of GIP at physiological concentrations. Am J Physiol Endocrinol Metab (2006) 0.82
Modulation in selectivity and allosteric properties of small-molecule ligands for CC-chemokine receptors. J Med Chem (2012) 0.82
Identification and characterization of small molecule modulators of the Epstein-Barr virus-induced gene 2 (EBI2) receptor. J Med Chem (2014) 0.82
Small molecule antagonism of oxysterol-induced Epstein-Barr virus induced gene 2 (EBI2) activation. FEBS Open Bio (2013) 0.82
Identification of Akt pathway inhibitors using redistribution screening on the FLIPR and the IN Cell 3000 analyzer. J Biomol Screen (2005) 0.82
Porcine glucagon-like peptide-2: structure, signaling, metabolism and effects. Regul Pept (2007) 0.81
A complex multilevel attack on Pseudomonas aeruginosa algT/U expression and algT/U activity results in the loss of alginate production. Gene (2011) 0.81
Chapter 8. Activation mechanisms of chemokine receptors. Methods Enzymol (2009) 0.81
Nuclear export inhibitors and kinase inhibitors identified using a MAPK-activated protein kinase 2 redistribution screen. Assay Drug Dev Technol (2004) 0.81
Protein translocation assays: key tools for accessing new biological information with high-throughput microscopy. Methods Enzymol (2006) 0.80
Rational design of conformationally constrained cyclopentapeptide antagonists for C-x-C chemokine receptor 4 (CXCR4). J Med Chem (2012) 0.79
The E92K melanocortin 1 receptor mutant induces cAMP production and arrestin recruitment but not ERK activity indicating biased constitutive signaling. PLoS One (2011) 0.79
Multistep continuous-flow synthesis in medicinal chemistry: discovery and preliminary structure-activity relationships of CCR8 ligands. Chemistry (2013) 0.78
Microbiological exploitation of the chemokine system. Microbes Infect (2003) 0.78
A simple cell-based HTS assay system to screen for inhibitors of p53-Hdm2 protein-protein interactions. Assay Drug Dev Technol (2006) 0.78
Structure-activity relationship studies of the aromatic positions in cyclopentapeptide CXCR4 antagonists. Org Biomol Chem (2013) 0.78
Structure-activity relationships and identification of optmized CC-chemokine receptor CCR1, 5, and 8 metal-ion chelators. J Chem Inf Model (2013) 0.77
Modest human immunodeficiency virus coreceptor function of CXCR3 is strongly enhanced by mimicking the CXCR4 ligand binding pocket in the CXCR3 receptor. J Virol (2007) 0.77
Extracellular disulfide bridges serve different purposes in two homologous chemokine receptors, CCR1 and CCR5. Mol Pharmacol (2013) 0.77
High content translocation assays for pathway profiling. Methods Mol Biol (2007) 0.75
Identification of RAS-mitogen-activated protein kinase signaling pathway modulators in an ERF1 redistribution screen. J Biomol Screen (2006) 0.75