PubRank

Christine Brideau

Author PubWeight™ 14.53‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Statistical and graphical methods for quality control determination of high-throughput screening data. J Biomol Screen 2003 1.27
2 Substituted phenanthrene imidazoles as potent, selective, and orally active mPGES-1 inhibitors. Bioorg Med Chem Lett 2007 1.05
3 Substituted coumarins as potent 5-lipoxygenase inhibitors. Bioorg Med Chem Lett 2006 0.93
4 Discovery of disubstituted phenanthrene imidazoles as potent, selective and orally active mPGES-1 inhibitors. Bioorg Med Chem Lett 2009 0.93
5 Pharmacological characterization of a selective COX-2 inhibitor MF-tricyclic, [3-(3,4-difluorophenyl)-4-(4-(methylsulfonyl)phenyl)-2-(5H)-furanone], in multiple preclinical species. Eur J Pharmacol 2007 0.92
6 In vitro effects and in vivo efficacy of a novel cyclooxygenase-2 inhibitor in dogs with experimentally induced synovitis. Am J Vet Res 2004 0.87
7 Discovery of L-791,943: a potent, selective, non emetic and orally active phosphodiesterase-4 inhibitor. Bioorg Med Chem Lett 2002 0.82
8 Discovery of novel P2Y14 agonist and antagonist using conventional and nonconventional methods. J Biomol Screen 2011 0.82
9 Substituted 4-(2,2-diphenylethyl)pyridine-N-oxides as phosphodiesterase-4 inhibitors: SAR study directed toward the improvement of pharmacokinetic parameters. Bioorg Med Chem Lett 2002 0.81
10 Substituted 2,2-bisaryl-bicycloheptanes as novel and potent inhibitors of 5-lipoxygenase activating protein. Bioorg Med Chem Lett 2008 0.79
11 Trisubstituted ureas as potent and selective mPGES-1 inhibitors. Bioorg Med Chem Lett 2011 0.79
12 3,4-Diaryl-5-hydroxyfuranones: highly selective inhibitors of cyclooxygenase-2 with aqueous solubility. Bioorg Med Chem Lett 2003 0.78
13 Pyridazinones as selective cyclooxygenase-2 inhibitors. Bioorg Med Chem Lett 2003 0.78
14 Substituted aminopyridines as potent and selective phosphodiesterase-4 inhibitors. Bioorg Med Chem Lett 2003 0.77
15 Biarylimidazoles as inhibitors of microsomal prostaglandin E2 synthase-1. Bioorg Med Chem Lett 2010 0.77
16 Identification of an indole series of prostaglandin D2 receptor antagonists. Bioorg Med Chem Lett 2006 0.75
17 An automated multistep high-throughput screening assay for the identification of lead inhibitors of the inducible enzyme mPGES-1. J Biomol Screen 2005 0.75
18 Discovery of a potent and selective COX-2 inhibitor in the alkoxy lactone series with optimized metabolic profile. Bioorg Med Chem Lett 2002 0.75
19 In vitro effects and in vivo efficacy of a novel cyclooxygenase-2 inhibitor in cats with lipopolysaccharide-induced pyrexia. Am J Vet Res 2005 0.75