Published in Pharmacogenomics J on January 01, 2005
Impact of common genetic variation on response to simvastatin therapy among 18 705 participants in the Heart Protection Study. Eur Heart J (2012) 1.75
Genetic variation in MDR1, LPL and eNOS genes and the response to atorvastatin treatment in ischemic stroke. Hum Genet (2012) 1.42
Combined influence of LDLR and HMGCR sequence variation on lipid-lowering response to simvastatin. Arterioscler Thromb Vasc Biol (2010) 1.19
Pharmacogenetic predictors of statin-mediated low-density lipoprotein cholesterol reduction and dose response. Circ Cardiovasc Genet (2008) 1.17
Genome-wide association study of genetic determinants of LDL-c response to atorvastatin therapy: importance of Lp(a). J Lipid Res (2012) 1.17
Cytochrome P450 2C8 pharmacogenetics: a review of clinical studies. Pharmacogenomics (2009) 1.15
Coordinately regulated alternative splicing of genes involved in cholesterol biosynthesis and uptake. PLoS One (2011) 1.14
Application of a Physiologically Based Pharmacokinetic Model to Predict OATP1B1-Related Variability in Pharmacodynamics of Rosuvastatin. CPT Pharmacometrics Syst Pharmacol (2014) 1.05
Systems-based approaches to cardiovascular disease. Nat Rev Cardiol (2012) 1.04
Lack of association between SLCO1B1 polymorphism and the lipid-lowering effects of atorvastatin and simvastatin in Chinese individuals. Eur J Clin Pharmacol (2012) 0.99
Regulation of apoAI processing by procollagen C-proteinase enhancer-2 and bone morphogenetic protein-1. J Lipid Res (2009) 0.95
Lack of effect of genetic polymorphisms of SLCO1B1 on the lipid-lowering response to pitavastatin in Chinese patients. Acta Pharmacol Sin (2010) 0.92
Pharmacogenetics of OATP transporters reveals that SLCO1B1 c.388A>G variant is determinant of increased atorvastatin response. Int J Mol Sci (2011) 0.91
PharmGKB very important pharmacogene: SLCO1B1. Pharmacogenet Genomics (2010) 0.90
Association between statin-induced creatine kinase elevation and genetic polymorphisms in SLCO1B1, ABCB1 and ABCG2. Eur J Clin Pharmacol (2014) 0.89
Genome-wide study of gene variants associated with differential cardiovascular event reduction by pravastatin therapy. PLoS One (2012) 0.84
Hypertension and aging. Ageing Res Rev (2016) 0.84
Disruption of the murine procollagen C-proteinase enhancer 2 gene causes accumulation of pro-apoA-I and increased HDL levels. J Lipid Res (2011) 0.83
Statin pharmacogenomics: pursuing biomarkers for predicting clinical outcomes. Discov Med (2013) 0.83
The Making of a CYP3A Biomarker Panel for Guiding Drug Therapy. J Pers Med (2012) 0.83
PharmGKB: very important pharmacogene--HMGCR. Pharmacogenet Genomics (2011) 0.82
To replicate or not to replicate: the case of pharmacogenetic studies: Establishing validity of pharmacogenomic findings: from replication to triangulation. Circ Cardiovasc Genet (2013) 0.81
Pharmacogenetics of response to statins. Curr Atheroscler Rep (2007) 0.80
Non-synonymous polymorphisms in the human SLCO1B1 gene: an in vitro analysis of SNP c.1929A>C. Mol Genet Genomics (2007) 0.79
Common genetic variation in six lipid-related and statin-related genes, statin use and risk of incident nonfatal myocardial infarction and stroke. Pharmacogenet Genomics (2008) 0.79
Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol? Pharmacogenomics (2010) 0.79
Associations of ABCB1 and IL-10 genetic polymorphisms with sirolimus-induced dyslipidemia in renal transplant recipients. Transplantation (2012) 0.77
Apolipoprotein E mRNA expression in mononuclear cells from normolipidemic and hypercholesterolemic individuals treated with atorvastatin. Lipids Health Dis (2011) 0.77
Pharmacogenomics of statins: understanding susceptibility to adverse effects. Pharmgenomics Pers Med (2016) 0.75
Pharmacogenetics of cardiovascular drug therapy. Clin Cases Miner Bone Metab (2009) 0.75
[Pharmacogenomic Biomarkers for the Prediction of Statin Efficacy and Safety]. G Ital Arterioscler (2013) 0.75
Laboratory Medicine in the Clinical Decision Support for Treatment of Hypercholesterolemia: Pharmacogenetics of Statins. Clin Lab Med (2016) 0.75
A Robust and Powerful Set-Valued Approach to Rare Variant Association Analyses of Secondary Traits in Case-Control Sequencing Studies. Genetics (2016) 0.75
Pitavastatin: finding its place in therapy. Ther Adv Chronic Dis (2011) 0.75
Association of ABCB1 (C3435T) and ABCC1 (G2012T) Polymorphisms with Clinical Response to Atorvastatin in Iranian Patients with Primary Hyperlipidemia. Iran Biomed J (2016) 0.75
Pharmacogenetic Foundations of Therapeutic Efficacy and Adverse Events of Statins. Int J Mol Sci (2017) 0.75
CYP3A5 genotyping for assessing the efficacy of treatment with simvastatin and atorvastatin. Genet Mol Biol (2015) 0.75
Lipoprotein lipase HindIII polymorphism influences HDL-cholesterol levels in statin-treated patients with coronary artery disease. Wien Klin Wochenschr (2007) 0.75
The stress-activated protein kinase subfamily of c-Jun kinases. Nature (1994) 11.45
Raf-1 activates MAP kinase-kinase. Nature (1992) 7.05
Modulation of firefly luciferase stability and impact on studies of gene regulation. Gene (1991) 4.21
Acute immunologic pulmonary alveolitis. J Clin Invest (1974) 3.53
Intravascular activation of complement and acute lung injury. Dependency on neutrophils and toxic oxygen metabolites. J Clin Invest (1982) 3.49
Plasma fibronectin supports neuronal survival and reduces brain injury following transient focal cerebral ischemia but is not essential for skin-wound healing and hemostasis. Nat Med (2001) 3.01
Pharmacodynamics of fluconazole in a murine model of systemic candidiasis. Antimicrob Agents Chemother (1998) 2.59
Role of oxygen metabolites in immune complex injury of lung. J Immunol (1981) 2.39
PD98059 is an equipotent antagonist of the aryl hydrocarbon receptor and inhibitor of mitogen-activated protein kinase kinase. Mol Pharmacol (1998) 2.16
Identification of a full-length cDNA for an endogenous retrovirus of miniature swine. J Virol (1998) 2.10
In vivo damage of rat lungs by oxygen metabolites. J Clin Invest (1981) 2.10
Role of the scavenger receptor MARCO in alveolar macrophage binding of unopsonized environmental particles. J Exp Med (1999) 2.08
Cloning and expression of two human p70 S6 kinase polypeptides differing only at their amino termini. Mol Cell Biol (1991) 2.00
Is oral rice electrolyte solution superior to glucose electrolyte solution in infantile diarrhoea? Arch Dis Child (1982) 1.99
Detection of structural and trace metal changes in scalp hair of radiographers. Health Phys (1993) 1.94
C5a-induced expression of P-selectin in endothelial cells. J Clin Invest (1994) 1.93
Tumor necrosis factor participates in the pathogenesis of acute immune complex alveolitis in the rat. J Clin Invest (1989) 1.86
Monocyte chemoattractant protein-1 accelerates atherosclerosis in apolipoprotein E-deficient mice. Arterioscler Thromb Vasc Biol (1999) 1.86
Can acetate replace bicarbonate in oral rehydration solution for infantile diarrhoea? Arch Dis Child (1982) 1.81
Requirement and role of C5a in acute lung inflammatory injury in rats. J Clin Invest (1996) 1.77
Epidermal growth factor (EGF)-like repeats of human tenascin-C as ligands for EGF receptor. J Cell Biol (2001) 1.74
Mitogen-activated protein kinase/extracellular signal-regulated protein kinase activation by oncogenes, serum, and 12-O-tetradecanoylphorbol-13-acetate requires Raf and is necessary for transformation. J Biol Chem (1994) 1.74
Treating activated CD4+ T cells with either of two distinct DNA methyltransferase inhibitors, 5-azacytidine or procainamide, is sufficient to cause a lupus-like disease in syngeneic mice. J Clin Invest (1993) 1.64
Search for supersymmetry using final states with one lepton, jets, and missing transverse momentum with the ATLAS detector in √s=7 TeV pp collisions. Phys Rev Lett (2011) 1.60
Isolation from human serum of an inactivator of bacterial lipopolysaccharide. Am J Pathol (1977) 1.58
Phlebotomy overdraw in the neonatal intensive care nursery. Pediatrics (2000) 1.57
In search of a super solution: controlled trial of glycine-glucose oral rehydration solution in infantile diarrhoea. Acta Paediatr Scand (1984) 1.57
Endothelial cell killing by neutrophils. Synergistic interaction of oxygen products and proteases. Am J Pathol (1989) 1.55
The effect of inhaled nitric oxide therapy on bleeding time and platelet aggregation in neonates. J Pediatr (1998) 1.53
Measurement of the forward-backward charge asymmetry in top-quark pair production. Phys Rev Lett (2008) 1.53
Regulation of an epitope-tagged recombinant Rsk-1 S6 kinase by phorbol ester and erk/MAP kinase. Biochemistry (1993) 1.50
Suppression by superoxide dismutase of immune-complex--induced pulmonary alveolitis and dermal inflammation. Am J Pathol (1981) 1.50
Requirements for leukocyte adhesion molecules in nephrotoxic nephritis. J Clin Invest (1993) 1.49
Circadian regulation of bioluminescence in Gonyaulax involves translational control. Proc Natl Acad Sci U S A (1989) 1.46
In vitro and in vivo stimulation of rat neutrophils and alveolar macrophages by immune complexes. Production of O-2 and H2O2. Am J Pathol (1983) 1.46
Mechanism of drug-induced lupus. I. Cloned Th2 cells modified with DNA methylation inhibitors in vitro cause autoimmunity in vivo. J Immunol (1995) 1.45
Bedtime H2 blockers improve nocturnal gastric acid control in GERD patients on proton pump inhibitors. Aliment Pharmacol Ther (2001) 1.43
Neutrophil-dependent, oxygen-radical mediated lung injury associated with acute pancreatitis. Ann Surg (1989) 1.43
Observation of a centrality-dependent dijet asymmetry in lead-lead collisions at sqrt[S(NN)] =2.76 TeV with the ATLAS detector at the LHC. Phys Rev Lett (2010) 1.41
Oxygen radical dependent lung damage following thermal injury of rat skin. J Trauma (1983) 1.41
Quantitative morphometry of renal biopsies prior to cyclosporine in nephrotic syndrome. Pediatr Nephrol (1998) 1.41
Evidence for the role of oxygen radicals in acute nephrotoxic nephritis. Lab Invest (1984) 1.40
Measurement of dijet azimuthal decorrelations in pp collisions at sqrt(s)=7 TeV. Phys Rev Lett (2011) 1.39
Treatment of psoriasis with aminophylline. Int J Dermatol (1992) 1.39
Whole time domestic child labor in metropolitan city of Kolkata. Indian Pediatr (2008) 1.39
Fas ligation triggers apoptosis in macrophages but not endothelial cells. Eur J Immunol (1994) 1.39
Approval of SHO posts is rarely withdrawn but is often given for limited time. BMJ (1997) 1.38
Progression of somatic CTG repeat length heterogeneity in the blood cells of myotonic dystrophy patients. Hum Mol Genet (1998) 1.36
Characterization of matrix metalloproteinases produced by rat alveolar macrophages. Am J Respir Cell Mol Biol (1999) 1.36
Estrogen reduces atherosclerotic lesion development in apolipoprotein E-deficient mice. Proc Natl Acad Sci U S A (1996) 1.35
High throughput genotyping for the detection of a single nucleotide polymorphism in NAD(P)H quinone oxidoreductase (DT diaphorase) using TaqMan probes. Mol Pathol (1999) 1.35
Determination of the strange-quark density of the proton from ATLAS measurements of the W→ℓν and Z→ℓℓ cross sections. Phys Rev Lett (2012) 1.34
Suppression of immune complex-induced inflammation by the chemotactic factor inactivator. J Clin Invest (1977) 1.33
Search for new particles in two-jet final states in 7 TeV proton-proton collisions with the ATLAS detector at the LHC. Phys Rev Lett (2010) 1.32
Characterization of the expression of DMPK and SIX5 in the human eye and implications for pathogenesis in myotonic dystrophy. Hum Mol Genet (1999) 1.32
The requirement for serum complement in the detoxification of bacterial endotoxin. J Immunol (1972) 1.30
Protein degradation following treatment with hydrogen peroxide. Am J Pathol (1984) 1.30
Acute lung injury in rat caused by immunoglobulin A immune complexes. J Clin Invest (1984) 1.29
Observation of associated near-side and away-side long-range correlations in sqrt[s(NN)]=5.02 TeV proton-lead collisions with the ATLAS detector. Phys Rev Lett (2013) 1.27
Acute acid aspiration lung injury in the rat: biphasic pathogenesis. Anesth Analg (1989) 1.27
Role of stromelysin 1 and gelatinase B in experimental acute lung injury. Am J Respir Cell Mol Biol (2001) 1.25
Immune complex vasculitis with secondary ulcerative dermatitis in aged C57BL/6NNia mice. Vet Pathol (1994) 1.25
The role of neutrophils, oxidants, and proteases in the pathogenesis of acid pulmonary injury. Anesthesiology (1992) 1.24
Age-related decrease in stimulated glutamate release and vesicular glutamate transporters in APP/PS1 transgenic and wild-type mice. J Neurochem (2007) 1.23
Pancreatitis-induced acute lung injury. An ARDS model. Ann Surg (1988) 1.21
Role of oxygen radicals in phorbol myristate acetate-induced glomerular injury. Kidney Int (1985) 1.20
Glomerular inflammation induces resistance to tubular injury in the rat. A novel form of acquired, heme oxygenase-dependent resistance to renal injury. J Clin Invest (1996) 1.20
Search for dark matter candidates and large extra dimensions in events with a photon and missing transverse momentum in pp collision data at sqrt[s]=7 TeV with the ATLAS detector. Phys Rev Lett (2013) 1.19
Regulatory effects of endogenous protease inhibitors in acute lung inflammatory injury. J Immunol (1999) 1.19
Urban air particulate inhalation alters pulmonary function and induces pulmonary inflammation in a rodent model of chronic bronchitis. Inhal Toxicol (1999) 1.16
Genetics and physiology of the myotonic muscle disorders. N Engl J Med (1993) 1.16
Role of O2- in neutrophil recruitment into sites of dermal and pulmonary vasculitis. Free Radic Biol Med (1990) 1.15
Search for a supersymmetric partner to the top quark in final states with jets and missing transverse momentum at sqrt[s] = 7 TeV with the ATLAS detector. Phys Rev Lett (2012) 1.13
A hierarchical cascade activated by non-canonical Notch signaling and the mTOR-Rictor complex regulates neglect-induced death in mammalian cells. Cell Death Differ (2009) 1.13
Role of matrix metalloproteinases in models of macrophage-dependent acute lung injury. Evidence for alveolar macrophage as source of proteinases. Am J Respir Cell Mol Biol (1999) 1.13
cbl-3: a new mammalian cbl family protein. Oncogene (1999) 1.13
The role of tumor necrosis factor-alpha in the pathogenesis of aspiration pneumonitis in rats. Anesthesiology (1999) 1.12
Protective function of C6 in rabbits treated with bacterial endotoxin. J Immunol (1971) 1.10
Gender-based effects on methylprednisolone pharmacokinetics and pharmacodynamics. Clin Pharmacol Ther (1993) 1.10
Monocyte chemotaxis and activating factor production by keratinocytes in response to IFN-gamma. J Immunol (1991) 1.09
Measurement of the electron charge asymmetry in pp[over ]-->W+X-->enu+X events at sqrt[s]=1.96 TeV. Phys Rev Lett (2008) 1.09
Tubby-like protein 1 homozygous splice-site mutation causes early-onset severe retinal degeneration. Invest Ophthalmol Vis Sci (1999) 1.09
Evidence for the role of platelet-activating factor in immune complex vasculitis in the rat. J Clin Invest (1989) 1.09
The human GCAP1 and GCAP2 genes are arranged in a tail-to-tail array on the short arm of chromosome 6 (p21.1). Genomics (1997) 1.08
Cytotoxicity of tumor necrosis factor-alpha for human umbilical vein endothelial cells. Lab Invest (1989) 1.07
Oxygen radicals, inflammation, and tissue injury. Free Radic Biol Med (1988) 1.07
Search for tb resonances in proton-proton collisions at √s=7 TeV with the ATLAS detector. Phys Rev Lett (2012) 1.07
The role of metalloelastase in immune complex-induced acute lung injury. Am J Pathol (2001) 1.06
Cloning of the human SIX1 gene and its assignment to chromosome 14. Genomics (1996) 1.05
Cloning of the human platelet F11 receptor: a cell adhesion molecule member of the immunoglobulin superfamily involved in platelet aggregation. Blood (2000) 1.05
Search for a light Higgs boson decaying to long-lived weakly interacting particles in proton-proton collisions at sqrt[s] = 7 TeV with the ATLAS detector. Phys Rev Lett (2012) 1.05
Biology of disease. Newer concepts in the pathogenesis of immune complex-induced tissue injury. Lab Invest (1982) 1.04
In vivo suppression of immune complex-induced alveolitis by secretory leukoproteinase inhibitor and tissue inhibitor of metalloproteinases 2. Proc Natl Acad Sci U S A (1993) 1.04
Macrophage-derived cytokines amplify immune complex-triggered O2-. responses by rat alveolar macrophages. Am J Pathol (1988) 1.04
Search for large extra dimensions via single photon plus missing energy final states at sqrt s = 1.96 TeV. Phys Rev Lett (2008) 1.04
Clinicopathological significance of p16 gene expression in the surgical treatment of head and neck squamous cell carcinomas. J Clin Pathol (2002) 1.04
Role of calcium and beta-adrenergic system in control of parathyroid hormone secretion. Proc Soc Exp Biol Med (1976) 1.03
Immunologic vasculitis in beige mice with deficiency of leukocytic neutral protease. J Immunol (1979) 1.03
Association of immunological changes with clinical efficacy in atopic eczema patients treated with traditional Chinese herbal therapy (Zemaphyte). Int Arch Allergy Immunol (1996) 1.01
Perinatal risk factors for hepatoblastoma. Br J Cancer (2008) 1.01