PubRank

David T Denhardt

Author PubWeight™ 68.26‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Osteopontin, a key component of the hematopoietic stem cell niche and regulator of primitive hematopoietic progenitor cells. Blood 2005 4.17
2 Osteopontin: role in immune regulation and stress responses. Cytokine Growth Factor Rev 2008 3.06
3 Control of osteopontin signaling and function by post-translational phosphorylation and protein folding. J Cell Biochem 2007 1.90
4 An osteopontin-NADPH oxidase signaling cascade promotes pro-matrix metalloproteinase 9 activation in aortic mesenchymal cells. Circ Res 2006 1.88
5 Osteopontin modulates CD44-dependent chemotaxis of peritoneal macrophages through G-protein-coupled receptors: evidence of a role for an intracellular form of osteopontin. J Cell Physiol 2004 1.76
6 Osteopontin deficiency protects joints against destruction in anti-type II collagen antibody-induced arthritis in mice. Proc Natl Acad Sci U S A 2002 1.55
7 Thrombin-cleaved osteopontin regulates hemopoietic stem and progenitor cell functions through interactions with alpha9beta1 and alpha4beta1 integrins. Blood 2009 1.53
8 Cell type-specific post-translational modifications of mouse osteopontin are associated with different adhesive properties. J Biol Chem 2007 1.36
9 Unloading induces osteoblastic cell suppression and osteoclastic cell activation to lead to bone loss via sympathetic nervous system. J Biol Chem 2005 1.27
10 Enhanced cell surface CD44 variant (v6, v9) expression by osteopontin in breast cancer epithelial cells facilitates tumor cell migration: novel post-transcriptional, post-translational regulation. Clin Exp Metastasis 2006 1.26
11 Accelerated development of aging-associated and instability-induced osteoarthritis in osteopontin-deficient mice. Arthritis Rheum 2009 1.20
12 Osteopontin-deficient mice exhibit less inflammation, greater tissue damage, and impaired locomotor recovery from spinal cord injury compared with wild-type controls. J Neurosci 2007 1.19
13 Expression genomics of cervical cancer: molecular classification and prediction of radiotherapy response by DNA microarray. Clin Cancer Res 2003 1.19
14 Hypoxia upregulates osteopontin expression in NIH-3T3 cells via a Ras-activated enhancer. Oncogene 2005 1.10
15 Increased thalamic neurodegeneration following ischaemic cortical stroke in osteopontin-deficient mice. Brain 2006 1.09
16 Osteopontin regulates hindlimb-unloading-induced lymphoid organ atrophy and weight loss by modulating corticosteroid production. Proc Natl Acad Sci U S A 2007 1.07
17 Exacerbated tissue destruction in DSS-induced acute colitis of OPN-null mice is associated with downregulation of TNF-alpha expression and non-programmed cell death. J Cell Physiol 2006 1.06
18 Resistance to unloading-induced three-dimensional bone loss in osteopontin-deficient mice. J Bone Miner Res 2002 1.04
19 An osteopontin-integrin interaction plays a critical role in directing adipogenesis and osteogenesis by mesenchymal stem cells. Stem Cells 2014 1.00
20 Characterization of anti-osteopontin monoclonal antibodies: Binding sensitivity to post-translational modifications. J Cell Biochem 2007 1.00
21 Sympathetic control of bone mass regulated by osteopontin. Proc Natl Acad Sci U S A 2011 0.99
22 Rho-dependent Rho kinase activation increases CD44 surface expression and bone resorption in osteoclasts. J Biol Chem 2003 0.99
23 The cytokine osteopontin modulates the severity of rotavirus diarrhea. J Virol 2005 0.99
24 Osteopontin expression in osteoblasts and osteocytes during bone formation under mechanical stress in the calvarial suture in vivo. J Bone Miner Res 2003 0.98
25 Expression of a prometastatic splice variant of osteopontin, OPNC, in human pancreatic ductal adenocarcinoma. Surgery 2009 0.98
26 Induction of osteopontin expression by nicotine and cigarette smoke in the pancreas and pancreatic ductal adenocarcinoma cells. Int J Cancer 2009 0.98
27 Osteopontin deficiency and aging on nanomechanics of mouse bone. J Biomed Mater Res A 2007 0.97
28 Osteopontin regulates development and function of invariant natural killer T cells. Proc Natl Acad Sci U S A 2008 0.97
29 Osteopontin deficiency induces parathyroid hormone enhancement of cortical bone formation. Endocrinology 2003 0.96
30 Regulation of collagenase-3 and osteocalcin gene expression by collagen and osteopontin in differentiating MC3T3-E1 cells. J Biol Chem 2002 0.96
31 Increased expression of the remodeling- and tumorigenic-associated factor osteopontin in pyramidal neurons of the Alzheimer's disease brain. Curr Alzheimer Res 2007 0.95
32 Corneal wound healing in an osteopontin-deficient mouse. Invest Ophthalmol Vis Sci 2008 0.95
33 Osteopontin is required for mechanical stress-dependent signals to bone marrow cells. J Endocrinol 2007 0.95
34 Osteopontin is associated with nuclear factor kappaB gene expression during tail-suspension-induced bone loss. Exp Cell Res 2006 0.95
35 Involvement of osteopontin in the matrix-degrading and proangiogenic changes mediated by nicotine in pancreatic cancer cells. J Gastrointest Surg 2010 0.92
36 Role of osteopontin in murine Lyme arthritis and host defense against Borrelia burgdorferi. Infect Immun 2002 0.92
37 Loss of osteopontin perturbs the epithelial-mesenchymal transition in an injured mouse lens epithelium. Lab Invest 2007 0.91
38 Plasma osteopontin modulates chronic restraint stress-induced thymus atrophy by regulating stress hormones: inhibition by an anti-osteopontin monoclonal antibody. J Immunol 2009 0.91
39 Osteopontin deficiency impairs wear debris-induced osteolysis via regulation of cytokine secretion from murine macrophages. Arthritis Rheum 2010 0.89
40 Osteopontin affects the persistence of beta-glucan-induced hepatic granuloma formation and tissue injury through two distinct mechanisms. Int Immunol 2004 0.88
41 Induction of monocyte chemoattractant protein-1 by nicotine in pancreatic ductal adenocarcinoma cells: role of osteopontin. Surgery 2010 0.88
42 The role of osteopontin in tendon tissue remodeling after denervation-induced mechanical stress deprivation. Matrix Biol 2006 0.87
43 Osteopontin-deficiency suppresses growth of B16 melanoma cells implanted in bone and osteoclastogenesis in co-cultures. J Bone Miner Res 2004 0.87
44 Osteopontin deficiency suppresses high phosphate load-induced bone loss via specific modulation of osteoclasts. Endocrinology 2006 0.86
45 Osteopontin negatively regulates parathyroid hormone receptor signaling in osteoblasts. J Biol Chem 2008 0.86
46 Aprt/Opn double knockout mice: osteopontin is a modifier of kidney stone disease severity. Kidney Int 2005 0.85
47 Osteopontin participates in Th1-mediated host resistance against nonlethal malaria parasite Plasmodium chabaudi chabaudi infection in mice. Infect Immun 2006 0.84
48 Impaired angiogenic response in the corneas of mice lacking osteopontin. Invest Ophthalmol Vis Sci 2009 0.84
49 Osteopontin deficiency protects against aldosterone-induced inflammation, oxidative stress, and interstitial fibrosis in the kidney. Am J Physiol Renal Physiol 2011 0.84
50 Characterization of osteopontin expression and function after status epilepticus. Epilepsia 2008 0.83
51 Osteopontin aggravates experimental autoimmune uveoretinitis in mice. J Immunol 2007 0.83
52 Osteopontin is dispensable for protection against high load systemic fungal infection. Int Immunopharmacol 2008 0.82
53 Acetaminophen attenuates doxorubicin-induced cardiac fibrosis via osteopontin and GATA4 regulation: reduction of oxidant levels. J Cell Physiol 2013 0.82
54 Tissue inhibitor of metalloproteinases-1 stimulates gene expression in MDA-MB-435 human breast cancer cells by means of its ability to inhibit metalloproteinases. Breast Cancer Res Treat 2005 0.82
55 Osteopontin expression and function within the dorsal root ganglion. Neuroreport 2007 0.81
56 Osteopontin regulates interleukin-17 production in hepatitis. Cytokine 2012 0.80
57 Crystallographically engineered, hydrothermally crystallized hydroxyapatite films: an in vitro study of bioactivity. J Mater Sci Mater Med 2010 0.80
58 Effect of osteopontin on diarrhea duration and innate immunity in suckling mice infected with a murine rotavirus. Viral Immunol 2009 0.79
59 Prenatal detection of embryo resorption in osteopontin-deficient mice using serial noninvasive magnetic resonance microscopy. Pediatr Res 2004 0.79
60 Osteopontin expression during early cerebral ischemia-reperfusion in rats: enhanced expression in the right cortex is suppressed by acetaminophen. PLoS One 2011 0.79
61 OPN deficiency suppresses appearance of odontoclastic cells and resorption of the tooth root induced by experimental force application. J Cell Physiol 2008 0.78
62 Osteopontin traffic in hypoxic renal epithelial cells. Nephron Exp Nephrol 2003 0.78
63 Osteoclasts resorb protein-free mineral (Osteologic discs) efficiently in the absence of osteopontin. In Vivo 2005 0.76
64 Osteopontin deficiency enhances parathyroid hormone/ parathyroid hormone related peptide receptor (PPR) signaling-induced alteration in tooth formation and odontoblastic morphology. Tissue Cell 2011 0.75
65 Hindlimb-unloading suppresses B cell population in the bone marrow and peripheral circulation associated with OPN expression in circulating blood cells. J Bone Miner Metab 2014 0.75
66 Osteopontin deficiency enhances anabolic action of EP4 agonist at a sub-optimal dose in bone. J Endocrinol 2007 0.75