Richard H Myers

Author PubWeight™ 135.27‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet 2010 23.08
2 Generation of isogenic pluripotent stem cells differing exclusively at two early onset Parkinson point mutations. Cell 2011 6.56
3 Genomewide association study for susceptibility genes contributing to familial Parkinson disease. Hum Genet 2008 5.04
4 Retracted Genetic signatures of exceptional longevity in humans. Science 2010 4.33
5 Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database. PLoS Genet 2012 4.27
6 A genome-wide association study of pulmonary function measures in the Framingham Heart Study. PLoS Genet 2009 3.78
7 Genetic signatures of exceptional longevity in humans. PLoS One 2012 3.20
8 Meta-analysis of Parkinson's disease: identification of a novel locus, RIT2. Ann Neurol 2012 2.20
9 The Gly2019Ser mutation in LRRK2 is not fully penetrant in familial Parkinson's disease: the GenePD study. BMC Med 2008 2.10
10 A genome-wide scan for loci linked to plasma levels of glucose and HbA(1c) in a community-based sample of Caucasian pedigrees: The Framingham Offspring Study. Diabetes 2002 1.99
11 HD CAG repeat implicates a dominant property of huntingtin in mitochondrial energy metabolism. Hum Mol Genet 2005 1.96
12 Influence of heterozygosity for parkin mutation on onset age in familial Parkinson disease: the GenePD study. Arch Neurol 2006 1.94
13 A genome scan for modifiers of age at onset in Huntington disease: The HD MAPS study. Am J Hum Genet 2003 1.85
14 Quantitative-trait loci influencing body-mass index reside on chromosomes 7 and 13: the National Heart, Lung, and Blood Institute Family Heart Study. Am J Hum Genet 2001 1.59
15 Somatic expansion of the Huntington's disease CAG repeat in the brain is associated with an earlier age of disease onset. Hum Mol Genet 2009 1.51
16 Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction. Am J Respir Crit Care Med 2012 1.49
17 Genetic loci influencing lung function: a genome-wide scan in the Framingham Study. Am J Respir Crit Care Med 2002 1.47
18 Linkage of the cholesterol 7alpha-hydroxylase gene and low-density lipoprotein cholesterol conditional on apolipoprotein E association: the National Heart, Lung, and Blood Institute Family Heart Study. Chin Med J (Engl) 2005 1.42
19 Huntington CAG repeat size does not modify onset age in familial Parkinson's disease: the GenePD study. Mov Disord 2008 1.41
20 Genomewide linkage analysis to presbycusis in the Framingham Heart Study. Arch Otolaryngol Head Neck Surg 2003 1.38
21 Genetic variability of adult body mass index: a longitudinal assessment in framingham families. Obes Res 2002 1.34
22 Retraction. Science 2011 1.32
23 Genetic background modifies nuclear mutant huntingtin accumulation and HD CAG repeat instability in Huntington's disease knock-in mice. Hum Mol Genet 2006 1.32
24 Genome-wide significance for a modifier of age at neurological onset in Huntington's disease at 6q23-24: the HD MAPS study. BMC Med Genet 2006 1.30
25 Considerations for genomewide association studies in Parkinson disease. Am J Hum Genet 2006 1.26
26 The relationship between CAG repeat length and age of onset differs for Huntington's disease patients with juvenile onset or adult onset. Ann Hum Genet 2006 1.26
27 Linkage analysis of a composite factor for the multiple metabolic syndrome: the National Heart, Lung, and Blood Institute Family Heart Study. Diabetes 2003 1.24
28 Genomewide association study for onset age in Parkinson disease. BMC Med Genet 2009 1.24
29 The etiopathogenesis of Parkinson disease and suggestions for future research. Part I. J Neuropathol Exp Neurol 2007 1.21
30 Evidence for a modifier of onset age in Huntington disease linked to the HD gene in 4p16. Neurogenetics 2004 1.19
31 A genome-wide scan of pulmonary function measures in the National Heart, Lung, and Blood Institute Family Heart Study. Am J Respir Crit Care Med 2003 1.19
32 PARK3 influences age at onset in Parkinson disease: a genome scan in the GenePD study. Am J Hum Genet 2002 1.19
33 Serum iron levels and the risk of Parkinson disease: a Mendelian randomization study. PLoS Med 2013 1.18
34 Linkage and association with pulmonary function measures on chromosome 6q27 in the Framingham Heart Study. Hum Mol Genet 2003 1.14
35 Genetic effect on blood pressure is modulated by age: the Hypertension Genetic Epidemiology Network Study. Hypertension 2008 1.10
36 LRRK2 is not a significant cause of Parkinson's disease in French-Canadians. Can J Neurol Sci 2007 1.09
37 Longitudinal and age trends of metabolic syndrome and its risk factors: the Family Heart Study. Nutr Metab (Lond) 2006 1.08
38 Human-specific histone methylation signatures at transcription start sites in prefrontal neurons. PLoS Biol 2012 1.08
39 Common SNP-based haplotype analysis of the 4p16.3 Huntington disease gene region. Am J Hum Genet 2012 1.05
40 A genome-wide scan for loci affecting normal adult height in the Framingham Heart Study. Hum Hered 2003 1.04
41 Estimating the probability of de novo HD cases from transmissions of expanded penetrant CAG alleles in the Huntington disease gene from male carriers of high normal alleles (27-35 CAG). Am J Med Genet A 2009 1.03
42 Copy number variation in familial Parkinson disease. PLoS One 2011 1.02
43 Assessment of cortical and striatal involvement in 523 Huntington disease brains. Neurology 2012 1.00
44 HaploBuild: an algorithm to construct non-contiguous associated haplotypes in family based genetic studies. Bioinformatics 2007 0.98
45 An evaluation of the metabolic syndrome in the HyperGEN study. Nutr Metab (Lond) 2005 0.97
46 Circulating soluble ICAM-1 levels shows linkage to ICAM gene cluster region on chromosome 19: the NHLBI Family Heart Study follow-up examination. Atherosclerosis 2007 0.97
47 State of the art review: molecular diagnosis of inherited movement disorders. Movement Disorders Society task force on molecular diagnosis. Mov Disord 2003 0.96
48 Influence of apolipoprotein E, smoking, and alcohol intake on carotid atherosclerosis: National Heart, Lung, and Blood Institute Family Heart Study. Stroke 2002 0.96
49 Brain-derived neurotrophic factor does not influence age at neurologic onset of Huntington's disease. Neurobiol Dis 2006 0.95
50 Leptin is associated with blood pressure and hypertension in women from the National Heart, Lung, and Blood Institute Family Heart Study. Hypertension 2009 0.94
51 Gene expression profiles in Parkinson disease prefrontal cortex implicate FOXO1 and genes under its transcriptional regulation. PLoS Genet 2012 0.94
52 Decreased glutamic acid decarboxylase mRNA expression in prefrontal cortex in Parkinson's disease. Exp Neurol 2010 0.92
53 Replication of association between ELAVL4 and Parkinson disease: the GenePD study. Hum Genet 2008 0.91
54 A genome-wide screen reveals evidence for a locus on chromosome 11 influencing variation in LDL cholesterol in the NHLBI Family Heart Study. Hum Genet 2002 0.91
55 Cyclin-G-associated kinase modifies α-synuclein expression levels and toxicity in Parkinson's disease: results from the GenePD Study. Hum Mol Genet 2011 0.91
56 Quantitative trait loci for metabolic syndrome in the Hypertension Genetic Epidemiology Network study. Obes Res 2005 0.89
57 Evaluation of Parkinson disease risk variants as expression-QTLs. PLoS One 2012 0.88
58 Is DFNA5 a susceptibility gene for age-related hearing impairment? Eur J Hum Genet 2002 0.86
59 Sepiapterin reductase expression is increased in Parkinson's disease brain tissue. Brain Res 2007 0.86
60 The etiopathogenesis of Parkinson disease and suggestions for future research. Part II. J Neuropathol Exp Neurol 2007 0.86
61 Genome-wide admixture mapping for coronary artery calcification in African Americans: the NHLBI Family Heart Study. Genet Epidemiol 2008 0.85
62 Evidence for a gene influencing heart rate on chromosome 5p13-14 in a meta-analysis of genome-wide scans from the NHLBI Family Blood Pressure Program. BMC Med Genet 2006 0.85
63 Polymorphisms near EXOC4 and LRGUK on chromosome 7q32 are associated with Type 2 Diabetes and fasting glucose; the NHLBI Family Heart Study. BMC Med Genet 2008 0.85
64 Quantitative trait loci on chromosome 8q24 for pancreatic beta-cell function and 7q11 for insulin sensitivity in obese nondiabetic white and black families: evidence from genome-wide linkage scans in the NHLBI Hypertension Genetic Epidemiology Network (HyperGEN) study. Diabetes 2006 0.84
65 Multiple genes influence BMI on chromosome 7q31-34: the NHLBI Family Heart Study. Obesity (Silver Spring) 2009 0.84
66 LIPC variants in the promoter and intron 1 modify HDL-C levels in a sex-specific fashion. Atherosclerosis 2008 0.84
67 Evidence for a gene influencing heart rate on chromosome 4 among hypertensives. Hum Genet 2002 0.84
68 Genetic analysis of the GRIK2 modifier effect in Huntington's disease. BMC Neurosci 2006 0.84
69 Postmortem Interval Influences α-Synuclein Expression in Parkinson Disease Brain. Parkinsons Dis 2012 0.83
70 Population stratification may bias analysis of PGC-1α as a modifier of age at Huntington disease motor onset. Hum Genet 2012 0.83
71 Genotype-by-sex interaction on fasting insulin concentration: the HyperGEN study. Diabetes 2007 0.83
72 Linkage analysis of diabetes status among hypertensive families: the Hypertension Genetic Epidemiology Network study. Diabetes 2004 0.82
73 Genomewide linkage study of modifiers of LRRK2-related Parkinson's disease. Mov Disord 2011 0.82
74 Estrogen-related and other disease diagnoses preceding Parkinson's disease. Clin Epidemiol 2010 0.81
75 Evidence of QTL on 15q21 for high-density lipoprotein cholesterol: the National Heart, Lung, and Blood Institute Family Heart Study (NHLBI FHS). Atherosclerosis 2006 0.81
76 Genome-wide linkage analyses for age at diagnosis of hypertension and early-onset hypertension in the HyperGEN study. Am J Hypertens 2004 0.81
77 TAA repeat variation in the GRIK2 gene does not influence age at onset in Huntington's disease. Biochem Biophys Res Commun 2012 0.81
78 A QTL on 12q influencing an inflammation marker and obesity in white women: the NHLBI Family Heart Study. Obesity (Silver Spring) 2008 0.79
79 Risk of Parkinson's disease after tamoxifen treatment. BMC Neurol 2010 0.79
80 Monozygotic twins discordant for Huntington disease after 7 years. Arch Neurol 2005 0.78
81 The analysis of survival data with a non-susceptible fraction and dual censoring mechanisms. Stat Med 2003 0.78
82 Apolipoprotein E polymorphism modifies the alcohol-HDL association observed in the National Heart, Lung, and Blood Institute Family Heart Study. Am J Clin Nutr 2004 0.78
83 Evidence for three novel QTLs for adiposity on chromosome 2 with epistatic interactions: the NHLBI Family Heart Study. Obesity (Silver Spring) 2009 0.77
84 Genome-wide scan identifies novel QTLs for cholesterol and LDL levels in F2[Dahl RxS]-intercross rats. Circ Res 2004 0.77
85 Candidate glutamatergic and dopaminergic pathway gene variants do not influence Huntington's disease motor onset. Neurogenetics 2013 0.77
86 Feasibility of Huntington disease trials in the disease prodrome. Neurology 2014 0.76
87 Absence of linkage or association for osteoarthritis with the vitamin D receptor/type II collagen locus: the Framingham Osteoarthritis Study. J Rheumatol 2002 0.76
88 Correction: RNA Sequence Analysis of Human Huntington Disease Brain Reveals an Extensive Increase in Inflammatory and Developmental Gene Expression. PLoS One 2016 0.75
89 The association of cell cycle checkpoint 2 variants and kidney function: findings of the Family Blood Pressure Program and the Atherosclerosis Risk In Communities study. Am J Hypertens 2009 0.75
90 Comprehensive linkage and linkage heterogeneity analysis of 4344 sibling pairs affected with hypertension from the Family Blood Pressure Program. Genet Epidemiol 2007 0.75