Mathieu Lesort

Author PubWeight™ 16.48‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Mutant huntingtin directly increases susceptibility of mitochondria to the calcium-induced permeability transition and cytochrome c release. Hum Mol Genet 2004 2.31
2 HD CAG repeat implicates a dominant property of huntingtin in mitochondrial energy metabolism. Hum Mol Genet 2005 1.96
3 Striatal cells from mutant huntingtin knock-in mice are selectively vulnerable to mitochondrial complex II inhibitor-induced cell death through a non-apoptotic pathway. Hum Mol Genet 2004 1.19
4 Immunophilin deficiency augments Ca2+-dependent glutamate release from mouse cortical astrocytes. Cell Calcium 2010 0.94
5 Cystamine and cysteamine prevent 3-NP-induced mitochondrial depolarization of Huntington's disease knock-in striatal cells. Eur J Neurosci 2006 0.93
6 Involvement of the mitochondrial permeability transition pore in chronic ethanol-mediated liver injury in mice. Am J Physiol Gastrointest Liver Physiol 2013 0.92
7 Mitochondrial calcium uptake capacity as a therapeutic target in the R6/2 mouse model of Huntington's disease. Hum Mol Genet 2010 0.92
8 14-3-3theta protects against neurotoxicity in a cellular Parkinson's disease model through inhibition of the apoptotic factor Bax. PLoS One 2011 0.89
9 Ubiquitin-proteasome system alterations in a striatal cell model of Huntington's disease. J Neurosci Res 2007 0.87
10 Increased glutathione levels in cortical and striatal mitochondria of the R6/2 Huntington's disease mouse model. Neurosci Lett 2005 0.86
11 Enhanced Ca(2+)-dependent glutamate release from astrocytes of the BACHD Huntington's disease mouse model. Neurobiol Dis 2013 0.86
12 Tissue transglutaminase overexpression does not modify the disease phenotype of the R6/2 mouse model of Huntington's disease. Exp Neurol 2012 0.83
13 Human cytomegalovirus UL97 kinase prevents the deposition of mutant protein aggregates in cellular models of Huntington's disease and ataxia. Neurobiol Dis 2010 0.79
14 Transient osmotic stress facilitates mutant huntingtin aggregation. Neuroreport 2002 0.78
15 Mutant huntingtin aggregates do not sensitize cells to apoptotic stressors. FEBS Lett 2002 0.77
16 Verification of somatic CAG repeat expansion by pre-PCR fractionation. J Neurosci Methods 2004 0.76