Published in Clin Cancer Res on August 15, 2005
Stem cell factor SALL4 represses the transcriptions of PTEN and SALL1 through an epigenetic repressor complex. PLoS One (2009) 1.77
Cancer stem cells as mediators of treatment resistance in brain tumors: status and controversies. Neoplasia (2007) 1.62
Development of a tumor-selective approach to treat metastatic cancer. PLoS One (2006) 1.46
Neural stem cell-mediated enzyme/prodrug therapy for glioma: preclinical studies. Sci Transl Med (2013) 1.42
Metzincin proteases and their inhibitors: foes or friends in nervous system physiology? J Neurosci (2010) 1.41
Mesenchymal stem cells engineered for cancer therapy. Adv Drug Deliv Rev (2011) 1.26
Therapeutic efficacy and safety of TRAIL-producing human adipose tissue-derived mesenchymal stem cells against experimental brainstem glioma. Neuro Oncol (2010) 1.04
Achieving stable human stem cell engraftment and survival in the CNS: is the future of regenerative medicine immunodeficient? Regen Med (2011) 1.03
Applications of neural and mesenchymal stem cells in the treatment of gliomas. Expert Rev Anticancer Ther (2009) 0.97
Stem cell-based therapies for cancer treatment: separating hope from hype. Nat Rev Cancer (2014) 0.96
Stem cells as therapeutic vehicles for the treatment of high-grade gliomas. Neuro Oncol (2011) 0.96
Human neural stem cells can target and deliver therapeutic genes to breast cancer brain metastases. Mol Ther (2009) 0.92
Migration of human neural stem cells toward an intracranial glioma. Exp Mol Med (2008) 0.92
Strategies in gene therapy for glioblastoma. Cancers (Basel) (2013) 0.87
Gliomagenesis and the use of neural stem cells in brain tumor treatment. Anticancer Agents Med Chem (2010) 0.86
Proteolytically Derived Endogenous Angioinhibitors Originating from the Extracellular Matrix. Pharmaceuticals (Basel) (2011) 0.84
Neural Stem Cells Secreting Anti-HER2 Antibody Improve Survival in a Preclinical Model of HER2 Overexpressing Breast Cancer Brain Metastases. Stem Cells (2015) 0.81
Human nerual stem cells for brain repair. Int J Stem Cells (2008) 0.80
Migration of mouse-induced pluripotent stem cells to glioma-conditioned medium is mediated by tumor-associated specific growth factors. Oncol Lett (2011) 0.80
Novel treatment strategies for malignant gliomas using neural stem cells. Neurotherapeutics (2009) 0.77
Encapsulated stem cells for cancer therapy. Biomatter (2013) 0.77
Stem cell-based therapies for tumors in the brain: are we there yet? Neuro Oncol (2016) 0.77
Use of genetically engineered stem cells for glioma therapy. Oncol Lett (2015) 0.75
Neurotransplantation: lux et veritas, fiction or reality? J Neurosurg Sci (2011) 0.75
Ultrasound-Mediated Mesenchymal Stem Cells Transfection as a Targeted Cancer Therapy Platform. Sci Rep (2017) 0.75
Tumor-specific gene therapy for pancreatic cancer using human neural stem cells encoding carboxylesterase. Oncotarget (2016) 0.75
Prediction of central nervous system embryonal tumour outcome based on gene expression. Nature (2002) 15.36
Gene expression-based classification of malignant gliomas correlates better with survival than histological classification. Cancer Res (2003) 8.06
The impact of human EGFR kinase domain mutations on lung tumorigenesis and in vivo sensitivity to EGFR-targeted therapies. Cancer Cell (2006) 5.34
Bronchial and peripheral murine lung carcinomas induced by T790M-L858R mutant EGFR respond to HKI-272 and rapamycin combination therapy. Cancer Cell (2007) 4.85
Anti-inflammatory mechanism of intravascular neural stem cell transplantation in haemorrhagic stroke. Brain (2007) 3.68
A murine lung cancer co-clinical trial identifies genetic modifiers of therapeutic response. Nature (2012) 3.24
Central precocious puberty caused by mutations in the imprinted gene MKRN3. N Engl J Med (2013) 3.04
Somatic activation of AKT3 causes hemispheric developmental brain malformations. Neuron (2012) 2.84
Epidemiology of intracranial meningioma. Neurosurgery (2005) 2.60
A 24-year-old woman with intractable seizures: review of surgery for epilepsy. JAMA (2008) 2.55
Mutations in BRAF and KRAS converge on activation of the mitogen-activated protein kinase pathway in lung cancer mouse models. Cancer Res (2007) 2.45
Efficacy of a rapamycin analog (CCI-779) and IFN-gamma in tuberous sclerosis mouse models. Genes Chromosomes Cancer (2005) 2.42
The prognostic significance of phosphatidylinositol 3-kinase pathway activation in human gliomas. J Clin Oncol (2004) 2.24
Behavioral improvement in a primate Parkinson's model is associated with multiple homeostatic effects of human neural stem cells. Proc Natl Acad Sci U S A (2007) 2.19
Epidermal growth factor receptor variant III mutations in lung tumorigenesis and sensitivity to tyrosine kinase inhibitors. Proc Natl Acad Sci U S A (2006) 2.17
Human neural stem cell transplantation promotes functional recovery in rats with experimental intracerebral hemorrhage. Stroke (2003) 1.97
Survival rates in patients with low-grade glioma after intraoperative magnetic resonance image guidance. Cancer (2005) 1.97
Renal injury is a third hit promoting rapid development of adult polycystic kidney disease. Hum Mol Genet (2009) 1.94
Neurosurgery certification in member societies of the WFNS: global overview. World Neurosurg (2011) 1.87
Semaphorin-3F is an inhibitor of tumor angiogenesis. Cancer Res (2004) 1.70
Neural stem cell tropism to glioma: critical role of tumor hypoxia. Mol Cancer Res (2008) 1.67
Intravascular delivery of neural stem cell lines to target intracranial and extracranial tumors of neural and non-neural origin. Hum Gene Ther (2003) 1.65
History of allergies and autoimmune diseases and risk of brain tumors in adults. Int J Cancer (2002) 1.62
Transplantation of human neural stem cells exerts neuroprotection in a rat model of Parkinson's disease. J Neurosci (2006) 1.59
Delivery of AAV-IGF-1 to the CNS extends survival in ALS mice through modification of aberrant glial cell activity. Mol Ther (2008) 1.57
Targeting of melanoma brain metastases using engineered neural stem/progenitor cells. Neuro Oncol (2006) 1.57
Brain transplantation of immortalized human neural stem cells promotes functional recovery in mouse intracerebral hemorrhage stroke model. Stem Cells (2007) 1.57
Human neural stem cells improve sensorimotor deficits in the adult rat brain with experimental focal ischemia. Brain Res (2004) 1.55
A genome-wide screen reveals functional gene clusters in the cancer genome and identifies EphA2 as a mitogen in glioblastoma. Cancer Res (2006) 1.54
Phase II study of protracted daily temozolomide for low-grade gliomas in adults. Clin Cancer Res (2009) 1.52
DNA repair gene polymorphisms and risk of adult meningioma, glioma, and acoustic neuroma. Neuro Oncol (2009) 1.51
Reproductive and hormonal factors and risk of brain tumors in adult females. Int J Cancer (2005) 1.50
Survival rates and patterns of care for patients diagnosed with supratentorial low-grade gliomas: data from the SEER program, 1973-2001. Cancer (2006) 1.49
Development of a tumor-selective approach to treat metastatic cancer. PLoS One (2006) 1.46
Diffusion imaging of brain tumors. NMR Biomed (2010) 1.45
Sodium selenite induces superoxide-mediated mitochondrial damage and subsequent autophagic cell death in malignant glioma cells. Cancer Res (2007) 1.45
Human neural stem cells target experimental intracranial medulloblastoma and deliver a therapeutic gene leading to tumor regression. Clin Cancer Res (2006) 1.44
Cyclooxygenase-2 inhibitor, celecoxib, inhibits the altered hippocampal neurogenesis with attenuation of spontaneous recurrent seizures following pilocarpine-induced status epilepticus. Neurobiol Dis (2006) 1.43
Neural stem cell-mediated enzyme/prodrug therapy for glioma: preclinical studies. Sci Transl Med (2013) 1.42
Supratentorial low-grade glioma resectability: statistical predictive analysis based on anatomic MR features and tumor characteristics. Radiology (2006) 1.42
Human neural stem cells over-expressing VEGF provide neuroprotection, angiogenesis and functional recovery in mouse stroke model. PLoS One (2007) 1.41
Brain tumor tropism of transplanted human neural stem cells is induced by vascular endothelial growth factor. Neoplasia (2005) 1.41
Non-rigid alignment of pre-operative MRI, fMRI, and DT-MRI with intra-operative MRI for enhanced visualization and navigation in image-guided neurosurgery. Neuroimage (2006) 1.41
In vitro and in vivo activity of the nuclear factor-kappaB inhibitor sulfasalazine in human glioblastomas. Clin Cancer Res (2004) 1.40
Human bone marrow-derived mesenchymal stromal cells expressing S-TRAIL as a cellular delivery vehicle for human glioma therapy. Stem Cells (2009) 1.40
Immediate titanium mesh cranioplasty for treatment of postcraniotomy infections. World Neurosurg (2011) 1.39
Neurosurgery certification in member societies of the WFNS: Europe. World Neurosurg (2011) 1.39
Cytokines, chemokines, and cytokine receptors in human microglia. J Neurosci Res (2002) 1.39
Human neural stem cells can migrate, differentiate, and integrate after intravenous transplantation in adult rats with transient forebrain ischemia. Neurosci Lett (2003) 1.39
Tumor-targeted enzyme/prodrug therapy mediates long-term disease-free survival of mice bearing disseminated neuroblastoma. Cancer Res (2007) 1.38
Targeting rat brainstem glioma using human neural stem cells and human mesenchymal stem cells. Clin Cancer Res (2009) 1.38
Iron labeling and pre-clinical MRI visualization of therapeutic human neural stem cells in a murine glioma model. PLoS One (2009) 1.36
Capturing intraoperative deformations: research experience at Brigham and Women's Hospital. Med Image Anal (2004) 1.35
Intracranial delivery of CLN2 reduces brain pathology in a mouse model of classical late infantile neuronal ceroid lipofuscinosis. J Neurosci (2006) 1.33
Fractalkine and fractalkine receptors in human neurons and glial cells. J Neurosci Res (2002) 1.32
Urokinase plasminogen activator and urokinase plasminogen activator receptor mediate human stem cell tropism to malignant solid tumors. Stem Cells (2008) 1.30
Transplantation of human mesenchymal stem cells promotes functional improvement and increased expression of neurotrophic factors in a rat focal cerebral ischemia model. J Neurosci Res (2010) 1.30
Increased lysis of stem cells but not their differentiated cells by natural killer cells; de-differentiation or reprogramming activates NK cells. PLoS One (2010) 1.28
Genetic polymorphisms in GSTM1, -P1, -T1, and CYP2E1 and the risk of adult brain tumors. Cancer Epidemiol Biomarkers Prev (2003) 1.28
Volume reconstruction techniques improve the correlation between histological and in vivo tumor volume measurements in mouse models of human gliomas. J Neurooncol (2004) 1.27
Indole-3-carbinol (I3C) exhibits inhibitory and preventive effects on prostate tumors in mice. Food Chem Toxicol (2007) 1.26
SNAI2/Slug promotes growth and invasion in human gliomas. BMC Cancer (2010) 1.26
Cell-specific alterations of glutamate receptor expression in tuberous sclerosis complex cortical tubers. Ann Neurol (2008) 1.26
Lead, genetic susceptibility, and risk of adult brain tumors. Cancer Epidemiol Biomarkers Prev (2006) 1.23
Minocycline inhibits neuronal death and glial activation induced by beta-amyloid peptide in rat hippocampus. Glia (2004) 1.21
Modulation of the purinergic P2X7 receptor attenuates lipopolysaccharide-mediated microglial activation and neuronal damage in inflamed brain. J Neurosci (2007) 1.21
Acellular cardiac extracellular matrix as a scaffold for tissue engineering: in vitro cell support, remodeling, and biocompatibility. Tissue Eng Part C Methods (2010) 1.20
Exogenous hormone use and meningioma risk: what do we tell our patients? Cancer (2007) 1.20
Coordinate activation of Shh and PI3K signaling in PTEN-deficient glioblastoma: new therapeutic opportunities. Nat Med (2013) 1.19
Intravenously transplanted human neural stem cells migrate to the injured spinal cord in adult mice in an SDF-1- and HGF-dependent manner. Neurosci Lett (2007) 1.18
Roscovitine sensitizes glioma cells to TRAIL-mediated apoptosis by downregulation of survivin and XIAP. Oncogene (2004) 1.18
Aberrant splicing of cyclin-dependent kinase-associated protein phosphatase KAP increases proliferation and migration in glioblastoma. Cancer Res (2007) 1.17
Naturally derived anti-inflammatory compounds from Chinese medicinal plants. J Ethnopharmacol (2012) 1.17
Reproductive hormone-dependent and -independent contributions to developmental changes in kisspeptin in GnRH-deficient hypogonadal mice. PLoS One (2010) 1.17
Polymorphisms in apoptosis and cell cycle control genes and risk of brain tumors in adults. Cancer Epidemiol Biomarkers Prev (2007) 1.17
IL-8 enhancement of amyloid-beta (Abeta 1-42)-induced expression and production of pro-inflammatory cytokines and COX-2 in cultured human microglia. J Neuroimmunol (2004) 1.17
Stem cell-based cell therapy for spinal cord injury. Cell Transplant (2007) 1.15
Continuous intracranial administration of suberoylanilide hydroxamic acid (SAHA) inhibits tumor growth in an orthotopic glioma model. J Neurooncol (2007) 1.15
Proactive transplantation of human neural stem cells prevents degeneration of striatal neurons in a rat model of Huntington disease. Neurobiol Dis (2004) 1.15
Ex vivo VEGF delivery by neural stem cells enhances proliferation of glial progenitors, angiogenesis, and tissue sparing after spinal cord injury. PLoS One (2009) 1.15
Neural progenitor NT2N cell lines from teratocarcinoma for transplantation therapy in stroke. Prog Neurobiol (2008) 1.15
Image-guided neurosurgery at Brigham and Women's Hospital. IEEE Eng Med Biol Mag (2006) 1.14
Gene transfer of human acid sphingomyelinase corrects neuropathology and motor deficits in a mouse model of Niemann-Pick type A disease. Proc Natl Acad Sci U S A (2005) 1.14