Published in J Neurosci on August 24, 2005
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APOE4 allele disrupts resting state fMRI connectivity in the absence of amyloid plaques or decreased CSF Aβ42. J Neurosci (2010) 2.99
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The cortical signature of prodromal AD: regional thinning predicts mild AD dementia. Neurology (2008) 2.91
Spatial correlation between brain aerobic glycolysis and amyloid-β (Aβ ) deposition. Proc Natl Acad Sci U S A (2010) 2.80
Functional alterations in memory networks in early Alzheimer's disease. Neuromolecular Med (2010) 2.77
Age-related memory impairment associated with loss of parietal deactivation but preserved hippocampal activation. Proc Natl Acad Sci U S A (2008) 2.65
Revealing modular architecture of human brain structural networks by using cortical thickness from MRI. Cereb Cortex (2008) 2.62
Automated MRI measures identify individuals with mild cognitive impairment and Alzheimer's disease. Brain (2009) 2.61
One-year brain atrophy evident in healthy aging. J Neurosci (2009) 2.61
Alzheimer's disease is associated with reduced expression of energy metabolism genes in posterior cingulate neurons. Proc Natl Acad Sci U S A (2008) 2.59
Amyloid-β associated cortical thinning in clinically normal elderly. Ann Neurol (2011) 2.57
Trafficking and proteolytic processing of APP. Cold Spring Harb Perspect Med (2012) 2.56
Amyloid-beta dynamics correlate with neurological status in the injured human brain. Science (2008) 2.53
Resting state functional connectivity of the striatum in Parkinson's disease. Brain (2012) 2.53
The brain's default network and its adaptive role in internal mentation. Neuroscientist (2011) 2.48
Default mode network connectivity in stable vs progressive mild cognitive impairment. Neurology (2011) 2.44
The restless brain. Brain Connect (2011) 2.44
Mechanism of Ca2+ disruption in Alzheimer's disease by presenilin regulation of InsP3 receptor channel gating. Neuron (2008) 2.40
Effect of APOE ε4 status on intrinsic network connectivity in cognitively normal elderly subjects. Arch Neurol (2011) 2.40
The influence of Alzheimer disease family history and apolipoprotein E epsilon4 on mesial temporal lobe activation. J Neurosci (2006) 2.34
Amyloid-beta as a positive endogenous regulator of release probability at hippocampal synapses. Nat Neurosci (2009) 2.31
Functional connectivity in autosomal dominant and late-onset Alzheimer disease. JAMA Neurol (2014) 2.28
Loss of intranetwork and internetwork resting state functional connections with Alzheimer's disease progression. J Neurosci (2012) 2.26
Regional white matter volume differences in nondemented aging and Alzheimer's disease. Neuroimage (2008) 2.23
Amyloid imaging and CSF biomarkers in predicting cognitive impairment up to 7.5 years later. Neurology (2013) 2.19
Amyloid beta from axons and dendrites reduces local spine number and plasticity. Nat Neurosci (2009) 2.18
Loss of 'small-world' networks in Alzheimer's disease: graph analysis of FMRI resting-state functional connectivity. PLoS One (2010) 2.12
Transsynaptic progression of amyloid-β-induced neuronal dysfunction within the entorhinal-hippocampal network. Neuron (2010) 2.10
Differential effects of aging and Alzheimer's disease on medial temporal lobe cortical thickness and surface area. Neurobiol Aging (2007) 2.09
Age, Alzheimer's disease and dementia in the Baltimore Longitudinal Study of Ageing. Brain (2010) 2.04
The default network and self-generated thought: component processes, dynamic control, and clinical relevance. Ann N Y Acad Sci (2014) 2.02
Distinct MRI atrophy patterns in autopsy-proven Alzheimer's disease and frontotemporal lobar degeneration. Am J Alzheimers Dis Other Demen (2008) 2.00
Aging and functional brain networks. Mol Psychiatry (2011) 1.99
Functional network disruption in the degenerative dementias. Lancet Neurol (2011) 1.98
Noninvasive quantification of whole-brain cerebral metabolic rate of oxygen (CMRO2) by MRI. Magn Reson Med (2009) 1.97
The neuropsychological profile of Alzheimer disease. Cold Spring Harb Perspect Med (2012) 1.93
The episodic memory system: neurocircuitry and disorders. Neuropsychopharmacology (2010) 1.91
Neuronal dysfunction and disconnection of cortical hubs in non-demented subjects with elevated amyloid burden. Brain (2011) 1.89
Acute stress increases interstitial fluid amyloid-beta via corticotropin-releasing factor and neuronal activity. Proc Natl Acad Sci U S A (2007) 1.89
Basal cerebral metabolism may modulate the cognitive effects of Abeta in mild cognitive impairment: an example of brain reserve. J Neurosci (2009) 1.89
Resting-state BOLD networks versus task-associated functional MRI for distinguishing Alzheimer's disease risk groups. Neuroimage (2009) 1.89
Relationships between β-amyloid and functional connectivity in different components of the default mode network in aging. Cereb Cortex (2011) 1.87
Overlapping and non-overlapping brain regions for theory of mind and self reflection in individual subjects. Soc Cogn Affect Neurosci (2006) 1.87
Resting state functional connectivity in preclinical Alzheimer's disease. Biol Psychiatry (2013) 1.86
Increased metabolic vulnerability in early-onset Alzheimer's disease is not related to amyloid burden. Brain (2010) 1.86
Neural correlates of Alzheimer's disease and mild cognitive impairment: a systematic and quantitative meta-analysis involving 1351 patients. Neuroimage (2009) 1.85
Regionally selective atrophy after traumatic axonal injury. Arch Neurol (2010) 1.83
When less is more: TPJ and default network deactivation during encoding predicts working memory performance. Neuroimage (2009) 1.83
Functional abnormalities of the medial temporal lobe memory system in mild cognitive impairment and Alzheimer's disease: insights from functional MRI studies. Neuropsychologia (2007) 1.81
Intraneuronal beta-amyloid accumulation and synapse pathology in Alzheimer's disease. Acta Neuropathol (2010) 1.80
β-amyloid disrupts human NREM slow waves and related hippocampus-dependent memory consolidation. Nat Neurosci (2015) 1.79
Hippocampal and ventral medial prefrontal activation during retrieval-mediated learning supports novel inference. Neuron (2012) 1.77
Age, Alzheimer disease, and brain structure. Neurology (2009) 1.75
Predicting cognitive decline in subjects at risk for Alzheimer disease by using combined cerebrospinal fluid, MR imaging, and PET biomarkers. Radiology (2012) 1.74
Disrupted energy metabolism and neuronal circuit dysfunction in cognitive impairment and Alzheimer's disease. Lancet Neurol (2010) 1.71
3D PIB and CSF biomarker associations with hippocampal atrophy in ADNI subjects. Neurobiol Aging (2010) 1.70
β-Amyloid affects frontal and posterior brain networks in normal aging. Neuroimage (2010) 1.68
The human brain is intrinsically organized into dynamic, anticorrelated functional networks. Proc Natl Acad Sci U S A (2005) 37.57
The diagnosis of dementia due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement (2011) 24.26
Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-B. Ann Neurol (2004) 21.56
Spurious but systematic correlations in functional connectivity MRI networks arise from subject motion. Neuroimage (2011) 19.70
Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease. Nat Genet (2009) 15.15
Clinical and biomarker changes in dominantly inherited Alzheimer's disease. N Engl J Med (2012) 14.14
Consensus nomenclature for in vivo imaging of reversibly binding radioligands. J Cereb Blood Flow Metab (2007) 11.79
Inverse relation between in vivo amyloid imaging load and cerebrospinal fluid Abeta42 in humans. Ann Neurol (2006) 11.23
Distinct brain networks for adaptive and stable task control in humans. Proc Natl Acad Sci U S A (2007) 11.19
Cerebrospinal fluid tau/beta-amyloid(42) ratio as a prediction of cognitive decline in nondemented older adults. Arch Neurol (2007) 10.75
Spontaneous neuronal activity distinguishes human dorsal and ventral attention systems. Proc Natl Acad Sci U S A (2006) 10.09
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. Nat Genet (2011) 10.07
Coherent spontaneous activity identifies a hippocampal-parietal memory network. J Neurophysiol (2006) 9.65
The global signal and observed anticorrelated resting state brain networks. J Neurophysiol (2009) 9.64
11C PiB and structural MRI provide complementary information in imaging of Alzheimer's disease and amnestic mild cognitive impairment. Brain (2008) 9.64
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease. Nat Genet (2011) 9.23
A default mode of brain function: a brief history of an evolving idea. Neuroimage (2007) 8.85
Thinning of the cerebral cortex in aging. Cereb Cortex (2004) 8.31
Disruption of large-scale brain systems in advanced aging. Neuron (2007) 8.12
Decreased clearance of CNS beta-amyloid in Alzheimer's disease. Science (2010) 8.04
Frequent amyloid deposition without significant cognitive impairment among the elderly. Arch Neurol (2008) 7.95
Open Access Series of Imaging Studies (OASIS): cross-sectional MRI data in young, middle aged, nondemented, and demented older adults. J Cogn Neurosci (2007) 7.31
Evidence for a frontoparietal control system revealed by intrinsic functional connectivity. J Neurophysiol (2008) 7.12
Parietal lobe contributions to episodic memory retrieval. Trends Cogn Sci (2005) 7.04
Brain work and brain imaging. Annu Rev Neurosci (2006) 6.99
Use of florbetapir-PET for imaging beta-amyloid pathology. JAMA (2011) 6.92
Beta-amyloid imaging and memory in non-demented individuals: evidence for preclinical Alzheimer's disease. Brain (2007) 6.39
Kinetic modeling of amyloid binding in humans using PET imaging and Pittsburgh Compound-B. J Cereb Blood Flow Metab (2005) 6.25
Intrinsic fluctuations within cortical systems account for intertrial variability in human behavior. Neuron (2007) 6.23
APOE predicts amyloid-beta but not tau Alzheimer pathology in cognitively normal aging. Ann Neurol (2010) 6.17
Post-mortem correlates of in vivo PiB-PET amyloid imaging in a typical case of Alzheimer's disease. Brain (2008) 5.89
Coherent spontaneous activity accounts for trial-to-trial variability in human evoked brain responses. Nat Neurosci (2005) 5.83
Functional deactivations: change with age and dementia of the Alzheimer type. Proc Natl Acad Sci U S A (2003) 5.64
TDP-43 A315T mutation in familial motor neuron disease. Ann Neurol (2008) 5.58
Fibrillar amyloid-beta burden in cognitively normal people at 3 levels of genetic risk for Alzheimer's disease. Proc Natl Acad Sci U S A (2009) 5.55
Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions. Nat Genet (2010) 5.52
The Alzheimer's Disease Centers' Uniform Data Set (UDS): the neuropsychologic test battery. Alzheimer Dis Assoc Disord (2009) 5.50
Breakdown of functional connectivity in frontoparietal networks underlies behavioral deficits in spatial neglect. Neuron (2007) 5.40
The cortical signature of Alzheimer's disease: regionally specific cortical thinning relates to symptom severity in very mild to mild AD dementia and is detectable in asymptomatic amyloid-positive individuals. Cereb Cortex (2008) 5.36
Detection of blast-related traumatic brain injury in U.S. military personnel. N Engl J Med (2011) 5.34
Synthesis and evaluation of 11C-labeled 6-substituted 2-arylbenzothiazoles as amyloid imaging agents. J Med Chem (2003) 5.34
Simplified quantification of Pittsburgh Compound B amyloid imaging PET studies: a comparative analysis. J Nucl Med (2005) 5.10
Human amyloid-beta synthesis and clearance rates as measured in cerebrospinal fluid in vivo. Nat Med (2006) 5.09
11C-PiB PET assessment of change in fibrillar amyloid-beta load in patients with Alzheimer's disease treated with bapineuzumab: a phase 2, double-blind, placebo-controlled, ascending-dose study. Lancet Neurol (2010) 5.03
TDP-43 in familial and sporadic frontotemporal lobar degeneration with ubiquitin inclusions. Am J Pathol (2007) 5.02
The National Alzheimer's Coordinating Center (NACC) database: the Uniform Data Set. Alzheimer Dis Assoc Disord (2007) 5.01
Alzheimer's disease: the challenge of the second century. Sci Transl Med (2011) 4.88
Decreased cerebrospinal fluid Abeta(42) correlates with brain atrophy in cognitively normal elderly. Ann Neurol (2009) 4.71
A method for using blocked and event-related fMRI data to study "resting state" functional connectivity. Neuroimage (2007) 4.60
Pittsburgh compound B imaging and prediction of progression from cognitive normality to symptomatic Alzheimer disease. Arch Neurol (2009) 4.55
Longitudinal assessment of Aβ and cognition in aging and Alzheimer disease. Ann Neurol (2011) 4.38
Neuropathology of nondemented aging: presumptive evidence for preclinical Alzheimer disease. Neurobiol Aging (2009) 4.36
Electrophysiological correlates of the brain's intrinsic large-scale functional architecture. Proc Natl Acad Sci U S A (2008) 4.32
The Alzheimer's Disease Neuroimaging Initiative: a review of papers published since its inception. Alzheimers Dement (2011) 4.25
Imaging of amyloid burden and distribution in cerebral amyloid angiopathy. Ann Neurol (2007) 4.11
Human apoE isoforms differentially regulate brain amyloid-β peptide clearance. Sci Transl Med (2011) 4.07
The default mode network and self-referential processes in depression. Proc Natl Acad Sci U S A (2009) 4.05
Amyloid deposition begins in the striatum of presenilin-1 mutation carriers from two unrelated pedigrees. J Neurosci (2007) 3.91
Differential vulnerability of anterior white matter in nondemented aging with minimal acceleration in dementia of the Alzheimer type: evidence from diffusion tensor imaging. Cereb Cortex (2004) 3.87
Methods to detect, characterize, and remove motion artifact in resting state fMRI. Neuroimage (2013) 3.86
The Alzheimer's disease neuroimaging initiative: progress report and future plans. Alzheimers Dement (2010) 3.85
Molecular imaging with Pittsburgh Compound B confirmed at autopsy: a case report. Arch Neurol (2007) 3.83
The temporal structures and functional significance of scale-free brain activity. Neuron (2010) 3.78
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Cerebrospinal fluid tau and beta-amyloid: how well do these biomarkers reflect autopsy-confirmed dementia diagnoses? Arch Neurol (2003) 3.75
Efficacy of pazopanib in progressive, radioiodine-refractory, metastatic differentiated thyroid cancers: results of a phase 2 consortium study. Lancet Oncol (2010) 3.75
Amyloid plaques disrupt resting state default mode network connectivity in cognitively normal elderly. Biol Psychiatry (2009) 3.72
Longitudinal course and neuropathologic outcomes in original vs revised MCI and in pre-MCI. Neurology (2006) 3.69
Mild cognitive impairment as a clinical entity and treatment target. Arch Neurol (2005) 3.69
Cerebral PET with florbetapir compared with neuropathology at autopsy for detection of neuritic amyloid-β plaques: a prospective cohort study. Lancet Neurol (2012) 3.66
Cognitive decline and brain volume loss as signatures of cerebral amyloid-beta peptide deposition identified with Pittsburgh compound B: cognitive decline associated with Abeta deposition. Arch Neurol (2009) 3.60
Plasma multianalyte profiling in mild cognitive impairment and Alzheimer disease. Neurology (2012) 3.58