Role of folate receptor genes in reproduction and related cancers.

PubWeight™: 1.02‹?› | Rank: Top 15%

🔗 View Article (PMID 16146749)

Published in Front Biosci on January 01, 2006

Authors

Hala Elnakat1, Manohar Ratnam

Author Affiliations

1: Department of Biochemistry and Cancer Biology, Medical College of Ohio, Toledo, OH 43614-5804, USA.

Articles citing this

Beyond chemotherapy: targeted therapies in ovarian cancer. Nat Rev Cancer (2009) 3.46

Folate receptor alpha as a tumor target in epithelial ovarian cancer. Gynecol Oncol (2008) 2.01

Folate receptor alpha expression in lung cancer: diagnostic and prognostic significance. Oncotarget (2012) 1.67

HFT-T, a targeting nanoparticle, enhances specific delivery of paclitaxel to folate receptor-positive tumors. ACS Nano (2009) 1.29

Immunity and immune suppression in human ovarian cancer. Immunotherapy (2011) 1.07

A current review of targeted therapeutics for ovarian cancer. J Oncol (2010) 1.02

Association between blocking folate receptor autoantibodies and subfertility. Fertil Steril (2008) 0.91

The reduced folate carrier (RFC) is cytotoxic to cells under conditions of severe folate deprivation. RFC as a double edged sword in folate homeostasis. J Biol Chem (2008) 0.88

Accelerated killing of cancer cells using a multifunctional single-walled carbon nanotube-based system for targeted drug delivery in combination with photothermal therapy. Int J Nanomedicine (2013) 0.88

Retracted Targeted immune therapy of ovarian cancer. Cancer Metastasis Rev (2015) 0.84

Clinical trials and future potential of targeted therapy for ovarian cancer. Int J Clin Oncol (2012) 0.83

Vintafolide: a novel targeted therapy for the treatment of folate receptor expressing tumors. Ther Adv Med Oncol (2015) 0.82

Folate receptor α expression and significance in endometrioid endometrium carcinoma and endometrial hyperplasia. Int J Clin Exp Pathol (2015) 0.77

Targeted therapies in epithelial ovarian cancer. Cancers (Basel) (2010) 0.77

Tumor Targeting and Pharmacokinetics of a Near-Infrared Fluorescent-Labeled δ-Opioid Receptor Antagonist Agent, Dmt-Tic-Cy5. Mol Pharm (2016) 0.75

Folic acid tagged nanoceria as a novel therapeutic agent in ovarian cancer. BMC Cancer (2016) 0.75

Articles by these authors

Distribution, functionality and gene regulation of folate receptor isoforms: implications in targeted therapy. Adv Drug Deliv Rev (2004) 2.56

The folate receptor: what does it promise in tissue-targeted therapeutics? Cancer Metastasis Rev (2007) 1.84

Folate receptor beta as a potential delivery route for novel folate antagonists to macrophages in the synovial tissue of rheumatoid arthritis patients. Arthritis Rheum (2009) 1.77

Folate receptor beta is expressed by tumor-associated macrophages and constitutes a marker for M2 anti-inflammatory/regulatory macrophages. Cancer Res (2009) 1.71

Structures of human folate receptors reveal biological trafficking states and diversity in folate and antifolate recognition. Proc Natl Acad Sci U S A (2013) 1.28

Strategy for the treatment of acute myelogenous leukemia based on folate receptor beta-targeted liposomal doxorubicin combined with receptor induction using all-trans retinoic acid. Blood (2002) 1.22

Modulation of the folate receptor alpha gene by the estrogen receptor: mechanism and implications in tumor targeting. Cancer Res (2003) 1.15

Synergistic induction of folate receptor beta by all-trans retinoic acid and histone deacetylase inhibitors in acute myelogenous leukemia cells: mechanism and utility in enhancing selective growth inhibition by antifolates. Cancer Res (2006) 1.01

The ETS domain transcription factor ELK1 directs a critical component of growth signaling by the androgen receptor in prostate cancer cells. J Biol Chem (2013) 0.95

Role of formulation composition in folate receptor-targeted liposomal doxorubicin delivery to acute myelogenous leukemia cells. Mol Pharm (2007) 0.95

Modulation of the folate receptor type beta gene by coordinate actions of retinoic acid receptors at activator Sp1/ets and repressor AP-1 sites. Blood (2003) 0.93

R5020 and RU486 act as progesterone receptor agonists to enhance Sp1/Sp4-dependent gene transcription by an indirect mechanism. Mol Endocrinol (2006) 0.92

During hormone depletion or tamoxifen treatment of breast cancer cells the estrogen receptor apoprotein supports cell cycling through the retinoic acid receptor α1 apoprotein. Breast Cancer Res (2011) 0.91

Hormone depletion-insensitivity of prostate cancer cells is supported by the AR without binding to classical response elements. Mol Endocrinol (2011) 0.86

Targeting human clonogenic acute myelogenous leukemia cells via folate conjugated liposomes combined with receptor modulation by all-trans retinoic acid. Int J Pharm (2010) 0.85

Regulation of folate receptor internalization by protein kinase C alpha. Biochemistry (2009) 0.85

The interplay of AMP-activated protein kinase and androgen receptor in prostate cancer cells. J Cell Physiol (2014) 0.84

Enhancement of folate receptor alpha expression in tumor cells through the glucocorticoid receptor: a promising means to improved tumor detection and targeting. Cancer Res (2005) 0.83

Dual regulation of ets-activated gene expression by SP1. Gene (2003) 0.82

Expression and sub-cellular localization of the CCAAT/enhancer binding protein alpha in relation to postnatal development and malignancy of the prostate. Prostate (2008) 0.80

Penetration into solid tumor tissue of fluorescent latex microspheres: a mimic of liposome particles. Anticancer Res (2004) 0.80

mRNA instability in the nucleus due to a novel open reading frame element is a major determinant of the narrow tissue specificity of folate receptor alpha. Mol Cell Biol (2003) 0.79

Glucocorticoid receptor status is a principal determinant of variability in the sensitivity of non-small-cell lung cancer cells to pemetrexed. J Thorac Oncol (2014) 0.78

Androgen activation of the folate receptor α gene through partial tethering of the androgen receptor by C/EBPα. J Steroid Biochem Mol Biol (2010) 0.77

Analysis of folate binding protein N-linked glycans by mass spectrometry. J Proteome Res (2012) 0.76

Practical synthesis of a chromene analog for use as a retinoic acid receptor alpha antagonist lead compound. Eur J Med Chem (2013) 0.75