Stephen J Kron

Author PubWeight™ 60.65‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Binding of chromatin-modifying activities to phosphorylated histone H2A at DNA damage sites. Mol Cell 2004 4.17
2 Peptide chips for the quantitative evaluation of protein kinase activity. Nat Biotechnol 2002 3.05
3 Role of Dot1-dependent histone H3 methylation in G1 and S phase DNA damage checkpoint functions of Rad9. Mol Cell Biol 2005 2.48
4 Science education. Educating future scientists. Science 2003 1.97
5 Synthesis enables identification of the cellular target of leucascandrolide A and neopeltolide. Nat Chem Biol 2008 1.83
6 Histone H2AX phosphorylation as a predictor of radiosensitivity and target for radiotherapy. J Biol Chem 2003 1.79
7 NuA4 subunit Yng2 function in intra-S-phase DNA damage response. Mol Cell Biol 2002 1.51
8 Yeast G1 DNA damage checkpoint regulation by H2A phosphorylation is independent of chromatin remodeling. Proc Natl Acad Sci U S A 2006 1.32
9 Sensing, signalling and integrating physical processes during Saccharomyces cerevisiae invasive and filamentous growth. Microbiology 2002 1.32
10 CDK-dependent Hsp70 Phosphorylation controls G1 cyclin abundance and cell-cycle progression. Cell 2012 1.29
11 Poly(ADP-ribose) polymerase inhibitor induces accelerated senescence in irradiated breast cancer cells and tumors. Cancer Res 2010 1.22
12 Epigenetic modifications in double-strand break DNA damage signaling and repair. Clin Cancer Res 2010 1.18
13 Asynchronous cell cycle and asymmetric vacuolar inheritance in true hyphae of Candida albicans. Eukaryot Cell 2003 1.18
14 Bcl-x(L) complements Saccharomyces cerevisiae genes that facilitate the switch from glycolytic to oxidative metabolism. J Biol Chem 2002 1.16
15 Yeast cell death during DNA damage arrest is independent of caspase or reactive oxygen species. J Cell Biol 2004 1.11
16 Response of human prostate cancer cells and tumors to combining PARP inhibition with ionizing radiation. Mol Cancer Ther 2011 1.08
17 Depression of Saccharomyces cerevisiae invasive growth on non-glucose carbon sources requires the Snf1 kinase. Mol Microbiol 2002 1.07
18 Robust G1 checkpoint arrest in budding yeast: dependence on DNA damage signaling and repair. J Cell Sci 2002 1.06
19 Marker-fusion PCR for one-step mutagenesis of essential genes in yeast. Yeast 2002 1.01
20 CDK Pho85 targets CDK inhibitor Sic1 to relieve yeast G1 checkpoint arrest after DNA damage. Nat Struct Mol Biol 2006 1.00
21 A pairwise chemical genetic screen identifies new inhibitors of glucose transport. Chem Biol 2011 0.99
22 Peptide reporters of kinase activity in whole cell lysates. Biopolymers 2010 0.98
23 Relevance and irrelevance of DNA damage response to radiotherapy. DNA Repair (Amst) 2004 0.97
24 Investigating quantitation of phosphorylation using MALDI-TOF mass spectrometry. J Mass Spectrom 2008 0.97
25 Protein-acrylamide copolymer hydrogels for array-based detection of tyrosine kinase activity from cell lysates. Biomacromolecules 2005 0.96
26 A solid-phase Bcr-Abl kinase assay in 96-well hydrogel plates. Anal Biochem 2007 0.96
27 Radiation-inducible immunotherapy for cancer: senescent tumor cells as a cancer vaccine. Mol Ther 2012 0.92
28 Use of protein-acrylamide copolymer hydrogels for measuring protein concentration and activity. Anal Biochem 2004 0.89
29 A bead-based activity screen for small-molecule inhibitors of signal transduction in chronic myelogenous leukemia cells. Mol Cancer Ther 2010 0.87
30 An essential function of yeast cyclin-dependent kinase Cdc28 maintains chromosome stability. J Biol Chem 2002 0.87
31 Photocleavable peptide hydrogel arrays for MALDI-TOF analysis of kinase activity. Analyst 2006 0.86
32 Assaying Bcr-Abl kinase activity and inhibition in whole cell extracts by phosphorylation of substrates immobilized on agarose beads. Anal Biochem 2005 0.86
33 A magnetic bead-based protein kinase assay with dual detection techniques. Anal Biochem 2010 0.84
34 Quantifying the sensitivities of EGF receptor (EGFR) tyrosine kinase inhibitors in drug resistant non-small cell lung cancer (NSCLC) cells using hydrogel-based peptide array. Biosens Bioelectron 2010 0.84
35 Dissection of Rad9 BRCT domain function in the mitotic checkpoint response to telomere uncapping. DNA Repair (Amst) 2009 0.83
36 Cellular response to DNA damage. Ann N Y Acad Sci 2005 0.82
37 Non-catalytic function for ATR in the checkpoint response. Cell Cycle 2007 0.82
38 Optimizing thiophosphorylation in the presence of competing phosphorylation with MALDI-TOF-MS detection. J Proteome Res 2005 0.81
39 Rapid validation of Mascot search results via stable isotope labeling, pair picking, and deconvolution of fragmentation patterns. Mol Cell Proteomics 2009 0.81
40 Phosphoprotein profiling by PA-GeLC-MS/MS. J Proteome Res 2008 0.81
41 Control of the yeast cell cycle with a photocleavable alpha-factor analogue. Angew Chem Int Ed Engl 2006 0.81
42 Cell treatment and lysis in 96-well filter-bottom plates for screening Bcr-Abl activity and inhibition in whole-cell extracts. J Biomol Screen 2010 0.79
43 Design and implementation of algorithms for focus automation in digital imaging time-lapse microscopy. Cytometry 2002 0.79
44 Kinase activation in circulating cells: opportunities for biomarkers for diagnosis and therapeutic monitoring. Expert Opin Med Diagn 2008 0.78
45 Photocleavable peptide-oligonucleotide conjugates for protein kinase assays by MALDI-TOF MS. Mol Biosyst 2012 0.78
46 Monitoring changes in the subcellular location of proteins in S. cerevisiae. Methods Mol Biol 2004 0.78
47 Properties of resistant cells generated from lung cancer cell lines treated with EGFR inhibitors. BMC Cancer 2012 0.77
48 DNA resection proteins Sgs1 and Exo1 are required for G1 checkpoint activation in budding yeast. DNA Repair (Amst) 2013 0.77
49 Annotator: postprocessing software for generating function-based signatures from quantitative mass spectrometry. J Proteome Res 2012 0.76
50 The yin and yang of cyclin control by nutrients. Cell Cycle 2013 0.76
51 Photocleavable peptide-conjugated magnetic beads for protein kinase assays by MALDI-TOF MS. Bioconjug Chem 2010 0.76
52 DNA-directed assembly of antibody-fluorophore conjugates for quantitative multiparametric flow cytometry. Chembiochem 2013 0.75
53 Morphogenesis signaling components influence cell cycle regulation by cyclin dependent kinase. Cell Div 2009 0.75
54 A phosphorylation-independent role for the yeast cyclin-dependent kinase activating kinase Cak1. Gene 2009 0.75
55 Activity assay of epidermal growth factor receptor tyrosine kinase inhibitors in triple-negative breast cancer cells using peptide-conjugated magnetic beads. Assay Drug Dev Technol 2012 0.75