|
1
|
Perioperative chemotherapy with FOLFOX4 and surgery versus surgery alone for resectable liver metastases from colorectal cancer (EORTC Intergroup trial 40983): a randomised controlled trial.
|
Lancet
|
2008
|
9.92
|
|
2
|
Negative feedback loop of Wnt signaling through upregulation of conductin/axin2 in colorectal and liver tumors.
|
Mol Cell Biol
|
2002
|
8.60
|
|
3
|
Intrahepatic arterial versus intravenous fluorouracil and folinic acid for colorectal cancer liver metastases: a multicentre randomised trial.
|
Lancet
|
2003
|
3.89
|
|
4
|
MACC1, a newly identified key regulator of HGF-MET signaling, predicts colon cancer metastasis.
|
Nat Med
|
2008
|
3.00
|
|
5
|
Perioperative FOLFOX4 chemotherapy and surgery versus surgery alone for resectable liver metastases from colorectal cancer (EORTC 40983): long-term results of a randomised, controlled, phase 3 trial.
|
Lancet Oncol
|
2013
|
2.94
|
|
6
|
Neoadjuvant chemotherapy compared with surgery alone for locally advanced cancer of the stomach and cardia: European Organisation for Research and Treatment of Cancer randomized trial 40954.
|
J Clin Oncol
|
2010
|
2.66
|
|
7
|
Sensitive detection of colorectal cancer in peripheral blood by septin 9 DNA methylation assay.
|
PLoS One
|
2008
|
2.46
|
|
8
|
Predictive factors for the benefit of perioperative FOLFOX for resectable liver metastasis in colorectal cancer patients (EORTC Intergroup Trial 40983).
|
Ann Surg
|
2012
|
2.43
|
|
9
|
Novel effect of antihelminthic Niclosamide on S100A4-mediated metastatic progression in colon cancer.
|
J Natl Cancer Inst
|
2011
|
2.11
|
|
10
|
Dynamic expression profile of p21WAF1/CIP1 and Ki-67 predicts survival in rectal carcinoma treated with preoperative radiochemotherapy.
|
J Clin Oncol
|
2003
|
2.04
|
|
11
|
Sentinel lymph node biopsy in colon cancer: a prospective multicenter trial.
|
Ann Surg
|
2007
|
1.79
|
|
12
|
The metastasis-associated gene S100A4 is a novel target of beta-catenin/T-cell factor signaling in colon cancer.
|
Gastroenterology
|
2006
|
1.73
|
|
13
|
S100A4-induced cell motility and metastasis is restricted by the Wnt/β-catenin pathway inhibitor calcimycin in colon cancer cells.
|
Mol Biol Cell
|
2011
|
1.71
|
|
14
|
Identification of brain- and bone-specific breast cancer metastasis genes.
|
Cancer Lett
|
2008
|
1.54
|
|
15
|
Time-domain optical mammography: initial clinical results on detection and characterization of breast tumors.
|
Appl Opt
|
2003
|
1.53
|
|
16
|
A colorectal cancer expression profile that includes transforming growth factor beta inhibitor BAMBI predicts metastatic potential.
|
Gastroenterology
|
2009
|
1.52
|
|
17
|
Vascular endothelial growth factor-D and its receptor VEGFR-3: two novel independent prognostic markers in gastric adenocarcinoma.
|
J Clin Oncol
|
2005
|
1.49
|
|
18
|
Cell surface alpha 2,6 sialylation affects adhesion of breast carcinoma cells.
|
Exp Cell Res
|
2002
|
1.48
|
|
19
|
Efficacy of different technical procedures for sentinel lymph node biopsy in gastric cancer staging.
|
Ann Surg Oncol
|
2007
|
1.46
|
|
20
|
Response to preoperative short-course radiotherapy in locally advanced rectal cancer: value of f-fluorodeoxyglucose positron emission tomography.
|
Onkologie
|
2008
|
1.46
|
|
21
|
Identification of early molecular markers for breast cancer.
|
Mol Cancer
|
2011
|
1.45
|
|
22
|
Treatment of thoracic anastomotic leaks after esophagectomy with self-expanding plastic stents.
|
Ann Surg
|
2004
|
1.35
|
|
23
|
Clinical, biological, and molecular aspects of metastasis in colorectal cancer.
|
Recent Results Cancer Res
|
2007
|
1.28
|
|
24
|
Time-domain scanning optical mammography: II. Optical properties and tissue parameters of 87 carcinomas.
|
Phys Med Biol
|
2005
|
1.26
|
|
25
|
Time-domain scanning optical mammography: I. Recording and assessment of mammograms of 154 patients.
|
Phys Med Biol
|
2005
|
1.26
|
|
26
|
Integrative marker analysis allows risk assessment for metastasis in stage II colon cancer.
|
Ann Surg
|
2012
|
1.25
|
|
27
|
Construct validity testing of a laparoscopic surgery simulator (Lap Mentor): evaluation of surgical skill with a virtual laparoscopic training simulator.
|
Surg Endosc
|
2007
|
1.24
|
|
28
|
ST18 is a breast cancer tumor suppressor gene at human chromosome 8q11.2.
|
Oncogene
|
2004
|
1.19
|
|
29
|
Long-term morbidity of patients with early breast cancer after sentinel lymph node biopsy compared to axillary lymph node dissection.
|
J Surg Oncol
|
2006
|
1.15
|
|
30
|
Late-fluorescence mammography assesses tumor capillary permeability and differentiates malignant from benign lesions.
|
Opt Express
|
2009
|
1.13
|
|
31
|
Identification of Y-box binding protein 1 as a core regulator of MEK/ERK pathway-dependent gene signatures in colorectal cancer cells.
|
PLoS Genet
|
2010
|
1.12
|
|
32
|
Scanning time-domain optical mammography: detection and characterization of breast tumors in vivo.
|
Technol Cancer Res Treat
|
2005
|
1.10
|
|
33
|
Influence of genetic variations in TLR4 and TIRAP/Mal on the course of sepsis and pneumonia and cytokine release: an observational study in three cohorts.
|
Crit Care
|
2010
|
1.08
|
|
34
|
Sentinel node biopsy for the individualization of surgical strategy for cure of early-stage colon cancer.
|
Ann Surg Oncol
|
2009
|
1.08
|
|
35
|
Feasibility of navigated resection of liver tumors using multiplanar visualization of intraoperative 3-dimensional ultrasound data.
|
Ann Surg
|
2007
|
1.07
|
|
36
|
Gastric cancer surgery in elderly patients.
|
World J Surg
|
2006
|
1.07
|
|
37
|
Circulating MACC1 transcripts in colorectal cancer patient plasma predict metastasis and prognosis.
|
PLoS One
|
2012
|
1.06
|
|
38
|
RAGE mediates S100A4-induced cell motility via MAPK/ERK and hypoxia signaling and is a prognostic biomarker for human colorectal cancer metastasis.
|
Oncotarget
|
2014
|
1.03
|
|
39
|
Identification of microsatellite instability and mismatch repair gene mutations in breast cancer cell lines.
|
Genes Chromosomes Cancer
|
2003
|
1.03
|
|
40
|
Intervening in β-catenin signaling by sulindac inhibits S100A4-dependent colon cancer metastasis.
|
Neoplasia
|
2011
|
1.02
|
|
41
|
Response prediction by FDG-PET after neoadjuvant radiochemotherapy and combined regional hyperthermia of rectal cancer: correlation with endorectal ultrasound and histopathology.
|
Eur J Nucl Med Mol Imaging
|
2004
|
1.01
|
|
42
|
Concentration and oxygen saturation of haemoglobin of 50 breast tumours determined by time-domain optical mammography.
|
Phys Med Biol
|
2004
|
1.00
|
|
43
|
Detection of lymph node micrometastases and isolated tumor cells in sentinel and nonsentinel lymph nodes of colon cancer patients.
|
World J Surg
|
2005
|
0.97
|
|
44
|
3D ultrasound-CT registration of the liver using combined landmark-intensity information.
|
Int J Comput Assist Radiol Surg
|
2008
|
0.97
|
|
45
|
Upgrade of an optical navigation system with a permanent electromagnetic position control: a first step towards "navigated control" for liver surgery.
|
J Hepatobiliary Pancreat Surg
|
2009
|
0.96
|
|
46
|
Diagnostic and prognostic value of metastasis inducer S100A4 transcripts in plasma of colon, rectal, and gastric cancer patients.
|
J Mol Diagn
|
2011
|
0.93
|
|
47
|
Promoter identification and transcriptional regulation of the metastasis gene MACC1 in colorectal cancer.
|
Mol Oncol
|
2013
|
0.92
|
|
48
|
In vivo imaging of colorectal cancer growth and metastasis by targeting MACC1 with shRNA in xenografted mice.
|
Clin Exp Metastasis
|
2012
|
0.92
|
|
49
|
De novo expression of EphA2 in osteosarcoma modulates activation of the mitogenic signalling pathway.
|
Histopathology
|
2010
|
0.92
|
|
50
|
Body mass index does not affect systematic D2 lymph node dissection and postoperative morbidity in gastric cancer patients.
|
Ann Surg Oncol
|
2003
|
0.90
|
|
51
|
Current status of gene therapy for cancer.
|
Curr Opin Oncol
|
2013
|
0.89
|
|
52
|
SNPs in the coding region of the metastasis-inducing gene MACC1 and clinical outcome in colorectal cancer.
|
Mol Cancer
|
2012
|
0.89
|
|
53
|
Correlation of visinin-like-protein-1 expression with clinicopathological features in squamous cell carcinoma of the esophagus.
|
Mol Carcinog
|
2006
|
0.88
|
|
54
|
Reconstruction of optical properties of phantom and breast lesion in vivo from paraxial scanning data.
|
Phys Med Biol
|
2005
|
0.87
|
|
55
|
Systemic shRNA mediated knock down of S100A4 in colorectal cancer xenografted mice reduces metastasis formation.
|
Oncotarget
|
2012
|
0.87
|
|
56
|
Quantification of optical properties of a breast tumor using random walk theory.
|
J Biomed Opt
|
2002
|
0.87
|
|
57
|
Performance of high quality minicircle DNA for in vitro and in vivo gene transfer.
|
Mol Biotechnol
|
2013
|
0.87
|
|
58
|
Non-physiological overexpression of the low density lipoprotein receptor (LDLr) gene in the liver induces pathological intracellular lipid and cholesterol storage.
|
J Gene Med
|
2004
|
0.87
|
|
59
|
Clinical relevance of sialyltransferases ST6GAL-I and ST3GAL-III in gastric cancer.
|
Oncology
|
2003
|
0.86
|
|
60
|
Evaluation of pathologic nipple discharge with ductoscopy.
|
J Am Coll Surg
|
2003
|
0.85
|
|
61
|
Stability analysis for long-term storage of naked DNA: impact on nonviral in vivo gene transfer.
|
Anal Biochem
|
2003
|
0.85
|
|
62
|
Technique and clinical consequences of sentinel lymph node biopsy in colorectal cancer.
|
Surg Oncol
|
2008
|
0.85
|
|
63
|
Genetic dissection of apoptosis and cell cycle control in response of colorectal cancer treated with preoperative radiochemotherapy.
|
BMC Cancer
|
2006
|
0.84
|
|
64
|
Pre- and postoperative cytokine release after in vitro whole blood lipopolysaccharide stimulation and frequent toll-like receptor 4 polymorphisms.
|
Shock
|
2006
|
0.84
|
|
65
|
HER2/neu DNA vaccination by intradermal gene delivery in a mouse tumor model: Gene gun is superior to jet injector in inducing CTL responses and protective immunity.
|
Oncoimmunology
|
2012
|
0.84
|
|
66
|
Palliation of malignant rectal obstruction with self-expanding metal stents.
|
Surgery
|
2005
|
0.83
|
|
67
|
Prognostic value of cytokeratin-positive bone marrow cells of gastric cancer patients.
|
Ann Surg Oncol
|
2007
|
0.83
|
|
68
|
Use of the nuclease inhibitor aurintricarboxylic acid (ATA) for improved non-viral intratumoral in vivo gene transfer by jet-injection.
|
J Gene Med
|
2005
|
0.82
|
|
69
|
Novel jet-injection technology for nonviral intratumoral gene transfer in patients with melanoma and breast cancer.
|
Clin Cancer Res
|
2008
|
0.82
|
|
70
|
Phantom phenomena in mastectomized patients and their relation to chronic and acute pre-mastectomy pain.
|
Pain
|
2004
|
0.81
|
|
71
|
YB-1 facilitates basal and 5-fluorouracil-inducible expression of the human major vault protein (MVP) gene.
|
Oncogene
|
2005
|
0.81
|
|
72
|
Is there additional information from laparoscopic ultrasound in tumor staging?
|
Dig Surg
|
2002
|
0.81
|
|
73
|
Preoperative short-course radiotherapy versus combined radiochemotherapy in locally advanced rectal cancer: a multi-centre prospectively randomised study of the Berlin Cancer Society.
|
BMC Cancer
|
2009
|
0.81
|
|
74
|
Pentoxifyllin attenuates the systemic inflammatory response induced during isolated limb perfusion with recombinant human tumor necrosis factor-alpha and melphalan.
|
Ann Surg Oncol
|
2003
|
0.81
|
|
75
|
Interactive telemedical applications in OP 2000 via satellite.
|
Biomed Tech (Berl)
|
2002
|
0.81
|
|
76
|
Loss of UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase (GNE) induces apoptotic processes in pancreatic carcinoma cells.
|
FASEB J
|
2011
|
0.81
|
|
77
|
Intraoperative ductoscopy in women undergoing surgery for breast cancer.
|
Surgery
|
2006
|
0.81
|
|
78
|
Ductoscopy and intraductal vacuum assisted biopsy in women with pathologic nipple discharge.
|
Breast Cancer Res Treat
|
2006
|
0.81
|
|
79
|
Use of the human MDR1 promoter for heat-inducible expression of therapeutic genes.
|
Int J Cancer
|
2002
|
0.80
|
|
80
|
Expression of the protein phosphatase 1 inhibitor KEPI is downregulated in breast cancer cell lines and tissues and involved in the regulation of the tumor suppressor EGR1 via the MEK-ERK pathway.
|
Biol Chem
|
2007
|
0.80
|
|
81
|
Mutation analysis and mRNA expression of trail-receptors in human breast cancer.
|
Int J Cancer
|
2002
|
0.80
|
|
82
|
Practice and effectiveness of outpatient psycho-oncological counseling for cancer patients.
|
J Cancer
|
2010
|
0.79
|
|
83
|
A multichannel time-domain scanning fluorescence mammograph: performance assessment and first in vivo results.
|
Rev Sci Instrum
|
2011
|
0.79
|
|
84
|
Activation of the CMV-IE promoter by hyperthermia in vitro and in vivo: biphasic heat induction of cytosine deaminase suicide gene expression.
|
Mol Biotechnol
|
2010
|
0.79
|
|
85
|
Intratumoral low-volume jet-injection for efficient nonviral gene transfer.
|
Mol Biotechnol
|
2002
|
0.79
|
|
86
|
Interactive telemedicine as a tool to avoid a digital divide in the world.
|
Stud Health Technol Inform
|
2004
|
0.79
|
|
87
|
Low-volume jet injection for efficient nonviral in vivo gene transfer.
|
Mol Biotechnol
|
2004
|
0.78
|
|
88
|
Prospective comparison of transcutaneous 3-dimensional US cholangiography, magnetic resonance cholangiography, and direct cholangiography in the evaluation of malignant biliary obstruction.
|
Gastrointest Endosc
|
2003
|
0.78
|
|
89
|
New trends in the virtualization of hospitals--tools for global e-Health.
|
Stud Health Technol Inform
|
2006
|
0.78
|
|
90
|
Surgery, surgical education and surgical diagnostic procedures in the digital era.
|
Med Sci Monit
|
2003
|
0.78
|
|
91
|
The course of gastric cancer following surgery is associated with genetic variations of the interleukin-1 receptor antagonist and interleukin-1β.
|
Gastric Cancer
|
2014
|
0.77
|
|
92
|
Heat-inducible in vivo gene therapy of colon carcinoma by human mdr1 promoter-regulated tumor necrosis factor-alpha expression.
|
Mol Cancer Ther
|
2007
|
0.77
|
|
93
|
[Treatment of gastric cancer].
|
Onkologie
|
2008
|
0.77
|
|
94
|
SV40 large T antigen-transformed human primary normal and cancerous mammary epithelial cells are phenotypically similar but can be distinguished in 3D culture with selection medium.
|
Int J Cancer
|
2008
|
0.77
|
|
95
|
Intratumoral dispersion, retention, systemic biodistribution, and clearance of a small-size tumor necrosis factor-α-expressing MIDGE vector after nonviral in vivo jet-injection gene transfer.
|
Hum Gene Ther Methods
|
2012
|
0.77
|
|
96
|
Ductoscopic biopsy of papillary tumors in women with nipple discharge.
|
Ann Surg
|
2007
|
0.77
|
|
97
|
Nonviral jet-injection gene transfer for efficient in vivo cytosine deaminase suicide gene therapy of colon carcinoma.
|
Mol Ther
|
2005
|
0.76
|
|
98
|
Can the presence of micrometastases in patients with colorectal cancer be used to help guide treatment?
|
Nat Clin Pract Gastroenterol Hepatol
|
2008
|
0.75
|
|
99
|
Nonviral jet-injection technology for intratumoral in vivo gene transfer of naked DNA.
|
Methods Mol Biol
|
2009
|
0.75
|
|
100
|
[Multimodality treatment for colorectal cancer].
|
Onkologie
|
2008
|
0.75
|
|
101
|
[Diagnosis of tumors of the small intestine with the aid of CT contrast enema. Sellink CT technique evaluated in 63 patients].
|
Rontgenpraxis
|
2002
|
0.75
|
|
102
|
Current status of sentinel lymph node biopsy in adenocarcinoma of the distal esophagus, gastric cardia, and proximal stomach.
|
Recent Results Cancer Res
|
2010
|
0.75
|
|
103
|
Ductoscopy of intraductal neoplasia of the breast.
|
Recent Results Cancer Res
|
2009
|
0.75
|
|
104
|
Therapeutic potential of CAMPATH-1H in skeletal tumours.
|
Histopathology
|
2010
|
0.75
|
|
105
|
Network design for telemedicine--e-health using satellite technology.
|
Stud Health Technol Inform
|
2008
|
0.75
|
|
106
|
Virtual hospital and digital medicine--why is the GRID needed?
|
Stud Health Technol Inform
|
2006
|
0.75
|
|
107
|
Time for progress.
|
Onkologie
|
2004
|
0.75
|