Published in Am J Physiol Renal Physiol on September 20, 2005
The solute carrier 6 family of transporters. Br J Pharmacol (2012) 1.14
Metabolomics reveals attenuation of the SLC6A20 kidney transporter in nonhuman primate and mouse models of type 2 diabetes mellitus. J Biol Chem (2011) 1.06
Kidney amino acid transport. Pflugers Arch (2009) 1.03
Impaired nutrient signaling and body weight control in a Na+ neutral amino acid cotransporter (Slc6a19)-deficient mouse. J Biol Chem (2011) 0.97
Synergy and specificity of two Na+-aromatic amino acid symporters in the model alimentary canal of mosquito larvae. J Exp Biol (2008) 0.92
Proximal tubule function and response to acidosis. Clin J Am Soc Nephrol (2013) 0.91
Orphan transporter SLC6A18 is renal neutral amino acid transporter B0AT3. J Biol Chem (2009) 0.87
Intestinal peptidases form functional complexes with the neutral amino acid transporter B(0)AT1. Biochem J (2012) 0.84
Differential axial localization along the mouse brain vascular tree of luminal sodium-dependent glutamine transporters Snat1 and Snat3. J Cereb Blood Flow Metab (2011) 0.83
Amino acids regulate transgene expression in MDCK cells. PLoS One (2014) 0.78
Myosin 1b Regulates Amino Acid Transport by Associating Transporters with the Apical Plasma Membrane of Kidney Cells. PLoS One (2015) 0.78
Ammonia Transporters and Their Role in Acid-Base Balance. Physiol Rev (2017) 0.77
An SLC6 transporter of the novel B(0,)- system aids in absorption and detection of nutrient amino acids in Caenorhabditis elegans. J Exp Biol (2013) 0.77
pH-responsive, gluconeogenic renal epithelial LLC-PK1-FBPase+cells: a versatile in vitro model to study renal proximal tubule metabolism and function. Am J Physiol Renal Physiol (2014) 0.77
Intestinal B(0)AT1 (SLC6A19) and PEPT1 (SLC15A1) mRNA levels in European sea bass (Dicentrarchus labrax) reared in fresh water and fed fish and plant protein sources. J Nutr Sci (2015) 0.76
Genetic Targeting of Arginase-II in Mouse Prevents Renal Oxidative Stress and Inflammation in Diet-Induced Obesity. Front Physiol (2016) 0.75
Expression and regulation of the neutral amino acid transporter B0AT1 in rat small intestine. PLoS One (2017) 0.75
Structural asymmetry of AcrB trimer suggests a peristaltic pump mechanism. Science (2006) 4.21
Diarylquinolines target subunit c of mycobacterial ATP synthase. Nat Chem Biol (2007) 2.83
CATs and HATs: the SLC7 family of amino acid transporters. Pflugers Arch (2003) 2.69
ACE2 links amino acid malnutrition to microbial ecology and intestinal inflammation. Nature (2012) 2.53
Impaired renal Na(+) retention in the sgk1-knockout mouse. J Clin Invest (2002) 2.47
Enhanced passive Ca2+ reabsorption and reduced Mg2+ channel abundance explains thiazide-induced hypocalciuria and hypomagnesemia. J Clin Invest (2005) 2.14
A Golgi-associated PDZ domain protein modulates cystic fibrosis transmembrane regulator plasma membrane expression. J Biol Chem (2001) 1.97
The calcium-sensing receptor promotes urinary acidification to prevent nephrolithiasis. J Am Soc Nephrol (2009) 1.85
Role of Sgk1 in salt and potassium homeostasis. Am J Physiol Regul Integr Comp Physiol (2005) 1.81
Engineered disulfide bonds support the functional rotation mechanism of multidrug efflux pump AcrB. Nat Struct Mol Biol (2008) 1.81
Rapid dephosphorylation of the renal sodium chloride cotransporter in response to oral potassium intake in mice. Kidney Int (2013) 1.80
Calcium-pump inhibitors induce functional surface expression of Delta F508-CFTR protein in cystic fibrosis epithelial cells. Nat Med (2002) 1.75
Bile acids trigger cholemic nephropathy in common bile-duct-ligated mice. Hepatology (2013) 1.71
Characterization of renal interstitial fibroblast-specific protein 1/S100A4-positive cells in healthy and inflamed rodent kidneys. Histochem Cell Biol (2005) 1.69
α-Ketoglutarate regulates acid-base balance through an intrarenal paracrine mechanism. J Clin Invest (2013) 1.66
Transport of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loop. Proc Natl Acad Sci U S A (2012) 1.66
Activation of system L heterodimeric amino acid exchangers by intracellular substrates. EMBO J (2002) 1.66
PDZK1: I. a major scaffolder in brush borders of proximal tubular cells. Kidney Int (2003) 1.64
Collecting duct-specific gene inactivation of alphaENaC in the mouse kidney does not impair sodium and potassium balance. J Clin Invest (2003) 1.64
A role for Rhesus factor Rhcg in renal ammonium excretion and male fertility. Nature (2008) 1.61
Proximal tubular epithelial cells are generated by division of differentiated cells in the healthy kidney. Am J Physiol Cell Physiol (2006) 1.58
Aldosterone-dependent and -independent regulation of the epithelial sodium channel (ENaC) in mouse distal nephron. Am J Physiol Renal Physiol (2012) 1.58
SPECT and PET amino acid tracer influx via system L (h4F2hc-hLAT1) and its transstimulation. J Nucl Med (2004) 1.55
The B1-subunit of the H(+) ATPase is required for maximal urinary acidification. Proc Natl Acad Sci U S A (2005) 1.51
Impairment of sodium balance in mice deficient in renal principal cell mineralocorticoid receptor. J Am Soc Nephrol (2007) 1.51
Mineralocorticoid versus glucocorticoid receptor occupancy mediating aldosterone-stimulated sodium transport in a novel renal cell line. J Am Soc Nephrol (2005) 1.50
Sodium and potassium handling by the aldosterone-sensitive distal nephron: the pivotal role of the distal and connecting tubule. Am J Physiol Renal Physiol (2004) 1.46
Heteromeric KCNE2/KCNQ1 potassium channels in the luminal membrane of gastric parietal cells. J Physiol (2004) 1.46
Mutations in SLC6A19, encoding B0AT1, cause Hartnup disorder. Nat Genet (2004) 1.45
cAMP stimulates apical V-ATPase accumulation, microvillar elongation, and proton extrusion in kidney collecting duct A-intercalated cells. Am J Physiol Renal Physiol (2010) 1.40
Proximal renal tubular acidosis in TASK2 K+ channel-deficient mice reveals a mechanism for stabilizing bicarbonate transport. Proc Natl Acad Sci U S A (2004) 1.40
Decreased bone density and increased phosphaturia in gene-targeted mice lacking functional serum- and glucocorticoid-inducible kinase 3. Kidney Int (2011) 1.40
Parathyroid hormone treatment induces dissociation of type IIa Na+-P(i) cotransporter-Na+/H+ exchanger regulatory factor-1 complexes. Am J Physiol Cell Physiol (2005) 1.36
Mouse model of type II Bartter's syndrome. II. Altered expression of renal sodium- and water-transporting proteins. Am J Physiol Renal Physiol (2008) 1.36
PDZK1: II. an anchoring site for the PKA-binding protein D-AKAP2 in renal proximal tubular cells. Kidney Int (2003) 1.35
Human cortical distal nephron: distribution of electrolyte and water transport pathways. J Am Soc Nephrol (2002) 1.32
Early aldosterone-induced gene product regulates the epithelial sodium channel by deubiquitylation. J Am Soc Nephrol (2007) 1.31
Endothelial mineralocorticoid receptor activation mediates endothelial dysfunction in diet-induced obesity. Eur Heart J (2013) 1.31
Regulation of sodium-proton exchanger isoform 3 (NHE3) by PKA and exchange protein directly activated by cAMP (EPAC). Proc Natl Acad Sci U S A (2006) 1.30
Programmed death 1 protects from fatal circulatory failure during systemic virus infection of mice. J Exp Med (2012) 1.29
Essential role for collectrin in renal amino acid transport. Nature (2006) 1.26
Cell-surface expression of the channel activating protease xCAP-1 is required for activation of ENaC in the Xenopus oocyte. J Am Soc Nephrol (2002) 1.25
Regulation of intestinal phosphate transport. I. Segmental expression and adaptation to low-P(i) diet of the type IIb Na(+)-P(i) cotransporter in mouse small intestine. Am J Physiol Gastrointest Liver Physiol (2005) 1.25
Thiazide-induced hypocalciuria is accompanied by a decreased expression of Ca2+ transport proteins in kidney. Kidney Int (2003) 1.22
Impaired regulation of renal K+ elimination in the sgk1-knockout mouse. J Am Soc Nephrol (2004) 1.21
CNNM2, encoding a basolateral protein required for renal Mg2+ handling, is mutated in dominant hypomagnesemia. Am J Hum Genet (2011) 1.20
Pendrin regulation in mouse kidney primarily is chloride-dependent. J Am Soc Nephrol (2006) 1.19
Secreted Klotho and FGF23 in chronic kidney disease Stage 1 to 5: a sequence suggested from a cross-sectional study. Nephrol Dial Transplant (2012) 1.18
Specific amino acids inhibit food intake via the area postrema or vagal afferents. J Physiol (2013) 1.18
Decreased ENaC expression compensates the increased NCC activity following inactivation of the kidney-specific isoform of WNK1 and prevents hypertension. Proc Natl Acad Sci U S A (2010) 1.18
Distal renal tubular acidosis in mice lacking the AE1 (band3) Cl-/HCO3- exchanger (slc4a1). J Am Soc Nephrol (2007) 1.18
Crucial role of Asp408 in the proton translocation pathway of multidrug transporter AcrB: evidence from site-directed mutagenesis and carbodiimide labeling. Biochemistry (2009) 1.17
Dysfunction of the epithelial sodium channel expressed in the kidney of a mouse model for Liddle syndrome. J Am Soc Nephrol (2003) 1.16
Compensatory membrane expression of the V-ATPase B2 subunit isoform in renal medullary intercalated cells of B1-deficient mice. Am J Physiol Renal Physiol (2007) 1.16
Nongenomic stimulation of vacuolar H+-ATPases in intercalated renal tubule cells by aldosterone. Proc Natl Acad Sci U S A (2004) 1.15
Genome-wide gene expression profiling reveals renal genes regulated during metabolic acidosis. Physiol Genomics (2007) 1.14
Mercuric conjugates of cysteine are transported by the amino acid transporter system b(0,+): implications of molecular mimicry. J Am Soc Nephrol (2004) 1.13
Renal β-intercalated cells maintain body fluid and electrolyte balance. J Clin Invest (2013) 1.13
Renal tubular NEDD4-2 deficiency causes NCC-mediated salt-dependent hypertension. J Clin Invest (2013) 1.13
Basolateral aromatic amino acid transporter TAT1 (Slc16a10) functions as an efflux pathway. J Cell Physiol (2006) 1.12
Activation of dopamine D1-like receptors induces acute internalization of the renal Na+/phosphate cotransporter NaPi-IIa in mouse kidney and OK cells. Am J Physiol Renal Physiol (2004) 1.11
In vivo nuclear translocation of mineralocorticoid and glucocorticoid receptors in rat kidney: differential effect of corticosteroids along the distal tubule. Am J Physiol Renal Physiol (2010) 1.10
The AcrB efflux pump: conformational cycling and peristalsis lead to multidrug resistance. Curr Drug Targets (2008) 1.09
Aldosterone-induced serum and glucocorticoid-induced kinase 1 expression is accompanied by Nedd4-2 phosphorylation and increased Na+ transport in cortical collecting duct cells. J Am Soc Nephrol (2005) 1.09
The tegument of the human parasitic worm Schistosoma mansoni as an excretory organ: the surface aquaporin SmAQP is a lactate transporter. PLoS One (2010) 1.09
Expression and regulation of the renal Na/phosphate cotransporter NaPi-IIa in a mouse model deficient for the PDZ protein PDZK1. Pflugers Arch (2004) 1.08
Angiotensin II stimulates vacuolar H+ -ATPase activity in renal acid-secretory intercalated cells from the outer medullary collecting duct. J Am Soc Nephrol (2007) 1.07
Progesterone down-regulates the open probability of the amiloride-sensitive epithelial sodium channel via a Nedd4-2-dependent mechanism. J Biol Chem (2005) 1.07
Thiazide effects and adverse effects: insights from molecular genetics. Hypertension (2009) 1.07
Mechanisms of pH-gradient driven transport mediated by organic anion polypeptide transporters. Am J Physiol Cell Physiol (2009) 1.06
Intestinal and renal adaptation to a low-Pi diet of type II NaPi cotransporters in vitamin D receptor- and 1alphaOHase-deficient mice. Am J Physiol Cell Physiol (2005) 1.05
Roux-en-Y gastric bypass surgery reduces bone mineral density and induces metabolic acidosis in rats. Am J Physiol Regul Integr Comp Physiol (2013) 1.04
Hyperaldosteronemia and activation of the epithelial sodium channel are not required for sodium retention in puromycin-induced nephrosis. J Am Soc Nephrol (2005) 1.04
Deubiquitylation regulates activation and proteolytic cleavage of ENaC. J Am Soc Nephrol (2008) 1.03
Kidney amino acid transport. Pflugers Arch (2009) 1.03
Renal expression of parvalbumin is critical for NaCl handling and response to diuretics. Proc Natl Acad Sci U S A (2007) 1.03
Tissue-specific amino acid transporter partners ACE2 and collectrin differentially interact with hartnup mutations. Gastroenterology (2008) 1.03
Impact of Nedd4 proteins and serum and glucocorticoid-induced kinases on epithelial Na+ transport in the distal nephron. J Am Soc Nephrol (2005) 1.03
The calcineurin inhibitor FK506 (tacrolimus) is associated with transient metabolic acidosis and altered expression of renal acid-base transport proteins. Am J Physiol Renal Physiol (2009) 1.01
Defective coupling of apical PTH receptors to phospholipase C prevents internalization of the Na+-phosphate cotransporter NaPi-IIa in Nherf1-deficient mice. Am J Physiol Cell Physiol (2006) 1.01
Apical heterodimeric cystine and cationic amino acid transporter expressed in MDCK cells. Am J Physiol Renal Physiol (2002) 1.01
Regulation of the glutamine transporter SN1 by extracellular pH and intracellular sodium ions. J Physiol (2002) 1.01
Potassium restriction, high protein intake, and metabolic acidosis increase expression of the glutamine transporter SNAT3 (Slc38a3) in mouse kidney. Am J Physiol Renal Physiol (2009) 1.01
Soluble klotho and autosomal dominant polycystic kidney disease. Clin J Am Soc Nephrol (2011) 1.00
Pendrin in the mouse kidney is primarily regulated by Cl- excretion but also by systemic metabolic acidosis. Am J Physiol Cell Physiol (2008) 1.00