Published in Ther Drug Monit on October 01, 2005
In vivo administration of a JAK3 inhibitor during acute SIV infection leads to significant increases in viral load during chronic infection. PLoS Pathog (2014) 0.85
In vivo administration of a JAK3 inhibitor to chronically siv infected rhesus macaques leads to NK cell depletion associated with transient modest increase in viral loads. PLoS One (2013) 0.79
Prevention of organ allograft rejection by a specific Janus kinase 3 inhibitor. Science (2003) 3.19
Transplantation for idiopathic pulmonary arterial hypertension: improvement in the lung allocation score era. Circulation (2013) 2.87
Elevated tricuspid regurgitant jet velocity in children and adolescents with sickle cell disease: association with hemolysis and hemoglobin oxygen desaturation. Haematologica (2009) 2.20
Clinical recognition of Al type amyloidosis of the luminal gastrointestinal tract. Clin Gastroenterol Hepatol (2007) 1.88
Dexmedetomidine and the reduction of postoperative delirium after cardiac surgery. Psychosomatics (2009) 1.86
Translocation (11;15;19): a highly specific chromosome rearrangement associated with poorly differentiated thymic carcinoma in young patients. Am J Clin Oncol (2003) 1.80
A recombinant polypeptide extends the in vivo half-life of peptides and proteins in a tunable manner. Nat Biotechnol (2009) 1.77
A new modality for immunosuppression: targeting the JAK/STAT pathway. Nat Rev Drug Discov (2004) 1.73
Brain injury and development in newborns with critical congenital heart disease. Neurology (2013) 1.61
Discovery of CP-690,550: a potent and selective Janus kinase (JAK) inhibitor for the treatment of autoimmune diseases and organ transplant rejection. J Med Chem (2010) 1.55
Double-blind, placebo-controlled, dose-escalation study to evaluate the pharmacologic effect of CP-690,550 in patients with psoriasis. J Invest Dermatol (2009) 1.54
Metabolism and excretion of erlotinib, a small molecule inhibitor of epidermal growth factor receptor tyrosine kinase, in healthy male volunteers. Drug Metab Dispos (2005) 1.48
PI3K-δ and PI3K-γ inhibition by IPI-145 abrogates immune responses and suppresses activity in autoimmune and inflammatory disease models. Chem Biol (2013) 1.47
Astrocytes secrete exosomes enriched with proapoptotic ceramide and prostate apoptosis response 4 (PAR-4): potential mechanism of apoptosis induction in Alzheimer disease (AD). J Biol Chem (2012) 1.41
Internet use and loneliness in older adults. Cyberpsychol Behav (2008) 1.40
Celiac disease unmasked after pancreaticoduodenectomy. JPEN J Parenter Enteral Nutr (2005) 1.39
Discovery of a potent and selective EGFR inhibitor (AZD9291) of both sensitizing and T790M resistance mutations that spares the wild type form of the receptor. J Med Chem (2014) 1.36
Regression of severe pulmonary arteriovenous malformations after Fontan revision and "hepatic factor" rerouting. Ann Thorac Surg (2004) 1.26
Can the semiempirical PM3 scheme describe iron-containing bioinorganic molecules? J Comput Chem (2006) 1.24
‘Off your Face(book)’: alcohol in online social identity construction and its relation to problem drinking in university students. Drug Alcohol Rev (2012) 1.23
Prospective echocardiography assessment of pulmonary hypertension and its potential etiologies in children with sickle cell disease. Am J Cardiol (2009) 1.22
An interface for direct analysis of (14)c in nonvolatile samples by accelerator mass spectrometry. Anal Chem (2004) 1.18
Unusual presentations of aorto-enteric fistula. Gastrointest Endosc (2004) 1.17
Relationship of erythropoietin, fetal hemoglobin, and hydroxyurea treatment to tricuspid regurgitation velocity in children with sickle cell disease. Blood (2009) 1.16
Xenobiotic-metabolizing enzymes in human lung. Curr Drug Metab (2006) 1.13
Meta-analysis of 2040 sickle cell anemia patients: BCL11A and HBS1L-MYB are the major modifiers of HbF in African Americans. Blood (2012) 1.12
Migration and fisheries of north east Atlantic mackerel (Scomber scombrus) in autumn and winter. PLoS One (2012) 1.12
Effects of JAK3 inhibition with CP-690,550 on immune cell populations and their functions in nonhuman primate recipients of kidney allografts. Transplantation (2005) 1.09
Angiogenic and inflammatory markers of cardiopulmonary changes in children and adolescents with sickle cell disease. PLoS One (2009) 1.07
Development of fully defined xeno-free culture system for the preparation and propagation of cell therapy-compliant human adipose stem cells. Stem Cell Res Ther (2013) 1.06
Markers of severe vaso-occlusive painful episode frequency in children and adolescents with sickle cell anemia. J Pediatr (2011) 1.05
Discovery of ABT-267, a pan-genotypic inhibitor of HCV NS5A. J Med Chem (2014) 1.05
Simplified technique for correction of anomalous origin of left coronary artery from the anterior aortic sinus. Ann Thorac Surg (2003) 1.04
Immunosuppression by the JAK3 inhibitor CP-690,550 delays rejection and significantly prolongs kidney allograft survival in nonhuman primates. Transplantation (2005) 1.04
Is medical therapy still the optimal treatment strategy for patients with acute type B aortic dissections? J Thorac Cardiovasc Surg (2002) 1.02
Retroaortic innominate vein with coarctation of the aorta: surgical repair and embryology review. Ann Thorac Surg (2003) 1.01
Tricyclic antidepressants for chronic vomiting in diabetic patients. Dig Dis Sci (2006) 1.01
Acute type A aortic dissection complicated by aortic regurgitation: composite valve graft versus separate valve graft versus conservative valve repair. J Thorac Cardiovasc Surg (2003) 0.98
Endoscopic management of pancreatic pseudocyst in children. Gastrointest Endosc (2002) 0.97
Using Facebook to deliver a social norm intervention to reduce problem drinking at university. Drug Alcohol Rev (2014) 0.97
The colon single-stripe sign and its relationship to ischemic colitis. Am J Gastroenterol (2003) 0.97
Radiolabeled absorption, distribution, metabolism, and excretion studies in drug development: why, when, and how? Chem Res Toxicol (2012) 0.96
Long-term results of heart transplantation in patients older than 60 years. J Thorac Cardiovasc Surg (2003) 0.96
Epidemiology of cardiac surgery-associated acute kidney injury in neonates: a retrospective study. Pediatr Nephrol (2013) 0.96
Combined use of the JAK3 inhibitor CP-690,550 with mycophenolate mofetil to prevent kidney allograft rejection in nonhuman primates. Transplantation (2005) 0.95
Fluorodeoxyglucose-positron emission tomography in the differential diagnosis of early-onset dementia: a prospective, community-based study. BMC Neurol (2009) 0.95
JAK3 inhibition, a viable new modality of immunosuppression for solid organ transplants. Trends Mol Med (2004) 0.95
Ageing, social capital and the Internet: findings from an exploratory study of Australian 'silver surfers'. Australas J Ageing (2008) 0.95
Outbreak of Mycobacterium bovis in a conditioned colony of rhesus (Macaca mulatta) and cynomolgus (Macaca fascicularis) macaques. Comp Med (2004) 0.94
Pneumatic paracorporeal ventricular assist device in infants and children: initial Stanford experience. J Heart Lung Transplant (2008) 0.93
Ecto-5'-nucleotidase (CD73) attenuates allograft airway rejection through adenosine 2A receptor stimulation. J Immunol (2010) 0.93
Zonisamide or levetiracetam for adults with cyclic vomiting syndrome: a case series. Clin Gastroenterol Hepatol (2006) 0.93
¹⁸F-Fluoromethylcholine (FCH) PET imaging in patients with castration-resistant prostate cancer: prospective comparison with standard imaging. Eur J Nucl Med Mol Imaging (2010) 0.90
Genetic determinants of haemolysis in sickle cell anaemia. Br J Haematol (2013) 0.89
Healthy connections: online social networks and their potential for peer support. Stud Health Technol Inform (2011) 0.89
UK hantavirus, renal failure, and pet rats. Lancet (2013) 0.89
Outcomes of pediatric patients bridged to heart transplantation from extracorporeal membrane oxygenation support. ASAIO J (2007) 0.89
Review of heart-lung transplantation at Stanford. Ann Thorac Surg (2010) 0.88
Fluoro-2-deoxy-D-glucose (FDG)-PET in APOEepsilon4 carriers in the Australian population. J Alzheimers Dis (2008) 0.88
Does profound hypothermic circulatory arrest improve survival in patients with acute type a aortic dissection? Circulation (2002) 0.88
Epidemiology of respiratory syncytial virus in children ≤2 years of age hospitalized with lower respiratory tract infections in the Russian Federation: a prospective, multicenter study. Clin Epidemiol (2010) 0.88
The pharmacokinetics, metabolism, and clearance mechanisms of tofacitinib, a janus kinase inhibitor, in humans. Drug Metab Dispos (2014) 0.87
Identification of the V genes encoding xenoantibodies in non-immunosuppressed rhesus monkeys. Immunology (2005) 0.87
P-selectin glycoprotein ligand-1 inhibition blocks increased leukocyte-endothelial interactions associated with sickle cell disease in mice. Blood (2012) 0.87
Compared with cyclosporine, ISATX247 significantly prolongs renal-allograft survival in a nonhuman primate model. Transplantation (2004) 0.87
Similarities in the immunoglobulin response and VH gene usage in rhesus monkeys and humans exposed to porcine hepatocytes. BMC Immunol (2006) 0.86
Abnormal pulmonary function and associated risk factors in children and adolescents with sickle cell anemia. J Pediatr Hematol Oncol (2014) 0.86
Association of G6PD with lower haemoglobin concentration but not increased haemolysis in patients with sickle cell anaemia. Br J Haematol (2010) 0.86
Human radiolabeled mass balance studies: objectives, utilities and limitations. Biopharm Drug Dispos (2009) 0.86
Concise review: guidance in developing commercializable autologous/patient-specific cell therapy manufacturing. Stem Cells Transl Med (2013) 0.85
Comparing online and offline self-disclosure: a systematic review. Cyberpsychol Behav Soc Netw (2011) 0.85
Single-ventricle anatomy predicts delayed microstructural brain development. Pediatr Res (2013) 0.85
Cytolytic T-cell response to the PASD1 cancer testis antigen in patients with diffuse large B-cell lymphoma. Br J Haematol (2009) 0.85
A xenogeneic-free bioreactor system for the clinical-scale expansion of human mesenchymal stem/stromal cells. Biotechnol Bioeng (2014) 0.85
Janus kinase 3 inhibition with CP-690,550 prevents allograft vasculopathy. Transpl Int (2006) 0.85
Pancreatitis following Olanzapine Therapy: A Report of Three Cases. Case Rep Gastroenterol (2007) 0.85
Clinical pharmacology of AMG 181, a gut-specific human anti-α4β7 monoclonal antibody, for treating inflammatory bowel diseases. Br J Clin Pharmacol (2014) 0.84
Immunosuppressive effects of surgery assessed by flow cytometry in nonhuman primates after nephrectomy. Transpl Int (2005) 0.84
Clinical correlates of acute pulmonary events in children and adolescents with sickle cell disease. Eur J Haematol (2013) 0.84
Perceptions and behaviour of access of the Internet: a study of women attending a breast screening service in Sydney, Australia. Int J Med Inform (2007) 0.84
High performance liquid chromatography/atmospheric pressure ionization/tandem mass spectrometry (HPLC/API/MS/MS) in drug metabolism and toxicology. Curr Drug Metab (2006) 0.84
Radiolabeled mass-balance excretion and metabolism studies in laboratory animals: a commentary on why they are still necessary. Xenobiotica (2012) 0.84
Plasma cefazolin levels during cardiovascular surgery: effects of cardiopulmonary bypass and profound hypothermic circulatory arrest. J Thorac Cardiovasc Surg (2006) 0.83
Clinical outcomes of splenectomy in children: report of the splenectomy in congenital hemolytic anemia registry. Am J Hematol (2014) 0.83
Could we still improve early and interim outcome after prosthetic systemic-pulmonary shunt? A risk factors analysis. Eur J Cardiothorac Surg (2008) 0.83
PGC-1 coactivator activity is required for murine erythropoiesis. Mol Cell Biol (2014) 0.82
Transient diabetes associated with withdrawal of lithium therapy. Diabetes Care (2006) 0.82
Intestinal strictures can impede wireless capsule enteroscopy. Gastrointest Endosc (2003) 0.82
Alternative technique for salvage of donor lungs with insufficient atrial cuffs. Ann Thorac Surg (2009) 0.81