Published in Genes Chromosomes Cancer on January 01, 2006
LINE-1 ORF1 protein localizes in stress granules with other RNA-binding proteins, including components of RNA interference RNA-induced silencing complex. Mol Cell Biol (2007) 1.79
Epigenomic consequences of immortalized plant cell suspension culture. PLoS Biol (2008) 1.68
Environmental exposures and gene regulation in disease etiology. Environ Health Perspect (2007) 1.44
Transcriptomic analysis of the exit from dormancy of Aspergillus fumigatus conidia. BMC Genomics (2008) 1.31
Human endogenous retrovirus (HERV-K) reverse transcriptase as a breast cancer prognostic marker. Neoplasia (2008) 1.24
Loss of epigenetic silencing in tumors preferentially affects primate-specific retroelements. Gene (2009) 1.19
Atypical relaxation of structural constraints in Hox gene clusters of the green anole lizard. Genome Res (2009) 1.06
Increased expression and copy number amplification of LINE-1 and SINE B1 retrotransposable elements in murine mammary carcinoma progression. Oncotarget (2013) 0.93
Retrotransposon long interspersed nucleotide element-1 (LINE-1) is activated during salamander limb regeneration. Dev Growth Differ (2012) 0.91
Inhibition of LINE-1 retrotransposon-encoded reverse transcriptase modulates the expression of cell differentiation genes in breast cancer cells. Breast Cancer Res Treat (2013) 0.89
Novel primate-specific genes, RMEL 1, 2 and 3, with highly restricted expression in melanoma, assessed by new data mining tool. PLoS One (2010) 0.81
Controlled and localized genetic manipulation in the brain. J Cell Mol Med (2006) 0.81
Restricting retrotransposons: a review. Mob DNA (2016) 0.79
Efavirenz Has the Highest Anti-Proliferative Effect of Non-Nucleoside Reverse Transcriptase Inhibitors against Pancreatic Cancer Cells. PLoS One (2015) 0.78
Activation of LINE-1 Retrotransposon Increases the Risk of Epithelial-Mesenchymal Transition and Metastasis in Epithelial Cancer. Curr Mol Med (2015) 0.77
LINE-1 family member GCRG123 gene is up-regulated in human gastric signet-ring cell carcinoma. World J Gastroenterol (2008) 0.76
Association between Long Interspersed Nuclear Element-1 Methylation and Relative Telomere Length in Wilms Tumor. Chin Med J (Engl) (2015) 0.75
Functional deficit of T regulatory cells in Fulani, an ethnic group with low susceptibility to Plasmodium falciparum malaria. Proc Natl Acad Sci U S A (2008) 1.86
Bcl-2 Phosphorylation by p38 MAPK: identification of target sites and biologic consequences. J Biol Chem (2006) 1.60
"Shock and kill" effects of class I-selective histone deacetylase inhibitors in combination with the glutathione synthesis inhibitor buthionine sulfoximine in cell line models for HIV-1 quiescence. Retrovirology (2009) 1.59
Part of Ran is associated with AKAP450 at the centrosome: involvement in microtubule-organizing activity. Mol Biol Cell (2003) 1.57
Macrophages and HIV infection: therapeutical approaches toward this strategic virus reservoir. Antiviral Res (2002) 1.57
A functional interplay between Aurora-A, Plk1 and TPX2 at spindle poles: Plk1 controls centrosomal localization of Aurora-A and TPX2 spindle association. Cell Cycle (2006) 1.52
In vitro evidence for a new therapeutic approach in renal cell carcinoma. Int Braz J Urol (2008) 1.44
Inhibition of influenza A virus replication by resveratrol. J Infect Dis (2005) 1.33
Inhibition of endogenous reverse transcriptase antagonizes human tumor growth. Oncogene (2005) 1.30
Expression of LINE-1 retroposons is essential for murine preimplantation development. Mol Reprod Dev (2006) 1.20
Mammalian RanBP1 regulates centrosome cohesion during mitosis. J Cell Sci (2003) 1.18
Thymosin alpha1 activates dendritic cell tryptophan catabolism and establishes a regulatory environment for balance of inflammation and tolerance. Blood (2006) 1.18
Mitotic functions of the Ran GTPase network: the importance of being in the right place at the right time. Cell Cycle (2004) 1.18
Localized RanGTP accumulation promotes microtubule nucleation at kinetochores in somatic mammalian cells. Mol Biol Cell (2008) 1.16
Response of a simian immunodeficiency virus (SIVmac251) to raltegravir: a basis for a new treatment for simian AIDS and an animal model for studying lentiviral persistence during antiretroviral therapy. Retrovirology (2010) 1.13
Therapeutic immunization with HIV-1 Tat reduces immune activation and loss of regulatory T-cells and improves immune function in subjects on HAART. PLoS One (2010) 1.13
Candidate HIV-1 Tat vaccine development: from basic science to clinical trials. AIDS (2006) 1.12
Importin beta is transported to spindle poles during mitosis and regulates Ran-dependent spindle assembly factors in mammalian cells. J Cell Sci (2004) 1.11
The Aurora-A/TPX2 complex: a novel oncogenic holoenzyme? Biochim Biophys Acta (2010) 1.10
Up-regulation of pro-inflammatory genes as adaptation to hypoxia in MCF-7 cells and in human mammary invasive carcinoma microenvironment. Cancer Sci (2010) 1.10
Control of Aurora-A stability through interaction with TPX2. J Cell Sci (2010) 1.09
Bcl-2 expression and p38MAPK activity in cells infected with influenza A virus: impact on virally induced apoptosis and viral replication. J Biol Chem (2009) 1.07
Influenza A virus replication is dependent on an antioxidant pathway that involves GSH and Bcl-2. FASEB J (2003) 1.07
Thymosin alpha 1 activates dendritic cells for antifungal Th1 resistance through toll-like receptor signaling. Blood (2004) 1.06
Gold drug auranofin restricts the viral reservoir in the monkey AIDS model and induces containment of viral load following ART suspension. AIDS (2011) 1.06
Exposure of normal and transformed cells to nevirapine, a reverse transcriptase inhibitor, reduces cell growth and promotes differentiation. Oncogene (2003) 1.05
E1A deregulates the centrosome cycle in a Ran GTPase-dependent manner. Cancer Res (2003) 1.04
Toward highly potent cancer agents by modulating the C-2 group of the arylthioindole class of tubulin polymerization inhibitors. J Med Chem (2012) 1.03
Infectious agents and neurodegeneration. Mol Neurobiol (2012) 1.03
Aurora-A inactivation causes mitotic spindle pole fragmentation by unbalancing microtubule-generated forces. Mol Cancer (2011) 1.03
RANBP1 localizes a subset of mitotic regulatory factors on spindle microtubules and regulates chromosome segregation in human cells. J Cell Sci (2007) 1.00
Multiplexed Cell Signaling Analysis of Metastatic and Nonmetastatic Colorectal Cancer Reveals COX2-EGFR Signaling Activation as a Potential Prognostic Pathway Biomarker. Clin Colorectal Cancer (2009) 1.00
Induction of autophagic cell death by a novel molecule is increased by hypoxia. Autophagy (2008) 0.99
GSH and analogs in antiviral therapy. Mol Aspects Med (2008) 0.98
LINE-1 retrotransposon copies are amplified during murine early embryo development. Mol Reprod Dev (2011) 0.97
Modulation of cell differentiation, proliferation, and tumor growth by dihydrobenzyloxopyrimidine non-nucleoside reverse transcriptase inhibitors. J Med Chem (2011) 0.96
Reverse transcriptase inhibitors down-regulate cell proliferation in vitro and in vivo and restore thyrotropin signaling and iodine uptake in human thyroid anaplastic carcinoma. J Clin Endocrinol Metab (2005) 0.96
Sex differences in the response to viral infections: TLR8 and TLR9 ligand stimulation induce higher IL10 production in males. PLoS One (2012) 0.96
p73 is regulated by phosphorylation at the G2/M transition. J Biol Chem (2003) 0.95
The preventive phase I trial with the HIV-1 Tat-based vaccine. Vaccine (2009) 0.95
The therapeutic phase I trial of the recombinant native HIV-1 Tat protein. AIDS (2008) 0.95
TCTP is a critical survival factor that protects cancer cells from oxidative stress-induced cell-death. Exp Cell Res (2011) 0.94
Antitumour effect of OM-174 and cyclophosphamide on murine B16 melanoma in different experimental conditions. Int Immunopharmacol (2005) 0.94
Increased expression and copy number amplification of LINE-1 and SINE B1 retrotransposable elements in murine mammary carcinoma progression. Oncotarget (2013) 0.93
Thymosin alpha1: an endogenous regulator of inflammation, immunity, and tolerance. Ann N Y Acad Sci (2007) 0.93
The GTPase Ran: regulation of cell life and potential roles in cell transformation. Front Biosci (2008) 0.92
Molecular basis for keratoconus: lack of TrkA expression and its transcriptional repression by Sp3. Proc Natl Acad Sci U S A (2005) 0.92
A role of p73 in mitotic exit. J Biol Chem (2005) 0.92
Histone deacetylase inhibitors may reduce pathogenicity and virulence in Candida albicans. FEMS Yeast Res (2007) 0.92
Sperm-mediated gene transfer: applications and implications. Bioessays (2005) 0.92
Drug-loaded red blood cell-mediated clearance of HIV-1 macrophage reservoir by selective inhibition of STAT1 expression. J Leukoc Biol (2003) 0.91
Redox regulation of the influenza hemagglutinin maturation process: a new cell-mediated strategy for anti-influenza therapy. Antioxid Redox Signal (2011) 0.91
HIV-1 tat promotes integrin-mediated HIV transmission to dendritic cells by binding Env spikes and competes neutralization by anti-HIV antibodies. PLoS One (2012) 0.91
APP processing induced by herpes simplex virus type 1 (HSV-1) yields several APP fragments in human and rat neuronal cells. PLoS One (2010) 0.90
Importin-β negatively regulates multiple aspects of mitosis including RANGAP1 recruitment to kinetochores. J Cell Biol (2012) 0.89
Rhinoviruses promote internalisation of Staphylococcus aureus into non-fully permissive cultured pneumocytes. Microbes Infect (2006) 0.89
A novel biomarker harvesting nanotechnology identifies Bak as a candidate melanoma biomarker in serum. Exp Dermatol (2011) 0.89
Investigational treatment suspension and enhanced cell-mediated immunity at rebound followed by drug-free remission of simian AIDS. Retrovirology (2013) 0.89
A tumor-promoting mechanism mediated by retrotransposon-encoded reverse transcriptase is active in human transformed cell lines. Oncotarget (2013) 0.89
HSV-1 promotes Ca2+ -mediated APP phosphorylation and Aβ accumulation in rat cortical neurons. Neurobiol Aging (2010) 0.89
Design and synthesis of 2-heterocyclyl-3-arylthio-1H-indoles as potent tubulin polymerization and cell growth inhibitors with improved metabolic stability. J Med Chem (2011) 0.89
Thymosin α1 as a stimulatory agent of innate cell-mediated immune response. Ann N Y Acad Sci (2012) 0.88
Influenza virus replication in lung epithelial cells depends on redox-sensitive pathways activated by NOX4-derived ROS. Cell Microbiol (2014) 0.87
New pyrrole derivatives with potent tubulin polymerization inhibiting activity as anticancer agents including hedgehog-dependent cancer. J Med Chem (2014) 0.87
Plasmodium falciparum soluble extracts potentiate the suppressive function of polyclonal T regulatory cells through activation of TGFβ-mediated signals. Cell Microbiol (2011) 0.87
Role of endogenous reverse transcriptase in murine early embryo development. Mol Reprod Dev (2003) 0.87
Neuroprotective effects of thymosin beta4 in experimental models of excitotoxicity. Ann N Y Acad Sci (2007) 0.86
Human endogenous retroviruses and ADHD. World J Biol Psychiatry (2013) 0.86
Nuclear reformation after mitosis requires downregulation of the Ran GTPase effector RanBP1 in mammalian cells. Chromosoma (2010) 0.86
Thymosin alpha1 activates the TLR9/MyD88/IRF7-dependent murine cytomegalovirus sensing for induction of anti-viral responses in vivo. Int Immunol (2007) 0.86
Pepstatin A alters host cell autophagic machinery and leads to a decrease in influenza A virus production. J Cell Physiol (2011) 0.86
Intracellular redox signaling as therapeutic target for novel antiviral strategy. Curr Pharm Des (2011) 0.85
Differentiation of human melanoma cells induced by cyanidin-3-O-beta-glucopyranoside. FASEB J (2004) 0.85
The Environmental Pollutant Cadmium Promotes Influenza Virus Replication in MDCK Cells by Altering Their Redox State. Int J Mol Sci (2013) 0.84
Stimulatory effect of Eucalyptus essential oil on innate cell-mediated immune response. BMC Immunol (2008) 0.84
Sperm endogenous reverse transcriptase as mediator of new genetic information. Biochem Biophys Res Commun (2003) 0.84
Nerve growth factor-dependent survival of CESS B cell line is mediated by increased expression and decreased degradation of MAPK phosphatase 1. J Biol Chem (2004) 0.84
Mouse early embryos obtained by natural breeding or in vitro fertilization display a differential sensitivity to extremely low-frequency electromagnetic fields. Mutat Res (2003) 0.83
Retrotransposons, reverse transcriptase and the genesis of new genetic information. Gene (2009) 0.83
Antitumor effects of the benzophenanthridine alkaloid sanguinarine in a rat syngeneic model of colorectal cancer. Anticancer Drugs (2012) 0.83
Viral hemagglutinin is involved in promoting the internalisation of Staphylococcus aureus into human pneumocytes during influenza A H1N1 virus infection. Int J Med Microbiol (2011) 0.83
Sublethal doses of β-amyloid peptide abrogate DNA-dependent protein kinase activity. J Biol Chem (2011) 0.83
Thymosin beta4 targeting impairs tumorigenic activity of colon cancer stem cells. FASEB J (2010) 0.83
Regulatory roles of LINE-1-encoded reverse transcriptase in cancer onset and progression. Oncotarget (2014) 0.82
Downregulation of thymosin beta4 in neural progenitor grafts promotes spinal cord regeneration. J Cell Sci (2009) 0.82
Modulation of the immune and inflammatory responses by Plasmodium falciparum schizont extracts: role of myeloid dendritic cells in effector and regulatory functions of CD4+ lymphocytes. Infect Immun (2013) 0.82
Generation of biologically active retro-genes upon interaction of mouse spermatozoa with exogenous DNA. Mol Reprod Dev (2006) 0.81
Transcription profile of human lymphocytes following in vitro treatment with thymosin alpha-1. Ann N Y Acad Sci (2010) 0.81
Retrotransposon-encoded reverse transcriptase in the genesis, progression and cellular plasticity of human cancer. Cancers (Basel) (2011) 0.81
Modulation of Th1/Th2 immune responses to HIV-1 Tat by new pro-GSH molecules. Vaccine (2011) 0.81
Influenza virus and redox mediated cell signaling: a complex network of virus/host interaction. New Microbiol (2007) 0.81
Segmental chromosome aberrations converge on overexpression of mitotic spindle regulatory genes in high-risk neuroblastoma. Genes Chromosomes Cancer (2012) 0.80
New CRIME plots. Ran and transport factors regulate mitosis. EMBO Rep (2005) 0.80
Ran control of mitosis in human cells: gradients and local signals. Biochem Soc Trans (2010) 0.80
New synthetic glutathione derivatives with increased antiviral activities. Antivir Chem Chemother (2004) 0.80
Therapeutic imprinting of the immune system: towards a remission of AIDS in primates? Retrovirology (2012) 0.79