Published in Am J Physiol Heart Circ Physiol on September 23, 2005
Endothelium-dependent vasodilatation and exercise hyperaemia in ageing humans: impact of acute ascorbic acid administration. J Physiol (2009) 2.00
Aging blunts the dynamics of vasodilation in isolated skeletal muscle resistance vessels. J Appl Physiol (1985) (2009) 1.77
NAD(P)H oxidase-derived reactive oxygen species contribute to age-related impairments of endothelium-dependent dilation in rat soleus feed arteries. J Appl Physiol (1985) (2011) 1.58
Mitochondrial dysfunction and sarcopenia of aging: from signaling pathways to clinical trials. Int J Biochem Cell Biol (2013) 1.38
Blunting of rapid onset vasodilatation and blood flow restriction in arterioles of exercising skeletal muscle with ageing in male mice. J Physiol (2010) 1.31
Exercise-induced brachial artery vasodilation: effects of antioxidants and exercise training in elderly men. Am J Physiol Heart Circ Physiol (2009) 1.24
Regulation of increased blood flow (hyperemia) to muscles during exercise: a hierarchy of competing physiological needs. Physiol Rev (2015) 1.19
Heterogeneity in conduit artery function in humans: impact of arterial size. Am J Physiol Heart Circ Physiol (2008) 1.14
Relationship of flow-mediated arterial dilation and exercise capacity in older patients with heart failure and preserved ejection fraction. J Gerontol A Biol Sci Med Sci (2012) 1.14
Ageing reduces the compensatory vasodilatation during hypoxic exercise: the role of nitric oxide. J Physiol (2011) 1.13
Attenuated exercise induced hyperaemia with age: mechanistic insight from passive limb movement. J Physiol (2010) 1.08
Multiparametric NMR-based assessment of skeletal muscle perfusion and metabolism during exercise in elderly persons: preliminary findings. J Gerontol A Biol Sci Med Sci (2009) 1.04
Contribution of nitric oxide in the contraction-induced rapid vasodilation in young and older adults. J Appl Physiol (1985) (2013) 0.99
Sedentary aging increases resting and exercise-induced intramuscular free radical formation. J Appl Physiol (1985) (2010) 0.99
Positron emission tomography detects greater blood flow and less blood flow heterogeneity in the exercising skeletal muscles of old compared with young men during fatiguing contractions. J Physiol (2013) 0.96
Evidence for sex differences in cardiovascular aging and adaptive responses to physical activity. Eur J Appl Physiol (2010) 0.95
Antioxidants and aging: NMR-based evidence of improved skeletal muscle perfusion and energetics. Am J Physiol Heart Circ Physiol (2009) 0.94
Influence of α-adrenergic vasoconstriction on the blunted skeletal muscle contraction-induced rapid vasodilation with aging. J Appl Physiol (1985) (2012) 0.94
The effects of resistance exercise training on macro- and micro-circulatory responses to feeding and skeletal muscle protein anabolism in older men. J Physiol (2015) 0.93
Role of {alpha}1-adrenergic vasoconstriction in the regulation of skeletal muscle blood flow with advancing age. Am J Physiol Heart Circ Physiol (2008) 0.93
The role of nitric oxide in passive leg movement-induced vasodilatation with age: insight from alterations in femoral perfusion pressure. J Physiol (2015) 0.93
Influence of ageing and physical activity on vascular morphology in rat skeletal muscle. J Physiol (2006) 0.93
Endothelin-A-mediated vasoconstriction during exercise with advancing age. J Gerontol A Biol Sci Med Sci (2014) 0.91
Perfusion pressure and movement-induced hyperemia: evidence of limited vascular function and vasodilatory reserve with age. Am J Physiol Heart Circ Physiol (2012) 0.90
Measuring muscle blood flow: a key link between systemic and regional metabolism. Curr Opin Clin Nutr Metab Care (2008) 0.89
Development of a new Sonovue™ contrast-enhanced ultrasound approach reveals temporal and age-related features of muscle microvascular responses to feeding. Physiol Rep (2013) 0.89
Oxidative damage in the gastrocnemius of patients with peripheral artery disease is myofiber type selective. Redox Biol (2014) 0.89
Rapid onset vasodilation with single muscle contractions in the leg: influence of age. Physiol Rep (2015) 0.89
Regulation of skeletal muscle blood flow during exercise in ageing humans. J Physiol (2015) 0.88
Aging alters reactivity of microvascular resistance networks in mouse gluteus maximus muscle. Am J Physiol Heart Circ Physiol (2014) 0.87
The role of muscle mass in exercise-induced hyperemia. J Appl Physiol (1985) (2014) 0.87
Ascorbate infusion increases skeletal muscle fatigue resistance in patients with chronic obstructive pulmonary disease. Am J Physiol Regul Integr Comp Physiol (2013) 0.87
Differences in exercise limb blood flow and muscle deoxygenation with age: contributions to O2 uptake kinetics. Eur J Appl Physiol (2010) 0.87
Reduced muscle oxidative capacity is independent of O2 availability in elderly people. Age (Dordr) (2012) 0.86
Effects of aging and exercise training on skeletal muscle blood flow and resistance artery morphology. J Appl Physiol (1985) (2012) 0.86
Differential effects of aging and exercise on intra-abdominal adipose arteriolar function and blood flow regulation. J Appl Physiol (1985) (2013) 0.86
Heterogeneous ageing of skeletal muscle microvascular function. J Physiol (2015) 0.84
Age and microvascular responses to knee extensor exercise in women. Eur J Appl Physiol (2008) 0.83
The validity of anthropometric leg muscle volume estimation across a wide spectrum: from able-bodied adults to individuals with a spinal cord injury. J Appl Physiol (1985) (2014) 0.82
Aging is associated with altered vasodilator kinetics in dynamically contracting muscle: role of nitric oxide. J Appl Physiol (1985) (2015) 0.82
Effect of muscle metaboreflex activation on spontaneous cardiac baroreflex sensitivity during exercise in humans. J Physiol (2011) 0.81
Contribution of nitric oxide to brachial artery vasodilation during progressive handgrip exercise in the elderly. Am J Physiol Regul Integr Comp Physiol (2013) 0.81
Oxidative stress and COPD: the effect of oral antioxidants on skeletal muscle fatigue. Med Sci Sports Exerc (2013) 0.81
Sex-specific effect of aging on submaximal leg exercise hemodynamics in middle-aged and older adults. Eur J Appl Physiol (2010) 0.80
Advanced age protects microvascular endothelium from aberrant Ca(2+) influx and cell death induced by hydrogen peroxide. J Physiol (2015) 0.80
Vessel-wall imaging and quantification of flow-mediated dilation using water-selective 3D SSFP-echo. J Cardiovasc Magn Reson (2013) 0.80
Sex and limb-specific ischemic reperfusion and vascular reactivity. Am J Physiol Heart Circ Physiol (2008) 0.80
Heterogeneous vascular responses to hypoxic forearm exercise in young and older adults. Eur J Appl Physiol (2011) 0.80
Sex differences with aging in nutritive skeletal muscle blood flow: impact of exercise training, nitric oxide, and α-adrenergic-mediated mechanisms. Am J Physiol Heart Circ Physiol (2014) 0.79
Aging alters muscle reflex control of autonomic cardiovascular responses to rhythmic contractions in humans. Am J Physiol Heart Circ Physiol (2015) 0.79
Evidence of Preserved Oxidative Capacity and Oxygen Delivery in the Plantar Flexor Muscles With Age. J Gerontol A Biol Sci Med Sci (2014) 0.78
Muscle fibre capillarization is a critical factor in muscle fibre hypertrophy during resistance exercise training in older men. J Cachexia Sarcopenia Muscle (2016) 0.78
Insights into central and peripheral factors affecting the "oxidative performance" of skeletal muscle in aging. Eur J Appl Physiol (2006) 0.76
Acute dietary nitrate supplementation enhances compensatory vasodilation during hypoxic exercise in older adults. J Appl Physiol (1985) (2014) 0.76
Age-related differences in skeletal muscle microvascular response to exercise as detected by contrast-enhanced ultrasound (CEUS). PLoS One (2017) 0.75
The Effect of Physical Activity on Passive Leg Movement-Induced Vasodilation with Age. Med Sci Sports Exerc (2016) 0.75
Impact of age on exercise-induced ATP supply during supramaximal plantar flexion in humans. Am J Physiol Regul Integr Comp Physiol (2015) 0.75
Mechanical compression during repeated sustained isometric muscle contractions and hyperemic recovery in healthy young males. J Physiol Anthropol (2015) 0.75
Evidence of a metabolic reserve in the skeletal muscle of elderly people. Aging (Albany NY) (2016) 0.75
Physiological alterations after a marathon in the first 90-year-old male finisher: case study. Springerplus (2014) 0.75
Altered Blood Flow Response to Small Muscle Mass Exercise in Cancer Survivors Treated With Adjuvant Therapy. J Am Heart Assoc (2017) 0.75
Folic Acid Ingestion Improves Skeletal Muscle Blood Flow during Graded Handgrip and Plantar Flexion Exercise in Aged Humans. Am J Physiol Heart Circ Physiol (2017) 0.75
Ultrasound assessment of flow-mediated dilation. Hypertension (2010) 2.48
Maximal strength training and increased work efficiency: contribution from the trained muscle bed. J Appl Physiol (1985) (2012) 2.18
Endothelial dysfunction induced by post-prandial lipemia: complete protection afforded by high-intensity aerobic interval exercise. J Am Coll Cardiol (2009) 1.83
Acute reversal of endothelial dysfunction in the elderly after antioxidant consumption. Hypertension (2012) 1.79
The prognostic value of early repolarization with ST-segment elevation in African Americans. Heart Rhythm (2011) 1.75
MRS Evidence of Adequate O2 Supply in Human Skeletal Muscle at the Onset of Exercise. Med Sci Sports Exerc (2015) 1.60
Point: skeletal muscle mechanical efficiency does increase with age. J Appl Physiol (1985) (2012) 1.56
Vascular dysfunction and chronic obstructive pulmonary disease: the role of redox balance. Hypertension (2013) 1.54
Peripheral fatigue limits endurance exercise via a sensory feedback-mediated reduction in spinal motoneuronal output. J Appl Physiol (1985) (2013) 1.54
On the contribution of group III and IV muscle afferents to the circulatory response to rhythmic exercise in humans. J Physiol (2011) 1.39
Limited maximal exercise capacity in patients with chronic heart failure: partitioning the contributors. J Am Coll Cardiol (2010) 1.38
Human skeletal muscle intracellular oxygenation: the impact of ambient oxygen availability. J Physiol (2006) 1.27
Exercise-induced brachial artery vasodilation: effects of antioxidants and exercise training in elderly men. Am J Physiol Heart Circ Physiol (2009) 1.24
Exercise and nitric oxide prevent bubble formation: a novel approach to the prevention of decompression sickness? J Physiol (2004) 1.22
Exercise-induced brachial artery vasodilation: role of free radicals. Am J Physiol Heart Circ Physiol (2006) 1.21
Oral antioxidants and cardiovascular health in the exercise-trained and untrained elderly: a radically different outcome. Clin Sci (Lond) (2009) 1.19
Limb-specific differences in flow-mediated dilation: the role of shear rate. J Appl Physiol (1985) (2007) 1.18
Aging affects vascular structure and function in a limb-specific manner. J Appl Physiol (1985) (2008) 1.16
Onset exercise hyperaemia in humans: partitioning the contributors. J Physiol (2005) 1.15
Skeletal muscle oxidative metabolism in sedentary humans: 31P-MRS assessment of O2 supply and demand limitations. J Appl Physiol (1985) (2004) 1.15
The role of α-adrenergic receptors in mediating beat-by-beat sympathetic vascular transduction in the forearm of resting man. J Physiol (2013) 1.14
Regulation of free radical outflow from an isolated muscle bed in exercising humans. Am J Physiol Heart Circ Physiol (2004) 1.14
Evidence of preserved endothelial function and vascular plasticity with age. Am J Physiol Heart Circ Physiol (2005) 1.12
NOS inhibition increases bubble formation and reduces survival in sedentary but not exercised rats. J Physiol (2003) 1.10
Progressive handgrip exercise: evidence of nitric oxide-dependent vasodilation and blood flow regulation in humans. Am J Physiol Heart Circ Physiol (2011) 1.10
Effect of acetazolamide on pulmonary and muscle gas exchange during normoxic and hypoxic exercise. J Physiol (2007) 1.09
EPR spectroscopic detection of free radical outflow from an isolated muscle bed in exercising humans. J Appl Physiol (1985) (2003) 1.09
The effect of oral antioxidants on brachial artery flow-mediated dilation following 5 and 10 min of ischemia. Eur J Appl Physiol (2009) 1.09
Attenuated exercise induced hyperaemia with age: mechanistic insight from passive limb movement. J Physiol (2010) 1.08
Electron paramagnetic spectroscopic evidence of exercise-induced free radical accumulation in human skeletal muscle. Free Radic Res (2007) 1.08
Carotid baroreflex responsiveness to head-up tilt-induced central hypovolaemia: effect of aerobic fitness. J Physiol (2003) 1.07
Heterogeneous limb vascular responsiveness to shear stimuli during dynamic exercise in humans. J Appl Physiol (1985) (2005) 1.06
Nitric oxide and passive limb movement: a new approach to assess vascular function. J Physiol (2012) 1.05
Multiparametric NMR-based assessment of skeletal muscle perfusion and metabolism during exercise in elderly persons: preliminary findings. J Gerontol A Biol Sci Med Sci (2009) 1.04
Central and peripheral contributors to skeletal muscle hyperemia: response to passive limb movement. J Appl Physiol (1985) (2009) 1.04
Maximal strength training of the legs in COPD: a therapy for mechanical inefficiency. Med Sci Sports Exerc (2007) 1.00
Carotid baroreflex control of leg vascular conductance at rest and during exercise. J Appl Physiol (1985) (2002) 0.99
Acute sympathetic vasoconstriction at rest and during dynamic exercise in cyclists and sedentary humans. J Appl Physiol (1985) (2006) 0.99
Limb movement-induced hyperemia has a central hemodynamic component: evidence from a neural blockade study. Am J Physiol Heart Circ Physiol (2010) 0.99
Sedentary aging increases resting and exercise-induced intramuscular free radical formation. J Appl Physiol (1985) (2010) 0.99
In vivo evidence of an age-related increase in ATP cost of contraction in the plantar flexor muscles. Clin Sci (Lond) (2014) 0.99
Endothelin-1-mediated vasoconstriction at rest and during dynamic exercise in healthy humans. Am J Physiol Heart Circ Physiol (2007) 0.98
Isolated quadriceps training increases maximal exercise capacity in chronic heart failure: the role of skeletal muscle convective and diffusive oxygen transport. J Am Coll Cardiol (2011) 0.97
Genome based cell population heterogeneity promotes tumorigenicity: the evolutionary mechanism of cancer. J Cell Physiol (2009) 0.97
Oxygen availability and PCr recovery rate in untrained human calf muscle: evidence of metabolic limitation in normoxia. Am J Physiol Regul Integr Comp Physiol (2007) 0.97
α1-Adrenergic responsiveness in human skeletal muscle feed arteries: the impact of reducing extracellular pH. Exp Physiol (2012) 0.95
Impact of body position on central and peripheral hemodynamic contributions to movement-induced hyperemia: implications for rehabilitative medicine. Am J Physiol Heart Circ Physiol (2011) 0.95
Does brachial artery flow-mediated vasodilation provide a bioassay for NO? Hypertension (2013) 0.94
Antioxidants and aging: NMR-based evidence of improved skeletal muscle perfusion and energetics. Am J Physiol Heart Circ Physiol (2009) 0.94
Exercise-induced inhibition of angiotensin II vasoconstriction in human thigh muscle. J Physiol (2006) 0.94
Role of {alpha}1-adrenergic vasoconstriction in the regulation of skeletal muscle blood flow with advancing age. Am J Physiol Heart Circ Physiol (2008) 0.93
Understanding exercise-induced hyperemia: central and peripheral hemodynamic responses to passive limb movement in heart transplant recipients. Am J Physiol Heart Circ Physiol (2010) 0.93
The role of oxygen in determining phosphocreatine onset kinetics in exercising humans. J Physiol (2004) 0.92
Taming the "sleeping giant": the role of endothelin-1 in the regulation of skeletal muscle blood flow and arterial blood pressure during exercise. Am J Physiol Heart Circ Physiol (2012) 0.92
Angiotensin II in the elderly: impact of angiotensin II type 1 receptor sensitivity on peripheral hemodynamics. Hypertension (2008) 0.92
Vascular function and the role of oxidative stress in heart failure, heart transplant, and beyond. Hypertension (2012) 0.91
Human muscle length-dependent changes in blood flow. J Appl Physiol (1985) (2011) 0.91
Human skeletal muscle feed arteries studied in vitro: the effect of temperature on α(1)-adrenergic responsiveness. Exp Physiol (2011) 0.90
Angiotensin II potentiates α-adrenergic vasoconstriction in the elderly. Clin Sci (Lond) (2013) 0.90
Age-related telomere uncapping is associated with cellular senescence and inflammation independent of telomere shortening in human arteries. Am J Physiol Heart Circ Physiol (2013) 0.90
Perfusion pressure and movement-induced hyperemia: evidence of limited vascular function and vasodilatory reserve with age. Am J Physiol Heart Circ Physiol (2012) 0.90
Evidence against redox regulation of energy homoeostasis in humans at high altitude. Clin Sci (Lond) (2004) 0.89
Exercise-training-induced changes in metabolic capacity with age: the role of central cardiovascular plasticity. Age (Dordr) (2013) 0.89
Aging, exercise, and limb vascular heterogeneity in humans. Med Sci Sports Exerc (2006) 0.88
The role of muscle mass in exercise-induced hyperemia. J Appl Physiol (1985) (2014) 0.87
Limitations to vasodilatory capacity and .VO2 max in trained human skeletal muscle. Am J Physiol Heart Circ Physiol (2007) 0.87
Ascorbate infusion increases skeletal muscle fatigue resistance in patients with chronic obstructive pulmonary disease. Am J Physiol Regul Integr Comp Physiol (2013) 0.87
Epr spectroscopic evidence of free radical outflow from an isolated muscle bed in exercising humans: functional significance of decreasing intracellular PO2 vs. increasing O2 flux. Adv Exp Med Biol (2003) 0.86
Heat and α1-adrenergic responsiveness in human skeletal muscle feed arteries: the role of nitric oxide. J Appl Physiol (1985) (2012) 0.86
Reduced muscle oxidative capacity is independent of O2 availability in elderly people. Age (Dordr) (2012) 0.86
The paradox of oxidative stress and exercise with advancing age. Exerc Sport Sci Rev (2011) 0.85
Metabolic and vascular limb differences affected by exercise, gender, age, and disease. Med Sci Sports Exerc (2006) 0.85