Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
1
|
Neurobiology, pharmacology, and medicinal chemistry of neuropeptide S and its receptor.
|
Med Res Rev
|
2010
|
1.09
|
2
|
Urantide mimics urotensin-II induced calcium release in cells expressing recombinant UT receptors.
|
Eur J Pharmacol
|
2004
|
1.04
|
3
|
In vitro and in vivo pharmacological characterization of the novel NK₁ receptor selective antagonist Netupitant.
|
Peptides
|
2012
|
0.97
|
4
|
Further studies on the pharmacological profile of the neuropeptide S receptor antagonist SHA 68.
|
Peptides
|
2010
|
0.97
|
5
|
Antidepressant- and anxiolytic-like effects of nociceptin/orphanin FQ receptor ligands.
|
Naunyn Schmiedebergs Arch Pharmacol
|
2006
|
0.93
|
6
|
Nociceptin/orphanin FQ receptor antagonists as innovative antidepressant drugs.
|
Pharmacol Ther
|
2013
|
0.92
|
7
|
Pharmacological characterization of the nociceptin/orphanin FQ receptor non peptide antagonist Compound 24.
|
Eur J Pharmacol
|
2009
|
0.92
|
8
|
Central injections of nocistatin or its C-terminal hexapeptide exert anxiogenic-like effect on behaviour of mice in the plus-maze test.
|
Br J Pharmacol
|
2002
|
0.91
|
9
|
Chimeric G proteins in fluorimetric calcium assays: experience with opioid receptors.
|
Methods Mol Biol
|
2013
|
0.91
|
10
|
[Arg(14),Lys(15)]nociceptin, a highly potent agonist of the nociceptin/orphanin FQ receptor: in vitro and in vivo studies.
|
J Pharmacol Exp Ther
|
2002
|
0.89
|
11
|
Structure-activity study at positions 3 and 4 of human neuropeptide S.
|
Bioorg Med Chem
|
2008
|
0.88
|
12
|
Altered anxiety-related behavior in nociceptin/orphanin FQ receptor gene knockout mice.
|
Peptides
|
2007
|
0.87
|
13
|
The peptidic urotensin-II receptor ligand GSK248451 possesses less intrinsic activity than the low-efficacy partial agonists SB-710411 and urantide in native mammalian tissues and recombinant cell systems.
|
Br J Pharmacol
|
2006
|
0.87
|
14
|
Nociceptin receptor antagonists display antidepressant-like properties in the mouse forced swimming test.
|
Naunyn Schmiedebergs Arch Pharmacol
|
2001
|
0.87
|
15
|
Identification of an achiral analogue of J-113397 as potent nociceptin/orphanin FQ receptor antagonist.
|
Bioorg Med Chem
|
2005
|
0.86
|
16
|
Structure-activity studies on the nociceptin/orphanin FQ receptor antagonist 1-benzyl-N-{3-[spiroisobenzofuran-1(3H),4'-piperidin-1-yl]propyl} pyrrolidine-2-carboxamide.
|
Bioorg Med Chem
|
2009
|
0.85
|
17
|
Endogenous nociceptin/orphanin FQ signalling produces opposite spinal antinociceptive and supraspinal pronociceptive effects in the mouse formalin test: pharmacological and genetic evidences.
|
Pain
|
2006
|
0.84
|
18
|
Blockade of adenosine A2A receptor counteracts neuropeptide-S-induced hyperlocomotion in mice.
|
Naunyn Schmiedebergs Arch Pharmacol
|
2009
|
0.84
|
19
|
Dmt-Tic-NH-CH2-Bid (UFP-502), a potent DOP receptor agonist: in vitro and in vivo studies.
|
Peptides
|
2006
|
0.84
|
20
|
[(pF)Phe4,Arg14,Lys15]N/OFQ-NH2 (UFP-102), a highly potent and selective agonist of the nociceptin/orphanin FQ receptor.
|
J Pharmacol Exp Ther
|
2004
|
0.83
|
21
|
Functional selectivity of nociceptin/orphanin FQ peptide receptor partial agonists on cardiovascular and renal function.
|
J Pharmacol Exp Ther
|
2005
|
0.83
|
22
|
Pharmacological characterization of the novel nociceptin/orphanin FQ receptor ligand, ZP120: in vitro and in vivo studies in mice.
|
Br J Pharmacol
|
2002
|
0.82
|
23
|
Urotensin II stimulates plasma extravasation in mice via UT receptor activation.
|
Naunyn Schmiedebergs Arch Pharmacol
|
2004
|
0.82
|
24
|
Pharmacological profiles of presynaptic nociceptin/orphanin FQ receptors modulating 5-hydroxytryptamine and noradrenaline release in the rat neocortex.
|
Br J Pharmacol
|
2003
|
0.81
|
25
|
Effects of nociceptin/orphanin FQ receptor ligands on blood pressure, heart rate, and plasma catecholamine concentrations in guinea pigs.
|
Naunyn Schmiedebergs Arch Pharmacol
|
2003
|
0.81
|
26
|
Nociceptin/orphanin FQ receptor knockout rats: in vitro and in vivo studies.
|
Neuropharmacology
|
2010
|
0.80
|
27
|
Role of the ecto-nucleotidases in the cooperative effect of adenosine and neuropeptide-S on locomotor activity in mice.
|
Pharmacol Biochem Behav
|
2011
|
0.79
|
28
|
Pharmacological characterisation of [(pX)Phe4]nociceptin(1-13)amide analogues. 1. In vitro studies.
|
Naunyn Schmiedebergs Arch Pharmacol
|
2002
|
0.78
|
29
|
Urotensin II evokes neurotransmitter release from rat cerebrocortical slices.
|
Neurosci Lett
|
2008
|
0.78
|
30
|
Effects of chronic nociceptin/orphanin FQ exposure on cAMP accumulation and receptor density in Chinese hamster ovary cells expressing human nociceptin/orphanin FQ receptors.
|
Eur J Pharmacol
|
2002
|
0.77
|
31
|
Nociceptin/Orphanin FQ(1-13)NH2 analogues modified in the Phe1-Gly2 peptide bond.
|
Bioorg Med Chem Lett
|
2003
|
0.76
|
32
|
Pharmacological characterisation of [(pX)Phe4]nociceptin(1-13)NH2 analogues. 2. In vivo studies.
|
Naunyn Schmiedebergs Arch Pharmacol
|
2002
|
0.76
|
33
|
Quantitative study of [(pF)Phe4,Arg14,Lys15]nociceptin/orphanin FQ-NH2 (UFP-102) at NOP receptors in rat periaqueductal gray slices.
|
Eur J Pharmacol
|
2007
|
0.75
|
34
|
Comparative biochemical and pharmacological characterization of a novel, NOP receptor selective hexapeptide, Ac-RYYRIR-ol.
|
Brain Res Bull
|
2009
|
0.75
|
35
|
Effects of neuropeptide S on seizures and oxidative damage induced by pentylenetetrazole in mice.
|
Pharmacol Biochem Behav
|
2012
|
0.75
|
36
|
[Nphe1,Arg14,Lys15]N/OFQ-NH2 is a competitive antagonist of NOP receptors in the periaqueductal gray.
|
Eur J Pharmacol
|
2005
|
0.75
|
37
|
Nociceptin/orphanin FQ induces simultaneously anxiolytic and amnesic effects in the mouse elevated T-maze task.
|
Naunyn Schmiedebergs Arch Pharmacol
|
2014
|
0.75
|
38
|
Structure-activity relationship study on Tyr9 of urotensin-II(4-11): identification of a partial agonist of the UT receptor.
|
Peptides
|
2009
|
0.75
|
39
|
Ring size in cyclic endomorphin-2 analogs modulates receptor binding affinity and selectivity.
|
Org Biomol Chem
|
2015
|
0.75
|
40
|
Structure-activity relationship study of position 4 in the urotensin-II receptor ligand U-II(4-11).
|
Peptides
|
2007
|
0.75
|