| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Activation of the nuclear factor kappaB pathway by astrocyte elevated gene-1: implications for tumor progression and metastasis.
|
Cancer Res
|
2006
|
2.60
|
|
2
|
Stress and radiation-induced activation of multiple intracellular signaling pathways.
|
Radiat Res
|
2003
|
2.49
|
|
3
|
Improved ATM kinase inhibitor KU-60019 radiosensitizes glioma cells, compromises insulin, AKT and ERK prosurvival signaling, and inhibits migration and invasion.
|
Mol Cancer Ther
|
2009
|
2.08
|
|
4
|
mda-7 (IL-24) Mediates selective apoptosis in human melanoma cells by inducing the coordinated overexpression of the GADD family of genes by means of p38 MAPK.
|
Proc Natl Acad Sci U S A
|
2002
|
1.91
|
|
5
|
Extracellular signal-related kinase positively regulates ataxia telangiectasia mutated, homologous recombination repair, and the DNA damage response.
|
Cancer Res
|
2007
|
1.84
|
|
6
|
Expression analysis and genomic characterization of human melanoma differentiation associated gene-5, mda-5: a novel type I interferon-responsive apoptosis-inducing gene.
|
Oncogene
|
2004
|
1.83
|
|
7
|
Bile acid regulation of C/EBPbeta, CREB, and c-Jun function, via the extracellular signal-regulated kinase and c-Jun NH2-terminal kinase pathways, modulates the apoptotic response of hepatocytes.
|
Mol Cell Biol
|
2003
|
1.72
|
|
8
|
BLM helicase-dependent transport of p53 to sites of stalled DNA replication forks modulates homologous recombination.
|
EMBO J
|
2003
|
1.71
|
|
9
|
Radiosensitization of MDA-MB-231 breast tumor cells by adenovirus-mediated overexpression of a fragment of the XRCC4 protein.
|
Mol Cancer Ther
|
2005
|
1.59
|
|
10
|
BiP/GRP78 is an intracellular target for MDA-7/IL-24 induction of cancer-specific apoptosis.
|
Cancer Res
|
2006
|
1.58
|
|
11
|
Deficiency in 3'-phosphoglycolate processing in human cells with a hereditary mutation in tyrosyl-DNA phosphodiesterase (TDP1).
|
Nucleic Acids Res
|
2005
|
1.56
|
|
12
|
Pro-survival AKT and ERK signaling from EGFR and mutant EGFRvIII enhances DNA double-strand break repair in human glioma cells.
|
Cancer Biol Ther
|
2009
|
1.55
|
|
13
|
Double strand break repair by homologous recombination is regulated by cell cycle-independent signaling via ATM in human glioma cells.
|
J Biol Chem
|
2004
|
1.49
|
|
14
|
Melanoma differentiation associated gene-7, mda-7/IL-24, selectively induces growth suppression, apoptosis and radiosensitization in malignant gliomas in a p53-independent manner.
|
Oncogene
|
2003
|
1.41
|
|
15
|
Dynamic dependence on ATR and ATM for double-strand break repair in human embryonic stem cells and neural descendants.
|
PLoS One
|
2010
|
1.39
|
|
16
|
Coordinate 5' and 3' endonucleolytic trimming of terminally blocked blunt DNA double-strand break ends by Artemis nuclease and DNA-dependent protein kinase.
|
Nucleic Acids Res
|
2008
|
1.36
|
|
17
|
mda-9/Syntenin: a positive regulator of melanoma metastasis.
|
Cancer Res
|
2005
|
1.35
|
|
18
|
Radiation-induced activation of a common variant of EGFR confers enhanced radioresistance.
|
Radiother Oncol
|
2004
|
1.30
|
|
19
|
Ionizing radiation activates Erb-B receptor dependent Akt and p70 S6 kinase signaling in carcinoma cells.
|
Oncogene
|
2002
|
1.29
|
|
20
|
Involvement of Crm1 in hepatitis B virus X protein-induced aberrant centriole replication and abnormal mitotic spindles.
|
Mol Cell Biol
|
2003
|
1.24
|
|
21
|
Cloning and characterization of SARI (suppressor of AP-1, regulated by IFN).
|
Proc Natl Acad Sci U S A
|
2008
|
1.22
|
|
22
|
Identification and cloning of human polynucleotide phosphorylase, hPNPase old-35, in the context of terminal differentiation and cellular senescence.
|
Proc Natl Acad Sci U S A
|
2002
|
1.20
|
|
23
|
Requirement of Tyr-992 and Tyr-1173 in phosphorylation of the epidermal growth factor receptor by ionizing radiation and modulation by SHP2.
|
J Biol Chem
|
2005
|
1.18
|
|
24
|
ATM-dependent ERK signaling via AKT in response to DNA double-strand breaks.
|
Cell Cycle
|
2011
|
1.18
|
|
25
|
Targeting gene expression selectively in cancer cells by using the progression-elevated gene-3 promoter.
|
Proc Natl Acad Sci U S A
|
2005
|
1.17
|
|
26
|
Melanoma differentiation associated gene-7/interleukin-24 promotes tumor cell-specific apoptosis through both secretory and nonsecretory pathways.
|
Cancer Res
|
2004
|
1.17
|
|
27
|
ATM kinase inhibition preferentially sensitizes p53-mutant glioma to ionizing radiation.
|
Clin Cancer Res
|
2013
|
1.15
|
|
28
|
Tyrosyl-DNA phosphodiesterase and the repair of 3'-phosphoglycolate-terminated DNA double-strand breaks.
|
DNA Repair (Amst)
|
2009
|
1.13
|
|
29
|
Mitochondrial localized Stat3 promotes breast cancer growth via phosphorylation of serine 727.
|
J Biol Chem
|
2013
|
1.12
|
|
30
|
Molecular target-based therapy of pancreatic cancer.
|
Cancer Res
|
2006
|
1.12
|
|
31
|
EGFRvIII-mediated radioresistance through a strong cytoprotective response.
|
Oncogene
|
2003
|
1.11
|
|
32
|
ATM-independent, high-fidelity nonhomologous end joining predominates in human embryonic stem cells.
|
Aging (Albany NY)
|
2010
|
1.09
|
|
33
|
Defining the domains of human polynucleotide phosphorylase (hPNPaseOLD-35) mediating cellular senescence.
|
Mol Cell Biol
|
2005
|
1.09
|
|
34
|
Compensatory ErbB3/c-Src signaling enhances carcinoma cell survival to ionizing radiation.
|
Breast Cancer Res Treat
|
2006
|
1.08
|
|
35
|
Epidermal growth factor receptor dependence of radiation-induced transcription factor activation in human breast carcinoma cells.
|
Mol Biol Cell
|
2002
|
1.06
|
|
36
|
Down-regulation of Myc as a potential target for growth arrest induced by human polynucleotide phosphorylase (hPNPaseold-35) in human melanoma cells.
|
J Biol Chem
|
2003
|
1.05
|
|
37
|
MDA-7 (interleukin-24) inhibits the proliferation of renal carcinoma cells and interacts with free radicals to promote cell death and loss of reproductive capacity.
|
Mol Cancer Ther
|
2003
|
1.04
|
|
38
|
Phosphorylation in the serine/threonine 2609-2647 cluster promotes but is not essential for DNA-dependent protein kinase-mediated nonhomologous end joining in human whole-cell extracts.
|
Nucleic Acids Res
|
2007
|
1.04
|
|
39
|
Dynamic inhibition of ATM kinase provides a strategy for glioblastoma multiforme radiosensitization and growth control.
|
Cell Cycle
|
2012
|
1.04
|
|
40
|
The autophagy-senescence connection in chemotherapy: must tumor cells (self) eat before they sleep?
|
J Pharmacol Exp Ther
|
2012
|
1.03
|
|
41
|
Targeted virus replication plus immunotherapy eradicates primary and distant pancreatic tumors in nude mice.
|
Cancer Res
|
2005
|
1.02
|
|
42
|
SAGE transcript profiles of normal primary human hepatocytes expressing oncogenic hepatitis B virus X protein.
|
FASEB J
|
2002
|
1.01
|
|
43
|
N-glycosylation of MDA-7/IL-24 is dispensable for tumor cell-specific apoptosis and "bystander" antitumor activity.
|
Cancer Res
|
2006
|
1.01
|
|
44
|
Inhibition of the type III epidermal growth factor receptor variant mutant receptor by dominant-negative EGFR-CD533 enhances malignant glioma cell radiosensitivity.
|
Clin Cancer Res
|
2004
|
1.01
|
|
45
|
UVB-mediated activation of p38 mitogen-activated protein kinase enhances resistance of normal human keratinocytes to apoptosis by stabilizing cytoplasmic p53.
|
Biochem J
|
2002
|
1.00
|
|
46
|
Requirement for XLF/Cernunnos in alignment-based gap filling by DNA polymerases lambda and mu for nonhomologous end joining in human whole-cell extracts.
|
Nucleic Acids Res
|
2009
|
0.99
|
|
47
|
Mutations in the BRCT binding site of BRCA1 result in hyper-recombination.
|
Aging (Albany NY)
|
2011
|
0.99
|
|
48
|
Nuclear factor I isoforms regulate gene expression during the differentiation of human neural progenitors to astrocytes.
|
Stem Cells
|
2009
|
0.99
|
|
49
|
In vitro complementation of Tdp1 deficiency indicates a stabilized enzyme-DNA adduct from tyrosyl but not glycolate lesions as a consequence of the SCAN1 mutation.
|
DNA Repair (Amst)
|
2009
|
0.95
|
|
50
|
Nanomaterial-mediated CNS delivery of diagnostic and therapeutic agents.
|
Adv Drug Deliv Rev
|
2011
|
0.92
|
|
51
|
Adenovirus expressing p53.
|
Methods Mol Biol
|
2003
|
0.90
|
|
52
|
The Influence of Hypoxia and pH on Bioluminescence Imaging of Luciferase-Transfected Tumor Cells and Xenografts.
|
Int J Mol Imaging
|
2013
|
0.90
|
|
53
|
DNA double-strand break - induced pro-survival signaling.
|
Radiother Oncol
|
2011
|
0.90
|
|
54
|
Effect of hepatitis C virus core protein on the molecular profiling of human B lymphocytes.
|
Mol Med
|
2006
|
0.90
|
|
55
|
ErbB receptor tyrosine kinase network inhibition radiosensitizes carcinoma cells.
|
Int J Radiat Oncol Biol Phys
|
2006
|
0.87
|
|
56
|
Dominant-negative cAMP-responsive element-binding protein inhibits proliferating cell nuclear antigen and DNA repair, leading to increased cellular radiosensitivity.
|
J Biol Chem
|
2003
|
0.86
|
|
57
|
Ligand modulation of a dinuclear platinum compound leads to mechanistic differences in cell cycle progression and arrest.
|
Biochem Pharmacol
|
2013
|
0.86
|
|
58
|
BRCA1-directed, enhanced and aberrant homologous recombination: mechanism and potential treatment strategies.
|
Cell Cycle
|
2012
|
0.85
|
|
59
|
Novel mode for neutrophil protease cathepsin G-mediated signaling: membrane shedding of epidermal growth factor is required for cardiomyocyte anoikis.
|
Circ Res
|
2007
|
0.85
|
|
60
|
Progression elevated gene-3 promoter (PEG-Prom) confers cancer cell selectivity to human polynucleotide phosphorylase (hPNPase(old-35))-mediated growth suppression.
|
J Cell Physiol
|
2008
|
0.83
|
|
61
|
Radiosensitization of human glioma cells in vitro and in vivo with acyclovir and mutant HSV-TK75 expressed from adenovirus.
|
Int J Radiat Oncol Biol Phys
|
2002
|
0.81
|
|
62
|
MRE11 and ATM AKTivate pro-survival signaling.
|
Cell Cycle
|
2011
|
0.80
|
|
63
|
Curcumin inhibits ultraviolet light induced human immunodeficiency virus gene expression.
|
Mol Cell Biochem
|
2003
|
0.80
|
|
64
|
Activation of the stress-activated JNK and p38 MAP kinases in human cells by Photofrin-mediated photodynamic therapy.
|
J Photochem Photobiol B
|
2003
|
0.80
|
|
65
|
Synthesis of water-soluble camptothecin-polyoxetane conjugates via click chemistry.
|
Mol Pharm
|
2012
|
0.79
|
|
66
|
Triggering of apoptosis is not sufficient to induce human immunodeficiency virus gene expression.
|
IUBMB Life
|
2003
|
0.79
|
|
67
|
Peptide library approach to uncover phosphomimetic inhibitors of the BRCA1 C-terminal domain.
|
ACS Chem Biol
|
2015
|
0.78
|
|
68
|
Human chorionic gonadotropin modulates prostate cancer cell survival after irradiation or HMG CoA reductase inhibitor treatment.
|
Mol Pharmacol
|
2006
|
0.77
|
|
69
|
Two- and three-dimensional live cell imaging of DNA damage response proteins.
|
J Vis Exp
|
2012
|
0.76
|
|
70
|
Tracking the processing of damaged DNA double-strand break ends by ligation-mediated PCR: increased persistence of 3'-phosphoglycolate termini in SCAN1 cells.
|
Nucleic Acids Res
|
2013
|
0.76
|
|
71
|
Correction: Mutation of the BRCA1 SQ-cluster results in aberrant mitosis, reduced homologous recombination, and a compensatory increase in non-homologous end joining.
|
Oncotarget
|
2016
|
0.75
|
|
72
|
Editor's Note: /Syntenin: A Positive Regulator of Melanoma Metastasis.
|
Cancer Res
|
2019
|
0.75
|