Innovative approaches to the clinical development of DNA methylation inhibitors as epigenetic remodeling drugs.

Early epigenetic changes and DNA damage do not predict clinical response in an overlapping schedule of 5-azacytidine and entinostat in patients with myeloid malignancies. Blood (2009) 3.35

Reduced C9orf72 gene expression in c9FTD/ALS is caused by histone trimethylation, an epigenetic event detectable in blood. Acta Neuropathol (2013) 1.52

Elicitation of T cell responses to histologically unrelated tumors by immunization with the novel cancer-testis antigen, brother of the regulator of imprinted sites. J Immunol (2007) 0.93

Role of protein tyrosine phosphatases in cancer. Prog Nucleic Acid Res Mol Biol (2006) 0.92

E-cadherin and gastric cancer: cause, consequence, and applications. Biomed Res Int (2014) 0.92

Chromosome 16q genes CDH1, CDH13 and ADAMTS18 are correlated and frequently methylated in human lymphoma. Oncol Lett (2016) 0.77

Deciphering the Epigenetic Code in Embryonic and Dental Pulp Stem Cells. Yale J Biol Med (2016) 0.76

Non-genetic transgenerational transmission of bipolar disorder: targeting DNA methyltransferases. Mol Psychiatry (2016) 0.75