| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
14,15-Epoxyeicosa-5(Z)-enoic acid: a selective epoxyeicosatrienoic acid antagonist that inhibits endothelium-dependent hyperpolarization and relaxation in coronary arteries.
|
Circ Res
|
2002
|
2.09
|
|
2
|
Epoxyeicosatrienoic and dihydroxyeicosatrienoic acids dilate human coronary arterioles via BK(Ca) channels: implications for soluble epoxide hydrolase inhibition.
|
Am J Physiol Heart Circ Physiol
|
2005
|
1.76
|
|
3
|
Retracted
Hypercholesterolemia enhances 15-lipoxygenase-mediated vasorelaxation and acetylcholine-induced hypotension.
|
Arterioscler Thromb Vasc Biol
|
2008
|
1.49
|
|
4
|
Steroid-producing cells regulate arterial tone of adrenal cortical arteries.
|
Endocrinology
|
2007
|
1.48
|
|
5
|
Endothelium-derived hyperpolarizing factor in human internal mammary artery is 11,12-epoxyeicosatrienoic acid and causes relaxation by activating smooth muscle BK(Ca) channels.
|
Circulation
|
2003
|
1.46
|
|
6
|
Retracted
Chronic hypoxia enhances 15-lipoxygenase-mediated vasorelaxation in rabbit arteries.
|
Am J Physiol Heart Circ Physiol
|
2008
|
1.44
|
|
7
|
Effects of the selective EET antagonist, 14,15-EEZE, on cardioprotection produced by exogenous or endogenous EETs in the canine heart.
|
Am J Physiol Heart Circ Physiol
|
2008
|
1.44
|
|
8
|
Cultured rat microglial cells synthesize the endocannabinoid 2-arachidonylglycerol, which increases proliferation via a CB2 receptor-dependent mechanism.
|
Mol Pharmacol
|
2004
|
1.40
|
|
9
|
Hydrogen peroxide inhibits cytochrome p450 epoxygenases: interaction between two endothelium-derived hyperpolarizing factors.
|
Circ Res
|
2007
|
1.36
|
|
10
|
Inhibition of cytochrome P450omega-hydroxylase: a novel endogenous cardioprotective pathway.
|
Circ Res
|
2004
|
1.36
|
|
11
|
Membrane-potential-dependent inhibition of platelet adhesion to endothelial cells by epoxyeicosatrienoic acids.
|
Arterioscler Thromb Vasc Biol
|
2004
|
1.35
|
|
12
|
Characterization of epoxyeicosatrienoic acid binding site in U937 membranes using a novel radiolabeled agonist, 20-125i-14,15-epoxyeicosa-8(Z)-enoic acid.
|
J Pharmacol Exp Ther
|
2008
|
1.35
|
|
13
|
2-arachidonoylglycerol: a novel inhibitor of androgen-independent prostate cancer cell invasion.
|
Cancer Res
|
2004
|
1.30
|
|
14
|
14,15-epoxyeicosa-5(Z)-enoic-mSI: a 14,15- and 5,6-EET antagonist in bovine coronary arteries.
|
Hypertension
|
2003
|
1.29
|
|
15
|
Bradykinin-induced, endothelium-dependent responses in porcine coronary arteries: involvement of potassium channel activation and epoxyeicosatrienoic acids.
|
Br J Pharmacol
|
2005
|
1.28
|
|
16
|
Beyond vasodilatation: non-vasomotor roles of epoxyeicosatrienoic acids in the cardiovascular system.
|
Trends Pharmacol Sci
|
2006
|
1.28
|
|
17
|
Chronic hypoxia activates lung 15-lipoxygenase, which catalyzes production of 15-HETE and enhances constriction in neonatal rabbit pulmonary arteries.
|
Circ Res
|
2003
|
1.27
|
|
18
|
Comparison of vasodilatory properties of 14,15-EET analogs: structural requirements for dilation.
|
Am J Physiol Heart Circ Physiol
|
2002
|
1.24
|
|
19
|
The general anesthetic propofol increases brain N-arachidonylethanolamine (anandamide) content and inhibits fatty acid amide hydrolase.
|
Br J Pharmacol
|
2003
|
1.22
|
|
20
|
Cytochrome P450 omega-hydroxylase inhibition reduces infarct size during reperfusion via the sarcolemmal KATP channel.
|
J Mol Cell Cardiol
|
2004
|
1.18
|
|
21
|
Epoxy-keto derivative of linoleic acid stimulates aldosterone secretion.
|
Hypertension
|
2004
|
1.17
|
|
22
|
Characterization of 14,15-epoxyeicosatrienoyl-sulfonamides as 14,15-epoxyeicosatrienoic acid agonists: use for studies of metabolism and ligand binding.
|
J Pharmacol Exp Ther
|
2007
|
1.16
|
|
23
|
Asymmetric synthesis of the stereoisomers of 11,12,15(S)-trihydroxyeicosa-5(Z),8(Z),13(E)-trienoic acid, a potent endothelium-derived vasodilator.
|
Bioorg Med Chem Lett
|
2004
|
1.14
|
|
24
|
14,15-EET analogs: characterization of structural requirements for agonist and antagonist activity in bovine coronary arteries.
|
Pharmacol Res
|
2004
|
1.13
|
|
25
|
Role of FKBP12.6 in cADPR-induced activation of reconstituted ryanodine receptors from arterial smooth muscle.
|
Am J Physiol Heart Circ Physiol
|
2002
|
1.11
|
|
26
|
Vascular pharmacology of epoxyeicosatrienoic acids.
|
Adv Pharmacol
|
2010
|
1.11
|
|
27
|
ACh-induced relaxations of rabbit small mesenteric arteries: role of arachidonic acid metabolites and K+.
|
Am J Physiol Heart Circ Physiol
|
2007
|
1.09
|
|
28
|
Expression and function of fatty acid amide hydrolase in prostate cancer.
|
Int J Cancer
|
2008
|
1.09
|
|
29
|
14,15-Epoxyeicosa-5,8,11-trienoic acid (14,15-EET) surrogates containing epoxide bioisosteres: influence upon vascular relaxation and soluble epoxide hydrolase inhibition.
|
J Med Chem
|
2009
|
1.08
|
|
30
|
Endothelium-derived 2-arachidonylglycerol: an intermediate in vasodilatory eicosanoid release in bovine coronary arteries.
|
Am J Physiol Heart Circ Physiol
|
2004
|
1.08
|
|
31
|
Diverse roles of 2-arachidonoylglycerol in invasion of prostate carcinoma cells: Location, hydrolysis and 12-lipoxygenase metabolism.
|
Int J Cancer
|
2007
|
1.07
|
|
32
|
Angiotensin II-induced vascular smooth muscle cell migration and growth are mediated by cytochrome P450 1B1-dependent superoxide generation.
|
Hypertension
|
2010
|
1.06
|
|
33
|
Evidence for role of epoxyeicosatrienoic acids in mediating ischemic preconditioning and postconditioning in dog.
|
Am J Physiol Heart Circ Physiol
|
2009
|
1.04
|
|
34
|
Simultaneous in situ monitoring of intracellular Ca2+ and NO in endothelium of coronary arteries.
|
Am J Physiol Heart Circ Physiol
|
2002
|
1.04
|
|
35
|
14,15-epoxyeicosatrienoic acid represents a transferable endothelium-dependent relaxing factor in bovine coronary arteries.
|
Hypertension
|
2005
|
1.03
|
|
36
|
Role of arachidonic acid lipoxygenase metabolites in the regulation of vascular tone.
|
Am J Physiol Heart Circ Physiol
|
2009
|
1.01
|
|
37
|
Simultaneous analysis of angiotensin peptides by LC-MS and LC-MS/MS: metabolism by bovine adrenal endothelial cells.
|
Anal Biochem
|
2007
|
1.00
|
|
38
|
Liquid chromatographic-mass spectrometric determination of cyclooxygenase metabolites of arachidonic acid in cultured cells.
|
J Chromatogr B Analyt Technol Biomed Life Sci
|
2003
|
1.00
|
|
39
|
Identification of 15-hydroxy-11,12-epoxyeicosatrienoic acid as a vasoactive 15-lipoxygenase metabolite in rabbit aorta.
|
Am J Physiol Heart Circ Physiol
|
2008
|
1.00
|
|
40
|
ROCK1 feedback regulation of the upstream small GTPase RhoA.
|
Cell Signal
|
2012
|
1.00
|
|
41
|
Roles of epoxyeicosatrienoic acids in vascular regulation and cardiac preconditioning.
|
J Cardiovasc Pharmacol
|
2007
|
0.99
|
|
42
|
A new class of inhibitors of 2-arachidonoylglycerol hydrolysis and invasion of prostate cancer cells.
|
Biochem Biophys Res Commun
|
2005
|
0.98
|
|
43
|
Cytochrome P450 1B1 contributes to renal dysfunction and damage caused by angiotensin II in mice.
|
Hypertension
|
2011
|
0.97
|
|
44
|
Reticulocyte 15-lipoxygenase-I is important in acetylcholine-induced endothelium-dependent vasorelaxation in rabbit aorta.
|
Arterioscler Thromb Vasc Biol
|
2005
|
0.96
|
|
45
|
Cannabinoid receptor type 1 (CB1) activation inhibits small GTPase RhoA activity and regulates motility of prostate carcinoma cells.
|
Endocrinology
|
2011
|
0.96
|
|
46
|
Apamin-sensitive K+ currents mediate arachidonic acid-induced relaxations of rabbit aorta.
|
Hypertension
|
2003
|
0.95
|
|
47
|
Cyclic ADP-ribose contributes to contraction and Ca2+ release by M1 muscarinic receptor activation in coronary arterial smooth muscle.
|
J Vasc Res
|
2003
|
0.95
|
|
48
|
Effects of selective inhibition of cytochrome P-450 omega-hydroxylases and ischemic preconditioning in myocardial protection.
|
Am J Physiol Heart Circ Physiol
|
2005
|
0.94
|
|
49
|
Elevated 12- and 20-hydroxyeicosatetraenoic acid in urine of patients with prostatic diseases.
|
Cancer Lett
|
2006
|
0.94
|
|
50
|
A role for heterocellular coupling and EETs in dilation of rat cremaster arteries.
|
Microcirculation
|
2006
|
0.94
|
|
51
|
20-hydroxyeicosatetraenoic acid (20-HETE) metabolism in coronary endothelial cells.
|
J Biol Chem
|
2003
|
0.91
|
|
52
|
Studies of anandamide accumulation inhibitors in cerebellar granule neurons: comparison to inhibition of fatty acid amide hydrolase.
|
J Mol Neurosci
|
2007
|
0.91
|
|
53
|
11(R),12(S),15(S)-trihydroxyeicosa-5(Z),8(Z),13(E)-trienoic acid: an endothelium-derived 15-lipoxygenase metabolite that relaxes rabbit aorta.
|
Am J Physiol Heart Circ Physiol
|
2008
|
0.91
|
|
54
|
Mice lacking macrophage 12/15-lipoxygenase are resistant to experimental hypertension.
|
Am J Physiol Heart Circ Physiol
|
2012
|
0.90
|
|
55
|
Stable 5,6-epoxyeicosatrienoic acid analog relaxes coronary arteries through potassium channel activation.
|
Hypertension
|
2005
|
0.89
|
|
56
|
Epoxyeicosatrienoic acid analogue lowers blood pressure through vasodilation and sodium channel inhibition.
|
Clin Sci (Lond)
|
2014
|
0.89
|
|
57
|
Role of arachidonic acid lipoxygenase metabolites in acetylcholine-induced relaxations of mouse arteries.
|
Am J Physiol Heart Circ Physiol
|
2010
|
0.88
|
|
58
|
20-Iodo-14,15-epoxyeicosa-8(Z)-enoyl-3-azidophenylsulfonamide: photoaffinity labeling of a 14,15-epoxyeicosatrienoic acid receptor.
|
Biochemistry
|
2011
|
0.88
|
|
59
|
Endostatin uncouples NO and Ca2+ response to bradykinin through enhanced O2*- production in the intact coronary endothelium.
|
Am J Physiol Heart Circ Physiol
|
2004
|
0.88
|
|
60
|
20-125Iodo-14,15-epoxyeicosa-5(Z)-enoic acid: a high-affinity radioligand used to characterize the epoxyeicosatrienoic acid antagonist binding site.
|
J Pharmacol Exp Ther
|
2009
|
0.88
|
|
61
|
Endothelial 15-lipoxygenase-1 overexpression increases acetylcholine-induced hypotension and vasorelaxation in rabbits.
|
Hypertension
|
2008
|
0.88
|
|
62
|
Involvement of cytochrome P-450 1B1 in renal dysfunction, injury, and inflammation associated with angiotensin II-induced hypertension in rats.
|
Am J Physiol Renal Physiol
|
2011
|
0.88
|
|
63
|
Role of ADP-ribose in 11,12-EET-induced activation of K(Ca) channels in coronary arterial smooth muscle cells.
|
Am J Physiol Heart Circ Physiol
|
2002
|
0.87
|
|
64
|
Effects of epoxyeicosatrienoic acids on polymorphonuclear leukocyte function.
|
Life Sci
|
2002
|
0.87
|
|
65
|
Inhibition of carcinoma cell motility by epoxyeicosatrienoic acid (EET) antagonists.
|
Cancer Sci
|
2010
|
0.87
|
|
66
|
Rabbit aorta converts 15-HPETE to trihydroxyeicosatrienoic acids: potential role of cytochrome P450.
|
Arch Biochem Biophys
|
2003
|
0.87
|
|
67
|
Anti-proliferative effect of a putative endocannabinoid, 2-arachidonylglyceryl ether in prostate carcinoma cells.
|
Prostaglandins Other Lipid Mediat
|
2010
|
0.87
|
|
68
|
Metabolism of adrenic acid to vasodilatory 1alpha,1beta-dihomo-epoxyeicosatrienoic acids by bovine coronary arteries.
|
Am J Physiol Heart Circ Physiol
|
2007
|
0.86
|
|
69
|
Role of phospholipase C and diacylglyceride lipase pathway in arachidonic acid release and acetylcholine-induced vascular relaxation in rabbit aorta.
|
Am J Physiol Heart Circ Physiol
|
2005
|
0.86
|
|
70
|
Arachidonic acid-induced dilation in human coronary arterioles: convergence of signaling mechanisms on endothelial TRPV4-mediated Ca2+ entry.
|
J Am Heart Assoc
|
2013
|
0.86
|
|
71
|
Novel mechanism of vasodilation in inflammatory bowel disease.
|
Arterioscler Thromb Vasc Biol
|
2005
|
0.86
|
|
72
|
Metabolism of 12-hydroperoxyeicosatetraenoic acid to vasodilatory trioxilin C3 by rabbit aorta.
|
Biochim Biophys Acta
|
2003
|
0.85
|
|
73
|
Cytochrome P450 1B1 gene disruption minimizes deoxycorticosterone acetate-salt-induced hypertension and associated cardiac dysfunction and renal damage in mice.
|
Hypertension
|
2012
|
0.85
|
|
74
|
Angiotensin II dilates bovine adrenal cortical arterioles: role of endothelial nitric oxide.
|
Endocrinology
|
2005
|
0.85
|
|
75
|
Characterization of vasoconstrictor responses in small bovine adrenal cortical arteries in vitro.
|
Endocrinology
|
2004
|
0.85
|
|
76
|
Angiotensin II relaxations of bovine adrenal cortical arteries: role of angiotensin II metabolites and endothelial nitric oxide.
|
Hypertension
|
2008
|
0.84
|
|
77
|
Adenoviral expression of 15-lipoxygenase-1 in rabbit aortic endothelium: role in arachidonic acid-induced relaxation.
|
Am J Physiol Heart Circ Physiol
|
2006
|
0.84
|
|
78
|
Cyclooxygenase- and lipoxygenase-dependent relaxation to arachidonic acid in rabbit small mesenteric arteries.
|
Am J Physiol Heart Circ Physiol
|
2004
|
0.84
|
|
79
|
Characterization and application of Raman labels for confocal Raman microspectroscopic detection of cellular proteins in single cells.
|
Anal Biochem
|
2003
|
0.84
|
|
80
|
Chiral resolution of the epoxyeicosatrienoic acids, arachidonic acid epoxygenase metabolites.
|
Anal Biochem
|
2006
|
0.83
|
|
81
|
Structural characterization of monohydroxyeicosatetraenoic acids and dihydroxy- and trihydroxyeicosatrienoic acids by ESI-FTICR.
|
J Am Soc Mass Spectrom
|
2008
|
0.83
|
|
82
|
Prologue: kinins and related systems. New life for old discoveries.
|
Am J Physiol Heart Circ Physiol
|
2003
|
0.82
|
|
83
|
Endothelial 12(S)-HETE vasorelaxation is mediated by thromboxane receptor inhibition in mouse mesenteric arteries.
|
Am J Physiol Heart Circ Physiol
|
2012
|
0.82
|
|
84
|
Ecto-5'-nucleotidase, CD73, is an endothelium-derived hyperpolarizing factor synthase.
|
Arterioscler Thromb Vasc Biol
|
2013
|
0.81
|
|
85
|
Role of contaminating platelets in thromboxane synthesis in primary cultures of human umbilical vein endothelial cells.
|
Prostaglandins Other Lipid Mediat
|
2002
|
0.81
|
|
86
|
Identification and characterization of the unique guanine nucleotide exchange factor, SmgGDS, in vascular smooth muscle cells.
|
J Cell Biochem
|
2008
|
0.81
|
|
87
|
14,15-Dihydroxy-eicosa-5(Z)-enoic acid selectively inhibits 14,15-epoxyeicosatrienoic acid-induced relaxations in bovine coronary arteries.
|
J Pharmacol Exp Ther
|
2010
|
0.81
|
|
88
|
Role of superoxide and thromboxane receptors in acute angiotensin II-induced vasoconstriction of rabbit vessels.
|
Am J Physiol Heart Circ Physiol
|
2011
|
0.80
|
|
89
|
Effect of human 15-lipoxygenase-1 metabolites on vascular function in mouse mesenteric arteries and hearts.
|
Prostaglandins Other Lipid Mediat
|
2013
|
0.80
|
|
90
|
11,12,20-Trihydroxy-eicosa-8(Z)-enoic acid: a selective inhibitor of 11,12-EET-induced relaxations of bovine coronary and rat mesenteric arteries.
|
Am J Physiol Heart Circ Physiol
|
2012
|
0.80
|
|
91
|
ACE inhibition enhances bradykinin relaxations through nitric oxide and B1 receptor activation in bovine coronary arteries.
|
Biol Chem
|
2013
|
0.80
|
|
92
|
Induction of human cholesterol 7alpha-hydroxylase in HepG2 cells by 2,4,6-trihydroxyacetophenone.
|
Eur J Pharmacol
|
2005
|
0.80
|
|
93
|
Glibenclamide inhibits thromboxane-mediated vasoconstriction by thromboxane receptor blockade.
|
Vascul Pharmacol
|
2004
|
0.80
|
|
94
|
15-Lipoxygenase metabolites contribute to age-related reduction in acetylcholine-induced hypotension in rabbits.
|
Am J Physiol Heart Circ Physiol
|
2008
|
0.80
|
|
95
|
Age-related decrease in 15-lipoxygenase contributes to reduced vasorelaxation in rabbit aorta.
|
Am J Physiol Heart Circ Physiol
|
2007
|
0.80
|
|
96
|
Protein methylation activates reconstituted ryanodine receptor-ca release channels from coronary artery myocytes.
|
J Vasc Res
|
2004
|
0.79
|
|
97
|
Identification of 13-hydroxy-14,15-epoxyeicosatrienoic acid as an acid-stable endothelium-derived hyperpolarizing factor in rabbit arteries.
|
J Biol Chem
|
2009
|
0.79
|
|
98
|
Interleukin-13 upregulates vasodilatory 15-lipoxygenase eicosanoids in rabbit aorta.
|
Arterioscler Thromb Vasc Biol
|
2003
|
0.79
|
|
99
|
Soluble epoxide hydrolase contamination of specific catalase preparations inhibits epoxyeicosatrienoic acid vasodilation of rat renal arterioles.
|
Am J Physiol Renal Physiol
|
2011
|
0.78
|
|
100
|
Angiotensin II and III metabolism and effects on steroid production in the HAC15 human adrenocortical cell line.
|
Endocrinology
|
2012
|
0.78
|
|
101
|
Endothelium-derived steroidogenic factor enhances angiotensin II-stimulated aldosterone release by bovine zona glomerulosa cells.
|
Endocrinology
|
2006
|
0.78
|
|
102
|
Angiotensin II regulates adrenal vascular tone through zona glomerulosa cell-derived EETs and DHETs.
|
Hypertension
|
2011
|
0.78
|
|
103
|
Adrenic acid metabolites as endogenous endothelium-derived and zona glomerulosa-derived hyperpolarizing factors.
|
Hypertension
|
2009
|
0.78
|
|
104
|
14,15-Epoxyeicosa-5,8,11-trienoic Acid (14,15-EET) surrogates: carboxylate modifications.
|
J Med Chem
|
2014
|
0.77
|
|
105
|
Endothelial metabolism of angiotensin II to angiotensin III, not angiotensin (1-7), augments the vasorelaxation response in adrenal cortical arteries.
|
Endocrinology
|
2013
|
0.77
|
|
106
|
Reduced expression of 15-lipoxygenase 2 in human head and neck carcinomas.
|
Tumour Biol
|
2006
|
0.77
|
|
107
|
Mechanisms of histamine-induced relaxation in bovine small adrenal cortical arteries.
|
Am J Physiol Endocrinol Metab
|
2005
|
0.77
|
|
108
|
Determination of cyclooxygenase and arachidonic acid metabolites in invasive human prostate cancer cells.
|
Adv Exp Med Biol
|
2002
|
0.77
|
|
109
|
Role of macrophage PPARγ in experimental hypertension.
|
Am J Physiol Heart Circ Physiol
|
2013
|
0.76
|
|
110
|
Aldosterone secretagogues increase adrenal blood flow in male rats.
|
Endocrinology
|
2013
|
0.76
|
|
111
|
Acetylcholine-induced relaxation and hyperpolarization in small bovine adrenal cortical arteries: role of cytochrome P450 metabolites.
|
Endocrinology
|
2004
|
0.76
|
|
112
|
Epoxygenase eicosanoids: synthesis of tetrahydrofuran-diol metabolites and their vasoactivity.
|
Bioorg Med Chem Lett
|
2007
|
0.76
|
|
113
|
Endothelial nitric oxide and 15-lipoxygenase-1 metabolites independently mediate relaxation of the rabbit aorta.
|
Vascul Pharmacol
|
2011
|
0.76
|
|
114
|
Measurement of steroid synthesis in zona glomerulosa cells by liquid chromatography-electrospray ionization-mass spectrometry: inhibition by nitric oxide.
|
Anal Biochem
|
2005
|
0.76
|
|
115
|
Production of hydroxyeicosatetraenoic acids and prostaglandins by a novel rat microglial cell line.
|
J Neuroimmunol
|
2004
|
0.75
|
|
116
|
Chronic administration of nitric oxide reduces angiotensin II receptor type 1 expression and aldosterone synthesis in zona glomerulosa cells.
|
Am J Physiol Endocrinol Metab
|
2004
|
0.75
|
|
117
|
Adrenal Capillary Endothelial Cells Stimulate Aldosterone Release through a Protein That Is Distinct from Endothelin1.
|
Endocrinology
|
1999
|
0.75
|
|
118
|
Eicosanoids and disease. Introduction.
|
Prostaglandins Other Lipid Mediat
|
2011
|
0.75
|
|
119
|
Development of enzyme immunoassays for 5,6-, 8,9-, 11,12-, and 14,15- EETs and the corresponding DHETs.
|
Adv Exp Med Biol
|
2002
|
0.75
|