Published in J Am Chem Soc on November 02, 2005
Fluorescence-activated cell sorting for aptamer SELEX with cell mixtures. Nat Protoc (2010) 1.28
Site-specific labeling of DNA and RNA using an efficiently replicated and transcribed class of unnatural base pairs. J Am Chem Soc (2011) 1.19
A self-cleaving DNA enzyme modified with amines, guanidines and imidazoles operates independently of divalent metal cations (M2+). Nucleic Acids Res (2009) 1.12
Systematic characterization of 2'-deoxynucleoside- 5'-triphosphate analogs as substrates for DNA polymerases by polymerase chain reaction and kinetic studies on enzymatic production of modified DNA. Nucleic Acids Res (2006) 0.98
CyDNA: synthesis and replication of highly Cy-dye substituted DNA by an evolved polymerase. J Am Chem Soc (2010) 0.95
Sensing metal ions with DNA building blocks: fluorescent pyridobenzimidazole nucleosides. J Am Chem Soc (2006) 0.93
Expanding the substrate tolerance of biotin ligase through exploration of enzymes from diverse species. J Am Chem Soc (2008) 0.91
Systematic analysis of enzymatic DNA polymerization using oligo-DNA templates and triphosphate analogs involving 2',4'-bridged nucleosides. Nucleic Acids Res (2008) 0.90
High density labeling of polymerase chain reaction products with the fluorescent base analogue tCo. Anal Chem (2009) 0.89
DNA ligase-mediated translation of DNA into densely functionalized nucleic acid polymers. J Am Chem Soc (2012) 0.89
Mechanical properties of DNA-like polymers. Nucleic Acids Res (2013) 0.89
Towards XNA nanotechnology: new materials from synthetic genetic polymers. Trends Biotechnol (2014) 0.89
DNA modification under mild conditions by Suzuki-Miyaura cross-coupling for the generation of functional probes. Angew Chem Int Ed Engl (2013) 0.88
Structural basis for the synthesis of nucleobase modified DNA by Thermus aquaticus DNA polymerase. Proc Natl Acad Sci U S A (2010) 0.86
Enzymatic incorporation of emissive pyrimidine ribonucleotides. Chem Asian J (2009) 0.84
Enzymatic incorporation of an azide-modified UTP analog into oligoribonucleotides for post-transcriptional chemical functionalization. Nat Protoc (2012) 0.83
Artificial specific binders directly recovered from chemically modified nucleic acid libraries. J Nucleic Acids (2012) 0.81
In vitro selection using modified or unnatural nucleotides. Curr Protoc Nucleic Acid Chem (2002) 0.81
Mechanical properties of base-modified DNA are not strictly determined by base stacking or electrostatic interactions. Biophys J (2014) 0.81
Cleavage of adenine-modified functionalized DNA by type II restriction endonucleases. Nucleic Acids Res (2009) 0.80
Rigid cyanine dye nucleic acid labels. Chem Commun (Camb) (2008) 0.79
Isolation of Foreign Material-Free Endothelial Progenitor Cells Using CD31 Aptamer and Therapeutic Application for Ischemic Injury. PLoS One (2015) 0.78
Enzymatic Synthesis of Sequence-Defined Synthetic Nucleic Acid Polymers with Diverse Functional Groups. Angew Chem Int Ed Engl (2016) 0.78
Unnatural imidazopyridopyrimidine:naphthyridine base pairs: selective incorporation and extension reaction by Deep Vent (exo- ) DNA polymerase. Nucleic Acids Res (2009) 0.76
In vitro selection using modified or unnatural nucleotides. Curr Protoc Nucleic Acid Chem (2014) 0.76
Structure-activity relationships of the ATP cofactor in ligase-catalysed oligonucleotide polymerisations. Org Biomol Chem (2017) 0.75
Versatile synthesis of amino acid functionalized nucleosides via a domino carboxamidation reaction. Beilstein J Org Chem (2014) 0.75
Nucleoside triphosphates--from synthesis to biochemical characterization. J Vis Exp (2014) 0.75
Laboratory evolution of artificially expanded DNA gives redesignable aptamers that target the toxic form of anthrax protective antigen. Nucleic Acids Res (2016) 0.75
Efficient enzymatic synthesis and dual-colour fluorescent labelling of DNA probes using long chain azido-dUTP and BCN dyes. Nucleic Acids Res (2016) 0.75
Azidophenyl as a click-transformable redox label of DNA suitable for electrochemical detection of DNA-protein interactions. Chem Sci (2014) 0.75
Biomolecular engineering for nanobio/bionanotechnology. Nano Converg (2017) 0.75
Retracted Cytohesins are cytoplasmic ErbB receptor activators. Cell (2010) 2.74
Inhibition of cytohesins by SecinH3 leads to hepatic insulin resistance. Nature (2006) 2.40
Protein-dependent ribozymes report molecular interactions in real time. Nat Biotechnol (2002) 2.00
The nuclear receptor PPAR gamma selectively inhibits Th17 differentiation in a T cell-intrinsic fashion and suppresses CNS autoimmunity. J Exp Med (2009) 1.95
Slit2-Robo4 signalling promotes vascular stability by blocking Arf6 activity. Nat Cell Biol (2009) 1.73
Aptamer displacement identifies alternative small-molecule target sites that escape viral resistance. Chem Biol (2007) 1.52
Repression of the genome organizer SATB1 in regulatory T cells is required for suppressive function and inhibition of effector differentiation. Nat Immunol (2011) 1.49
GGA proteins regulate retrograde transport of BACE1 from endosomes to the trans-Golgi network. Mol Cell Neurosci (2005) 1.47
Enrichment of cell-targeting and population-specific aptamers by fluorescence-activated cell sorting. Angew Chem Int Ed Engl (2008) 1.35
Prion-protein-specific aptamer reduces PrPSc formation. Chembiochem (2002) 1.35
Fluorescence-activated cell sorting for aptamer SELEX with cell mixtures. Nat Protoc (2010) 1.28
Sequence-specific detection of MicroRNAs by signal-amplifying ribozymes. J Am Chem Soc (2004) 1.26
GGA1 is expressed in the human brain and affects the generation of amyloid beta-peptide. J Neurosci (2006) 1.20
Aptamers for allosteric regulation. Nat Chem Biol (2011) 1.19
Conformational changes in the expression domain of the Escherichia coli thiM riboswitch. Nucleic Acids Res (2007) 1.17
A double-stranded DNA rotaxane. Nat Nanotechnol (2010) 1.16
Structure of an RNA polymerase II-RNA inhibitor complex elucidates transcription regulation by noncoding RNAs. Nat Struct Mol Biol (2005) 1.14
An aptamer targeting the apical-loop domain modulates pri-miRNA processing. Angew Chem Int Ed Engl (2010) 1.09
Identification and in vitro analysis of the GatD/MurT enzyme-complex catalyzing lipid II amidation in Staphylococcus aureus. PLoS Pathog (2012) 1.06
High-throughput-compatible assay for glmS riboswitch metabolite dependence. Chembiochem (2006) 1.02
Discriminatory aptamer reveals serum response element transcription regulated by cytohesin-2. Proc Natl Acad Sci U S A (2004) 1.02
A novel class of small functional peptides that bind and inhibit human alpha-thrombin isolated by mRNA display. Chem Biol (2003) 1.00
A ribozyme for the aldol reaction. Chem Biol (2005) 1.00
Light-induced formation of G-quadruplex DNA secondary structures. Chembiochem (2005) 0.99
Chemical biology: aptamers in nanoland. Nature (2006) 0.99
A Y2 receptor mimetic aptamer directed against neuropeptide Y. J Biol Chem (2001) 0.98
Functionalized DNA: A New Replicable Biopolymer We thank Dr. Andreas Marx, University of Bonn, for helpful advice and discussions. This work was supported by the Fonds der Chemischen Industrie, the Karl-Ziegler Stiftung, and the Deutsche Forschungsgemeinschaft. Angew Chem Int Ed Engl (2001) 0.97
Grp1 plays a key role in linking insulin signaling to glut4 recycling. Dev Cell (2012) 0.96
Pederin-type pathways of uncultivated bacterial symbionts: analysis of o-methyltransferases and generation of a biosynthetic hybrid. J Am Chem Soc (2009) 0.96
The final steps of bacillaene biosynthesis in Bacillus amyloliquefaciens FZB42: direct evidence for beta,gamma dehydration by a trans-acyltransferase polyketide synthase. Angew Chem Int Ed Engl (2010) 0.96
Generation and enzymatic amplification of high-density functionalized DNA double strands. Angew Chem Int Ed Engl (2004) 0.95
Self-assembly reactions between the cis-protected metal corners (N-N)MII (N-N = ethylenediamine, 4,4'-substituted 2,2'-bipyridine; M = Pd, Pt) and the fluorinated edge 1,4-bis(4-pyridyl)tetrafluorobenzene. Inorg Chem (2007) 0.94
RNA aptamers selectively modulate protein recruitment to the cytoplasmic domain of beta-secretase BACE1 in vitro. RNA (2006) 0.94
Heteromerization of innexin gap junction proteins regulates epithelial tissue organization in Drosophila. Mol Biol Cell (2006) 0.93
Displacement of protein-bound aptamers with small molecules screened by fluorescence polarization. Nat Protoc (2008) 0.92
RNA ligands that distinguish metabolite-induced conformations in the TPP riboswitch. Angew Chem Int Ed Engl (2007) 0.91
The metagenome-derived enzymes LipS and LipT increase the diversity of known lipases. PLoS One (2012) 0.90
Reversible light switch for macrocycle mobility in a DNA rotaxane. J Am Chem Soc (2012) 0.89
Aptamer-based affinity labeling of proteins. Angew Chem Int Ed Engl (2012) 0.88
Construction of DNA architectures with RNA hairpins. Angew Chem Int Ed Engl (2008) 0.88
Room-temperature C-H bond activation of methane by bare [P(4)O(10)](*+). Angew Chem Int Ed Engl (2009) 0.88
Polyamide struts for DNA architectures. Angew Chem Int Ed Engl (2007) 0.87
I-motif-programmed functionalization of DNA nanocircles. J Am Chem Soc (2013) 0.86
A selective inhibitor of heme biosynthesis in endosymbiotic bacteria elicits antifilarial activity in vitro. Chem Biol (2013) 0.86
Cleavage of four carbon-carbon bonds during biosynthesis of the griseorhodin a spiroketal pharmacophore. J Am Chem Soc (2009) 0.85
DNA minicircles with gaps for versatile functionalization. Angew Chem Int Ed Engl (2008) 0.85
Chemical biology: ignore the nonsense. Nature (2007) 0.85
Design strategy for DNA rotaxanes with a mechanically reinforced PX100 axle. Angew Chem Int Ed Engl (2012) 0.84
Input-dependent induction of oligonucleotide structural motifs for performing molecular logic. J Am Chem Soc (2012) 0.83
Characterization of self-assembled metallodendrimers in solution, in the gas phase, and at air/solid interfaces. Small (2008) 0.83
New chemotypes for wALADin1-like inhibitors of delta-aminolevulinic acid dehydratase from Wolbachia endobacteria. Bioorg Med Chem Lett (2013) 0.83
Logic gating by macrocycle displacement using a double-stranded DNA [3]rotaxane shuttle. Angew Chem Int Ed Engl (2014) 0.83
Aptamers that recognize the lipid moiety of the antibiotic moenomycin A. Biol Chem (2003) 0.83
Affinity-based labeling of cytohesins with a bifunctional SecinH3 photoaffinity probe. Angew Chem Int Ed Engl (2008) 0.82
Targeting multifunctional proteins by virtual screening: structurally diverse cytohesin inhibitors with differentiated biological functions. ACS Chem Biol (2010) 0.82
Pseudo-complementary PNA actuators as reversible switches in dynamic DNA nanotechnology. Nucleic Acids Res (2013) 0.82
Specific targeting of ultrasound contrast agent (USCA) for diagnostic application: an in vitro feasibility study based on SAW biosensor. Biosens Bioelectron (2005) 0.82
A homogeneous fluorescence resonance energy transfer system for monitoring the activation of a protein switch in real time. J Am Chem Soc (2011) 0.82
Cancer vaccine enhanced, non-tumor-reactive CD8(+) T cells exhibit a distinct molecular program associated with "division arrest anergy". Cancer Res (2009) 0.82
Sensing complex regulatory networks by conformationally controlled hairpin ribozymes. Nucleic Acids Res (2004) 0.81
Discrimination of single mutations in cancer-related gene fragments with a surface acoustic wave sensor. Anal Chem (2006) 0.81
ADLOC: an aptamer-displacement assay based on luminescent oxygen channeling. Chemistry (2010) 0.81
Cyplecksins are covalent inhibitors of the pleckstrin homology domain of cytohesin. Angew Chem Int Ed Engl (2013) 0.81
Mechanically interlocked DNA nanostructures for functional devices. Acc Chem Res (2014) 0.81
Synthesis of axially chiral 4,4'-bipyridines and their remarkably selective self-assembly into chiral metallo-supramolecular squares. Chemistry (2008) 0.81
Self-assembling squares with amino acid-decorated bipyridines: heterochiral self-sorting of dynamically interconverting diastereomers. Chem Commun (Camb) (2008) 0.81
Reporter ribozymes for real-time analysis of domain-specific interactions in biomolecules: HIV-1 reverse transcriptase and the primer-template complex. Angew Chem Int Ed Engl (2002) 0.81
Functional tuning of nucleic acids by chemical modifications: tailored oligonucleotides as drugs, devices, and diagnostics. Chem Rec (2003) 0.81
Immobilised lipases in the cosmetics industry. Chem Soc Rev (2013) 0.81
Anti-proliferative effect of cytohesin inhibition in gefitinib-resistant lung cancer cells. PLoS One (2012) 0.80
Switchable reconfiguration of an interlocked DNA olympiadane nanostructure. Angew Chem Int Ed Engl (2014) 0.80
wALADin benzimidazoles differentially modulate the function of porphobilinogen synthase orthologs. J Med Chem (2014) 0.80
Enantiomerically pure [M(6)L(12)] or [M(12)L(24)] polyhedra from flexible bis(pyridine) ligands. Angew Chem Int Ed Engl (2014) 0.80
Online monitoring of biotransformations in high viscous multiphase systems by means of FT-IR and chemometrics. Anal Chem (2010) 0.79
Competitive regulation of modular allosteric aptazymes by a small molecule and oligonucleotide effector. RNA (2005) 0.79
Building objects from nucleic acids for a nanometer world. Biochimie (2008) 0.79
Secondary structures and functional requirements for thiM riboswitches from Desulfovibrio vulgaris, Erwinia carotovora and Rhodobacter spheroides. Biol Chem (2008) 0.78
Anti-innexin 2 aptamers specifically inhibit the heterologous interaction of the innexin 2 and innexin 3 carboxyl-termini in vitro. Biol Chem (2007) 0.78
Functional nucleic acids in high throughput screening and drug discovery. Comb Chem High Throughput Screen (2007) 0.78
Kinetic binding analysis of aptamers targeting HIV-1 proteins by a combination of a microbalance array and mass spectrometry (MAMS). J Proteome Res (2009) 0.78
Functional expression of porcine aminoacylase 1 in E. coli using a codon optimized synthetic gene and molecular chaperones. Appl Microbiol Biotechnol (2008) 0.78
A ribozyme with michaelase activity: synthesis of the substrate precursors. Bioorg Med Chem (2003) 0.78
Assembly of dsDNA nanocircles into dimeric and oligomeric aggregates. Chem Commun (Camb) (2010) 0.78
A novel family of structurally stable double stranded DNA catenanes. Chem Commun (Camb) (2014) 0.78
DNA aptamer-mediated regulation of the hairpin ribozyme by human alpha-thrombin. Blood Cells Mol Dis (2006) 0.78
Enantiomerically pure trinuclear helicates via diastereoselective self-assembly and characterization of their redox chemistry. J Am Chem Soc (2014) 0.77
Direct experimental evidence for an enamine radical cation in SOMO catalysis. Chem Commun (Camb) (2011) 0.77
In vitro selection of conformational probes for riboswitches. Methods Mol Biol (2009) 0.77
Screening of novel inhibitors of HIV-1 reverse transcriptase with a reporter ribozyme assay. Methods Mol Biol (2009) 0.77
DNA-based phosphane ligands. Chemistry (2007) 0.77
Photocleavable initiator nucleotide substrates for an aldolase ribozyme. J Org Chem (2008) 0.77
Cap for copper(I) ions! Metallosupramolecular solid and solution state structures on the basis of the dynamic tetrahedral [Cu(phenAr2)(py)2]+ motif. Inorg Chem (2009) 0.77
Competitive hydrogen-atom abstraction versus oxygen-atom and electron transfers in gas-phase reactions of [X4O10]·+ (X = P, V) with C2 H4. Chemistry (2010) 0.76
A trifluoromethylphenyl diazirine-based SecinH3 photoaffinity probe. Chem Commun (Camb) (2011) 0.76
Turning aptamers into anticoagulants. Nat Biotechnol (2004) 0.76