Published in J Viral Hepat on November 01, 2005
Oxidative stress and antioxidants in hepatic pathogenesis. World J Gastroenterol (2010) 1.40
Silymarin ascending multiple oral dosing phase I study in noncirrhotic patients with chronic hepatitis C. J Clin Pharmacol (2009) 1.37
Silybin and the liver: from basic research to clinical practice. World J Gastroenterol (2011) 1.27
Differential in vitro effects of intravenous versus oral formulations of silibinin on the HCV life cycle and inflammation. PLoS One (2011) 1.27
Effects of silybum marianum on patients with chronic hepatitis C. J Res Med Sci (2011) 1.15
Understanding silibinin's modes of action against HCV using viral kinetic modeling. J Hepatol (2012) 1.08
Silymarin use and liver disease progression in the Hepatitis C Antiviral Long-Term Treatment against Cirrhosis trial. Aliment Pharmacol Ther (2010) 1.04
"Silymarin", a promising pharmacological agent for treatment of diseases. Iran J Basic Med Sci (2011) 0.93
A randomized controlled trial to assess the safety and efficacy of silymarin on symptoms, signs and biomarkers of acute hepatitis. Phytomedicine (2009) 0.91
Hepatic metabolism and biliary excretion of silymarin flavonolignans in isolated perfused rat livers: role of multidrug resistance-associated protein 2 (Abcc2). Drug Metab Dispos (2008) 0.90
Rationale, challenges, and participants in a Phase II trial of a botanical product for chronic hepatitis C. Clin Trials (2011) 0.89
Silibinin inhibits VEGF secretion and age-related macular degeneration in a hypoxia-dependent manner through the PI-3 kinase/Akt/mTOR pathway. Br J Pharmacol (2013) 0.88
Hepatoprotective effect of commercial herbal extracts on carbon tetrachloride-induced liver damage in Wistar rats. Pharmacognosy Res (2013) 0.88
Severity of liver disease affects HCV kinetics in patients treated with intravenous silibinin monotherapy. Antivir Ther (2014) 0.82
Current Status of Herbal Medicines in Chronic Liver Disease Therapy: The Biological Effects, Molecular Targets and Future Prospects. Int J Mol Sci (2015) 0.81
An herbal formula, CGX, exerts hepatotherapeutic effects on dimethylnitrosamine-induced chronic liver injury model in rats. World J Gastroenterol (2006) 0.81
The effects of milk thistle on hepatic fibrosis due to methotrexate in rat. Hepat Mon (2011) 0.78
Efficacy of a galactogogue containing silymarin-phosphatidylserine and galega in mothers of preterm infants: a randomized controlled trial. Eur J Clin Nutr (2016) 0.77
Optimization and single-laboratory validation of a method for the determination of flavonolignans in milk thistle seeds by high-performance liquid chromatography with ultraviolet detection. Anal Bioanal Chem (2015) 0.75
Effect of indigenous herbs on growth, blood metabolites and carcass characteristics in the late fattening period of hanwoo steers. Asian-Australas J Anim Sci (2013) 0.75
Antioxidant and Anti-Hepatitis C Viral Activities of Commercial Milk Thistle Food Supplements. Antioxidants (Basel) (2013) 0.75
Free Radical Scavenging and Antioxidant Activities of Silymarin Components. Antioxidants (Basel) (2013) 0.75
Ultrasonic-assisted enzymatic extraction of silymarin from the Silybum marianum seed shell and evaluation of its antioxidant activity in vitro. EXCLI J (2015) 0.75
Is herbal medicine effective in the management of patients with chronic hepatitis C? J Res Med Sci (2011) 0.75
Anti-fibro-hepatocarcinogenic Chinese herbal medicines: A mechanistic overview. J Intercult Ethnopharmacol (2016) 0.75
Hepatoprotective effects of the nitric oxide donor isosorbide-5-mononitrate alone and in combination with the natural hepatoprotectant, silymarin, on carbon tetrachloride-induced hepatic injury in rats. Inflammopharmacology (2010) 0.75
Primary liver abscess due to Klebsiella pneumoniae in Taiwan. Clin Infect Dis (1998) 7.51
Immune system impairment and hepatic fibrosis in mice lacking the dioxin-binding Ah receptor. Science (1995) 6.03
Synthesis of highly crystalline and monodisperse maghemite nanocrystallites without a size-selection process. J Am Chem Soc (2001) 4.28
Delineating Patterns of Medical Care. Am J Public Health Nations Health (1960) 4.11
Molecular mechanisms underlying chemopreventive activities of anti-inflammatory phytochemicals: down-regulation of COX-2 and iNOS through suppression of NF-kappa B activation. Mutat Res (2001) 3.94
Peginterferon alfa-2a in patients with chronic hepatitis C and cirrhosis. N Engl J Med (2000) 3.74
Growth, adipose, brain, and skin alterations resulting from targeted disruption of the mouse peroxisome proliferator-activated receptor beta(delta). Mol Cell Biol (2000) 3.37
Carboxylation reactions and photosynthesis of carbon compounds in isolated mesophyll and bundle sheath cells of Digitaria sanguinalis (L.) Scop. Biochem Biophys Res Commun (1970) 3.05
Emerging invasive liver abscess caused by K1 serotype Klebsiella pneumoniae in Korea. J Infect (2006) 3.04
Binge eating is associated with right orbitofrontal-insular-striatal atrophy in frontotemporal dementia. Neurology (2007) 2.43
Rett syndrome and beyond: recurrent spontaneous and familial MECP2 mutations at CpG hotspots. Am J Hum Genet (1999) 2.42
Oncogenic human papillomavirus E6 proteins target the discs large tumour suppressor for proteasome-mediated degradation. Oncogene (1999) 2.25
The present and future disease burden of hepatitis C virus (HCV) infection with today's treatment paradigm. J Viral Hepat (2014) 2.23
Atherogenicity and carcinogenicity of high-arsenic artesian well water. Multiple risk factors and related malignant neoplasms of blackfoot disease. Arteriosclerosis (1988) 2.20
Interactions of the PDZ-protein MAGI-1 with adenovirus E4-ORF1 and high-risk papillomavirus E6 oncoproteins. Oncogene (2000) 2.20
Long-term (15 years) results after radical prostatectomy for clinically localized (stage T2c or lower) prostate cancer. J Urol (1994) 2.10
Glassy cell carcinoma of the uterine cervix. Cytologic features and expression of estrogen and progesterone receptors. Acta Cytol (2000) 2.05
A minimal role for selectins in the recruitment of leukocytes into the inflamed liver microvasculature. J Clin Invest (1997) 2.04
Public knowledge, attitudes and behavior on antibiotic use: a telephone survey in Hong Kong. Infection (2008) 2.02
Perfusion monitoring during radical perineal prostatectomy. Anesthesiology (1997) 2.01
Success of exchange reamed intramedullary nailing for femoral shaft nonunion or delayed union. J Orthop Trauma (2000) 1.95
Endoscopic ultrasound-guided versus conventional transmural drainage for pancreatic pseudocysts: a prospective randomized trial. Endoscopy (2009) 1.87
Endoscopic removal of biliary self-expandable metallic stents: a prospective study. Endoscopy (2006) 1.83
Eosinophilic meningitis caused by Angiostrongylus cantonensis: report of 17 cases. Am J Med (2001) 1.76
Radical prostatectomy for clinically localized prostate cancer: long-term results of 1,143 patients from a single institution. J Clin Oncol (1994) 1.75
Historical epidemiology of hepatitis C virus (HCV) in selected countries. J Viral Hepat (2014) 1.68
Treatment of acute colonic pseudoobstruction (Ogilvie's syndrome) with cisapride. Gastroenterology (1990) 1.67
Strategies to manage hepatitis C virus (HCV) disease burden. J Viral Hepat (2014) 1.67
Cardiac abnormalities in liver cirrhosis. West J Med (1989) 1.66
Migration and granulomatous reaction after periurethral injection of polytef (Teflon). JAMA (1984) 1.65
The definition and preoperative prediction of clinically insignificant prostate cancer. JAMA (1996) 1.65
Heterotransplantation of human cancers into nude mice: a model system for human cancer chemotherapy. Cancer (1978) 1.64
Universal decline in mortality in patients with advanced HIV-1 disease in various demographic subpopulations after the introduction of HAART in Hong Kong, from 1993 to 2002. HIV Med (2006) 1.61
Interferon for acute hepatitis C. Cochrane Database Syst Rev (2002) 1.52
Occlusive myocardial infarction: investigation of bis-gadolinium mesoporphyrins-enhanced T1-weighted MR imaging in a cat model. Radiology (2001) 1.47
Cirrhotic cardiomyopathy: getting to the heart of the matter. Hepatology (1996) 1.47
In vitro elution of antibiotic from antibiotic-impregnated biodegradable calcium alginate wound dressing. J Trauma (1999) 1.47
Associations of blood lead, dimercaptosuccinic acid-chelatable lead, and tibia lead with neurobehavioral test scores in South Korean lead workers. Am J Epidemiol (2001) 1.46
Prostate specific antigen values after radical retropubic prostatectomy for adenocarcinoma of the prostate: impact of adjuvant treatment (hormonal and radiation) J Urol (1991) 1.46
Central neural activation of hyperdynamic circulation in portal hypertensive rats depends on vagal afferent nerves. Gut (2008) 1.45
Exploring differences in response to treatment with peginterferon alpha 2a (40kD) and ribavirin in chronic hepatitis C between genotypes 2 and 3. J Viral Hepat (2008) 1.45
Initial experiences with a multidisciplinary approach to decreasing the length of hospital stay for patients undergoing unilateral mastectomy. Eur J Surg Oncol (2011) 1.45
Radiotherapy for isolated serum prostate specific antigen elevation after prostatectomy for prostate cancer. J Urol (2000) 1.45
Differences in clinical and laboratory diagnostic characteristics of penicilliosis marneffei in human immunodeficiency virus (HIV)- and non-HIV-infected patients. J Clin Microbiol (2001) 1.44
Comparison of six commercial techniques in the measurement of microalbuminuria in diabetic patients. Diabetes Care (1993) 1.42
Patterns of Medical Care: A Hospital's Outpatients. Am J Public Health Nations Health (1960) 1.42
Risk factors for recurrence of primary bile duct stones after endoscopic biliary sphincterotomy. Gastrointest Endosc (2001) 1.42
Extracorporeal circulation combined with hypothermia and hemodilution technique. Yonsei Med J (1963) 1.40
A prospective randomized comparison of epidural infusion of fentanyl and intravenous administration of morphine by patient-controlled analgesia after radical retropubic prostatectomy. Mayo Clin Proc (1992) 1.40
Human adenovirus early region 4 open reading frame 1 genes encode growth-transforming proteins that may be distantly related to dUTP pyrophosphatase enzymes. J Virol (1997) 1.39
Binary phase spatial modulation using photoinduced anisotropy in amorphous As(2)S(3) thin film. Appl Opt (1995) 1.39
Resistance to carbon tetrachloride-induced hepatotoxicity in mice which lack CYP2E1 expression. Toxicol Appl Pharmacol (1998) 1.39
Altered balance between matrix metalloproteinases and their inhibitors in experimental biliary fibrosis. Am J Pathol (1998) 1.38
Augmentative plate fixation for the management of femoral nonunion after intramedullary nailing. J Trauma (1997) 1.38
Topical corticosteroid therapy for cicatricial conjunctivitis associated with chronic graft-versus-host disease. Bone Marrow Transplant (2004) 1.37
Putaminal petechial haemorrhage as the cause of chorea: a neuroimaging study. J Neurol Neurosurg Psychiatry (1997) 1.36
A randomised phase II study of modified FOLFIRI.3 vs modified FOLFOX as second-line therapy in patients with gemcitabine-refractory advanced pancreatic cancer. Br J Cancer (2009) 1.36
Peroxisome proliferator-activated receptor-alpha regulates lipid homeostasis, but is not associated with obesity: studies with congenic mouse lines. J Biol Chem (2001) 1.34
Lymphocyte subpopulation reference ranges for monitoring human immunodeficiency virus-infected Chinese adults. Clin Diagn Lab Immunol (1996) 1.32
Choledochal cyst. A report of nine cases and review of the literature. Arch Surg (1969) 1.31
Mechanisms of steroid oxidation by microorganisms. XII. Metabolism of hexahydroindanpropionic acid derivatives. Biochemistry (1967) 1.30
Fatigue in patients with chronic hepatitis C. J Viral Hepat (2002) 1.30
A novel mimetic antigen eliciting protective antibody to Neisseria meningitidis. J Immunol (2001) 1.28
Mechanisms of steroid oxidation by microorganisms. 8. 3,4-Dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione, an intermediate in the microbiological degradation of ring A of androst-4-ene-3,17-dione. J Biol Chem (1966) 1.27
Phylogenetic relationships of Asian and European pig breeds determined by mitochondrial DNA D-loop sequence polymorphism. Anim Genet (2002) 1.27
Clinical characteristics of emphysematous pyelonephritis. J Microbiol Immunol Infect (2001) 1.26
Analysis of percutaneous transhepatic cholangioscopy-related complications and the risk factors for those complications. Endoscopy (2007) 1.25
Inflammatory pseudotumors of the lung. Surg Gynecol Obstet (1983) 1.25
The anti-tumor effect of Ganoderma lucidum is mediated by cytokines released from activated macrophages and T lymphocytes. Int J Cancer (1997) 1.24
Advantage of Fontana-Masson stain in capsule-deficient cryptococcal infection. Arch Pathol Lab Med (1987) 1.23
Peginterferon alfa-2a (40KD) plus ribavirin in chronic hepatitis C patients who failed previous interferon therapy. Gut (2006) 1.22
Inhibitory effects of [6]-gingerol, a major pungent principle of ginger, on phorbol ester-induced inflammation, epidermal ornithine decarboxylase activity and skin tumor promotion in ICR mice. Cancer Lett (1998) 1.21
Functional activity of anti-Neisserial surface protein A monoclonal antibodies against strains of Neisseria meningitidis serogroup B. Infect Immun (2001) 1.21
Aggressive angiomyxoma of the scrotum. Arch Androl (2002) 1.20
Comparison of the BACTEC MGIT 960 and BACTEC 460TB systems for detection of mycobacteria in clinical specimens. Ann Clin Lab Sci (2001) 1.20
The volume of prostate cancer in the biopsy specimen cannot reliably predict the quantity of cancer in the radical prostatectomy specimen on an individual basis. J Urol (1995) 1.19
Prognostic variables in parotid gland cancer. Arch Otolaryngol Head Neck Surg (1991) 1.19
Ectopic umbilical liver in conjunction with biliary atresia: uncommon association. J Pediatr Surg (1991) 1.19
In vivo assembly of rhodopsin from expressed polypeptide fragments. Proc Natl Acad Sci U S A (1995) 1.18
Link of the unique oncogenic properties of adenovirus type 9 E4-ORF1 to a select interaction with the candidate tumor suppressor protein ZO-2. EMBO J (2001) 1.18
Portal hypertensive gastropathy and gastric antral vascular ectasia (GAVE) syndrome. Gut (2001) 1.17
Fryns syndrome phenotype caused by chromosome microdeletions at 15q26.2 and 8p23.1. J Med Genet (2005) 1.16
Phylogenetic relationships of Cheju horses to other horse breeds as determined by mtDNA D-loop sequence polymorphism. Anim Genet (1999) 1.15
Sorafenib in patients with metastatic gastrointestinal stromal tumors who failed two or more prior tyrosine kinase inhibitors: a phase II study of Korean gastrointestinal stromal tumors study group. Invest New Drugs (2012) 1.15
Congophilic angiopathy and cerebral hemorrhage. Arch Pathol Lab Med (1978) 1.15
A new classification of the retinoschises. Retina (1995) 1.15
Role of heme oxygenase-carbon monoxide pathway in pathogenesis of cirrhotic cardiomyopathy in the rat. Am J Physiol Gastrointest Liver Physiol (2001) 1.15
Oral drug of choice in carpal tunnel syndrome. Neurology (1998) 1.14
Purification of human blood eosinophils by negative selection using immunomagnetic beads. J Immunol Methods (1989) 1.14
Human placental 3 beta-hydroxy-5-ene-steroid dehydrogenase and steroid 5----4-ene-isomerase: purification from mitochondria and kinetic profiles, biophysical characterization of the purified mitochondrial and microsomal enzymes. J Steroid Biochem (1989) 1.14
MECP2 truncating mutations cause histone H4 hyperacetylation in Rett syndrome. Hum Mol Genet (2001) 1.14
Basaloid squamous carcinoma of the oesophagus: a distinct neoplasm with multipotential differentiation. Histopathology (2000) 1.14
Goblet cell carcinoids of the appendix. Surg Gynecol Obstet (1988) 1.13
Cirrhotic cardiomyopathy and liver transplantation. Liver Transpl (2000) 1.13
Molecular cloning and localization of human syntaxin 16, a member of the syntaxin family of SNARE proteins. Biochem Biophys Res Commun (1998) 1.13
Editorial: Anti-viral therapy for prevention of perinatal HBV transmission--extending therapy beyond birth and the risk of post-partum flare. Aliment Pharmacol Ther (2014) 1.12