Published in Breast Cancer Res on September 14, 2005
Review of the Gene-Environment Interaction Literature in Cancer: What Do We Know? Genet Epidemiol (2016) 0.79
CYP17 and breast cancer: no overall effect, but what about interactions? Breast Cancer Res (2005) 0.77
CYP17 MspA1 polymorphism and age at menarche: a meta-analysis. Dis Markers (2008) 0.75
Polymorphisms associated with circulating sex hormone levels in postmenopausal women. J Natl Cancer Inst (2004) 3.53
Analysis of changes in DNA sequence copy number by comparative genomic hybridization in archival paraffin-embedded tumor samples. Am J Pathol (1994) 2.86
Epidemiology of endocrine-related risk factors for breast cancer. J Mammary Gland Biol Neoplasia (2002) 2.57
Nutrition, hormones, and breast cancer: is insulin the missing link? Cancer Causes Control (1996) 2.55
Robust and accurate single nucleotide polymorphism genotyping by dynamic allele-specific hybridization (DASH): design criteria and assay validation. Genome Res (2001) 2.19
Breast-cancer risk following long-term oestrogen- and oestrogen-progestin-replacement therapy. Int J Cancer (1999) 1.98
Body size in different periods of life and breast cancer risk in post-menopausal women. Int J Cancer (1998) 1.86
Polycystic ovaries and premature male pattern baldness are associated with one allele of the steroid metabolism gene CYP17. Hum Mol Genet (1994) 1.58
The CYP17 MspA1 polymorphism and breast cancer risk: a meta-analysis. Mutagenesis (2002) 1.58
Breast cancer risk associated with genotype polymorphism of the estrogen-metabolizing genes CYP17, CYP1A1, and COMT: a multigenic study on cancer susceptibility. Cancer Res (1999) 1.47
A polymorphism in the CYP17 gene increases the risk of breast cancer. Cancer Res (1997) 1.46
Cloning and sequence of the human gene for P450c17 (steroid 17 alpha-hydroxylase/17,20 lyase): similarity with the gene for P450c21. DNA (1987) 1.44
Cytochrome P450c17alpha gene (CYP17) polymorphism is associated with serum estrogen and progesterone concentrations. Cancer Res (1998) 1.38
Oestrogen receptor alpha gene haplotype and postmenopausal breast cancer risk: a case control study. Breast Cancer Res (2004) 1.36
Association of CYP17, CYP19, CYP1B1, and COMT polymorphisms with serum and urinary sex hormone concentrations in postmenopausal women. Cancer Epidemiol Biomarkers Prev (2004) 1.35
Relationship between serum hormone concentrations, reproductive history, alcohol consumption and genetic polymorphisms in pre-menopausal women. Int J Cancer (2002) 1.27
The relationship between a polymorphism in CYP17 with plasma hormone levels and breast cancer. Cancer Res (1999) 1.25
Multiplex, fluorescent, solid-phase minisequencing for efficient screening of DNA sequence variation. Clin Chem (1996) 1.20
CYP17 gene polymorphisms: prevalence and associations with hormone levels and related factors. a HuGE review. Am J Epidemiol (2004) 1.16
CYP17 and breast cancer risk: the polymorphism in the 5' flanking area of the gene does not influence binding to Sp-1. Cancer Res (1999) 1.14
The role of reproductive factors and use of oral contraceptives in the aetiology of breast cancer in women aged 50 to 74 years. Int J Cancer (1999) 1.12
No association between a polymorphism in the steroid metabolism gene CYP17 and risk of breast cancer. Br J Cancer (1998) 1.09
C21 steroid side chain cleavage enzyme from porcine adrenal microsomes. Purification and characterization of the 17 alpha-hydroxylase/C17,20-lyase cytochrome P-450. J Biol Chem (1984) 1.06
Association of family history and other risk factors with breast cancer risk (Sweden). Cancer Causes Control (1998) 1.03
HSD17B1 and CYP17 polymorphisms and breast cancer risk among Chinese women in Singapore. Int J Cancer (2003) 1.02
Breast cancer risk and lifetime leisure-time and occupational physical activity (Sweden). Cancer Causes Control (2000) 1.01
Brassica vegetables and breast cancer risk. JAMA (2001) 1.01
Association between CYP17 polymorphisms and the development of breast cancer. Cancer Epidemiol Biomarkers Prev (1998) 1.01
Steroid metabolism gene CYP17 polymorphism and the development of breast cancer. Cancer Epidemiol Biomarkers Prev (2000) 1.00
Estrogen-metabolizing gene polymorphisms in the assessment of breast carcinoma risk and fibroadenoma risk in Caucasian women. Cancer (2004) 0.99
CYP17 genotype and breast cancer risk. Cancer Epidemiol Biomarkers Prev (1998) 0.99
A polymorphism in CYP17 and endometrial cancer risk. Cancer Res (2001) 0.98
Cytochrome P450 1B1 gene polymorphisms and postmenopausal breast cancer risk. Carcinogenesis (2003) 0.97
Catechol-O-methyltransferase gene polymorphism and post-menopausal breast cancer risk. Carcinogenesis (2003) 0.96
Estrogen-metabolizing gene polymorphisms, but not estrogen receptor-alpha gene polymorphisms, are associated with the onset of menarche in healthy postmenopausal Japanese women. J Clin Endocrinol Metab (2003) 0.94
CYP gene polymorphisms and early menarche. Mol Genet Metab (2001) 0.93
Cytochrome P450c17alpha gene (CYP17) polymorphism predicts use of hormone replacement therapy. Cancer Res (1999) 0.92
Overexpression of theca-cell messenger RNA in polycystic ovary syndrome does not correlate with polymorphisms in the cholesterol side-chain cleavage and 17alpha-hydroxylase/C(17-20) lyase promoters. Fertil Steril (2002) 0.91
Variants in estrogen-biosynthesis genes CYP17 and CYP19 and breast cancer risk: a family-based genetic association study. Breast Cancer Res (2004) 0.90
Genetic polymorphism in CYP17 and breast cancer risk in Japanese women. Eur J Cancer (2000) 0.89
CYP17 and SULT1A1 gene polymorphisms in Indian breast cancer. Breast Cancer (2004) 0.86
No association of the 5' promoter region polymorphism of CYP17 with breast cancer risk in Japan. Jpn J Cancer Res (2000) 0.86
CYP17 promoter polymorphism and breast cancer risk in males and females in relation to BRCA2 status. Br J Cancer (2003) 0.85
Association between the T27C polymorphism in the cytochrome P450 c17alpha (CYP17) gene and risk factors for breast cancer. Breast Cancer Res Treat (2004) 0.85
CYP17 genetic polymorphism, breast cancer, and breast cancer risk factors. Breast Cancer Res (2003) 0.84
Risk of endometrial cancer and estrogen replacement therapy history by CYP17 genotype. Cancer Res (2001) 0.82
CYP17 genotype and ovarian cancer: a null case-control study. Cancer Epidemiol Biomarkers Prev (2001) 0.81
CYP17 5'-UTR MspA1 polymorphism and the risk of premenopausal breast cancer in a German population-based case-control study. Breast Cancer Res (2005) 0.80
Concerning the CYP17 MspA1 polymorphism and breast cancer risk: a meta-analysis. Mutagenesis (2002) 0.79
CYP17 genetic polymorphism, breast cancer, and breast cancer risk factors: Australian Breast Cancer Family Study. Breast Cancer Res (2005) 0.79
Genome-wide association study identifies novel breast cancer susceptibility loci. Nature (2007) 29.23
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet (2010) 23.08
Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature (2010) 20.01
Risk of ischemic heart disease in women after radiotherapy for breast cancer. N Engl J Med (2013) 13.92
An expression signature for p53 status in human breast cancer predicts mutation status, transcriptional effects, and patient survival. Proc Natl Acad Sci U S A (2005) 13.54
Body-mass index and mortality among 1.46 million white adults. N Engl J Med (2010) 13.34
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. Nature (2011) 13.23
Gene expression profiling spares early breast cancer patients from adjuvant therapy: derived and validated in two population-based cohorts. Breast Cancer Res (2005) 8.73
Large-scale genotyping identifies 41 new loci associated with breast cancer risk. Nat Genet (2013) 8.24
Genetic reclassification of histologic grade delineates new clinical subtypes of breast cancer. Cancer Res (2006) 8.08
A common coding variant in CASP8 is associated with breast cancer risk. Nat Genet (2007) 7.35
Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2. Nat Genet (2009) 7.30
Heterogeneity of breast cancer associations with five susceptibility loci by clinical and pathological characteristics. PLoS Genet (2008) 6.22
Mobile phone use and the risk of acoustic neuroma. Epidemiology (2004) 6.04
The new Swedish Prescribed Drug Register--opportunities for pharmacoepidemiological research and experience from the first six months. Pharmacoepidemiol Drug Saf (2007) 5.28
Progress in tuberculosis control and the evolving public-health system in China. Lancet (2007) 4.86
GWAS of 126,559 individuals identifies genetic variants associated with educational attainment. Science (2013) 4.71
Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis. Nat Genet (2013) 4.62
Toward more responsive and effective intervention systems for alcohol-related problems. Addiction (2002) 4.59
Associations of breast cancer risk factors with tumor subtypes: a pooled analysis from the Breast Cancer Association Consortium studies. J Natl Cancer Inst (2010) 4.54
Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer. Nat Genet (2013) 4.35
Smokeless tobacco use and risk of cancer of the pancreas and other organs. Int J Cancer (2005) 4.24
Low carbohydrate-high protein diet and incidence of cardiovascular diseases in Swedish women: prospective cohort study. BMJ (2012) 4.05
Health Effects of Overweight and Obesity in 195 Countries over 25 Years. N Engl J Med (2017) 3.90
Origins and genetic legacy of Neolithic farmers and hunter-gatherers in Europe. Science (2012) 3.82
Genome-wide association studies identify four ER negative-specific breast cancer risk loci. Nat Genet (2013) 3.81
Long-term mobile phone use and brain tumor risk. Am J Epidemiol (2005) 3.80
Second cancers among 40,576 testicular cancer patients: focus on long-term survivors. J Natl Cancer Inst (2005) 3.73
Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci. Nat Genet (2011) 3.46
GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer. Nat Genet (2013) 3.42
Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies. Nat Genet (2010) 3.37
A common variant at the TERT-CLPTM1L locus is associated with estrogen receptor-negative breast cancer. Nat Genet (2011) 3.37
A prospective study of pigmentation, sun exposure, and risk of cutaneous malignant melanoma in women. J Natl Cancer Inst (2003) 3.29
Niemann-Pick C1 Like 1 (NPC1L1) is the intestinal phytosterol and cholesterol transporter and a key modulator of whole-body cholesterol homeostasis. J Biol Chem (2004) 3.27
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Nat Genet (2013) 3.25
Combined analysis from eleven linkage studies of bipolar disorder provides strong evidence of susceptibility loci on chromosomes 6q and 8q. Am J Hum Genet (2005) 3.24
Who is responsible for the public's health? The role of the alcohol industry in the WHO global strategy to reduce the harmful use of alcohol. Addiction (2013) 3.24
Genome-wide association analysis identifies three new breast cancer susceptibility loci. Nat Genet (2012) 3.20
Cancer survival in Africa, Asia, and Central America: a population-based study. Lancet Oncol (2009) 3.14
A common novel CYP2C19 gene variant causes ultrarapid drug metabolism relevant for the drug response to proton pump inhibitors and antidepressants. Clin Pharmacol Ther (2006) 3.09
Inflammatory and metabolic biomarkers and risk of liver and biliary tract cancer. Hepatology (2014) 3.06
2009 influenza A(H1N1) seroconversion rates and risk factors among distinct adult cohorts in Singapore. JAMA (2010) 3.05
Genome scan meta-analysis of schizophrenia and bipolar disorder, part III: Bipolar disorder. Am J Hum Genet (2003) 3.02
Cancer as a risk factor for long-term cognitive deficits and dementia. J Natl Cancer Inst (2005) 3.02
Dietary long-chain n-3 fatty acids for the prevention of cancer: a review of potential mechanisms. Am J Clin Nutr (2004) 3.01
Pharmacogenomics and individualized drug therapy. Annu Rev Med (2006) 2.95
Electronic support groups for breast carcinoma: a clinical trial of effectiveness. Cancer (2003) 2.93
Risk of estrogen receptor-positive and -negative breast cancer and single-nucleotide polymorphism 2q35-rs13387042. J Natl Cancer Inst (2009) 2.88
Evaluation of human papillomavirus antibodies and risk of subsequent head and neck cancer. J Clin Oncol (2013) 2.87
Feasibility of using web-based questionnaires in large population-based epidemiological studies. Eur J Epidemiol (2006) 2.86
Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits. PLoS Genet (2013) 2.83
FTO genotype is associated with phenotypic variability of body mass index. Nature (2012) 2.77
Risk of ovarian cancer in breast-cancer patients with a family history of breast or ovarian cancer: a population-based cohort study. Lancet (2002) 2.72
Low penetrance breast cancer susceptibility loci are associated with specific breast tumor subtypes: findings from the Breast Cancer Association Consortium. Hum Mol Genet (2011) 2.72
Second cancers among 104,760 survivors of cervical cancer: evaluation of long-term risk. J Natl Cancer Inst (2007) 2.70
Intrinsic molecular signature of breast cancer in a population-based cohort of 412 patients. Breast Cancer Res (2006) 2.69
Meta-analysis of naltrexone and acamprosate for treating alcohol use disorders: when are these medications most helpful? Addiction (2012) 2.64
A genome-wide association study of nasopharyngeal carcinoma identifies three new susceptibility loci. Nat Genet (2010) 2.62
A randomized controlled trial of an internet-based intervention for alcohol abusers. Addiction (2009) 2.61
Occupation and cancer - follow-up of 15 million people in five Nordic countries. Acta Oncol (2009) 2.59
Social networks as mediators of the effect of Alcoholics Anonymous. Addiction (2002) 2.52
A genomewide screen of 345 families for autism-susceptibility loci. Am J Hum Genet (2003) 2.51
Clinically significant prognostic factors for differentiated thyroid carcinoma: a population-based, nested case-control study. Cancer (2006) 2.46
A meta-analysis of genome-wide association studies of breast cancer identifies two novel susceptibility loci at 6q14 and 20q11. Hum Mol Genet (2012) 2.45
Leisure time physical activity of moderate to vigorous intensity and mortality: a large pooled cohort analysis. PLoS Med (2012) 2.45
Systematic review and meta-analysis of circulatory disease from exposure to low-level ionizing radiation and estimates of potential population mortality risks. Environ Health Perspect (2012) 2.42
Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk. PLoS Genet (2013) 2.39
Genome-wide association study of follicular lymphoma identifies a risk locus at 6p21.32. Nat Genet (2010) 2.37
Genetic structure of the Han Chinese population revealed by genome-wide SNP variation. Am J Hum Genet (2009) 2.33
Evidence for a language quantitative trait locus on chromosome 7q in multiplex autism families. Am J Hum Genet (2001) 2.29
The pursuit of genome-wide association studies: where are we now? J Hum Genet (2010) 2.28