Published in Mol Pharmacol on November 10, 2005
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P2X4 receptors mediate PGE2 release by tissue-resident macrophages and initiate inflammatory pain. EMBO J (2010) 1.31
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Ivermectin antagonizes ethanol inhibition in purinergic P2X4 receptors. J Pharmacol Exp Ther (2010) 1.01
Functional evidence for the expression of P2X1, P2X4 and P2X7 receptors in human lung mast cells. Br J Pharmacol (2009) 0.99
ATP receptors gate microglia signaling in neuropathic pain. Exp Neurol (2011) 0.96
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P2X4 purinoceptor signaling in chronic pain. Purinergic Signal (2012) 0.91
Two open states of P2X receptor channels. Front Cell Neurosci (2013) 0.91
Cross-talk between P2X4 and gamma-aminobutyric acid, type A receptors determines synaptic efficacy at a central synapse. J Biol Chem (2011) 0.90
Interaction of P2 purinergic receptors with cellular macromolecules. Naunyn Schmiedebergs Arch Pharmacol (2007) 0.86
Roles of conserved ectodomain cysteines of the rat P2X4 purinoreceptor in agonist binding and channel gating. Physiol Res (2010) 0.86
Ivermectin-dependent release of IL-1beta in response to ATP by peritoneal macrophages from P2X(7)-KO mice. Purinergic Signal (2010) 0.85
Nicotinic acetylcholine receptor alpha7 subunits with a C2 cytoplasmic loop yellow fluorescent protein insertion form functional receptors. Acta Pharmacol Sin (2009) 0.85
Contribution of P2X4 receptors to ethanol intake in male C57BL/6 mice. Neurochem Res (2014) 0.85
Allosteric modulation of purine and pyrimidine receptors. Adv Pharmacol (2011) 0.84
Allosteric regulation of the P2X4 receptor channel pore dilation. Pflugers Arch (2014) 0.83
Agonist-dependent endocytosis of γ-aminobutyric acid type A (GABAA) receptors revealed by a γ2(R43Q) epilepsy mutation. J Biol Chem (2013) 0.82
Imaging P2X4 receptor subcellular distribution, trafficking, and regulation using P2X4-pHluorin. J Gen Physiol (2014) 0.82
Distinct contributions by ionotropic purinoceptor subtypes to ATP-evoked calcium signals in mouse parotid acinar cells. J Physiol (2012) 0.81
Identification of functionally important residues of the rat P2X4 receptor by alanine scanning mutagenesis of the dorsal fin and left flipper domains. PLoS One (2014) 0.81
Shear stress modulates endothelial KLF2 through activation of P2X4. Purinergic Signal (2015) 0.81
Protein kinase A regulation of P2X(4) receptors: requirement for a specific motif in the C-terminus. Biochim Biophys Acta (2009) 0.79
Rab5 regulates internalisation of P2X4 receptors and potentiation by ivermectin. Purinergic Signal (2012) 0.79
Basolateral P2X₄channels stimulate ENaC activity in Xenopus cortical collecting duct A6 cells. Am J Physiol Renal Physiol (2014) 0.78
Morphine enhances IL-1β release through toll-like receptor 4-mediated endocytic pathway in microglia. Purinergic Signal (2016) 0.77
Differential membrane redistribution of P2X receptor isoforms in response to osmotic and hyperglycemic stress in the rat lens. Histochem Cell Biol (2009) 0.77
P2X-mediated AMPA receptor internalization and synaptic depression is controlled by two CaMKII phosphorylation sites on GluA1 in hippocampal neurons. Sci Rep (2016) 0.75
Deciphering the regulation of P2X4 receptor channel gating by ivermectin using Markov models. PLoS Comput Biol (2017) 0.75
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A functional P2X7 splice variant with an alternative transmembrane domain 1 escapes gene inactivation in P2X7 knock-out mice. J Biol Chem (2009) 1.29
Biochemical and functional evidence for heteromeric assembly of P2X1 and P2X4 subunits. J Neurochem (2005) 1.22
Evidence for inhibition mediated by coassembly of GABAA and GABAC receptor subunits in native central neurons. J Neurosci (2004) 1.19
Fluorescence measurements reveal stoichiometry of K+ channels formed by modulatory and delayed rectifier alpha-subunits. Proc Natl Acad Sci U S A (2005) 1.11
Development of cell type-specific connectivity patterns of converging excitatory axons in the retina. Neuron (2011) 1.07
D5 (not D1) dopamine receptors potentiate burst-firing in neurons of the subthalamic nucleus by modulating an L-type calcium conductance. J Neurosci (2003) 1.06
Pharmacological properties of GABAA receptors in rat hypothalamic neurons expressing the epsilon-subunit. J Neurosci (2005) 1.04
Subunit-specific coupling between gamma-aminobutyric acid type A and P2X2 receptor channels. J Biol Chem (2004) 1.03
Brain-endocrine interactions: a microvascular route in the mediobasal hypothalamus. Endocrinology (2009) 1.03
Phosphoinositides regulate P2X4 ATP-gated channels through direct interactions. J Neurosci (2008) 1.03
A gamma 2(R43Q) mutation, linked to epilepsy in humans, alters GABAA receptor assembly and modifies subunit composition on the cell surface. J Biol Chem (2006) 1.02
PSD-95 expression controls L-DOPA dyskinesia through dopamine D1 receptor trafficking. J Clin Invest (2012) 0.98
An intracellular motif of P2X(3) receptors is required for functional cross-talk with GABA(A) receptors in nociceptive DRG neurons. J Neurochem (2007) 0.97
GABAA receptor epsilon subunit expression in identified peptidergic neurons of the rat hypothalamus. Brain Res (2003) 0.97
Fe65 interacts with P2X2 subunits at excitatory synapses and modulates receptor function. J Biol Chem (2005) 0.93
Cross-talk and co-trafficking between rho1/GABA receptors and ATP-gated channels. J Biol Chem (2003) 0.91
P2X4 receptor channels form large noncytolytic pores in resting and activated microglia. Glia (2012) 0.90
Cross-talk between P2X4 and gamma-aminobutyric acid, type A receptors determines synaptic efficacy at a central synapse. J Biol Chem (2011) 0.90
Enriching the environment of alphaCaMKIIT286A mutant mice reveals that LTD occurs in memory processing but must be subsequently reversed by LTP. Learn Mem (2007) 0.86
P2X4 receptor is a glycosylated cardiac receptor mediating a positive inotropic response to ATP. J Biol Chem (2002) 0.85
Spatial relationships between GABAergic and glutamatergic synapses on the dendrites of distinct types of mouse retinal ganglion cells across development. PLoS One (2013) 0.85
Agonist-dependent endocytosis of γ-aminobutyric acid type A (GABAA) receptors revealed by a γ2(R43Q) epilepsy mutation. J Biol Chem (2013) 0.82
Gene expression profiling of the rat superior olivary complex using serial analysis of gene expression. Eur J Neurosci (2004) 0.80
Selective potentiation of homomeric P2X2 ionotropic ATP receptors by a fast non-genomic action of progesterone. Neuropharmacology (2009) 0.80
Impact of chronic subthalamic high-frequency stimulation on metabolic basal ganglia activity: a 2-deoxyglucose uptake and cytochrome oxidase mRNA study in a macaque model of Parkinson's disease. Eur J Neurosci (2007) 0.79
Ectodermal P2X receptor function plays a pivotal role in craniofacial development of the zebrafish. Purinergic Signal (2009) 0.79
Selective knock-down of P2X7 ATP receptor function by dominant-negative subunits. Mol Pharmacol (2004) 0.78
Interplay between ionotropic receptors modulates inhibitory synaptic strength. Commun Integr Biol (2011) 0.75