Local and systemic drug competition in drug-eluting stent tissue deposition properties.

PubWeight™: 0.85‹?›

🔗 View Article (PMID 16289420)

Published in J Control Release on November 11, 2005

Authors

Andrew D Levin1, Michael Jonas, Chao-Wei Hwang, Elazer R Edelman

Author Affiliations

1: Harvard-MIT Division of Health Sciences and Technology, Massachusetts, Institute of Technology, Cambridge, 02139, USA. adlevin@mit.edu

Articles by these authors

Efficacy of a device to narrow the coronary sinus in refractory angina. N Engl J Med (2015) 5.36

Role of endothelial shear stress in the natural history of coronary atherosclerosis and vascular remodeling: molecular, cellular, and vascular behavior. J Am Coll Cardiol (2007) 4.62

Stent thrombogenicity early in high-risk interventional settings is driven by stent design and deployment and protected by polymer-drug coatings. Circulation (2011) 3.16

Kruppel-like factor 4 regulates endothelial inflammation. J Biol Chem (2007) 3.06

Luminal flow patterns dictate arterial drug deposition in stent-based delivery. J Control Release (2008) 1.90

Tissue engineering therapy for cardiovascular disease. Circ Res (2003) 1.87

Vacuum-assisted closure: microdeformations of wounds and cell proliferation. Plast Reconstr Surg (2004) 1.81

Prediction of the localization of high-risk coronary atherosclerotic plaques on the basis of low endothelial shear stress: an intravascular ultrasound and histopathology natural history study. Circulation (2008) 1.74

Increased thrombosis after arterial injury in human C-reactive protein-transgenic mice. Circulation (2003) 1.72

Uremic serum and solutes increase post-vascular interventional thrombotic risk through altered stability of smooth muscle cell tissue factor. Circulation (2012) 1.70

Heparanase alters arterial structure, mechanics, and repair following endovascular stenting in mice. Circ Res (2008) 1.64

Stromal endothelial cells directly influence cancer progression. Sci Transl Med (2011) 1.46

In vivo and in vitro tracking of erosion in biodegradable materials using non-invasive fluorescence imaging. Nat Mater (2011) 1.46

Drug-eluting stents in preclinical studies: recommended evaluation from a consensus group. Circulation (2002) 1.45

Ultrasound-guided percutaneous delivery of tissue-engineered endothelial cells to the adventitia of stented arteries controls the response to vascular injury in a porcine model. J Vasc Surg (2012) 1.42

Specific binding to intracellular proteins determines arterial transport properties for rapamycin and paclitaxel. Proc Natl Acad Sci U S A (2004) 1.32

Vascular neointimal formation and signaling pathway activation in response to stent injury in insulin-resistant and diabetic animals. Circ Res (2005) 1.32

Aldehyde-amine chemistry enables modulated biosealants with tissue-specific adhesion. Adv Mater (2009) 1.31

Intravascular drug release kinetics dictate arterial drug deposition, retention, and distribution. J Control Release (2007) 1.29

Enhanced T-helper-1 lymphocyte activation patterns in acute coronary syndromes. J Am Coll Cardiol (2005) 1.27

Strut position, blood flow, and drug deposition: implications for single and overlapping drug-eluting stents. Circulation (2005) 1.26

Natural history of experimental coronary atherosclerosis and vascular remodeling in relation to endothelial shear stress: a serial, in vivo intravascular ultrasound study. Circulation (2010) 1.19

Vascular bed origin dictates flow pattern regulation of endothelial adhesion molecule expression. Am J Physiol Heart Circ Physiol (2007) 1.18

Characterization of star adhesive sealants based on PEG/dextran hydrogels. Macromol Biosci (2009) 1.18

Luminal flow amplifies stent-based drug deposition in arterial bifurcations. PLoS One (2009) 1.17

Perivascular endothelial implants inhibit intimal hyperplasia in a model of arteriovenous fistulae: a safety and efficacy study in the pig. J Vasc Res (2003) 1.12

Arterial ultrastructure influences transport of locally delivered drugs. Circ Res (2002) 1.11

Endothelial cells provide feedback control for vascular remodeling through a mechanosensitive autocrine TGF-beta signaling pathway. Circ Res (2008) 1.11

Augmented expression and activity of extracellular matrix-degrading enzymes in regions of low endothelial shear stress colocalize with coronary atheromata with thin fibrous caps in pigs. Circulation (2011) 1.11

Systemic inflammation induced by lipopolysaccharide increases neointimal formation after balloon and stent injury in rabbits. Circulation (2002) 1.11

Current smoking, smoking cessation, and the risk of sudden cardiac death in patients with coronary artery disease. Arch Intern Med (2003) 1.07

Rapamycin for cardiac transplant rejection and vasculopathy: one stone, two birds? Circulation (2003) 1.06

Regulatory T cells and IL-10 levels are reduced in patients with vulnerable coronary plaques. Atherosclerosis (2012) 1.06

Glucose modulates basement membrane fibroblast growth factor-2 via alterations in endothelial cell permeability. J Biol Chem (2007) 1.05

Cardiology is flow. Circulation (2006) 1.04

Adventitial endothelial implants reduce matrix metalloproteinase-2 expression and increase luminal diameter in porcine arteriovenous grafts. J Vasc Surg (2007) 1.04

Liposomal alendronate inhibits systemic innate immunity and reduces in-stent neointimal hyperplasia in rabbits. Circulation (2003) 1.03

Impact of transport and drug properties on the local pharmacology of drug-eluting stents. Int J Cardiovasc Intervent (2003) 1.02

Dynamic flow alterations dictate leukocyte adhesion and response to endovascular interventions. J Clin Invest (2004) 1.02

Matrix embedding alters the immune response against endothelial cells in vitro and in vivo. Circulation (2005) 1.02

Lesion complexity determines arterial drug distribution after local drug delivery. J Control Release (2009) 1.00

Smooth muscle cells orchestrate the endothelial cell response to flow and injury. Circulation (2010) 1.00

Oral acetylcysteine as an adjunct to saline hydration for the prevention of contrast-induced nephropathy following coronary angiography. A randomized controlled trial and review of the current literature. Eur Heart J (2004) 1.00

The role of low endothelial shear stress in the conversion of atherosclerotic lesions from stable to unstable plaque. Curr Opin Cardiol (2009) 0.98

Dysfunctional endothelial cells directly stimulate cancer inflammation and metastasis. Int J Cancer (2013) 0.98

Thrombosis modulates arterial drug distribution for drug-eluting stents. Circulation (2005) 0.98

Viscoelastic adhesive mechanics of aldehyde-mediated soft tissue sealants. Biomaterials (2008) 0.97

Natural tissue microenvironmental conditions modulate adhesive material performance. Langmuir (2012) 0.97

Regulation of endothelial cell proliferation by primary monocytes. Arterioscler Thromb Vasc Biol (2007) 0.96

Tissue-engineered endothelial and epithelial implants differentially and synergistically regulate airway repair. Proc Natl Acad Sci U S A (2008) 0.96

Thrombus causes fluctuations in arterial drug delivery from intravascular stents. J Control Release (2008) 0.95

Matrix adherence of endothelial cells attenuates immune reactivity: induction of hyporesponsiveness in allo- and xenogeneic models. FASEB J (2007) 0.94

Syndecan-4 proteoliposomes enhance fibroblast growth factor-2 (FGF-2)-induced proliferation, migration, and neovascularization of ischemic muscle. Proc Natl Acad Sci U S A (2012) 0.94

Role of fluid dynamics and inflammation in intracranial aneurysm formation. Circulation (2014) 0.93

Attenuation of inflammation and expansive remodeling by Valsartan alone or in combination with Simvastatin in high-risk coronary atherosclerotic plaques. Atherosclerosis (2008) 0.93

Preclinical evaluation of drug-eluting stents for peripheral applications: recommendations from an expert consensus group. Circulation (2004) 0.93

Subclavian coronary steal syndrome: an obligatory common fate between subclavian artery, internal mammary graft and coronary circulation. Cardiology (2002) 0.92

Cells in fluidic environments are sensitive to flow frequency. J Cell Physiol (2005) 0.92

Endothelial immunogenicity--a matter of matrix microarchitecture. Thromb Haemost (2007) 0.91

Endothelial cell-matrix interactions determine maturation of dendritic cells. Eur J Immunol (2007) 0.90

The evolution of endothelial regulatory paradigms in cancer biology and vascular repair. Cancer Res (2011) 0.90

Revascularization for coronary artery disease in diabetes mellitus: angioplasty, stents and coronary artery bypass grafting. Rev Endocr Metab Disord (2010) 0.90

Transgenic expression of human C-reactive protein suppresses endothelial nitric oxide synthase expression and bioactivity after vascular injury. Am J Physiol Heart Circ Physiol (2007) 0.90

Quasi-steady-state kinetics at enzyme and substrate concentrations in excess of the Michaelis-Menten constant. J Theor Biol (2006) 0.90

Cell-matrix contact prevents recognition and damage of endothelial cells in states of heightened immunity. Circulation (2006) 0.90

Leukocyte recruitment and expression of chemokines following different forms of vascular injury. Vasc Med (2003) 0.90

Regulation of heparanase expression in coronary artery disease in diabetic, hyperlipidemic swine. Atherosclerosis (2010) 0.89

The effect of three-dimensional matrix-embedding of endothelial cells on the humoral and cellular immune response. Semin Immunol (2008) 0.89

Analysis of compartmental models of ligand-induced endocytosis. J Theor Biol (2004) 0.89

Endosomal receptor kinetics determine the stability of intracellular growth factor signalling complexes. Biochem J (2007) 0.88

Embolic protection with filtering or occlusion balloons during saphenous vein graft stenting retrieves identical volumes and sizes of particulate debris. Circulation (2004) 0.87

The PROXIMAL trial: proximal protection during saphenous vein graft intervention using the Proxis Embolic Protection System: a randomized, prospective, multicenter clinical trial. J Am Coll Cardiol (2007) 0.87

Anti-atherosclerotic therapy based on botanicals. Recent Pat Cardiovasc Drug Discov (2013) 0.87

A structural model that explains the effects of hyperglycemia on collagenolysis. Biophys J (2003) 0.87

Low background, pulsatile, in vitro flow circuit for modeling coronary implant thrombosis. J Biomech Eng (2002) 0.87

Augmentation of postswelling surgical sealant potential of adhesive hydrogels. J Biomed Mater Res A (2010) 0.86

Phosphorylation-induced conformational changes in a mitogen-activated protein kinase substrate. Implications for tyrosine hydroxylase activation. J Biol Chem (2002) 0.86

Effect of pre-adsorbed proteins on attachment, proliferation, and function of endothelial cells. J Cell Physiol (2002) 0.86

Proangiogenic stimulation of bone marrow endothelium engages mTOR and is inhibited by simultaneous blockade of mTOR and NF-kappaB. Blood (2005) 0.86

Acute rejection in vascularized composite allotransplantation. Curr Opin Organ Transplant (2014) 0.86

Heparanase regulates thrombosis in vascular injury and stent-induced flow disturbance. J Am Coll Cardiol (2012) 0.86

Mechanisms of tissue uptake and retention in zotarolimus-coated balloon therapy. Circulation (2013) 0.85

The effect of substrate modulus on the growth and function of matrix-embedded endothelial cells. Biomaterials (2012) 0.85

Pushing drug-eluting stents into uncharted territory: simpler than you think--more complex than you imagine. Circulation (2006) 0.85

Thin-capped atheromata with reduced collagen content in pigs develop in coronary arterial regions exposed to persistently low endothelial shear stress. Arterioscler Thromb Vasc Biol (2013) 0.85

Impact of flow pulsatility on arterial drug distribution in stent-based therapy. J Control Release (2013) 0.85

Tubular bridges for bronchial epithelial cell migration and communication. PLoS One (2010) 0.85

Environmental influences on endovascular stent platelet reactivity: an in vitro comparison of stainless steel and gold surfaces. J Biomed Mater Res A (2004) 0.85

Primary monocytes regulate endothelial cell survival through secretion of angiopoietin-1 and activation of endothelial Tie2. Arterioscler Thromb Vasc Biol (2011) 0.84