Published in Nat Methods on December 01, 2005
Exploiting position effects and the gypsy retrovirus insulator to engineer precisely expressed transgenes. Nat Genet (2008) 5.50
Comparative and developmental study of the immune system in Xenopus. Dev Dyn (2009) 1.68
Amphibian metamorphosis. Dev Biol (2007) 1.43
A diversity of serine phage integrases mediate site-specific recombination in mammalian cells. Mol Genet Genomics (2006) 1.26
A method for producing transgenic cells using a multi-integrase system on a human artificial chromosome vector. PLoS One (2011) 1.26
A motif in the C-terminal domain of phiC31 integrase controls the directionality of recombination. Nucleic Acids Res (2008) 1.25
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Mutational derivatives of PhiC31 integrase with increased efficiency and specificity. Mol Ther (2008) 1.23
Xenopus as a model system for vertebrate heart development. Semin Cell Dev Biol (2006) 1.18
Decoding development in Xenopus tropicalis. Genesis (2007) 1.07
Transgenesis procedures in Xenopus. Biol Cell (2008) 1.04
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A BAC-bacterial recombination method to generate physically linked multiple gene reporter DNA constructs. BMC Biotechnol (2009) 0.98
Transgene excision in zebrafish using the phiC31 integrase. Genesis (2010) 0.93
Manipulating the Xenopus genome with transposable elements. Genome Biol (2007) 0.92
Use of a ROSA26:GFP transgenic line for long-term Xenopus fate-mapping studies. J Anat (2006) 0.89
Xenopus: An emerging model for studying congenital heart disease. Birth Defects Res A Clin Mol Teratol (2011) 0.89
Site-directed zebrafish transgenesis into single landing sites with the phiC31 integrase system. Dev Dyn (2013) 0.88
Effect of nuclear localization and hydrodynamic delivery-induced cell division on phiC31 integrase activity. Gene Ther (2009) 0.86
Efficient site-specific transgenesis and enhancer activity tests in medaka using PhiC31 integrase. Development (2013) 0.85
Xenopus, a unique comparative model to explore the role of certain heat shock proteins and non-classical MHC class Ib gene products in immune surveillance. Immunol Res (2009) 0.85
New doxycycline-inducible transgenic lines in Xenopus. Dev Dyn (2011) 0.84
EYA1 mutations associated with the branchio-oto-renal syndrome result in defective otic development in Xenopus laevis. Biol Cell (2010) 0.84
Bacteriophage phiC31 integrase mediated transgenesis in Xenopus laevis for protein expression at endogenous levels. Methods Mol Biol (2009) 0.82
Genome editing for crop improvement: Challenges and opportunities. GM Crops Food (2015) 0.82
Lessons from the lily pad: Using Xenopus to understand heart disease. Drug Discov Today Dis Models (2008) 0.81
Use of phage φC31 integrase as a tool for zebrafish genome manipulation. Methods Cell Biol (2011) 0.81
Transgenesis and neuronal ablation in parasitic nematodes: revolutionary new tools to dissect host-parasite interactions. Parasite Immunol (2008) 0.81
Mutational analysis of highly conserved residues in the phage phiC31 integrase reveals key amino acids necessary for the DNA recombination. PLoS One (2010) 0.80
Transposon transgenesis in Xenopus. Methods (2010) 0.78
Optimized transgenesis in Xenopus laevis/gilli isogenetic clones for immunological studies. Genesis (2011) 0.78
Use of adenovirus for ectopic gene expression in Xenopus. Dev Dyn (2009) 0.78
phiC31 integrase-mediated site-specific recombination in barley. PLoS One (2012) 0.78
Cartilage on the move: cartilage lineage tracing during tadpole metamorphosis. Dev Growth Differ (2012) 0.77
Echocardiographic assessment of cardiac morphology and function in Xenopus. Comp Med (2010) 0.76
Hybrid lentivirus-phiC31-int-NLS vector allows site-specific recombination in murine and human cells but induces DNA damage. PLoS One (2014) 0.76
Frog transgenesis made simple. Nat Methods (2005) 0.76
Reconfiguring gene traps for new tasks using iTRAC. Fly (Austin) (2011) 0.75
Genetic analysis of Xenopus tropicalis. Methods Mol Biol (2012) 0.75
Using ΦC31 integrase to mediate insertion of DNA in Xenopus embryos. Methods Mol Biol (2012) 0.75
Modeling Dominant and Recessive Forms of Retinitis Pigmentosa by Editing Three Rhodopsin-Encoding Genes in Xenopus Laevis Using Crispr/Cas9. Sci Rep (2017) 0.75
Construction of transgenic Drosophila by using the site-specific integrase from phage phiC31. Genetics (2004) 9.98
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Transgenic Xenopus embryos from sperm nuclear transplantations reveal FGF signaling requirements during gastrulation. Development (1996) 5.54
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A phage integrase directs efficient site-specific integration in human cells. Proc Natl Acad Sci U S A (2000) 5.13
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Loss of transcriptional activity of a transgene is accompanied by DNA methylation and histone deacetylation and is prevented by insulators. Genes Dev (1998) 3.70
Site-specific genomic integration in mammalian cells mediated by phage phiC31 integrase. Mol Cell Biol (2001) 3.39
Identification and cloning of localized maternal RNAs from Xenopus eggs. Cell (1985) 3.30
Control of directionality in the site-specific recombination system of the Streptomyces phage phiC31. Mol Microbiol (2000) 2.78
Site-specific genomic integration produces therapeutic Factor IX levels in mice. Nat Biotechnol (2002) 2.54
Site-specific cassette exchange and germline transmission with mouse ES cells expressing phiC31 integrase. Nat Biotechnol (2003) 2.28
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Gene insertion and replacement in Schizosaccharomyces pombe mediated by the Streptomyces bacteriophage phiC31 site-specific recombination system. Mol Genet Genomics (2001) 1.64
A simplified method of generating transgenic Xenopus. Nucleic Acids Res (2000) 1.59
In vivo correction of murine hereditary tyrosinemia type I by phiC31 integrase-mediated gene delivery. Mol Ther (2005) 1.59
The development of Xenopus tropicalis transgenic lines and their use in studying lens developmental timing in living embryos. Development (2000) 1.57
Targeted degradation of mRNA in Xenopus oocytes and embryos directed by modified oligonucleotides: studies of An2 and cyclin in embryogenesis. Nucleic Acids Res (1990) 1.55
Assays for gene function in developing Xenopus embryos. Methods Cell Biol (1991) 1.37
The complete genome sequence of the Streptomyces temperate phage straight phiC31: evolutionary relationships to other viruses. Nucleic Acids Res (1999) 1.35
phiC31 integrase confers genomic integration and long-term transgene expression in rat retina. Invest Ophthalmol Vis Sci (2005) 1.24
A novel approach to plastid transformation utilizes the phiC31 phage integrase. Plant J (2004) 1.00
Specialized and redundant roles of TBP and a vertebrate-specific TBP paralog in embryonic gene regulation in Xenopus. Proc Natl Acad Sci U S A (2004) 1.74
Conserved requirement of Lim1 function for cell movements during gastrulation. Dev Cell (2003) 1.32
Transcription factor AP-2 is an essential and direct regulator of epidermal development in Xenopus. Dev Biol (2002) 1.17
Pitx2c attenuation results in cardiac defects and abnormalities of intestinal orientation in developing Xenopus laevis. Dev Biol (2003) 1.05
TBP paralogs accommodate metazoan- and vertebrate-specific developmental gene regulation. EMBO J (2007) 1.04
Transgenesis procedures in Xenopus. Biol Cell (2008) 1.04
Retinoic acid signaling is essential for formation of the heart tube in Xenopus. Dev Biol (2006) 0.94
Distance and affinity dependence of triplex-induced recombination. Biochemistry (2005) 0.93
Triplex-induced recombination and repair in the pyrimidine motif. Nucleic Acids Res (2005) 0.89
Transient early embryonic expression of Nkx2-5 mutations linked to congenital heart defects in human causes heart defects in Xenopus laevis. Dev Dyn (2007) 0.86
Examining the cardiac NK-2 genes in early heart development. Pediatr Cardiol (2009) 0.86
Characterization of embryonic cardiac pacemaker and atrioventricular conduction physiology in Xenopus laevis using noninvasive imaging. Am J Physiol Heart Circ Physiol (2004) 0.85
Reduction of XNkx2-10 expression leads to anterior defects and malformation of the embryonic heart. Mech Dev (2006) 0.84
EYA1 mutations associated with the branchio-oto-renal syndrome result in defective otic development in Xenopus laevis. Biol Cell (2010) 0.84
Bacteriophage phiC31 integrase mediated transgenesis in Xenopus laevis for protein expression at endogenous levels. Methods Mol Biol (2009) 0.82
Using phiC31 integrase to make transgenic Xenopus laevis embryos. Nat Protoc (2006) 0.82
Lessons from the lily pad: Using Xenopus to understand heart disease. Drug Discov Today Dis Models (2008) 0.81
Chordin affects pronephros development in Xenopus embryos by anteriorizing presomitic mesoderm. Dev Dyn (2007) 0.81
Antisense knockdown of cyclin E does not affect the midblastula transition in Xenopus laevis embryos. Cell Cycle (2005) 0.79
EYA1 expression in the developing inner ear. Ann Otol Rhinol Laryngol (2005) 0.79
Using ΦC31 integrase to mediate insertion of DNA in Xenopus embryos. Methods Mol Biol (2012) 0.75