Interactions between gut peptides and the central melanocortin system in the regulation of energy homeostasis.

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Effects of meals high in carbohydrate, protein, and fat on ghrelin and peptide YY secretion in prepubertal children. J Clin Endocrinol Metab (2009) 1.05

Obesity, gut hormones, and bariatric surgery. World J Surg (2009) 1.04

Pathogenesis of adolescent idiopathic scoliosis in girls - a double neuro-osseous theory involving disharmony between two nervous systems, somatic and autonomic expressed in the spine and trunk: possible dependency on sympathetic nervous system and hormones with implications for medical therapy. Scoliosis (2009) 1.02

Bariatric surgery in a patient with complete MC4R deficiency. Int J Obes (Lond) (2010) 1.01

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Postprandial total ghrelin suppression is modulated by melanocortin signaling in humans. J Clin Endocrinol Metab (2013) 0.82

Systematic Backbone Conformational Constraints on a Cyclic Melanotropin Ligand Leads to Highly Selective Ligands for Multiple Melanocortin Receptors. J Med Chem (2015) 0.81

Solid-phase peptide head-to-side chain cyclodimerization: discovery of C(2)-symmetric cyclic lactam hybrid α-melanocyte-stimulating hormone (MSH)/agouti-signaling protein (ASIP) analogues with potent activities at the human melanocortin receptors. Peptides (2010) 0.79

Central vagal afferent endings mediate reduction of food intake by melanocortin-3/4 receptor agonist. J Neurosci (2014) 0.79

Neuroendorine and Epigentic Mechanisms Subserving Autonomic Imbalance and HPA Dysfunction in the Metabolic Syndrome. Front Neurosci (2016) 0.77

Modulation of orexigenic and anorexigenic peptides gene expression in the rat DVC and hypothalamus by acute immobilization stress. Front Cell Neurosci (2014) 0.77

Metabolic dysfunction following weight-cycling in male mice. Int J Obes (Lond) (2016) 0.75

Gut hormone PYY(3-36) physiologically inhibits food intake. Nature (2002) 8.30

The distribution and mechanism of action of ghrelin in the CNS demonstrates a novel hypothalamic circuit regulating energy homeostasis. Neuron (2003) 6.05

Brain-derived neurotrophic factor regulates energy balance downstream of melanocortin-4 receptor. Nat Neurosci (2003) 4.83

Activation of central melanocortin pathways by fenfluramine. Science (2002) 2.71

Fasting induces a large, leptin-dependent increase in the intrinsic action potential frequency of orexigenic arcuate nucleus neuropeptide Y/Agouti-related protein neurons. Endocrinology (2004) 2.15

Cholecystokinin-mediated suppression of feeding involves the brainstem melanocortin system. Nat Neurosci (2004) 2.14

Peptide YY3-36 inhibits food intake in mice through a melanocortin-4 receptor-independent mechanism. Endocrinology (2004) 1.80

Effect of Agouti-related protein in regulation of the hypothalamic-pituitary-thyroid axis in the melanocortin 4 receptor knockout mouse. Endocrinology (2004) 1.71

Role of the central melanocortin circuitry in adaptive thermogenesis of brown adipose tissue. Endocrinology (2006) 1.71

The central melanocortin system and the integration of short- and long-term regulators of energy homeostasis. Recent Prog Horm Res (2004) 1.60

Neuropeptide W: an anorectic peptide regulated by leptin and metabolic state. Endocrinology (2010) 1.50

The melanocortin-3 receptor is required for entrainment to meal intake. J Neurosci (2008) 1.49

Characterization of a novel binding partner of the melanocortin-4 receptor: attractin-like protein. Biochem J (2003) 1.49

Melanocortin-4 receptor signaling is required for weight loss after gastric bypass surgery. J Clin Endocrinol Metab (2012) 1.46

Creation of a genetic model of obesity in a teleost. FASEB J (2007) 1.35

The regulation of food intake by selective stimulation of the type 3 melanocortin receptor (MC3R). Peptides (2005) 1.31

A role for the endogenous opioid beta-endorphin in energy homeostasis. Endocrinology (2003) 1.31

Characterization of leptin-responsive neurons in the caudal brainstem. Endocrinology (2006) 1.30

Role of leptin and melanocortin signaling in uremia-associated cachexia. J Clin Invest (2005) 1.30

Peripheral administration of PYY(3-36) produces conditioned taste aversion in mice. Cell Metab (2005) 1.29

Pineal-specific agouti protein regulates teleost background adaptation. Proc Natl Acad Sci U S A (2010) 1.27

Obesity-induced inflammation in white adipose tissue is attenuated by loss of melanocortin-3 receptor signaling. Endocrinology (2007) 1.24

Central serotonin and melanocortin pathways regulating energy homeostasis. Ann N Y Acad Sci (2003) 1.24

Multinodal regulation of the arcuate/paraventricular nucleus circuit by leptin. Proc Natl Acad Sci U S A (2010) 1.20

Genetic disruption of gamma-melanocyte-stimulating hormone signaling leads to salt-sensitive hypertension in the mouse. J Clin Invest (2003) 1.17

The role of the central melanocortin system in the regulation of food intake and energy homeostasis: lessons from mouse models. Philos Trans R Soc Lond B Biol Sci (2006) 1.14

Central receptors mediating the cardiovascular actions of melanocyte stimulating hormones. J Hypertens (2006) 1.12

Knockout studies defining different roles for melanocortin receptors in energy homeostasis. Ann N Y Acad Sci (2003) 1.10

Differential role of melanocortin receptor subtypes in cachexia. Endocrinology (2003) 1.10

Characterization of the hyperphagic response to dietary fat in the MC4R knockout mouse. Endocrinology (2011) 1.09

Developmental control of the melanocortin-4 receptor by MRAP2 proteins in zebrafish. Science (2013) 1.03

Agouti-related protein (AGRP) is conserved and regulated by metabolic state in the zebrafish, Danio rerio. Endocrine (2003) 1.00

Conserved neurochemical pathways involved in hypothalamic control of energy homeostasis. J Comp Neurol (2007) 0.99

AgRP and POMC neurons are hypophysiotropic and coordinately regulate multiple endocrine axes in a larval teleost. Cell Metab (2012) 0.98

Melanocortin-3 receptor regulates the normal fasting response. Proc Natl Acad Sci U S A (2012) 0.97

Melanocortin-4 receptor mutations paradoxically reduce preference for palatable foods. Proc Natl Acad Sci U S A (2013) 0.95

Physiological roles of the melanocortin MC₃ receptor. Eur J Pharmacol (2011) 0.94

RM-493, a melanocortin-4 receptor (MC4R) agonist, increases resting energy expenditure in obese individuals. J Clin Endocrinol Metab (2015) 0.94

Melanocortin-5 receptor deficiency promotes defensive behavior in male mice. Horm Behav (2004) 0.93

Regulation of thyrotropin-releasing hormone-expressing neurons in paraventricular nucleus of the hypothalamus by signals of adiposity. Mol Endocrinol (2010) 0.91

Mechanisms of disease: Cytokine and adipokine signaling in uremic cachexia. Nat Clin Pract Nephrol (2006) 0.90

Orexigenic and anorexigenic mechanisms in the control of nutrition in chronic kidney disease. Pediatr Nephrol (2005) 0.90

Ala67Thr polymorphism in the Agouti-related peptide gene is associated with inherited leanness in humans. Am J Med Genet A (2004) 0.89

Gender-specific roles for the melanocortin-3 receptor in the regulation of the mesolimbic dopamine system in mice. Endocrinology (2014) 0.89

Development of a high throughput screen for allosteric modulators of melanocortin-4 receptor signaling using a real time cAMP assay. Eur J Pharmacol (2011) 0.89

Melanocortin-5 receptor deficiency in mice blocks a novel pathway influencing pheromone-induced aggression. Behav Genet (2006) 0.88

Melanocortin-5 receptor deficiency reduces a pheromonal signal for aggression in male mice. Chem Senses (2004) 0.87

PYY3-36 inhibits the action potential firing activity of POMC neurons of arcuate nucleus through postsynaptic Y2 receptors. Cell Metab (2005) 0.84

The anorexigenic fatty acid synthase inhibitor, C75, is a nonspecific neuronal activator. Endocrinology (2003) 0.84

The role of the melanocortin-3 receptor in cachexia. Ann N Y Acad Sci (2003) 0.83

Assessment of a small molecule melanocortin-4 receptor-specific agonist on energy homeostasis. Brain Res (2004) 0.81

Reply to Braasch and Postlethwait: Evolutionary origin of the teleost A2 agouti genes (agouti signaling protein 2 and agouti-related protein 2) remains unclear. Proc Natl Acad Sci U S A (2011) 0.79

Development of an assay for high-throughput energy expenditure monitoring in the zebrafish. Zebrafish (2013) 0.78

Pheromone-induced anorexia in male Syrian hamsters. Am J Physiol Endocrinol Metab (2003) 0.77

De novo design, synthesis, and pharmacology of alpha-melanocyte stimulating hormone analogues derived from somatostatin by a hybrid approach. J Med Chem (2004) 0.77

Zebrafish ghrelin is expressed in pancreatic endocrine cells and regulated by metabolic state. Biochem Biophys Res Commun (2013) 0.76

Shining a light on energy homeostasis. Cell Metab (2011) 0.76

Neuropeptide Y and gamma-melanocyte stimulating hormone (gamma-MSH) share a common pressor mechanism of action. Endocrine (2009) 0.75

QnAs with Roger D. Cone. Proc Natl Acad Sci U S A (2013) 0.75