Published in Toxicon on December 05, 2005
Crystal structure of the Vibrio cholerae cytolysin heptamer reveals common features among disparate pore-forming toxins. Proc Natl Acad Sci U S A (2011) 1.30
The Vibrio cholerae cytolysin promotes chloride secretion from intact human intestinal mucosa. PLoS One (2009) 0.96
Outer membrane vesicles mediate transport of biologically active Vibrio cholerae cytolysin (VCC) from V. cholerae strains. PLoS One (2014) 0.87
Engineered nanoparticles mimicking cell membranes for toxin neutralization. Adv Drug Deliv Rev (2015) 0.81
The Vibrio cholerae cytolysin promotes activation of mast cell (T helper 2) cytokine production. Cell Microbiol (2007) 0.79
Borrelia burgdorferi NapA-driven Th17 cell inflammation in lyme arthritis. Arthritis Rheum (2008) 2.45
G-CSF-stimulated neutrophils are a prominent source of functional BLyS. J Exp Med (2003) 2.31
Equivalent effects of snake PLA2 neurotoxins and lysophospholipid-fatty acid mixtures. Science (2005) 1.92
Anthrax toxins suppress T lymphocyte activation by disrupting antigen receptor signaling. J Exp Med (2005) 1.90
Anthrax toxins: A paradigm of bacterial immune suppression. Trends Immunol (2006) 1.67
Anthrax edema toxin cooperates with lethal toxin to impair cytokine secretion during infection of dendritic cells. J Immunol (2005) 1.59
Anthrax toxin: a tripartite lethal combination. FEBS Lett (2002) 1.54
Screening inhibitors of anthrax lethal factor. Nature (2002) 1.30
Presynaptic enzymatic neurotoxins. J Neurochem (2006) 1.23
The anthrax lethal factor and its MAPK kinase-specific metalloprotease activity. Mol Aspects Med (2009) 1.20
Structure of the neutrophil-activating protein from Helicobacter pylori. J Mol Biol (2002) 1.19
Structure of two iron-binding proteins from Bacillus anthracis. J Biol Chem (2002) 1.16
The neutrophil-activating protein (HP-NAP) of Helicobacter pylori is a potent stimulant of mast cells. Eur J Immunol (2002) 1.16
Anthrax toxins inhibit immune cell chemotaxis by perturbing chemokine receptor signalling. Cell Microbiol (2006) 1.15
Ratio of lethal and edema factors in rabbit systemic anthrax. Toxicon (2008) 1.14
Cell entry and cAMP imaging of anthrax edema toxin. EMBO J (2006) 1.09
The neutrophil-activating protein of Helicobacter pylori crosses endothelia to promote neutrophil adhesion in vivo. J Immunol (2007) 1.06
Entering neurons: botulinum toxins and synaptic vesicle recycling. EMBO Rep (2006) 1.05
The neutrophil-activating protein of Helicobacter pylori. Int J Med Microbiol (2002) 1.05
Interaction with CagF is required for translocation of CagA into the host via the Helicobacter pylori type IV secretion system. Infect Immun (2006) 1.04
Antiepileptic effects of botulinum neurotoxin E. J Neurosci (2005) 1.03
The neutrophil-activating protein of Helicobacter pylori (HP-NAP) activates the MAPK pathway in human neutrophils. Eur J Immunol (2003) 1.02
Internalization and mechanism of action of clostridial toxins in neurons. Neurotoxicology (2005) 1.01
The adenylate cyclase toxins of Bacillus anthracis and Bordetella pertussis promote Th2 cell development by shaping T cell antigen receptor signaling. PLoS Pathog (2009) 1.00
The N-terminal half of the receptor domain of botulinum neurotoxin A binds to microdomains of the plasma membrane. Biochem Biophys Res Commun (2009) 1.00
Potent inhibitors of anthrax lethal factor from green tea. EMBO Rep (2004) 1.00
Botulism. Handb Clin Neurol (2008) 1.00
Presynaptic neurotoxins with enzymatic activities. Handb Exp Pharmacol (2008) 0.98
The multiple cellular activities of the VacA cytotoxin of Helicobacter pylori. Int J Med Microbiol (2004) 0.98
Suppression of T-lymphocyte activation and chemotaxis by the adenylate cyclase toxin of Bordetella pertussis. Infect Immun (2008) 0.97
Traffic of botulinum toxins A and E in excitatory and inhibitory neurons. Traffic (2007) 0.97
Tyrosine-728 and glutamic acid-735 are essential for the metalloproteolytic activity of the lethal factor of Bacillus anthracis. Biochem Biophys Res Commun (2004) 0.97
Where and how do anthrax toxins exit endosomes to intoxicate host cells? Trends Microbiol (2007) 0.96
Assay of diffusion of different botulinum neurotoxin type a formulations injected in the mouse leg. Muscle Nerve (2009) 0.96
The blockade of the neurotransmitter release apparatus by botulinum neurotoxins. Cell Mol Life Sci (2013) 0.96
Transient synaptic silencing of developing striate cortex has persistent effects on visual function and plasticity. J Neurosci (2007) 0.96
VAMP/synaptobrevin cleavage by tetanus and botulinum neurotoxins is strongly enhanced by acidic liposomes. FEBS Lett (2003) 0.95
The Helicobacter pylori VacA cytotoxin activates RBL-2H3 cells by inducing cytosolic calcium oscillations. Cell Microbiol (2005) 0.95
The metalloproteolytic activity of the anthrax lethal factor is substrate-inhibited. J Biol Chem (2003) 0.94
The adjuvant MF59 induces ATP release from muscle that potentiates response to vaccination. Proc Natl Acad Sci U S A (2013) 0.94
Imaging the cell entry of the anthrax oedema and lethal toxins with fluorescent protein chimeras. Cell Microbiol (2010) 0.93
Bothrops snake myotoxins induce a large efflux of ATP and potassium with spreading of cell damage and pain. Proc Natl Acad Sci U S A (2010) 0.92
Different types of botulinum toxin in humans. Mov Disord (2004) 0.92
The concerted action of the Helicobacter pylori cytotoxin VacA and of the v-ATPase proton pump induces swelling of isolated endosomes. Cell Microbiol (2007) 0.91
VacA and HP-NAP, Ying and Yang of Helicobacter pylori-associated gastric inflammation. Clin Chim Acta (2007) 0.91
The Vibrio cholerae haemolysin anion channel is required for cell vacuolation and death. Cell Microbiol (2002) 0.90
Snake phospholipase A2 neurotoxins enter neurons, bind specifically to mitochondria, and open their transition pores. J Biol Chem (2008) 0.90
Anthrax edema toxin modulates PKA- and CREB-dependent signaling in two phases. PLoS One (2008) 0.90
Double anchorage to the membrane and intact inter-chain disulfide bond are required for the low pH induced entry of tetanus and botulinum neurotoxins into neurons. Cell Microbiol (2011) 0.90
Toxicity of botulinum neurotoxins in central nervous system of mice. Toxicon (2003) 0.89
Neuromuscular paralysis and recovery in mice injected with botulinum neurotoxins A and C. Eur J Neurosci (2007) 0.89
Microbiology: death of a chaperone. Nature (2006) 0.88
Crystal structure of antigen TpF1 from Treponema pallidum. Proteins (2006) 0.88
Botulinum neurotoxins and formalin-induced pain: central vs. peripheral effects in mice. Brain Res (2006) 0.87
Bacillus anthracis: balancing innocent research with dual-use potential. Int J Med Microbiol (2008) 0.87
The thioredoxin reductase-thioredoxin system is involved in the entry of tetanus and botulinum neurotoxins in the cytosol of nerve terminals. FEBS Lett (2012) 0.87
Mass spectrometry analysis of the phospholipase A(2) activity of snake pre-synaptic neurotoxins in cultured neurons. J Neurochem (2009) 0.87
Botulinum neurotoxin serotype D is poorly effective in humans: an in vivo electrophysiological study. Clin Neurophysiol (2012) 0.85
Evidence for a radial SNARE super-complex mediating neurotransmitter release at the Drosophila neuromuscular junction. J Cell Sci (2013) 0.85
Botulinum neurotoxin type A is internalized and translocated from small synaptic vesicles at the neuromuscular junction. Mol Neurobiol (2013) 0.85
Calcium influx and mitochondrial alterations at synapses exposed to snake neurotoxins or their phospholipid hydrolysis products. J Biol Chem (2007) 0.84
Snake presynaptic neurotoxins with phospholipase A2 activity induce punctate swellings of neurites and exocytosis of synaptic vesicles. J Cell Sci (2004) 0.83
The C-terminal region of a Lys49 myotoxin mediates Ca2+ influx in C2C12 myotubes. Toxicon (2009) 0.83
Calcium overload in nerve terminals of cultured neurons intoxicated by alpha-latrotoxin and snake PLA2 neurotoxins. Toxicon (2009) 0.83
Diphtheria toxin conformational switching at acidic pH. FEBS J (2014) 0.83
Arg206 of SNAP-25 is essential for neuroexocytosis at the Drosophila melanogaster neuromuscular junction. J Cell Sci (2010) 0.83
Taipoxin induces F-actin fragmentation and enhances release of catecholamines in bovine chromaffin cells. J Neurochem (2003) 0.82
Lipid function at synapses. Curr Opin Neurobiol (2010) 0.82
cAMP imaging of cells treated with pertussis toxin, cholera toxin, and anthrax edema toxin. Biochem Biophys Res Commun (2008) 0.82
Taipoxin induces synaptic vesicle exocytosis and disrupts the interaction of synaptophysin I with VAMP2. Mol Pharmacol (2005) 0.81
The apoptogenic toxin AIP56 is a metalloprotease A-B toxin that cleaves NF-κb P65. PLoS Pathog (2013) 0.81
Why myotoxin-containing snake venoms possess powerful nucleotidases? Biochem Biophys Res Commun (2012) 0.81
The Vibrio cholerae cytolysin promotes activation of mast cell (T helper 2) cytokine production. Cell Microbiol (2007) 0.79
Reversible skeletal neuromuscular paralysis induced by different lysophospholipids. FEBS Lett (2006) 0.79
Pathogenomics: an updated European Research Agenda. Infect Genet Evol (2008) 0.79
Time course and temperature dependence of the membrane translocation of tetanus and botulinum neurotoxins C and D in neurons. Biochem Biophys Res Commun (2012) 0.79
Neutralisation of specific surface carboxylates speeds up translocation of botulinum neurotoxin type B enzymatic domain. FEBS Lett (2013) 0.79
Envenomations by Bothrops and Crotalus snakes induce the release of mitochondrial alarmins. PLoS Negl Trop Dis (2012) 0.79
Glycogen synthase kinase 3 activation is essential for the snake phospholipase A2 neurotoxin-induced secretion in chromaffin cells. Eur J Neurosci (2007) 0.78
Streptococcus pneumoniae induces mast cell degranulation. Int J Med Microbiol (2006) 0.78
The crystal structure of CagS from the Helicobacter pylori pathogenicity island. Proteins (2007) 0.78
Muscle phospholipid hydrolysis by Bothrops asper Asp49 and Lys49 phospholipase A₂ myotoxins--distinct mechanisms of action. FEBS J (2013) 0.78
Paralytic activity of lysophosphatidylcholine from saliva of the waterbug Belostoma anurum. J Exp Biol (2010) 0.77
Peculiar binding of botulinum neurotoxins. ACS Chem Biol (2007) 0.77
Calpains participate in nerve terminal degeneration induced by spider and snake presynaptic neurotoxins. Toxicon (2012) 0.77
Characterization and immunogenicity of the CagF protein of the cag pathogenicity island of Helicobacter pylori. Infect Immun (2002) 0.76
Botulinum neurotoxin serotypes A and C do not affect motor units survival in humans: an electrophysiological study by motor units counting. Clin Neurophysiol (2002) 0.76
Neurotoxicity of inverted-cone shaped lipids. Neurotoxicology (2008) 0.76
Lysophospholipids are evolutionary ancient venom components. Toxicon (2010) 0.76
Botulinum neurotoxins are metalloproteases specific for SNARE proteins involved in neuroexocytosis. Curr Probl Dermatol (2002) 0.76
Electric dipole reorientation in the interaction of botulinum neurotoxins with neuronal membranes. FEBS Lett (2009) 0.75
An update on the mechanism of action of tetanus and botulinum neurotoxins. Acta Chim Slov (2011) 0.75
A lysolecithin/fatty acid mixture promotes and then blocks neurotransmitter release at the Drosophila melanogaster larval neuromuscular junction. Neurosci Lett (2007) 0.75
Editorial. Mol Aspects Med (2009) 0.75
On the quaternary structure of taipoxin and textilotoxin: the advantage of being multiple. Toxicon (2008) 0.75