Published in Toxicol Sci on December 07, 2005
High dietary inorganic phosphate increases lung tumorigenesis and alters Akt signaling. Am J Respir Crit Care Med (2008) 1.05
An integrated understanding of the physiological response to elevated extracellular phosphate. J Cell Physiol (2013) 0.98
Inorganic phosphate and the risk of cancer in the Swedish AMORIS study. BMC Cancer (2013) 0.90
Knockdown of the sodium-dependent phosphate co-transporter 2b (NPT2b) suppresses lung tumorigenesis. PLoS One (2013) 0.82
High dietary inorganic phosphate enhances cap-dependent protein translation, cell-cycle progression, and angiogenesis in the livers of young mice. Am J Physiol Gastrointest Liver Physiol (2008) 0.81
Inorganic Phosphate as a Novel Signaling Molecule with Antiproliferative Action in MDA-MB-231 Breast Cancer Cells. Biores Open Access (2013) 0.78
Inorganic phosphate induces cancer cell mediated angiogenesis dependent on forkhead box protein C2 (FOXC2) regulated osteopontin expression. Mol Carcinog (2014) 0.78
Association of serum inorganic phosphate with sex steroid hormones and vitamin D in a nationally representative sample of men. Andrology (2014) 0.76
Picroside II Inhibits Neuronal Apoptosis and Improves the Morphology and Structure of Brain Tissue following Cerebral Ischemic Injury in Rats. PLoS One (2015) 0.76
Toward improved phosphorus efficiency in monogastrics-interplay of serum, minerals, bone, and immune system after divergent dietary phosphorus supply in swine. Am J Physiol Regul Integr Comp Physiol (2016) 0.75
High dietary phosphate intake induces hypertension and augments exercise pressor reflex function in rats. Am J Physiol Regul Integr Comp Physiol (2016) 0.75
High Inorganic Phosphate Intake Promotes Tumorigenesis at Early Stages in a Mouse Model of Lung Cancer. PLoS One (2015) 0.75
Generation of protein isoform diversity by alternative initiation of translation at non-AUG codons. Biol Cell (2003) 8.81
Antimicrobial effects of silver nanoparticles. Nanomedicine (2007) 6.43
Intravenous delivery of a multi-mechanistic cancer-targeted oncolytic poxvirus in humans. Nature (2011) 4.61
Small-molecule activation of procaspase-3 to caspase-3 as a personalized anticancer strategy. Nat Chem Biol (2006) 3.30
A novel function of the MA-3 domains in transformation and translation suppressor Pdcd4 is essential for its binding to eukaryotic translation initiation factor 4A. Mol Cell Biol (2004) 2.38
The c-myc gene is a direct target of mammalian SWI/SNF-related complexes during differentiation-associated cell cycle arrest. Cancer Res (2006) 2.36
Toxicity and tissue distribution of magnetic nanoparticles in mice. Toxicol Sci (2005) 1.83
A new player in oncogenesis: AUF1/hnRNPD overexpression leads to tumorigenesis in transgenic mice. Cancer Res (2002) 1.81
A single internal ribosome entry site containing a G quartet RNA structure drives fibroblast growth factor 2 gene expression at four alternative translation initiation codons. J Biol Chem (2003) 1.67
Integrative analysis of multiple gene expression profiles applied to liver cancer study. FEBS Lett (2004) 1.63
Dysregulation of ribosome biogenesis and translational capacity is associated with tumor progression of human breast cancer cells. PLoS One (2009) 1.60
Heterogeneous nuclear ribonucleoprotein A1 is a novel internal ribosome entry site trans-acting factor that modulates alternative initiation of translation of the fibroblast growth factor 2 mRNA. J Biol Chem (2004) 1.58
Designed fabrication of multifunctional magnetic gold nanoshells and their application to magnetic resonance imaging and photothermal therapy. Angew Chem Int Ed Engl (2006) 1.54
The p270 (ARID1A/SMARCF1) subunit of mammalian SWI/SNF-related complexes is essential for normal cell cycle arrest. Cancer Res (2005) 1.52
[6]-Gingerol inhibits COX-2 expression by blocking the activation of p38 MAP kinase and NF-kappaB in phorbol ester-stimulated mouse skin. Oncogene (2005) 1.46
A mechanistic proof-of-concept clinical trial with JX-594, a targeted multi-mechanistic oncolytic poxvirus, in patients with metastatic melanoma. Mol Ther (2011) 1.45
Multifunctional nanoparticles possessing a "magnetic motor effect" for drug or gene delivery. Angew Chem Int Ed Engl (2005) 1.44
Antagonistic roles for BRM and BRG1 SWI/SNF complexes in differentiation. J Biol Chem (2009) 1.44
Nanoparticle probes with surface enhanced Raman spectroscopic tags for cellular cancer targeting. Anal Chem (2006) 1.43
Galactosylated chitosan-g-PEI/DNA complexes-loaded poly(organophosphazene) hydrogel as a hepatocyte targeting gene delivery system. Arch Pharm Res (2010) 1.39
Specific targeting, cell sorting, and bioimaging with smart magnetic silica core-shell nanomaterials. Small (2006) 1.39
Unr is required in vivo for efficient initiation of translation from the internal ribosome entry sites of both rhinovirus and poliovirus. J Virol (2003) 1.36
p53 acts as a safeguard of translational control by regulating fibrillarin and rRNA methylation in cancer. Cancer Cell (2013) 1.35
p53 mutant breast cancer patients expressing p53γ have as good a prognosis as wild-type p53 breast cancer patients. Breast Cancer Res (2011) 1.29
Resveratrol inhibits TCDD-induced expression of CYP1A1 and CYP1B1 and catechol estrogen-mediated oxidative DNA damage in cultured human mammary epithelial cells. Carcinogenesis (2004) 1.25
AIMP2/p38, the scaffold for the multi-tRNA synthetase complex, responds to genotoxic stresses via p53. Proc Natl Acad Sci U S A (2008) 1.23
Cellular uptake of magnetic nanoparticle is mediated through energy-dependent endocytosis in A549 cells. J Vet Sci (2006) 1.23
Translational induction of VEGF internal ribosome entry site elements during the early response to ischemic stress. Circ Res (2007) 1.18
Diabetes and fractures: an overshadowed association. Curr Opin Endocrinol Diabetes Obes (2009) 1.17
Multiplex targeting, tracking, and imaging of apoptosis by fluorescent surface enhanced Raman spectroscopic dots. Bioconjug Chem (2007) 1.17
Chitosan-graft-polyethylenimine as a gene carrier. J Control Release (2006) 1.15
Elevated inorganic phosphate stimulates Akt-ERK1/2-Mnk1 signaling in human lung cells. Am J Respir Cell Mol Biol (2006) 1.14
Size-dependent tissue kinetics of PEG-coated gold nanoparticles. Toxicol Appl Pharmacol (2010) 1.14
Analysis of the extracellular matrix vesicle proteome in mineralizing osteoblasts. J Cell Physiol (2007) 1.14
Cancer-associated splicing variant of tumor suppressor AIMP2/p38: pathological implication in tumorigenesis. PLoS Genet (2011) 1.12
Body distribution of inhaled fluorescent magnetic nanoparticles in the mice. J Occup Health (2008) 1.10
Internal ribosome entry site structural motifs conserved among mammalian fibroblast growth factor 1 alternatively spliced mRNAs. Mol Cell Biol (2004) 1.09
Aerosol delivery of urocanic acid-modified chitosan/programmed cell death 4 complex regulated apoptosis, cell cycle, and angiogenesis in lungs of K-ras null mice. Mol Cancer Ther (2006) 1.09
Zinc oxide nanoparticle induced autophagic cell death and mitochondrial damage via reactive oxygen species generation. Toxicol In Vitro (2013) 1.08
Galactosylated poly(ethylene glycol)-chitosan-graft-polyethylenimine as a gene carrier for hepatocyte-targeting. J Control Release (2008) 1.08
Elevated phosphate activates N-ras and promotes cell transformation and skin tumorigenesis. Cancer Prev Res (Phila) (2010) 1.07
A biodegradable poly(ester amine) based on polycaprolactone and polyethylenimine as a gene carrier. Biomaterials (2006) 1.06
High dietary inorganic phosphate increases lung tumorigenesis and alters Akt signaling. Am J Respir Crit Care Med (2008) 1.05
Association of LETM1 and MRPL36 contributes to the regulation of mitochondrial ATP production and necrotic cell death. Cancer Res (2009) 1.05
AU-rich elements regulate Drosophila gene expression. Mol Cell Biol (2009) 1.05
High prevalence of hepatitis B virus infection in patients with B-cell non-Hodgkin's lymphoma in Korea. J Med Virol (2008) 1.04
A combined proteome and microarray investigation of inorganic phosphate-induced pre-osteoblast cells. Mol Cell Proteomics (2005) 1.03
A "liaison dangereuse" between AUF1/hnRNPD and the oncogenic tyrosine kinase NPM-ALK. Blood (2006) 1.02
Mannosylated polyethylenimine coupled mesoporous silica nanoparticles for receptor-mediated gene delivery. Int J Pharm (2008) 1.01
FGF2 translationally induced by hypoxia is involved in negative and positive feedback loops with HIF-1alpha. PLoS One (2008) 1.00
New method to prepare very stable and biocompatible fluorescent silica nanoparticles. Chem Commun (Camb) (2009) 1.00
Magnetic nanoparticles: an update of application for drug delivery and possible toxic effects. Arch Toxicol (2011) 1.00
Use and comparison of different internal ribosomal entry sites (IRES) in tricistronic retroviral vectors. BMC Biotechnol (2004) 0.99
The suppression of lung tumorigenesis by aerosol-delivered folate-chitosan-graft-polyethylenimine/Akt1 shRNA complexes through the Akt signaling pathway. Biomaterials (2009) 0.99
An integrated understanding of the physiological response to elevated extracellular phosphate. J Cell Physiol (2013) 0.98
Hyperglycemia upregulates translation of the fibroblast growth factor 2 mRNA in mouse aorta via internal ribosome entry site. FASEB J (2004) 0.98
Testosterone regulates FGF-2 expression during testis maturation by an IRES-dependent translational mechanism. FASEB J (2006) 0.97
High dietary inorganic phosphate affects lung through altering protein translation, cell cycle, and angiogenesis in developing mice. Toxicol Sci (2007) 0.97
Chondroitin sulfate extracted from the Styela clava tunic suppresses TNF-alpha-induced expression of inflammatory factors, VCAM-1 and iNOS by blocking Akt/NF-kappaB signal in JB6 cells. Cancer Lett (2008) 0.97
Mannosylated chitosan nanoparticle-based cytokine gene therapy suppressed cancer growth in BALB/c mice bearing CT-26 carcinoma cells. Mol Cancer Ther (2006) 0.97
HuR-mediated control of C/EBPbeta mRNA stability and translation in ALK-positive anaplastic large cell lymphomas. Mol Cancer Res (2011) 0.97
Poly(beta-amino ester) as a carrier for si/shRNA delivery in lung cancer cells. Biomaterials (2008) 0.96
Dominant-negative activator protein 1 (TAM67) targets cyclooxygenase-2 and osteopontin under conditions in which it specifically inhibits tumorigenesis. Cancer Res (2007) 0.96
Bioactive silica nanoparticles promote osteoblast differentiation through stimulation of autophagy and direct association with LC3 and p62. ACS Nano (2014) 0.96
Association between dietary patterns and blood lipid profiles in Korean adults with type 2 diabetes. J Korean Med Sci (2011) 0.96
Roles of protein kinase B/Akt in lung cancer. Front Biosci (Elite Ed) (2010) 0.96
Poly(ester amine)-mediated, aerosol-delivered Akt1 small interfering RNA suppresses lung tumorigenesis. Am J Respir Crit Care Med (2008) 0.96
Aerosol delivery of glucosylated polyethylenimine/phosphatase and tensin homologue deleted on chromosome 10 complex suppresses Akt downstream pathways in the lung of K-ras null mice. Cancer Res (2004) 0.95
Impaired gametogenesis in mice that overexpress the RNA-binding protein HuR. EMBO Rep (2003) 0.95
Identification of the homeobox protein Prx1 (MHox, Prrx-1) as a regulator of osterix expression and mediator of tumor necrosis factor α action in osteoblast differentiation. J Bone Miner Res (2011) 0.93
Temporally regulated traffic of HuR and its associated ARE-containing mRNAs from the chromatoid body to polysomes during mouse spermatogenesis. PLoS One (2009) 0.93
Antitumor effects of genetically engineered stem cells expressing yeast cytosine deaminase in lung cancer brain metastases via their tumor-tropic properties. Oncol Rep (2012) 0.93
Toxicity and clearance of intratracheally administered multiwalled carbon nanotubes from murine lung. J Toxicol Environ Health A (2010) 0.93
Impaired embryonic development in mice overexpressing the RNA-binding protein TIAR. PLoS One (2010) 0.92
Receptor-mediated gene delivery by folate-PEG-baculovirus in vitro. J Biotechnol (2007) 0.92
Beclin1-induced autophagy abrogates radioresistance of lung cancer cells by suppressing osteopontin. J Radiat Res (2012) 0.91
Mannosylated chitosan-graft-polyethylenimine as a gene carrier for Raw 264.7 cell targeting. Int J Pharm (2009) 0.91
Quantitative proteomic analysis of inorganic phosphate-induced murine MC3T3-E1 osteoblast cells. Electrophoresis (2004) 0.91
Acute pulmonary toxicity and body distribution of inhaled metallic silver nanoparticles. Toxicol Res (2012) 0.90
Inhibition of cytokine-induced IkappaB kinase activation as a mechanism contributing to the anti-atherogenic activity of tilianin in hyperlipidemic mice. Atherosclerosis (2005) 0.90
Dietary fish oil alleviates soleus atrophy during immobilization in association with Akt signaling to p70s6k and E3 ubiquitin ligases in rats. Appl Physiol Nutr Metab (2010) 0.90