Identification of a gene on chromosome 12q22 uniquely overexpressed in chronic lymphocytic leukemia.

PubWeight™: 1.16‹?› | Rank: Top 10%

🔗 View Article (PMID 16339396)

Published in Blood on December 08, 2005

Authors

Anne Mette Buhl1, Jesper Jurlander, Flemming S Jørgensen, Anne Marie Ottesen, Jack B Cowland, Lise Mette Gjerdrum, Brian V Hansen, Henrik Leffers

Author Affiliations

1: Department of Hematology, 4041, Rigshospitalet, Blegdamsvej 9, DK-2100 Copenhagen, DK. am.buhl@get2net.dk

Articles citing this

Recent de novo origin of human protein-coding genes. Genome Res (2009) 2.36

Evolution of genetic and genomic features unique to the human lineage. Nat Rev Genet (2012) 1.44

Intrinsic and extrinsic factors influencing the clinical course of B-cell chronic lymphocytic leukemia: prognostic markers with pathogenetic relevance. J Transl Med (2009) 1.35

Darwinian alchemy: Human genes from noncoding DNA. Genome Res (2009) 1.18

LPL is the strongest prognostic factor in a comparative analysis of RNA-based markers in early chronic lymphocytic leukemia. Haematologica (2011) 0.93

Gene expression factors as predictors of genetic risk and survival in chronic lymphocytic leukemia. Haematologica (2009) 0.91

The CLLU1 expression level is a stable and inherent feature of the chronic lymphocytic leukemia clone. Leukemia (2009) 0.88

CLLU1 expression has prognostic value in chronic lymphocytic leukemia after first-line therapy in younger patients and in those with mutated IGHV genes. Haematologica (2012) 0.87

New genes from non-coding sequence: the role of de novo protein-coding genes in eukaryotic evolutionary innovation. Philos Trans R Soc Lond B Biol Sci (2015) 0.87

Great ape genomics. ILAR J (2013) 0.87

Open questions in the study of de novo genes: what, how and why. Nat Rev Genet (2016) 0.81

Analysis of CLLU1 expression levels before and after therapy in patients with chronic lymphocytic leukemia. Eur J Haematol (2011) 0.78

Integrated analyses of gene expression and genetic association studies in a founder population. Hum Mol Genet (2016) 0.75

Expression of evolutionarily novel genes in tumors. Infect Agent Cancer (2016) 0.75

Articles by these authors

Liver is the major source of elevated serum lipocalin-2 levels after bacterial infection or partial hepatectomy: a critical role for IL-6/STAT3. Hepatology (2015) 3.10

FDG-PET after two cycles of chemotherapy predicts treatment failure and progression-free survival in Hodgkin lymphoma. Blood (2005) 2.92

Common variants at 2q37.3, 8q24.21, 15q21.3 and 16q24.1 influence chronic lymphocytic leukemia risk. Nat Genet (2010) 2.45

Stereotyped B-cell receptors in one-third of chronic lymphocytic leukemia: a molecular classification with implications for targeted therapies. Blood (2012) 2.14

Vitamin D receptor and vitamin D metabolizing enzymes are expressed in the human male reproductive tract. Hum Reprod (2010) 2.00

Intrauterine exposure to mild analgesics is a risk factor for development of male reproductive disorders in human and rat. Hum Reprod (2010) 1.97

The endocytic receptor megalin binds the iron transporting neutrophil-gelatinase-associated lipocalin with high affinity and mediates its cellular uptake. FEBS Lett (2005) 1.96

Wound healing and expression of antimicrobial peptides/polypeptides in human keratinocytes, a consequence of common growth factors. J Immunol (2003) 1.88

Do perfluoroalkyl compounds impair human semen quality? Environ Health Perspect (2009) 1.81

CLLU1 expression levels predict time to initiation of therapy and overall survival in chronic lymphocytic leukemia. Eur J Haematol (2006) 1.66

Screening for copy-number alterations and loss of heterozygosity in chronic lymphocytic leukemia--a comparative study of four differently designed, high resolution microarray platforms. Genes Chromosomes Cancer (2008) 1.66

Embryonic stem cell-like features of testicular carcinoma in situ revealed by genome-wide gene expression profiling. Cancer Res (2004) 1.56

Long-term molecular remissions in patients with indolent lymphoma treated with rituximab as a single agent or in combination with interferon alpha-2a: a randomized phase II study from the Nordic Lymphoma Group. Leuk Lymphoma (2008) 1.53

Is human fecundity declining? Int J Androl (2006) 1.52

From embryonic stem cells to testicular germ cell cancer-- should we be concerned? Int J Androl (2006) 1.48

Quality of life in patients with diffuse large B-cell lymphoma treated with dose-dense chemotherapy is only affected temporarily. Leuk Lymphoma (2011) 1.47

Emerging endocrine disrupters: perfluoroalkylated substances. Int J Androl (2008) 1.46

The chimeric anti-CD20 antibody rituximab induces apoptosis in B-cell chronic lymphocytic leukemia cells through a p38 mitogen activated protein-kinase-dependent mechanism. Blood (2002) 1.43

Lack of association between the MDM2 promoter polymorphism SNP309 and clinical outcome in chronic lymphocytic leukemia. Leuk Res (2009) 1.43

Study on the binding of Thioflavin T to beta-sheet-rich and non-beta-sheet cavities. J Struct Biol (2006) 1.37

Analysis of gene expression profiles of microdissected cell populations indicates that testicular carcinoma in situ is an arrested gonocyte. Cancer Res (2009) 1.35

Induction of neutrophil gelatinase-associated lipocalin expression by co-stimulation with interleukin-17 and tumor necrosis factor-alpha is controlled by IkappaB-zeta but neither by C/EBP-beta nor C/EBP-delta. J Biol Chem (2010) 1.34

Mutational mapping and modeling of the binding site for (S)-citalopram in the human serotonin transporter. J Biol Chem (2009) 1.33

Neutrophil gelatinase-associated lipocalin is expressed in osteoarthritis and forms a complex with matrix metalloproteinase 9. Arthritis Rheum (2007) 1.30

The in vivo profile of transcription factors during neutrophil differentiation in human bone marrow. Blood (2003) 1.30

Transcription factor AP-2gamma is a developmentally regulated marker of testicular carcinoma in situ and germ cell tumors. Clin Cancer Res (2004) 1.27

Array-based genomic screening at diagnosis and during follow-up in chronic lymphocytic leukemia. Haematologica (2011) 1.25

Neutrophil gelatinase-associated lipocalin, a siderophore-binding eukaryotic protein. Biometals (2006) 1.24

Lipocalin 2 is protective against E. coli pneumonia. Respir Res (2010) 1.19

On mouse and man: neutrophil gelatinase associated lipocalin is not involved in apoptosis or acute response. Eur J Haematol (2005) 1.17

Olfactomedin 4 defines a subset of human neutrophils. J Leukoc Biol (2011) 1.15

Histone deacetylase 1, 2, 6 and acetylated histone H4 in B- and T-cell lymphomas. Histopathology (2009) 1.14

Neutrophil gelatinase-associated lipocalin is a marker for dysregulated keratinocyte differentiation in human skin. Exp Dermatol (2002) 1.14

Presumed pluripotency markers UTF-1 and REX-1 are expressed in human adult testes and germ cell neoplasms. Hum Reprod (2008) 1.13

Dual effects of phytoestrogens result in u-shaped dose-response curves. Environ Health Perspect (2002) 1.12

Origin of pluripotent germ cell tumours: the role of microenvironment during embryonic development. Mol Cell Endocrinol (2008) 1.11

Analysis of cell-type-specific gene expression during mouse spermatogenesis. Biol Reprod (2004) 1.09

Frequent polymorphism of the mitochondrial DNA polymerase gamma gene (POLG) in patients with normal spermiograms and unexplained subfertility. Hum Reprod (2004) 1.08

Identity of M2A (D2-40) antigen and gp36 (Aggrus, T1A-2, podoplanin) in human developing testis, testicular carcinoma in situ and germ-cell tumours. Virchows Arch (2006) 1.07

High-density screening reveals a different spectrum of genomic aberrations in chronic lymphocytic leukemia patients with 'stereotyped' IGHV3-21 and IGHV4-34 B-cell receptors. Haematologica (2010) 1.03

CLLU1 expression analysis adds prognostic information to risk prediction in chronic lymphocytic leukemia. Blood (2007) 1.03

Alpha-1-antitrypsin is produced by human neutrophil granulocytes and their precursors and liberated during granule exocytosis. Eur J Haematol (2011) 1.02

An ELISA for SGP28/CRISP-3, a cysteine-rich secretory protein in human neutrophils, plasma, and exocrine secretions. J Immunol Methods (2002) 1.01

Identification and expression profiling of 10 novel spermatid expressed CYPT genes. Mol Reprod Dev (2006) 0.99

The sensitivity of the child to sex steroids: possible impact of exogenous estrogens. Hum Reprod Update (2006) 0.99

Determination of phthalate monoesters in human milk, consumer milk, and infant formula by tandem mass spectrometry (LC-MS-MS). Anal Bioanal Chem (2005) 0.98

Ficolin-1 is present in a highly mobilizable subset of human neutrophil granules and associates with the cell surface after stimulation with fMLP. J Leukoc Biol (2009) 0.97

Characterization and localization of cysteine-rich secretory protein 3 (CRISP-3) in the human male reproductive tract. J Androl (2005) 0.97

TP53 Mutations are infrequent in newly diagnosed chronic lymphocytic leukemia. Leuk Res (2010) 0.96

A genome-wide association study of men with symptoms of testicular dysgenesis syndrome and its network biology interpretation. J Med Genet (2011) 0.96

Expression of the vitamin D receptor, 25-hydroxylases, 1alpha-hydroxylase and 24-hydroxylase in the human kidney and renal clear cell cancer. J Steroid Biochem Mol Biol (2010) 0.96

Assessing the relative importance of the biophysical properties of amino acid substitutions associated with human genetic disease. Hum Mutat (2002) 0.95

Many putative endocrine disruptors inhibit prostaglandin synthesis. Environ Health Perspect (2010) 0.94

LPL is the strongest prognostic factor in a comparative analysis of RNA-based markers in early chronic lymphocytic leukemia. Haematologica (2011) 0.93

Verification that common variation at 2q37.1, 6p25.3, 11q24.1, 15q23, and 19q13.32 influences chronic lymphocytic leukaemia risk. Br J Haematol (2010) 0.93

Testicular dysgenesis syndrome and the origin of carcinoma in situ testis. Int J Androl (2008) 0.93

Neutrophils and keratinocytes in innate immunity--cooperative actions to provide antimicrobial defense at the right time and place. J Leukoc Biol (2004) 0.92

Evaluation and comparison of 3D-QSAR CoMSIA models for CDK1, CDK5, and GSK-3 inhibition by paullones. J Med Chem (2004) 0.91

High-resolution comparative genomic hybridization detects extra chromosome arm 12p material in most cases of carcinoma in situ adjacent to overt germ cell tumors, but not before the invasive tumor development. Genes Chromosomes Cancer (2003) 0.91

No effect of NGAL/lipocalin-2 on aggressiveness of cancer in the MMTV-PyMT/FVB/N mouse model for breast cancer. PLoS One (2012) 0.90

Molecular characterization of neoplastic and normal "sister" lymphoblastoid B-cell lines from chronic lymphocytic leukemia. Leuk Lymphoma (2013) 0.90

Levetiracetam attenuates hippocampal expression of synaptic plasticity-related immediate early and late response genes in amygdala-kindled rats. BMC Neurosci (2010) 0.90

No AZF deletion in 160 patients with testicular germ cell neoplasia. Mol Hum Reprod (2003) 0.89

Kaposi sarcoma-associated herpes virus targets the lymphotactin receptor with both a broad spectrum antagonist vCCL2 and a highly selective and potent agonist vCCL3. J Biol Chem (2007) 0.89

Low salivary dehydroepiandrosterone and androgen-regulated cysteine-rich secretory protein 3 levels in Sjögren's syndrome. Arthritis Rheum (2007) 0.89

Analysis of the polymorphic CAG repeat length in the androgen receptor gene in patients with testicular germ cell cancer. Int J Cancer (2002) 0.89

MicroRNA expression profiling of carcinoma in situ cells of the testis. Endocr Relat Cancer (2012) 0.89

Optimizing staining protocols for laser microdissection of specific cell types from the testis including carcinoma in situ. PLoS One (2009) 0.88

Analysis of SOX2 expression in developing human testis and germ cell neoplasia. Int J Dev Biol (2010) 0.88

Prodefensins are matrix proteins of specific granules in human neutrophils. J Leukoc Biol (2005) 0.88

miRNA-130a regulates C/EBP-ε expression during granulopoiesis. Blood (2014) 0.88

MicroRNA profiling in human neutrophils during bone marrow granulopoiesis and in vivo exudation. PLoS One (2013) 0.88

Serglycin participates in retention of α-defensin in granules during myelopoiesis. Blood (2011) 0.86

New leads of metallo-beta-lactamase inhibitors from structure-based pharmacophore design. Bioorg Med Chem (2005) 0.86

Gene expression profiles of mouse spermatogenesis during recovery from irradiation. Reprod Biol Endocrinol (2009) 0.85

Genomic and gene expression signature of the pre-invasive testicular carcinoma in situ. Cell Tissue Res (2005) 0.85

Genome-wide assessment of the association of rare and common copy number variations to testicular germ cell cancer. Front Endocrinol (Lausanne) (2013) 0.85

Distinct gene expression profiles in subsets of chronic lymphocytic leukemia expressing stereotyped IGHV4-34 B-cell receptors. Haematologica (2010) 0.85

The exon 3 deleted growth hormone receptor gene is associated with small birth size and early pubertal onset in healthy boys. J Clin Endocrinol Metab (2010) 0.85

The secretory leukocyte protease inhibitor (SLPI) and the secondary granule protein lactoferrin are synthesized in myelocytes, colocalize in subcellular fractions of neutrophils, and are coreleased by activated neutrophils. J Leukoc Biol (2008) 0.84

Propionic acid secreted from propionibacteria induces NKG2D ligand expression on human-activated T lymphocytes and cancer cells. J Immunol (2009) 0.84

OCT4 and downstream factors are expressed in human somatic urogenital epithelia and in culture of epididymal spheres. Mol Hum Reprod (2010) 0.83

CAG repeat length in androgen-receptor gene and reproductive variables in fertile and infertile men. Lancet (2002) 0.83

How myeloma cells escape bisphosphonate-mediated killing: development of specific resistance with preserved sensitivity to conventional chemotherapeutics. Br J Haematol (2003) 0.83

Vitamin D metabolism and effects on pluripotency genes and cell differentiation in testicular germ cell tumors in vitro and in vivo. Neoplasia (2012) 0.83

CDH1 (E-cadherin) in testicular germ cell neoplasia: suppressed translation of mRNA in pre-invasive carcinoma in situ but increased protein levels in advanced tumours. APMIS (2006) 0.83

All-trans retinoic acid-induced expression of bactericidal/permeability-increasing protein (BPI) in human myeloid cells correlates to binding of C/EBPbeta and C/EBPepsilon to the BPI promoter. J Leukoc Biol (2006) 0.82

Combination of two anti-CD5 monoclonal antibodies synergistically induces complement-dependent cytotoxicity of chronic lymphocytic leukaemia cells. Br J Haematol (2013) 0.82

Estrogenic effect of soy isoflavones on mammary gland morphogenesis and gene expression profile. Toxicol Sci (2006) 0.82

Current approaches for detection of carcinoma in situ testis. Int J Androl (2007) 0.82

Improved gene expression signature of testicular carcinoma in situ. Int J Androl (2007) 0.82