Zhong Pei

Author PubWeight™ 67.91‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Kinase activity of mutant LRRK2 mediates neuronal toxicity. Nat Neurosci 2006 5.32
2 Aggregated alpha-synuclein activates microglia: a process leading to disease progression in Parkinson's disease. FASEB J 2005 3.60
3 Leucine-rich repeat kinase 2 (LRRK2) interacts with parkin, and mutant LRRK2 induces neuronal degeneration. Proc Natl Acad Sci U S A 2005 3.00
4 Endoplasmic reticulum stress and mitochondrial cell death pathways mediate A53T mutant alpha-synuclein-induced toxicity. Hum Mol Genet 2005 1.92
5 Microglial NADPH oxidase is a novel target for femtomolar neuroprotection against oxidative stress. FASEB J 2005 1.15
6 Depletion of CBP is directly linked with cellular toxicity caused by mutant huntingtin. Neurobiol Dis 2006 1.14
7 New-onset constipation at acute stage after first stroke: incidence, risk factors, and impact on the stroke outcome. Stroke 2009 1.08
8 Beclin 1 knockdown inhibits autophagic activation and prevents the secondary neurodegenerative damage in the ipsilateral thalamus following focal cerebral infarction. Autophagy 2012 1.03
9 Progression of pathological changes in the middle cerebellar peduncle by diffusion tensor imaging correlates with lesser motor gains after pontine infarction. Neurorehabil Neural Repair 2009 0.99
10 CT and MR findings in HIV-negative neurosyphilis. Eur J Radiol 2007 0.98
11 A novel marine compound xyloketal B protects against oxidized LDL-induced cell injury in vitro. Biochem Pharmacol 2009 0.98
12 Nonmotor symptoms are independently associated with impaired health-related quality of life in Chinese patients with Parkinson's disease. Mov Disord 2010 0.98
13 Enhanced angiogenesis with dl-3n-butylphthalide treatment after focal cerebral ischemia in RHRSP. Brain Res 2009 0.97
14 Longitudinal investigations on the anterograde and retrograde degeneration in the pyramidal tract following pontine infarction with diffusion tensor imaging. Cerebrovasc Dis 2008 0.96
15 MPP+-induced COX-2 activation and subsequent dopaminergic neurodegeneration. FASEB J 2005 0.96
16 Physical exercise improves functional recovery through mitigation of autophagy, attenuation of apoptosis and enhancement of neurogenesis after MCAO in rats. BMC Neurosci 2013 0.95
17 Protective effects of xyloketal B against MPP+-induced neurotoxicity in Caenorhabditis elegans and PC12 cells. Brain Res 2010 0.95
18 Design and synthesis of novel xyloketal derivatives and their vasorelaxing activities in rat thoracic aorta and angiogenic activities in zebrafish angiogenesis screen. J Med Chem 2010 0.94
19 Nogo-A is involved in secondary axonal degeneration of thalamus in hypertensive rats with focal cortical infarction. Neurosci Lett 2007 0.94
20 DL-3-n-butylphthalide protects endothelial cells against oxidative/nitrosative stress, mitochondrial damage and subsequent cell death after oxygen glucose deprivation in vitro. Brain Res 2009 0.93
21 Xyloketal B exhibits its antioxidant activity through induction of HO-1 in vascular endothelial cells and zebrafish. Mar Drugs 2013 0.91
22 Early detection of secondary damage in ipsilateral thalamus after acute infarction at unilateral corona radiata by diffusion tensor imaging and magnetic resonance spectroscopy. BMC Neurol 2011 0.91
23 Marine compound Xyloketal B protects PC12 cells against OGD-induced cell damage. Brain Res 2009 0.91
24 Synthesis and neuroprotective action of xyloketal derivatives in Parkinson's disease models. Mar Drugs 2013 0.90
25 NADPH oxidase inhibitor DPI is neuroprotective at femtomolar concentrations through inhibition of microglia over-activation. Parkinsonism Relat Disord 2007 0.89
26 Autophagosomes accumulation is associated with β-amyloid deposits and secondary damage in the thalamus after focal cortical infarction in hypertensive rats. J Neurochem 2011 0.89
27 Decrease in the production of β-amyloid by berberine inhibition of the expression of β-secretase in HEK293 cells. BMC Neurosci 2011 0.89
28 COX-2-deficient mice are less prone to MPTP-neurotoxicity than wild-type mice. Neuroreport 2003 0.89
29 Reactive microgliosis participates in MPP+-induced dopaminergic neurodegeneration: role of 67 kDa laminin receptor. FASEB J 2006 0.89
30 Neurogenesis and angiogenesis within the ipsilateral thalamus with secondary damage after focal cortical infarction in hypertensive rats. J Cereb Blood Flow Metab 2009 0.89
31 Longitudinal cortical volume changes correlate with motor recovery in patients after acute local subcortical infarction. Stroke 2013 0.89
32 Morphological analysis in patients with sciatica: a magnetic resonance imaging study using three-dimensional high-resolution diffusion-weighted magnetic resonance neurography techniques. Spine (Phila Pa 1976) 2009 0.88
33 The beta-lactam antibiotic, ceftriaxone, provides neuroprotective potential via anti-excitotoxicity and anti-inflammation response in a rat model of traumatic brain injury. J Trauma Acute Care Surg 2012 0.88
34 Serum uric acid levels of patients with multiple sclerosis and other neurological diseases. Mult Scler 2007 0.88
35 dl-3n-Butylphthalide promotes angiogenesis via the extracellular signal-regulated kinase 1/2 and phosphatidylinositol 3-kinase/Akt-endothelial nitric oxide synthase signaling pathways. J Cardiovasc Pharmacol 2012 0.87
36 Cognitive impairment is common in Parkinson's disease without dementia in the early and middle stages in a Han Chinese cohort. Parkinsonism Relat Disord 2011 0.85
37 Exogenous kallikrein enhances neurogenesis and angiogenesis in the subventricular zone and the peri-infarction region and improves neurological function after focal cortical infarction in hypertensive rats. Brain Res 2008 0.85
38 Nogo-A is associated with secondary degeneration of substantia nigra in hypertensive rats with focal cortical infarction. Brain Res 2012 0.85
39 Peroxisome proliferator activated receptor (PPAR)-γ co-activator 1-α and hypoxia induced factor-1α mediate neuro- and vascular protection by hypoxic preconditioning in vitro. Brain Res 2012 0.84
40 Baicalein reduces E46K alpha-synuclein aggregation in vitro and protects cells against E46K alpha-synuclein toxicity in cell models of familiar Parkinsonism. J Neurochem 2010 0.84
41 Marine cyclotripeptide X-13 promotes angiogenesis in zebrafish and human endothelial cells via PI3K/Akt/eNOS signaling pathways. Mar Drugs 2012 0.83
42 LRRK2 G2385R and LRRK2 R1628P increase risk of Parkinson's disease in a Han Chinese population from Southern Mainland China. Parkinsonism Relat Disord 2012 0.83
43 The genes for gibberellin biosynthesis in wheat. Funct Integr Genomics 2011 0.83
44 AlzPlatform: an Alzheimer's disease domain-specific chemogenomics knowledgebase for polypharmacology and target identification research. J Chem Inf Model 2014 0.82
45 Reduction of β-amyloid deposits by γ-secretase inhibitor is associated with the attenuation of secondary damage in the ipsilateral thalamus and sensory functional improvement after focal cortical infarction in hypertensive rats. J Cereb Blood Flow Metab 2010 0.82
46 Ebselen attenuates oxidative DNA damage and enhances its repair activity in the thalamus after focal cortical infarction in hypertensive rats. Brain Res 2007 0.81
47 Delayed decompressive craniectomy improves the long-term outcomes in hypertensive rats with space-occupying cerebral infarction. Neurocrit Care 2007 0.81
48 The study on the frontoparietal networks by continuous theta burst stimulation in healthy human subjects. Behav Brain Res 2012 0.81
49 Endostatin expression in neurons during the early stage of cerebral ischemia is associated with neuronal apoptotic cell death in adult hypertensive rat model of stroke. Brain Res 2009 0.80
50 Melatonin protects against rotenone-induced cell injury via inhibition of Omi and Bax-mediated autophagy in Hela cells. J Pineal Res 2011 0.80
51 Cyclooxygenase-1 gene knockout does not alter middle cerebral artery occlusion in a mouse stroke model. Neurosci Lett 2002 0.79
52 Blockade of EphB2 enhances neurogenesis in the subventricular zone and improves neurological function after cerebral cortical infarction in hypertensive rats. Brain Res 2008 0.79
53 Decrease of tight junction integrity in the ipsilateral thalamus during the acute stage after focal infarction and ablation of the cerebral cortex in rats. Clin Exp Pharmacol Physiol 2011 0.79
54 Abnormalities of magnetic resonance spectroscopy and diffusion tensor imaging are correlated with executive dysfunction in patients with ischemic leukoaraiosis. J Clin Neurosci 2012 0.78
55 LRRK2 R1398H polymorphism is associated with decreased risk of Parkinson's disease in a Han Chinese population. Parkinsonism Relat Disord 2010 0.78
56 Visuospatial attention deficit in patients with local brain lesions. Brain Res 2010 0.78
57 Scutellarin attenuates hypertension-induced expression of brain Toll-like receptor 4/nuclear factor kappa B. Mediators Inflamm 2013 0.78
58 Long-term Efficacy of Subthalamic Nucleus Deep Brain Stimulation in Parkinson's Disease: A 5-year Follow-up Study in China. Chin Med J (Engl) 2015 0.77
59 Excessive blinking as an initial manifestation of juvenile Huntington's disease. Neurol Sci 2008 0.77
60 Association between improved trunk stability and walking capacity using ankle-foot orthosis in hemiparetic patients with stroke: evidence from three-dimensional gait analysis. Chin Med J (Engl) 2013 0.77
61 Lifespan extension by n-butanol extract from seed of Platycladus orientalis in Caenorhabditis elegans. J Ethnopharmacol 2013 0.77
62 Early stage transplantation of bone marrow cells markedly ameliorates copper metabolism and restores liver function in a mouse model of Wilson disease. BMC Gastroenterol 2011 0.77
63 Frontoparietal regions may become hypoactive after intermittent theta burst stimulation over the contralateral homologous cortex in humans. J Neurophysiol 2013 0.76
64 Stroke-prone renovascular hypertensive rat as an animal model for stroke studies: from artery to brain. J Neurol Sci 2013 0.76
65 Absence of mutations in exon 6 of the TARDBP gene in 207 Chinese patients with sporadic amyotrohic lateral sclerosis. PLoS One 2013 0.76
66 LRRK2 A419V is not associated with Parkinson's disease in different Chinese populations. PLoS One 2012 0.75
67 Salvianolic acid A, a polyphenolic derivative from Salvia miltiorrhiza bunge, as a multifunctional agent for the treatment of Alzheimer's disease. Mol Divers 2013 0.75
68 Hypoxic tissues are associated with microvessel density following brain ischemia-reperfusion. Neurol Sci 2010 0.75
69 [Significant improvement of motor symptoms by deep brain stimulation of bilateral subthalamic nucleus in patients with moderate or advanced Parkinson's disease]. Zhonghua Yi Xue Za Zhi 2011 0.75
70 Optimising outcome assessment to improve quality and efficiency of stroke trials. Expert Rev Pharmacoecon Outcomes Res 2013 0.75
71 Segmented echo planar MR imaging of the brachial plexus with inversion recovery magnetization preparation at 3.0T. J Magn Reson Imaging 2008 0.75