Per-Olof Hasselgren

Author PubWeight™ 70.22‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 IKKbeta/NF-kappaB activation causes severe muscle wasting in mice. Cell 2004 6.25
2 Anatomical localization, gene expression profiling and functional characterization of adult human neck brown fat. Nat Med 2013 3.36
3 Preoperative evaluation of thyroid nodules with 18FDG-PET/CT. Surgery 2005 1.76
4 Colocalized granular cell tumor and infiltrating ductal carcinoma of the breast. Arch Pathol Lab Med 2002 1.62
5 Sepsis upregulates the gene expression of multiple ubiquitin ligases in skeletal muscle. Int J Biochem Cell Biol 2003 1.48
6 Dexamethasone and corticosterone induce similar, but not identical, muscle wasting responses in cultured L6 and C2C12 myotubes. J Cell Biochem 2008 1.31
7 Treatment of rats with calpain inhibitors prevents sepsis-induced muscle proteolysis independent of atrogin-1/MAFbx and MuRF1 expression. Am J Physiol Regul Integr Comp Physiol 2006 1.30
8 Synchronous parathyroid carcinoma, parathyroid adenoma, and papillary thyroid carcinoma in a patient with severe and long-standing hyperparathyroidism. Endocr Pract 2009 1.15
9 Calpain activity and muscle wasting in sepsis. Am J Physiol Endocrinol Metab 2008 1.14
10 Role of glucocorticoids in the molecular regulation of muscle wasting. Crit Care Med 2007 1.13
11 Superinduction of IL-6 by cycloheximide is associated with mRNA stabilization and sustained activation of p38 map kinase and NF-kappaB in cultured caco-2 cells. J Cell Biochem 2004 1.12
12 Expression and activity of C/EBPbeta and delta are upregulated by dexamethasone in skeletal muscle. J Cell Physiol 2005 1.11
13 Sepsis increases the expression and activity of the transcription factor Forkhead Box O 1 (FOXO1) in skeletal muscle by a glucocorticoid-dependent mechanism. Int J Biochem Cell Biol 2010 1.10
14 Resveratrol prevents dexamethasone-induced expression of the muscle atrophy-related ubiquitin ligases atrogin-1 and MuRF1 in cultured myotubes through a SIRT1-dependent mechanism. Biochem Biophys Res Commun 2011 1.08
15 Dexamethasone upregulates the expression of the nuclear cofactor p300 and its interaction with C/EBPbeta in cultured myotubes. J Cell Biochem 2005 1.07
16 C/EBP DNA-binding activity is upregulated by a glucocorticoid-dependent mechanism in septic muscle. Am J Physiol Regul Integr Comp Physiol 2002 1.05
17 Catabolic response to stress and potential benefits of nutrition support. Nutrition 2002 1.03
18 Sepsis stimulates calpain activity in skeletal muscle by decreasing calpastatin activity but does not activate caspase-3. Am J Physiol Regul Integr Comp Physiol 2004 1.02
19 Sepsis and glucocorticoids upregulate p300 and downregulate HDAC6 expression and activity in skeletal muscle. Am J Physiol Regul Integr Comp Physiol 2010 1.02
20 Mucosal and enterocyte IL-6 production during sepsis and endotoxemia--role of transcription factors and regulation by the stress response. Am J Surg 2002 1.01
21 Dexamethasone-induced protein degradation in cultured myotubes is p300/HAT dependent. Am J Physiol Regul Integr Comp Physiol 2006 0.99
22 GSK-3beta inhibitors reduce protein degradation in muscles from septic rats and in dexamethasone-treated myotubes. Int J Biochem Cell Biol 2005 0.99
23 IL-1beta stimulates IL-6 production in cultured skeletal muscle cells through activation of MAP kinase signaling pathway and NF-kappa B. Am J Physiol Regul Integr Comp Physiol 2003 0.98
24 Multiple transcription factors regulating the IL-6 gene are activated by cAMP in cultured Caco-2 cells. Am J Physiol Regul Integr Comp Physiol 2002 0.97
25 Expression and binding activity of the glucocorticoid receptor are upregulated in septic muscle. Am J Physiol Regul Integr Comp Physiol 2002 0.95
26 Protein breakdown in muscle from burned rats is blocked by insulin-like growth factor i and glycogen synthase kinase-3beta inhibitors. Endocrinology 2005 0.91
27 Early debridement for necrotizing pancreatitis: is it worthwhile? J Am Coll Surg 2002 0.91
28 Proteasome inhibitors induce heat shock response and increase IL-6 expression in human intestinal epithelial cells. Am J Physiol Regul Integr Comp Physiol 2002 0.90
29 Sepsis downregulates myostatin mRNA levels without altering myostatin protein levels in skeletal muscle. J Cell Biochem 2010 0.90
30 GSK-3beta activity is increased in skeletal muscle after burn injury in rats. Am J Physiol Regul Integr Comp Physiol 2007 0.89
31 Hyalinizing trabecular adenoma--an uncommon thyroid tumor frequently misdiagnosed as papillary or medullary thyroid carcinoma. Am J Surg 2007 0.89
32 Dexamethasone stimulates store-operated calcium entry and protein degradation in cultured L6 myotubes through a phospholipase A(2)-dependent mechanism. Am J Physiol Cell Physiol 2010 0.87
33 Multiple muscle wasting-related transcription factors are acetylated in dexamethasone-treated muscle cells. Biochem Cell Biol 2012 0.87
34 The NF-kappaB inhibitor curcumin blocks sepsis-induced muscle proteolysis. Mediators Inflamm 2008 0.87
35 PPARβ/δ regulates glucocorticoid- and sepsis-induced FOXO1 activation and muscle wasting. PLoS One 2013 0.86
36 Intestinal permeability and bacterial translocation are uncoupled after small bowel resection. J Pediatr Surg 2002 0.86
37 β-Hydroxy-β-methylbutyrate (HMB) prevents dexamethasone-induced myotube atrophy. Biochem Biophys Res Commun 2012 0.86
38 C/EBPβ regulates dexamethasone-induced muscle cell atrophy and expression of atrogin-1 and MuRF1. J Cell Biochem 2011 0.86
39 Expression of uncoupling protein 3 is upregulated in skeletal muscle during sepsis. Am J Physiol Endocrinol Metab 2003 0.86
40 Insulin-like growth factor-I inhibits dexamethasone-induced proteolysis in cultured L6 myotubes through PI3K/Akt/GSK-3beta and PI3K/Akt/mTOR-dependent mechanisms. Int J Biochem Cell Biol 2005 0.86
41 Probiotics potentiate IL-6 production in IL-1beta-treated Caco-2 cells through a heat shock-dependent mechanism. Am J Physiol Regul Integr Comp Physiol 2007 0.85
42 Transcription factors C/EBP-beta and -delta regulate IL-6 production in IL-1beta-stimulated human enterocytes. J Cell Physiol 2002 0.84
43 Proteasome inhibitors activate the transcription factors C/EBP-beta and delta in human intestinal epithelial cells. Biochem Biophys Res Commun 2002 0.84
44 Curcumin and muscle wasting: a new role for an old drug? Nutrition 2008 0.83
45 Dantrolene downregulates the gene expression and activity of the ubiquitin-proteasome proteolytic pathway in septic skeletal muscle. J Surg Res 2002 0.83
46 Suppression of atrogin-1 and MuRF1 prevents dexamethasone-induced atrophy of cultured myotubes. Metabolism 2013 0.83
47 Degradation of C/EBPbeta in cultured myotubes is calpain-dependent. J Cell Physiol 2006 0.82
48 Large parathyroid tumors have an increased risk of atypia and carcinoma. Am J Surg 2011 0.82
49 Interleukin-10 activates the transcription factor C/EBP and the interleukin-6 gene promoter in human intestinal epithelial cells. Surgery 2002 0.82
50 Sepsis and glucocorticoids downregulate the expression of the nuclear cofactor PGC-1beta in skeletal muscle. Am J Physiol Endocrinol Metab 2010 0.82
51 Acetylation and deacetylation--novel factors in muscle wasting. Metabolism 2012 0.82
52 Arsenite stabilizes IkappaBalpha and prevents NF-kappaB activation in IL-1 beta-stimulated Caco-2 cells independent of the heat shock response. J Cell Biochem 2002 0.81
53 Heat shock response reduces intestinal permeability in septic mice: potential role of interleukin-10. Am J Physiol Regul Integr Comp Physiol 2002 0.81
54 The stress response decreases NF-kappaB activation in liver of endotoxemic mice. Shock 2002 0.81
55 Insulin-like growth factor-I inhibits lysosomal and proteasome-dependent proteolysis in skeletal muscle after burn injury. J Burn Care Rehabil 2002 0.81
56 Treatment of cultured myotubes with the proteasome inhibitor beta-lactone increases the expression of the transcription factor C/EBPbeta. Am J Physiol Cell Physiol 2006 0.80
57 Insulin-like growth factor-I blocks dexamethasone-induced protein degradation in cultured myotubes by inhibiting multiple proteolytic pathways: 2002 ABA paper. J Burn Care Rehabil 2004 0.79
58 Hyperthermia-induced heat shock activates the transcription factor c/EBP-beta and augments IL-6 production in human intestinal epithelial cells. J Am Coll Surg 2002 0.79
59 Treatment of cultured myotubes with the calcium ionophore A23187 increases proteasome activity via a CaMK II-caspase-calpain-dependent mechanism. Surgery 2004 0.79
60 Molecules modulating gene transcription during muscle wasting in cancer, sepsis, and other critical illness. Crit Rev Clin Lab Sci 2011 0.79
61 Interleukin-6 induces thermotolerance in cultured Caco-2 cells independent of the heat shock response. Cytokine 2003 0.78
62 Calpain activity is increased in skeletal muscle from gastric cancer patients with no or minimal weight loss. Muscle Nerve 2011 0.78
63 CaMKII activity is reduced in skeletal muscle during sepsis. J Cell Biochem 2013 0.77
64 Experimental hyperthyroidism in rats increases the expression of the ubiquitin ligases atrogin-1 and MuRF1 and stimulates multiple proteolytic pathways in skeletal muscle. J Cell Biochem 2009 0.77
65 When initial postexcision PTH level does not fall appropriately during parathyroidectomy: what to do next? World J Surg 2009 0.76
66 Loss of muscle strength during sepsis is in part regulated by glucocorticoids and is associated with reduced muscle fiber stiffness. Am J Physiol Regul Integr Comp Physiol 2012 0.76
67 Comment on Sirtuin 1 in skeletal muscle of cachectic tumour-bearing rats. J Cachexia Sarcopenia Muscle 2012 0.75
68 Arsenite inhibits interleukin-6 production in human intestinal epithelial cells by down-regulating nuclear factor-kappaB activity. Clin Sci (Lond) 2002 0.75
69 Sodium arsenite downregulates transcriptional activity of AP-1 and CRE binding proteins in IL-1beta-treated Caco-2 cells by increasing the expression of the transcriptional repressor CREMalpha. J Cell Biochem 2003 0.75
70 The gene expression and activity of calpains and the muscle wasting-associated ubiquitin ligases, atrogin-1 and MuRF1, are not altered in patients with primary hyperparathyroidism. Int J Mol Med 2006 0.75