Published in Curr Opin Genet Dev on December 19, 2005
Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis. Mol Cell (2007) 14.58
Targeted deletion reveals essential and overlapping functions of the miR-17 through 92 family of miRNA clusters. Cell (2008) 12.29
A signature pattern of stress-responsive microRNAs that can evoke cardiac hypertrophy and heart failure. Proc Natl Acad Sci U S A (2006) 10.09
Dysregulation of microRNAs after myocardial infarction reveals a role of miR-29 in cardiac fibrosis. Proc Natl Acad Sci U S A (2008) 9.86
Redirection of silencing targets by adenosine-to-inosine editing of miRNAs. Science (2007) 7.15
Many novel mammalian microRNA candidates identified by extensive cloning and RAKE analysis. Genome Res (2006) 5.23
MicroRNAs: powerful new regulators of heart disease and provocative therapeutic targets. J Clin Invest (2007) 4.76
MicroRNAs are aberrantly expressed in hypertrophic heart: do they play a role in cardiac hypertrophy? Am J Pathol (2007) 4.65
Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation. Proc Natl Acad Sci U S A (2009) 3.76
Improved targeting of miRNA with antisense oligonucleotides. Nucleic Acids Res (2006) 3.43
RNA editing of the microRNA-151 precursor blocks cleavage by the Dicer-TRBP complex. EMBO Rep (2007) 3.40
Up-regulation of dicer, a component of the MicroRNA machinery, in prostate adenocarcinoma. Am J Pathol (2006) 3.30
MicroRNAs 221 and 222 bypass quiescence and compromise cell survival. Cancer Res (2008) 2.97
Induction of microRNA-221 by platelet-derived growth factor signaling is critical for modulation of vascular smooth muscle phenotype. J Biol Chem (2008) 2.81
MicroRNA: Biogenesis, Function and Role in Cancer. Curr Genomics (2010) 2.80
MicroRNA-155 is an Epstein-Barr virus-induced gene that modulates Epstein-Barr virus-regulated gene expression pathways. J Virol (2008) 2.45
Estradiol downregulates miR-21 expression and increases miR-21 target gene expression in MCF-7 breast cancer cells. Nucleic Acids Res (2009) 2.43
LncRNA loc285194 is a p53-regulated tumor suppressor. Nucleic Acids Res (2013) 2.38
Prognostic Values of microRNAs in Colorectal Cancer. Biomark Insights (2006) 2.35
miR-21 and miR-31 converge on TIAM1 to regulate migration and invasion of colon carcinoma cells. J Biol Chem (2010) 2.05
Small-molecule inhibitors of microrna miR-21 function. Angew Chem Int Ed Engl (2008) 2.00
Decreased expression of miR-125b and miR-100 in oral cancer cells contributes to malignancy. Genes Chromosomes Cancer (2009) 1.98
Human glioma growth is controlled by microRNA-10b. Cancer Res (2011) 1.96
Host-virus interaction: a new role for microRNAs. Retrovirology (2006) 1.88
Cancer stem cell-directed therapies: recent data from the laboratory and clinic. Mol Ther (2008) 1.83
RNA-based affinity purification reveals 7SK RNPs with distinct composition and regulation. RNA (2007) 1.77
MicroRNA-199b-5p impairs cancer stem cells through negative regulation of HES1 in medulloblastoma. PLoS One (2009) 1.73
Chromosomal rearrangements and microRNAs: a new cancer link with clinical implications. J Clin Invest (2007) 1.72
A novel microarray approach reveals new tissue-specific signatures of known and predicted mammalian microRNAs. Nucleic Acids Res (2007) 1.68
MicroRNAs, cancer and cancer stem cells. Cancer Lett (2010) 1.65
MicroRNA-145 targets YES and STAT1 in colon cancer cells. PLoS One (2010) 1.64
miR-489 is a tumour-suppressive miRNA target PTPN11 in hypopharyngeal squamous cell carcinoma (HSCC). Br J Cancer (2010) 1.61
The regulation of miRNA-211 expression and its role in melanoma cell invasiveness. PLoS One (2010) 1.55
Molecular dynamics simulations of RNA: an in silico single molecule approach. Biopolymers (2007) 1.41
MiR-24 tumor suppressor activity is regulated independent of p53 and through a target site polymorphism. PLoS One (2009) 1.40
MicroRNA reexpression as differentiation therapy in cancer. J Clin Invest (2009) 1.38
c-MYC-regulated miR-23a/24-2/27a cluster promotes mammary carcinoma cell invasion and hepatic metastasis by targeting Sprouty2. J Biol Chem (2013) 1.37
Loss of miR-204 expression enhances glioma migration and stem cell-like phenotype. Cancer Res (2012) 1.33
Systematic validation of predicted microRNAs for cyclin D1. BMC Cancer (2009) 1.32
Identification of rat lung-specific microRNAs by micoRNA microarray: valuable discoveries for the facilitation of lung research. BMC Genomics (2007) 1.27
Noncoding human Y RNAs are overexpressed in tumours and required for cell proliferation. Br J Cancer (2008) 1.21
Oncomirs: the potential role of non-coding microRNAs in understanding cancer. Bioinformation (2008) 1.21
SNPing cancer in the bud: microRNA and microRNA-target site polymorphisms as diagnostic and prognostic biomarkers in cancer. Pharmacol Ther (2012) 1.18
Genome wide copy number analysis of paediatric Burkitt lymphoma using formalin-fixed tissues reveals a subset with gain of chromosome 13q and corresponding miRNA over expression. Br J Haematol (2011) 1.12
Mechanisms coordinating ELAV/Hu mRNA regulons. Curr Opin Genet Dev (2013) 1.10
A Dynamic Search Process Underlies MicroRNA Targeting. Cell (2015) 1.09
Feud or Friend? The Role of the miR-17-92 Cluster in Tumorigenesis. Curr Genomics (2010) 1.09
Up-regulation of 91H promotes tumor metastasis and predicts poor prognosis for patients with colorectal cancer. PLoS One (2014) 1.08
Small molecule modifiers of the microRNA and RNA interference pathway. AAPS J (2009) 1.08
Expression profiling of difficult-to-diagnose thyroid histologic subtypes shows distinct expression profiles and identify candidate diagnostic microRNAs. Ann Surg Oncol (2011) 1.05
Lyn kinase-dependent regulation of miR181 and myeloid cell leukemia-1 expression: implications for drug resistance in myelogenous leukemia. Mol Pharmacol (2010) 1.04
MicroRNA-296 is enriched in cancer cells and downregulates p21WAF1 mRNA expression via interaction with its 3' untranslated region. Nucleic Acids Res (2011) 0.99
Dissecting the dynamics of dysregulation of cellular processes in mouse mammary gland tumor. BMC Genomics (2009) 0.99
microRNAs: tiny regulators of synapse function in development and disease. J Cell Mol Med (2008) 0.98
MicroRNA-196a is a putative diagnostic biomarker and therapeutic target for laryngeal cancer. PLoS One (2013) 0.98
MicroRNA-21 overexpression contributes to vestibular schwannoma cell proliferation and survival. Otol Neurotol (2010) 0.97
Overexpression of miR-196b and HOXA10 characterize a poor-prognosis gastric cancer subtype. World J Gastroenterol (2013) 0.96
MicroRNAs and cancer therapy: the next wave or here to stay? Cancer Biol Ther (2010) 0.95
β-adrenoceptor regulates miRNA expression in rat heart. Med Sci Monit (2012) 0.93
miR-708 promotes the development of bladder carcinoma via direct repression of Caspase-2. J Cancer Res Clin Oncol (2013) 0.92
MicroRNA: A matter of life or death. World J Biol Chem (2010) 0.91
The Akt-associated microRNAs. Cell Mol Life Sci (2012) 0.91
Polymer nanoparticles for drug and small silencing RNA delivery to treat cancers of different phenotypes. Wiley Interdiscip Rev Nanomed Nanobiotechnol (2013) 0.90
Stripping custom microRNA microarrays and the lessons learned about probe-slide interactions. Anal Biochem (2008) 0.90
The role of microRNAs and long non-coding RNAs in the pathology, diagnosis, and management of melanoma. Arch Biochem Biophys (2014) 0.89
High miR-449b expression in prostate cancer is associated with biochemical recurrence after radical prostatectomy. BMC Cancer (2014) 0.88
Genome-wide methylated CpG island profiles of melanoma cells reveal a melanoma coregulation network. Sci Rep (2013) 0.87
microRNAs as tumor inhibitors, oncogenes, biomarkers for drug efficacy and outcome predictors in lung cancer (review). Mol Med Rep (2012) 0.87
Serum miR-21 level: a potential diagnostic and prognostic biomarker for non-small cell lung cancer. Int J Clin Exp Med (2015) 0.87
Dual Action of miR-125b As a Tumor Suppressor and OncomiR-22 Promotes Prostate Cancer Tumorigenesis. PLoS One (2015) 0.85
MicroRNA-103 promotes colorectal cancer by targeting tumor suppressor DICER and PTEN. Int J Mol Sci (2014) 0.85
Reduction of miR-29c enhances pancreatic cancer cell migration and stem cell-like phenotype. Oncotarget (2015) 0.85
Structural and biochemical advances in mammalian RNAi. J Cell Biochem (2006) 0.85
MicroRNA profile in very young women with breast cancer. BMC Cancer (2014) 0.85
Parallel mRNA and microRNA profiling of HEV71-infected human neuroblastoma cells reveal the up-regulation of miR-1246 in association with DLG3 repression. PLoS One (2014) 0.83
miRNA expression in anaplastic thyroid carcinomas. PLoS One (2014) 0.83
A networks method for ranking microRNA dysregulation in cancer. BMC Syst Biol (2013) 0.82
The potential clinical applications and prospects of microRNAs in lung cancer. Onco Targets Ther (2014) 0.82
MicroRNA-145 inhibits migration and invasion by down-regulating FSCN1 in lung cancer. Int J Clin Exp Med (2015) 0.82
Involvement of microRNA families in cancer. Nucleic Acids Res (2012) 0.81
Inforna 2.0: A Platform for the Sequence-Based Design of Small Molecules Targeting Structured RNAs. ACS Chem Biol (2016) 0.81
Understanding cooperativity of microRNAs via microRNA association networks. BMC Genomics (2013) 0.81
MicroRNA 196B regulates FAS-mediated apoptosis in colorectal cancer cells. Oncotarget (2015) 0.80
DICER1 and PRKRA in Colon Adenocarcinoma. Biomark Insights (2008) 0.80
Rule discovery and distance separation to detect reliable miRNA biomarkers for the diagnosis of lung squamous cell carcinoma. BMC Genomics (2014) 0.80
microRNA-10b Is Overexpressed and Critical for Cell Survival and Proliferation in Medulloblastoma. PLoS One (2015) 0.80
Non-coding RNAs in the development and pathogenesis of eukaryotic microbes. Appl Microbiol Biotechnol (2013) 0.79
Micro-Ribonucleic Acid and Carcinogenesis: Breast Cancer as an Example. Oncol Rev (2015) 0.79
Targeted therapy in gastric cancer: personalizing cancer treatment based on patient genome. World J Gastroenterol (2014) 0.79
Clinical implication of long noncoding RNA 91H expression profile in osteosarcoma patients. Onco Targets Ther (2016) 0.78
Expression of microRNA-370 in human breast cancer compare with normal samples. Adv Biomed Res (2016) 0.77
Up-regulated microRNA499a by hepatitis B virus induced hepatocellular carcinogenesis via targeting MAPK6. PLoS One (2014) 0.77
The Role of MicroRNAs in Myeloproliferative Neoplasia. Int J Hematol Oncol Stem Cell Res (2016) 0.77
Dysregulated Serum MiRNA Profile and Promising Biomarkers in Dengue-infected Patients. Int J Med Sci (2016) 0.76
Promising Urinary Protein Biomarkers for the Early Detection of Hepatocellular Carcinoma among High-Risk Hepatitis C Virus Egyptian Patients. J Cancer (2012) 0.76
MicroRNA expression profiling of sputum for the detection of early and locally advanced non-small-cell lung cancer: a prospective case-control study. Curr Oncol (2016) 0.76
Important miRs of pathways in different tumor types. PLoS Comput Biol (2013) 0.76
MicroRNAs in Breast Cancer -Our Initial Results. Balkan J Med Genet (2012) 0.75
Specific microRNA-mRNA Regulatory Network of Colon Cancer Invasion Mediated by Tissue Kallikrein-Related Peptidase 6. Neoplasia (2017) 0.75
Gemcitabine and Antisense-microRNA Co-encapsulated PLGA-PEG Polymer Nanoparticles for Hepatocellular Carcinoma Therapy. ACS Appl Mater Interfaces (2016) 0.75
Dicing and slicing: the core machinery of the RNA interference pathway. FEBS Lett (2005) 4.63