Haihua Gu

Author PubWeight™ 25.97‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The 'Shp'ing news: SH2 domain-containing tyrosine phosphatases in cell signaling. Trends Biochem Sci 2003 6.24
2 Critical role for Gab2 in transformation by BCR/ABL. Cancer Cell 2002 2.42
3 A role for the scaffolding adapter GAB2 in breast cancer. Nat Med 2005 2.12
4 IgE-dependent activation of sphingosine kinases 1 and 2 and secretion of sphingosine 1-phosphate requires Fyn kinase and contributes to mast cell responses. J Biol Chem 2005 1.55
5 Activated STAT5 proteins induce activation of the PI 3-kinase/Akt and Ras/MAPK pathways via the Gab2 scaffolding adapter. Biochem J 2005 1.35
6 The scaffolding adapter Gab2, via Shp-2, regulates kit-evoked mast cell proliferation by activating the Rac/JNK pathway. J Biol Chem 2006 1.27
7 The docking protein Gab2 is overexpressed and estrogen regulated in human breast cancer. Oncogene 2002 1.26
8 Scaffolding adapter Grb2-associated binder 2 requires Syk to transmit signals from FcepsilonRI. J Immunol 2006 1.08
9 Protein-tyrosine phosphatase PTPN9 negatively regulates ErbB2 and epidermal growth factor receptor signaling in breast cancer cells. J Biol Chem 2010 1.05
10 Enhanced pulmonary arteriopathy in simian immunodeficiency virus-infected macaques exposed to morphine. Am J Respir Crit Care Med 2012 1.03
11 Hypoxia-inducible factor-1 α/platelet derived growth factor axis in HIV-associated pulmonary vascular remodeling. Respir Res 2011 1.03
12 Non-redundant roles of the Gab1 and Gab2 scaffolding adapters in VEGF-mediated signalling, migration, and survival of endothelial cells. Cell Signal 2009 1.03
13 p38 mitogen-activated protein kinase (MAPK) promotes cholesterol ester accumulation in macrophages through inhibition of macroautophagy. J Biol Chem 2012 0.96
14 Gab2 phosphorylation by RSK inhibits Shp2 recruitment and cell motility. Mol Cell Biol 2013 0.83
15 Lactation defect in a widely used MMTV-Cre transgenic line of mice. PLoS One 2011 0.82
16 Scaffolding protein Gab2 mediates fibroblast transformation by the SEA tyrosine kinase. Oncogene 2003 0.80
17 Leucine facilitates insulin signaling through a Gαi protein-dependent signaling pathway in hepatocytes. J Biol Chem 2013 0.78
18 Prolonged exposure to insulin induces mitochondrion-derived oxidative stress through increasing mitochondrial cholesterol content in hepatocytes. Endocrinology 2012 0.78
19 Pre-eclampsia outcomes in different hemodynamic models. J Obstet Gynaecol Res 2008 0.75