Microfluidic diffusive filter for apheresis (leukapheresis).

PubWeight™: 1.54‹?› | Rank: Top 4%

🔗 View Article (PMID 16372073)

Published in Lab Chip on November 11, 2005

Authors

Palaniappan Sethu1, Aaron Sin, Mehmet Toner

Author Affiliations

1: Surgical Services and Center for Engineering in Medicine, Massachusetts General Hospital, Harvard Medical School and Shriners Hospital for Children, MA 02114, Boston, USA. spalania@sbi.org

Articles citing this

Continuous inertial focusing, ordering, and separation of particles in microchannels. Proc Natl Acad Sci U S A (2007) 4.44

Label-free cell separation and sorting in microfluidic systems. Anal Bioanal Chem (2010) 2.60

Gravity-driven microfluidic particle sorting device with hydrodynamic separation amplification. Anal Chem (2007) 2.10

Cell Separation by Non-Inertial Force Fields in Microfluidic Systems. Mech Res Commun (2009) 1.24

Differential inertial focusing of particles in curved low-aspect-ratio microchannels. New J Phys (2009) 1.15

Microfluidic cell sorting: a review of the advances in the separation of cells from debulking to rare cell isolation. Lab Chip (2015) 1.09

Microfluidic blood cell sorting: now and beyond. Small (2014) 1.07

Stem cells in microfluidics. Biomicrofluidics (2011) 1.01

A pillar-based microfilter for isolation of white blood cells on elastomeric substrate. Biomicrofluidics (2013) 0.99

Curvature-induced dielectrophoresis for continuous separation of particles by charge in spiral microchannels. Biomicrofluidics (2011) 0.97

OPTIMIZATION OF A MICROFLUIDIC DEVICE FOR DIFFUSION-BASED EXTRACTION OF DMSO FROM A CELL SUSPENSION. Int J Heat Mass Transf (2008) 0.89

Biomimetic postcapillary expansions for enhancing rare blood cell separation on a microfluidic chip. Lab Chip (2011) 0.89

Affinity flow fractionation of cells via transient interactions with asymmetric molecular patterns. Sci Rep (2013) 0.87

Controlled incremental filtration: a simplified approach to design and fabrication of high-throughput microfluidic devices for selective enrichment of particles. Lab Chip (2014) 0.84

Characterization of a hybrid dielectrophoresis and immunocapture microfluidic system for cancer cell capture. Electrophoresis (2013) 0.82

Microfluidic technologies for synthetic biology. Int J Mol Sci (2011) 0.82

Enhancement of microfluidic particle separation using cross-flow filters with hydrodynamic focusing. Biomicrofluidics (2016) 0.82

New tools and new biology: recent miniaturized systems for molecular and cellular biology. Mol Cells (2013) 0.81

Effects of Aggregation on Blood Sedimentation and Conductivity. PLoS One (2015) 0.80

Dean flow-coupled inertial focusing in curved channels. Biomicrofluidics (2014) 0.79

A high-throughput microfluidic approach for 1000-fold leukocyte reduction of platelet-rich plasma. Sci Rep (2016) 0.79

Cellular enrichment through microfluidic fractionation based on cell biomechanical properties. Microfluid Nanofluidics (2015) 0.76

A scalable label-free approach to separate human pluripotent cells from differentiated derivatives. Biomicrofluidics (2016) 0.75

Separation of sperm and epithelial cells based on the hydrodynamic effect for forensic analysis. Biomicrofluidics (2015) 0.75

Simulation and experimental determination of the online separation of blood components with the help of microfluidic cascading spirals. Biomicrofluidics (2015) 0.75

Deformability based Cell Sorting using Microfluidic Ratchets Enabling Phenotypic Separation of Leukocytes Directly from Whole Blood. Sci Rep (2017) 0.75

Articles by these authors

Isolation of rare circulating tumour cells in cancer patients by microchip technology. Nature (2007) 19.33

Detection of mutations in EGFR in circulating lung-cancer cells. N Engl J Med (2008) 13.54

Circulating breast tumor cells exhibit dynamic changes in epithelial and mesenchymal composition. Science (2013) 10.87

Isolation of circulating tumor cells using a microvortex-generating herringbone-chip. Proc Natl Acad Sci U S A (2010) 7.77

Circulating tumor cells: approaches to isolation and characterization. J Cell Biol (2011) 6.54

Neutrophil chemotaxis in linear and complex gradients of interleukin-8 formed in a microfabricated device. Nat Biotechnol (2002) 5.37

Inertial focusing for tumor antigen-dependent and -independent sorting of rare circulating tumor cells. Sci Transl Med (2013) 4.74

Continuous inertial focusing, ordering, and separation of particles in microchannels. Proc Natl Acad Sci U S A (2007) 4.44

Isolation and characterization of circulating tumor cells from patients with localized and metastatic prostate cancer. Sci Transl Med (2010) 3.90

Application of genome-wide expression analysis to human health and disease. Proc Natl Acad Sci U S A (2005) 3.49

RNA sequencing of pancreatic circulating tumour cells implicates WNT signalling in metastasis. Nature (2012) 3.40

A microfluidic device for practical label-free CD4(+) T cell counting of HIV-infected subjects. Lab Chip (2006) 2.89

Androgen receptor signaling in circulating tumor cells as a marker of hormonally responsive prostate cancer. Cancer Discov (2012) 2.76

Effect of flow and surface conditions on human lymphocyte isolation using microfluidic chambers. Langmuir (2004) 2.76

Multifunctional encoded particles for high-throughput biomolecule analysis. Science (2007) 2.75

Engineering complex tissues. Tissue Eng (2006) 2.53

Controlled encapsulation of single-cells into monodisperse picolitre drops. Lab Chip (2008) 2.48

Rapid appearance of resolvin precursors in inflammatory exudates: novel mechanisms in resolution. J Immunol (2008) 2.32

Malaria-infected erythrocyte-derived microvesicles mediate cellular communication within the parasite population and with the host immune system. Cell Host Microbe (2013) 2.29

MYC regulation of a "poor-prognosis" metastatic cancer cell state. Proc Natl Acad Sci U S A (2010) 2.21

Overview of the Alliance for Cellular Signaling. Nature (2002) 2.15

Equilibrium separation and filtration of particles using differential inertial focusing. Anal Chem (2008) 2.13

Critical role for lysyl oxidase in mesenchymal stem cell-driven breast cancer malignancy. Proc Natl Acad Sci U S A (2012) 2.13

A microchip approach for practical label-free CD4+ T-cell counting of HIV-infected subjects in resource-poor settings. J Acquir Immune Defic Syndr (2007) 2.08

Clinical microfluidics for neutrophil genomics and proteomics. Nat Med (2010) 2.02

A high-throughput microfluidic real-time gene expression living cell array. Lab Chip (2006) 1.93

Asymmetry and aging of mycobacterial cells lead to variable growth and antibiotic susceptibility. Science (2011) 1.87

Microfluidic system for measuring neutrophil migratory responses to fast switches of chemical gradients. Lab Chip (2005) 1.86

Universal microfluidic gradient generator. Anal Chem (2006) 1.85

Spontaneous migration of cancer cells under conditions of mechanical confinement. Integr Biol (Camb) (2009) 1.81

A microfabrication-based dynamic array cytometer. Anal Chem (2002) 1.74

Cell detection and counting through cell lysate impedance spectroscopy in microfluidic devices. Lab Chip (2007) 1.63

Particle segregation and dynamics in confined flows. Phys Rev Lett (2009) 1.62

Continuous flow microfluidic device for rapid erythrocyte lysis. Anal Chem (2004) 1.61

Microfluidic isolation and transcriptome analysis of serum microvesicles. Lab Chip (2009) 1.61

Polar stimulation and constrained cell migration in microfluidic channels. Lab Chip (2007) 1.60

Particle focusing in staged inertial microfluidic devices for flow cytometry. Anal Chem (2010) 1.57

Spatially Invariant Vector Quantization: A pattern matching algorithm for multiple classes of image subject matter including pathology. J Pathol Inform (2011) 1.53

Liver-specific functional studies in a microfluidic array of primary mammalian hepatocytes. Anal Chem (2006) 1.53

Development of a microfabricated cytometry platform for characterization and sorting of individual leukocytes. Lab Chip (2004) 1.52

Dynamic gene expression profiling using a microfabricated living cell array. Anal Chem (2004) 1.50

LEA proteins during water stress: not just for plants anymore. Annu Rev Physiol (2011) 1.47

Burn injury reduces neutrophil directional migration speed in microfluidic devices. PLoS One (2010) 1.45

Cell handling using microstructured membranes. Lab Chip (2006) 1.40

'Living cantilever arrays' for characterization of mass of single live cells in fluids. Lab Chip (2008) 1.39

Microvortex for focusing, guiding and sorting of particles. Lab Chip (2008) 1.34

Analysis of factorial time-course microarrays with application to a clinical study of burn injury. Proc Natl Acad Sci U S A (2010) 1.33

The CTC-chip: an exciting new tool to detect circulating tumor cells in lung cancer patients. J Thorac Oncol (2009) 1.33

Enhancing the performance of a point-of-care CD4+ T-cell counting microchip through monocyte depletion for HIV/AIDS diagnostics. Lab Chip (2009) 1.28

Inertial focusing in microfluidics. Annu Rev Biomed Eng (2014) 1.27

Microfabrication-based modulation of embryonic stem cell differentiation. Lab Chip (2007) 1.27

Oxygen uptake rates and liver-specific functions of hepatocyte and 3T3 fibroblast co-cultures. Biotechnol Bioeng (2007) 1.24

Microfluidic flow-encoded switching for parallel control of dynamic cellular microenvironments. Lab Chip (2007) 1.23

Panning of multiple subsets of leukocytes on antibody-decorated poly(ethylene) glycol-coated glass slides. J Immunol Methods (2006) 1.20

Murine B16 melanomas expressing high levels of the chemokine stromal-derived factor-1/CXCL12 induce tumor-specific T cell chemorepulsion and escape from immune control. J Immunol (2006) 1.20

Mouse sperm desiccated and stored in trehalose medium without freezing. Biol Reprod (2005) 1.20

Biopolymer system for cell recovery from microfluidic cell capture devices. Anal Chem (2012) 1.20

Single-cell chemical lysis in picoliter-scale closed volumes using a microfabricated device. Anal Chem (2004) 1.20

Directional decisions during neutrophil chemotaxis inside bifurcating channels. Integr Biol (Camb) (2010) 1.20

Long-term storage of mouse spermatozoa after evaporative drying. Reproduction (2007) 1.19

Beneficial effect of microinjected trehalose on the cryosurvival of human oocytes. Fertil Steril (2002) 1.19

Development of a microscale cell culture analog to probe naphthalene toxicity. Biotechnol Prog (2004) 1.19

Magnetic barcode assay for genetic detection of pathogens. Nat Commun (2013) 1.18

Designing a hepatocellular microenvironment with protein microarraying and poly(ethylene glycol) photolithography. Langmuir (2004) 1.17

Epithelial cell guidance by self-generated EGF gradients. Integr Biol (Camb) (2012) 1.17

Mitochondrial localization and the persistent migration of epithelial cancer cells. Biophys J (2013) 1.16

A robust electrical microcytometer with 3-dimensional hydrofocusing. Lab Chip (2009) 1.15

Differential inertial focusing of particles in curved low-aspect-ratio microchannels. New J Phys (2009) 1.15

Successful cryopreservation of mouse oocytes by using low concentrations of trehalose and dimethylsulfoxide. Biol Reprod (2008) 1.14

Enrichment using antibody-coated microfluidic chambers in shear flow: model mixtures of human lymphocytes. Biotechnol Bioeng (2005) 1.13

Cryo-injury and biopreservation. Ann N Y Acad Sci (2005) 1.13

Elastomeric microchip electrospray emitter for stable cone-jet mode operation in the nanoflow regime. Anal Chem (2008) 1.13

Isothermal desiccation and vitrification kinetics of trehalose-dextran solutions. Langmuir (2004) 1.12

Microfluidic isolation of leukocytes from whole blood for phenotype and gene expression analysis. Anal Chem (2006) 1.11

Inertial focusing dynamics in spiral microchannels. Phys Fluids (1994) (2012) 1.11

A bioartificial liver device secreting interleukin-1 receptor antagonist for the treatment of hepatic failure in rats. J Surg Res (2006) 1.08

A microfabricated electrical differential counter for the selective enumeration of CD4+ T lymphocytes. Lab Chip (2011) 1.08

Desiccation kinetics of biopreservation solutions in microchannels. J Appl Phys (2006) 1.07

Squishy non-spherical hydrogel microparticles. Macromol Rapid Commun (2009) 1.07

Neutrophil migration assay from a drop of blood. Lab Chip (2008) 1.07

Concentration and purification of human immunodeficiency virus type 1 virions by microfluidic separation of superparamagnetic nanoparticles. Anal Chem (2010) 1.06

Specific pathogen detection using bioorthogonal chemistry and diagnostic magnetic resonance. Bioconjug Chem (2011) 1.06

Computer aided diagnostic tools aim to empower rather than replace pathologists: Lessons learned from computational chess. J Pathol Inform (2011) 1.06

Desiccation tolerance of spermatozoa dried at ambient temperature: production of fetal mice. Biol Reprod (2002) 1.05

Microfabricated grooved substrates as platforms for bioartificial liver reactors. Biotechnol Bioeng (2005) 1.05

Hepatic tissue engineering for adjunct and temporary liver support: critical technologies. Liver Transpl (2004) 1.04

Cryopreservation of isolated primary rat hepatocytes: enhanced survival and long-term hepatospecific function. Ann Surg (2005) 1.03

A spin-drying technique for lyopreservation of mammalian cells. Ann Biomed Eng (2011) 1.02

Vitrification by ultra-fast cooling at a low concentration of cryoprotectants in a quartz micro-capillary: a study using murine embryonic stem cells. Cryobiology (2008) 1.02

Surface topography induces 3D self-orientation of cells and extracellular matrix resulting in improved tissue function. Integr Biol (Camb) (2009) 1.02

Polyelectrolyte nano-scaffolds for the design of layered cellular architectures. Tissue Eng (2006) 1.00

Microfluidics-based capture of human neutrophils for expression analysis in blood and bronchoalveolar lavage. Lab Invest (2011) 1.00

Metabolic restructuring during energy-limited states: insights from Artemia franciscana embryos and other animals. J Insect Physiol (2011) 1.00

Quantitative microinjection of trehalose into mouse oocytes and zygotes, and its effect on development. Cryobiology (2003) 1.00

Cryopreservation of fetal skin is improved by extracellular trehalose. Cryobiology (2002) 0.99

Microfluidic leukocyte isolation for gene expression analysis in critically ill hospitalized patients. Clin Chem (2008) 0.99

Bioengineering of liver assist devices. J Hepatobiliary Pancreat Surg (2002) 0.98

Patterned co-culture of primary hepatocytes and fibroblasts using polyelectrolyte multilayer templates. Macromol Biosci (2007) 0.97