Published in Trends Cell Biol on January 06, 2006
Mechanotransduction at a distance: mechanically coupling the extracellular matrix with the nucleus. Nat Rev Mol Cell Biol (2009) 5.41
"Laminopathies": a wide spectrum of human diseases. Exp Cell Res (2007) 3.46
A perinuclear actin cap regulates nuclear shape. Proc Natl Acad Sci U S A (2009) 3.12
Interactions between nuclei and the cytoskeleton are mediated by SUN-KASH nuclear-envelope bridges. Annu Rev Cell Dev Biol (2010) 3.04
Laminopathies and the long strange trip from basic cell biology to therapy. J Clin Invest (2009) 2.94
LINC complexes form by binding of three KASH peptides to domain interfaces of trimeric SUN proteins. Cell (2012) 2.79
Distinct structural and mechanical properties of the nuclear lamina in Hutchinson-Gilford progeria syndrome. Proc Natl Acad Sci U S A (2006) 2.53
Reshaping of the endoplasmic reticulum limits the rate for nuclear envelope formation. J Cell Biol (2008) 2.19
A nuclear-envelope bridge positions nuclei and moves chromosomes. J Cell Sci (2009) 2.10
SUN1 and SUN2 play critical but partially redundant roles in anchoring nuclei in skeletal muscle cells in mice. Proc Natl Acad Sci U S A (2009) 2.07
Dysfunctional connections between the nucleus and the actin and microtubule networks in laminopathic models. Biophys J (2008) 1.92
Functional association of Sun1 with nuclear pore complexes. J Cell Biol (2007) 1.81
TorsinA binds the KASH domain of nesprins and participates in linkage between nuclear envelope and cytoskeleton. J Cell Sci (2008) 1.80
Dynamics and molecular interactions of linker of nucleoskeleton and cytoskeleton (LINC) complex proteins. J Cell Sci (2009) 1.74
Mutant torsinA interferes with protein processing through the secretory pathway in DYT1 dystonia cells. Proc Natl Acad Sci U S A (2007) 1.73
Telomere anchoring at the nuclear periphery requires the budding yeast Sad1-UNC-84 domain protein Mps3. J Cell Biol (2007) 1.67
Transmembrane protein Sun2 is involved in tethering mammalian meiotic telomeres to the nuclear envelope. Proc Natl Acad Sci U S A (2007) 1.63
Lamin A variants that cause striated muscle disease are defective in anchoring transmembrane actin-associated nuclear lines for nuclear movement. Proc Natl Acad Sci U S A (2010) 1.61
Primary dystonia: molecules and mechanisms. Nat Rev Neurol (2009) 1.51
LULL1 retargets TorsinA to the nuclear envelope revealing an activity that is impaired by the DYT1 dystonia mutation. Mol Biol Cell (2009) 1.47
Actomyosin tension exerted on the nucleus through nesprin-1 connections influences endothelial cell adhesion, migration, and cyclic strain-induced reorientation. Biophys J (2010) 1.43
Mechanical properties of the cell nucleus and the effect of emerin deficiency. Biophys J (2006) 1.40
Nuclear migration during retinal development. Brain Res (2007) 1.38
LINC complexes in health and disease. Nucleus (2011) 1.37
Dynein drives nuclear rotation during forward progression of motile fibroblasts. J Cell Sci (2008) 1.37
Lamin A/C-mediated neuromuscular junction defects in Emery-Dreifuss muscular dystrophy. J Cell Biol (2009) 1.36
Herpes simplex virus infection induces phosphorylation and delocalization of emerin, a key inner nuclear membrane protein. J Virol (2007) 1.28
Communication between the cytoskeleton and the nuclear envelope to position the nucleus. Mol Biosyst (2007) 1.28
Nuclear envelope transmembrane proteins (NETs) that are up-regulated during myogenesis. BMC Cell Biol (2006) 1.26
What drives cell morphogenesis: a look inside the vertebrate photoreceptor. Dev Dyn (2009) 1.21
Nesprins, but not sun proteins, switch isoforms at the nuclear envelope during muscle development. Dev Dyn (2010) 1.13
Inner nuclear envelope proteins SUN1 and SUN2 play a prominent role in the DNA damage response. Curr Biol (2012) 1.05
The effects of osmotic stress on the structure and function of the cell nucleus. J Cell Biochem (2010) 1.03
SUN proteins facilitate the removal of membranes from chromatin during nuclear envelope breakdown. J Cell Biol (2014) 1.00
Emerging common molecular pathways for primary dystonia. Mov Disord (2013) 1.00
Direct force probe reveals the mechanics of nuclear homeostasis in the mammalian cell. Proc Natl Acad Sci U S A (2015) 1.00
Centrosome attachment to the C. elegans male pronucleus is dependent on the surface area of the nuclear envelope. Dev Biol (2009) 0.98
SMRT analysis of MTOC and nuclear positioning reveals the role of EB1 and LIC1 in single-cell polarization. J Cell Sci (2011) 0.96
Forebrain deletion of the dystonia protein torsinA causes dystonic-like movements and loss of striatal cholinergic neurons. Elife (2015) 0.94
Plant SUN domain proteins: components of putative plant LINC complexes? Plant Signal Behav (2010) 0.88
Inherited isolated dystonia: clinical genetics and gene function. Neurotherapeutics (2014) 0.88
Untethering the nuclear envelope and cytoskeleton: biologically distinct dystonias arising from a common cellular dysfunction. Int J Cell Biol (2012) 0.87
Increased expression of Syne1/nesprin-1 facilitates nuclear envelope structure changes in embryonic stem cell differentiation. Dev Dyn (2011) 0.86
Mechanics of the nucleus. Compr Physiol (2011) 0.85
Experimental techniques for study of chromatin mechanics in intact nuclei and living cells. Chromosome Res (2008) 0.85
Actin: its cumbersome pilgrimage through cellular compartments. Histochem Cell Biol (2008) 0.84
The nuclear envelope in the plant cell cycle: structure, function and regulation. Ann Bot (2011) 0.82
Focal adhesion-chromatin linkage controls tumor cell resistance to radio- and chemotherapy. Chemother Res Pract (2012) 0.82
The luminal N-terminus of yeast Nvj1 is an inner nuclear membrane anchor. Traffic (2008) 0.79
Focal adhesion kinase knockdown modulates the response of human corneal epithelial cells to topographic cues. Acta Biomater (2012) 0.78
Nucleocytoplasmic connections and deafness. J Clin Invest (2013) 0.76
UNcleProt (Universal Nuclear Protein database of barley): the first nuclear protein database that distinguishes proteins from different phases of the cell cycle. Nucleus (2016) 0.75
Epigenetic repression of ribosomal RNA transcription by ROCK-dependent aberrant cytoskeletal organization. Sci Rep (2016) 0.75
Microtubule-induced focal adhesion disassembly is mediated by dynamin and focal adhesion kinase. Nat Cell Biol (2005) 4.99
Nuclear movement regulated by Cdc42, MRCK, myosin, and actin flow establishes MTOC polarization in migrating cells. Cell (2005) 4.86
EB1 and APC bind to mDia to stabilize microtubules downstream of Rho and promote cell migration. Nat Cell Biol (2004) 4.55
Localized stabilization of microtubules by integrin- and FAK-facilitated Rho signaling. Science (2004) 3.93
Linear arrays of nuclear envelope proteins harness retrograde actin flow for nuclear movement. Science (2010) 3.53
Beyond polymer polarity: how the cytoskeleton builds a polarized cell. Nat Rev Mol Cell Biol (2008) 2.53
Generation of noncentrosomal microtubule arrays. J Cell Sci (2006) 2.51
Clathrin mediates integrin endocytosis for focal adhesion disassembly in migrating cells. J Cell Biol (2009) 2.28
A role for cytoplasmic dynein and LIS1 in directed cell movement. J Cell Biol (2003) 2.23
Cell biology: Tubulin acetylation and cell motility. Nature (2003) 2.10
The formin mDia2 stabilizes microtubules independently of its actin nucleation activity. J Cell Biol (2008) 1.96
Par3 and dynein associate to regulate local microtubule dynamics and centrosome orientation during migration. Curr Biol (2009) 1.93
Linking axonal degeneration to microtubule remodeling by Spastin-mediated microtubule severing. J Cell Biol (2005) 1.80
Dynamics and molecular interactions of linker of nucleoskeleton and cytoskeleton (LINC) complex proteins. J Cell Sci (2009) 1.74
Moesin regulates stable microtubule formation and limits retroviral infection in cultured cells. EMBO J (2006) 1.64
Lamin A variants that cause striated muscle disease are defective in anchoring transmembrane actin-associated nuclear lines for nuclear movement. Proc Natl Acad Sci U S A (2010) 1.61
Adenomatous polyposis coli protein nucleates actin assembly and synergizes with the formin mDia1. J Cell Biol (2010) 1.59
The formin mDia regulates GSK3beta through novel PKCs to promote microtubule stabilization but not MTOC reorientation in migrating fibroblasts. Mol Biol Cell (2006) 1.53
Export from pericentriolar endocytic recycling compartment to cell surface depends on stable, detyrosinated (glu) microtubules and kinesin. Mol Biol Cell (2002) 1.52
Regulated binding of adenomatous polyposis coli protein to actin. J Biol Chem (2007) 1.41
HIV-1 induces the formation of stable microtubules to enhance early infection. Cell Host Microbe (2013) 1.34
Orientation and function of the nuclear-centrosomal axis during cell migration. Curr Opin Cell Biol (2011) 1.32
TAN lines: a novel nuclear envelope structure involved in nuclear positioning. Nucleus (2011) 1.20
Microtubule plus-end binding protein EB1 is necessary for muscle cell differentiation, elongation and fusion. J Cell Sci (2009) 1.17
Src SH2 arginine 175 is required for cell motility: specific focal adhesion kinase targeting and focal adhesion assembly function. Mol Cell Biol (2006) 1.11
Induction of apoptosis by the garlic-derived compound S-allylmercaptocysteine (SAMC) is associated with microtubule depolymerization and c-Jun NH(2)-terminal kinase 1 activation. Cancer Res (2003) 1.10
Aquaporin 2 promotes cell migration and epithelial morphogenesis. J Am Soc Nephrol (2012) 1.05
Microtubule-actin cross-talk at focal adhesions. Sci STKE (2002) 1.05
Real-time centrosome reorientation during fibroblast migration. Methods Enzymol (2006) 1.01
Actin-capping protein promotes microtubule stability by antagonizing the actin activity of mDia1. Mol Biol Cell (2012) 1.01
INF2 promotes the formation of detyrosinated microtubules necessary for centrosome reorientation in T cells. J Cell Biol (2012) 1.01
Emerin organizes actin flow for nuclear movement and centrosome orientation in migrating fibroblasts. Mol Biol Cell (2013) 0.98
Blocking farnesylation of the prelamin A variant in Hutchinson-Gilford progeria syndrome alters the distribution of A-type lamins. Nucleus (2012) 0.90
Effects of a series of organosulfur compounds on mitotic arrest and induction of apoptosis in colon cancer cells. Mol Cancer Ther (2005) 0.89
CLASP2 interacts with p120-catenin and governs microtubule dynamics at adherens junctions. J Cell Biol (2013) 0.86
Plus-end tracking proteins, CLASPs, and a viral Akt mimic regulate herpesvirus-induced stable microtubule formation and virus spread. Proc Natl Acad Sci U S A (2013) 0.86
Linker of nucleoskeleton and cytoskeleton (LINC) complex-mediated actin-dependent nuclear positioning orients centrosomes in migrating myoblasts. Nucleus (2015) 0.85
The sulindac derivatives OSI-461, OSIP486823, and OSIP487703 arrest colon cancer cells in mitosis by causing microtubule depolymerization. Mol Cancer Ther (2006) 0.82
CP248, a derivative of exisulind, causes growth inhibition, mitotic arrest, and abnormalities in microtubule polymerization in glioma cells. Mol Cancer Ther (2002) 0.81
HDAC6-pack: cortactin acetylation joins the brew. Dev Cell (2007) 0.78
Reinforcing the LINC complex connection to actin filaments: the role of FHOD1 in TAN line formation and nuclear movement. Cell Cycle (2015) 0.78