Published in Eur J Clin Pharmacol on January 12, 2006
Polypharmacy as commonly defined is an indicator of limited value in the assessment of drug-related problems. Br J Clin Pharmacol (2006) 2.57
Increasing polypharmacy - an individual-based study of the Swedish population 2005-2008. BMC Clin Pharmacol (2010) 2.04
Cardiovascular medication burden in dementia disorders: a nationwide study of 19,743 dementia patients in the Swedish Dementia Registry. Alzheimers Res Ther (2014) 1.57
Do newly marketed generic medicines expand markets using descriptive time series analysis and mixed logit models? Korea as an exemplar and its implications. BMC Health Serv Res (2016) 1.41
Cardiovascular drug therapy in the elderly: benefits and challenges. Nat Rev Cardiol (2010) 1.13
Potential therapeutic competition in community-living older adults in the U.S.: use of medications that may adversely affect a coexisting condition. PLoS One (2014) 1.08
Validating the Johns Hopkins ACG Case-Mix System of the elderly in Swedish primary health care. BMC Public Health (2006) 1.07
Adverse drug effects in elderly people -- a disparity between clinical examination and adverse effects self-reported by the patient. Eur J Clin Pharmacol (2007) 0.99
Influence of mandatory generic substitution on pharmaceutical sales patterns: a national study over five years. BMC Health Serv Res (2008) 0.99
Enhanced medication management services in the community: A win-win proposal from an economic, clinical and humanistic perspective. Can Pharm J (Ott) (2013) 0.95
Polypharmacy and risk of antiretroviral drug interactions among the aging HIV-infected population. J Gen Intern Med (2013) 0.92
National indicators for quality of drug therapy in older persons: the Swedish experience from the first 10 years. Drugs Aging (2015) 0.92
Trends in inappropriate drug therapy prescription in the elderly in Sweden from 2006 to 2013: assessment using national indicators. Drugs Aging (2014) 0.91
The prevalence of potential alcohol-drug interactions in older adults. Scand J Prim Health Care (2013) 0.90
Potentially severe drug-drug interactions among older people and associations in assisted living facilities in Finland: a cross-sectional study. Scand J Prim Health Care (2016) 0.85
Prevalence and predictors of polypharmacy among Korean elderly. PLoS One (2014) 0.82
Polypharmacy in the terminal stage of cancer. Support Care Cancer (2015) 0.82
Health and social service use among old people in the last 2 years of life. Eur J Ageing (2007) 0.82
Characteristics and drug utilization patterns for heavy users of prescription drugs among the elderly: a Danish register-based drug utilization study. Eur J Clin Pharmacol (2015) 0.81
Continuing education course to attain collaborative comprehensive medication review competencies. Am J Pharm Educ (2009) 0.80
Risk Factors for Malnutrition in Older Adults: A Systematic Review of the Literature Based on Longitudinal Data. Adv Nutr (2016) 0.80
The association between use of cardiovascular drugs and antidepressants: a nationwide register-based study. Eur J Clin Pharmacol (2008) 0.79
Melatonin for sedative withdrawal in older patients with primary insomnia: a randomized double-blind placebo-controlled trial. Br J Clin Pharmacol (2014) 0.78
Influence of urban residence on use of psychotropic medications in Pennsylvania, USA: cross-sectional comparison of older adults attending senior centers. Drugs Aging (2014) 0.78
Impact of missing data mechanism on the estimate of change: a case study on cognitive function and polypharmacy among older persons. Clin Epidemiol (2015) 0.77
The impact of dementia on drug costs in older people: results from the SNAC study. BMC Neurol (2016) 0.75
Sufficient competence in community elderly care? Results from a competence measurement of nursing staff. BMC Nurs (2016) 0.75
Changes in Drug Use and Polypharmacy After the Age of 90: A Longitudinal Study of the Danish 1905 Cohort. J Am Geriatr Soc (2016) 0.75
Drug utilization patterns among elderly hospitalized patients on poly-pharmacy in Punjab, Pakistan. J Pharm Policy Pract (2017) 0.75
Social Pharmacy and Clinical Pharmacy-Joining Forces. Pharmacy (Basel) (2015) 0.75
Updating the Beers criteria for potentially inappropriate medication use in older adults: results of a US consensus panel of experts. Arch Intern Med (2003) 13.47
Recent patterns of medication use in the ambulatory adult population of the United States: the Slone survey. JAMA (2002) 10.03
Potentially inappropriate medication use in the community-dwelling elderly: findings from the 1996 Medical Expenditure Panel Survey. JAMA (2001) 4.78
Potentially inappropriate medication use among elderly home care patients in Europe. JAMA (2005) 3.13
Inappropriate drug prescribing in home-dwelling, elderly patients: a population-based survey. Arch Intern Med (2002) 2.56
Drug therapy in the elderly: what doctors believe and patients actually do. Br J Clin Pharmacol (2001) 2.15
Use of medications and polypharmacy are increasing among the elderly. J Clin Epidemiol (2002) 2.10
Inappropriate medication prescribing for elderly ambulatory care patients. Arch Intern Med (2004) 1.91
The consumption of drugs by 75-year-old individuals living in their own homes. Eur J Clin Pharmacol (2000) 1.79
Use of medications by persons 65 and over: data from the established populations for epidemiologic studies of the elderly. J Gerontol (1992) 1.78
Prescription drug use, diagnoses, and healthcare utilization among the elderly. Ann Pharmacother (2001) 1.76
The development of polypharmacy. A longitudinal study. Fam Pract (2000) 1.67
Potentially inappropriate medication use in community residential care facilities. Ann Pharmacother (2003) 1.45
Self-reported medication use for older people in England and Wales. J Clin Pharm Ther (2001) 1.37
Potentially inappropriate medication use by elderly persons in U.S. Health Maintenance Organizations, 2000-2001. J Am Geriatr Soc (2005) 1.22
Geriatric drug therapy and healthcare utilization in the United kingdom. Ann Pharmacother (2002) 1.15
Changes in drug treatment in the elderly between 1971 and 2000. Eur J Clin Pharmacol (2003) 1.15
Use of prescription medications in an elderly rural population: the MoVIES Project. Ann Pharmacother (1996) 1.13
Adverse drug reactions and polypharmacy in the elderly in general practice. Eur J Clin Pharmacol (1999) 1.13
Ten-year change in the use of medical drugs among the elderly--a longitudinal study and cohort comparison. J Clin Epidemiol (1994) 1.08
Self-reported medication non-compliance in the elderly. Eur J Clin Pharmacol (1997) 1.06
Psychotropics among the home-dwelling elderly--increasing trends. Int J Geriatr Psychiatry (2002) 0.96
Factors predicting change in prescription and nonprescription drug use in a community-residing black and white elderly population. J Clin Epidemiol (1996) 0.95
Polypharmacy among older men in South Wales. Eur J Clin Pharmacol (1999) 0.91
A longitudinal evaluation of drug use in an ambulatory elderly population. J Clin Epidemiol (1991) 0.88
Sedative drug use in the home-dwelling elderly. Ann Pharmacother (2004) 0.85
Use of psychotropics among home-dwelling nondemented and demented elderly. Int J Geriatr Psychiatry (2003) 0.82
Use of drugs by non-institutionalized urban Finns born in 1904-1923 and the association of drug use with mood and self-rated health. Age Ageing (1992) 0.78
Increase in drug use after admission to Dutch nursing homes. Pharm World Sci (2003) 0.75
Relationships between prescription and non-prescription drug use in an elderly population. Arch Gerontol Geriatr (2004) 0.75
The use of prescription drugs among elderly Finnish men. J Clin Pharm Ther (1990) 0.75
A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD. Neuron (2011) 18.73
Chromosome 9p21 in amyotrophic lateral sclerosis in Finland: a genome-wide association study. Lancet Neurol (2010) 4.19
Delirium is a strong risk factor for dementia in the oldest-old: a population-based cohort study. Brain (2012) 2.64
Association between blood pressure and survival over 9 years in a general population aged 85 and older. J Am Geriatr Soc (2006) 2.21
Use of medications and polypharmacy are increasing among the elderly. J Clin Epidemiol (2002) 2.10
Self-reported sleep duration and cognitive functioning in the general population. J Sleep Res (2009) 1.71
Education, the brain and dementia: neuroprotection or compensation? Brain (2010) 1.68
Effects of dementia on perceived daily pain in home-dwelling elderly people: a population-based study. Age Ageing (2004) 1.56
Incidence of stroke in people with Alzheimer disease: a national register-based approach. Neurology (2013) 1.55
Factors related to poor control of blood pressure with antihypertensive drug therapy. Blood Press (2003) 1.53
Anticholinergic drug use, serum anticholinergic activity, and adverse drug events among older people: a population-based study. Drugs Aging (2013) 1.53
Increased incidence of hip fractures. A population based-study in Finland. Bone (2006) 1.50
Association of polypharmacy with nutritional status, functional ability and cognitive capacity over a three-year period in an elderly population. Pharmacoepidemiol Drug Saf (2011) 1.47
Polypharmacy status as an indicator of mortality in an elderly population. Drugs Aging (2009) 1.45
Patterns of drug use and factors associated with polypharmacy and excessive polypharmacy in elderly persons: results of the Kuopio 75+ study: a cross-sectional analysis. Drugs Aging (2009) 1.31
Senile systemic amyloidosis affects 25% of the very aged and associates with genetic variation in alpha2-macroglobulin and tau: a population-based autopsy study. Ann Med (2008) 1.30
Self-reported use of anti-malarial drugs and health facility management of malaria in Ghana. Malar J (2007) 1.29
Do pictograms improve children's understanding of medicine leaflet information? Patient Educ Couns (2004) 1.27
Intensive geriatric rehabilitation of hip fracture patients: a randomized, controlled trial. Acta Orthop Scand (2002) 1.19
Neuropsychiatric symptoms and quality of life in patients with very mild and mild Alzheimer's disease. Int J Geriatr Psychiatry (2010) 1.13
B-type natriuretic peptide as a predictor of declining cognitive function and dementia--a cohort study of an elderly general population with a 5-year follow-up. Ann Med (2010) 1.09
Use of existing data sources in clinical epidemiology: Finnish health care registers in Alzheimer's disease research - the Medication use among persons with Alzheimer's disease (MEDALZ-2005) study. Clin Epidemiol (2013) 1.09
Amyloid precursor protein (APP) A673T mutation in the elderly Finnish population. Neurobiol Aging (2012) 1.07
Combined hearing and visual impairment and depression in a population aged 75 years and older. Int J Geriatr Psychiatry (2002) 1.06
Validity of the Finnish Prescription Register for measuring psychotropic drug exposures among elderly finns: a population-based intervention study. Drugs Aging (2010) 1.05
Concomitant use of analgesics and psychotropics in home-dwelling elderly people-Kuopio 75 + study. Br J Clin Pharmacol (2005) 1.04
The non-use of hearing aids in people aged 75 years and over in the city of Kuopio in Finland. Eur Arch Otorhinolaryngol (2004) 1.03
Atrial fibrillation, stroke, and cognition: a longitudinal population-based study of people aged 85 and older. Stroke (2007) 1.02
A randomized controlled trial of rehabilitation after hospitalization in frail older women: effects on strength, balance and mobility. Scand J Med Sci Sports (2002) 1.01
Community prevalence of alcohol use and concomitant use of medication--a source of possible risk in the elderly aged 75 and older? Int J Geriatr Psychiatry (2005) 1.00
Adverse drug effects in elderly people -- a disparity between clinical examination and adverse effects self-reported by the patient. Eur J Clin Pharmacol (2007) 0.99
Drug Burden Index associated with function in community-dwelling older people in Finland: a cross-sectional study. Ann Med (2011) 0.99
Serum total cholesterol levels and all-cause mortality in a home-dwelling elderly population: a six-year follow-up. Scand J Prim Health Care (2010) 0.96
Use of psychotropics is high among very old people. Eur J Clin Pharmacol (2003) 0.96
Impact of restricted reimbursement on the use of statins in Finland: a register-based study. Med Care (2010) 0.95
Contribution of musculoskeletal pain to postural balance in community-dwelling people aged 75 years and older. J Gerontol A Biol Sci Med Sci (2010) 0.94
Antidementia drug use among community-dwelling individuals with Alzheimer's disease in Finland: a nationwide register-based study. Int Clin Psychopharmacol (2014) 0.94
Chromosome 21 BACE2 haplotype associates with Alzheimer's disease: a two-stage study. J Neurol Sci (2005) 0.93
Vascular risk factors and dementia in the general population aged >85 years: prospective population-based study. Neurobiol Aging (2008) 0.93
Dementia and oral health among subjects aged 75 years or older. Gerodontology (2010) 0.93
Neuropathologic findings of dementia with lewy bodies (DLB) in a population-based Vantaa 85+ study. J Alzheimers Dis (2009) 0.93
Visual assessment of [(11)C]PIB PET in patients with cognitive impairment. Eur J Nucl Med Mol Imaging (2010) 0.93
Analgesic use among community-dwelling people aged 75 years and older: A population-based interview study. Am J Geriatr Pharmacother (2010) 0.92
ApoE epsilon3-haplotype modulates Alzheimer beta-amyloid deposition in the brain. Am J Med Genet (2002) 0.91
Effects of a group-based exercise program on functional abilities in frail older women after hospital discharge. Aging Clin Exp Res (2006) 0.91
Multiple information sources and consequences of conflicting information about medicine use during pregnancy: a multinational Internet-based survey. J Med Internet Res (2014) 0.91
Risk of death among persons with Alzheimer's disease: a national register-based nested case-control study. J Alzheimers Dis (2013) 0.91
Association between frailty and dementia: a population-based study. Gerontology (2013) 0.90
Plasma homocysteine, Alzheimer and cerebrovascular pathology: a population-based autopsy study. Brain (2013) 0.89
Intracerebral hemorrhage in the oldest old: a population-based study (vantaa 85+). Front Neurol (2012) 0.89
Physical activity at age of 20-64 years and mobility and muscle strength in old age: a community-based study. J Gerontol A Biol Sci Med Sci (2012) 0.89
Incident hip fractures among community dwelling persons with Alzheimer's disease in a Finnish nationwide register-based cohort. PLoS One (2013) 0.88
Achievements and shortcomings of Finnish asthma care. Scand J Public Health (2004) 0.88
Use of strong opioids among community-dwelling persons with and without Alzheimer's disease in Finland. Pain (2011) 0.88
Neurofibrillary tau pathology modulated by genetic variation of alpha-synuclein. Ann Neurol (2008) 0.88
Psychotropic drug use in community-dwelling elderly people-characteristics of persistent and incident users. Eur J Clin Pharmacol (2011) 0.87
High prevalence of psychotropic drug use among persons with and without Alzheimer's disease in Finnish nationwide cohort. Eur Neuropsychopharmacol (2014) 0.87
Salivary albumin and other constituents and their relation to oral and general health in the elderly. Oral Surg Oral Med Oral Pathol Oral Radiol Endod (2002) 0.87
Changes in alcohol consumption and drinking patterns during 11 years of follow-up among ageing men: the FinDrink study. Eur J Public Health (2009) 0.86
Frailty as a predictor of all-cause mortality in older men and women. Geriatr Gerontol Int (2014) 0.86
Cost effectiveness of memantine in moderately severe to severe Alzheimer's disease : a markov model in Finland. Clin Drug Investig (2004) 0.85
Drug Burden Index and hospitalization among community-dwelling older people. Drugs Aging (2012) 0.85
Prevalence of concomitant use of alcohol and sedative-hypnotic drugs in middle and older aged persons: a systematic review. Ann Pharmacother (2013) 0.85
Medicines information needs during pregnancy: a multinational comparison. BMJ Open (2013) 0.85
Drinking alcohol for medicinal purposes by people aged over 75: a community-based interview study. Fam Pract (2008) 0.85
Antipsychotic doses among community-dwelling persons with Alzheimer disease in Finland. J Clin Psychopharmacol (2014) 0.85
Adoption of new antiglaucoma drugs in Finland: impact of changes in copayment. Clin Ther (2007) 0.84
Psychomotor slowness is associated with self-reported sleep duration among the general population. J Sleep Res (2010) 0.84
Incidence of dementia in very elderly individuals: a clinical, neuropathological and molecular genetic study. Neuroepidemiology (2005) 0.84
Genetic variant of lactase-persistent C/T-13910 is associated with bone fractures in very old age. J Am Geriatr Soc (2005) 0.84
Kuopio 75+ study: does advanced age predict more common use of psychotropics among the elderly? Int Clin Psychopharmacol (2003) 0.84
Post-operative degree of mobilization at two weeks predicts one-year mortality after hip fracture. Aging Clin Exp Res (2004) 0.84
Heavy drinking and use of sedative or anxiolytic drugs among aging men: an 11-year follow-up of the FinDrink study. Ann Pharmacother (2011) 0.84
Relationship between cognitive impairment and oral health: results of the Health 2000 Health Examination Survey in Finland. Acta Odontol Scand (2007) 0.84
Concomitant use of acetylcholine esterase inhibitors and urinary antispasmodics among Finnish community-dwelling persons with Alzheimer disease. J Clin Psychopharmacol (2014) 0.83
Effects of medication assessment as part of a comprehensive geriatric assessment on drug use over a 1-year period: a population-based intervention study. Drugs Aging (2010) 0.83
Nationwide study of antipsychotic use among community-dwelling persons with Alzheimer's disease in Finland. Int Psychogeriatr (2011) 0.83