Published in Anal Chem on January 15, 2006
Lipid extraction by methyl-tert-butyl ether for high-throughput lipidomics. J Lipid Res (2008) 3.96
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Bioinformatics strategies for lipidomics analysis: characterization of obesity related hepatic steatosis. BMC Syst Biol (2007) 2.01
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Advances in structure elucidation of small molecules using mass spectrometry. Bioanal Rev (2010) 1.76
Microfluidics-based electrospray ionization enhances the intrasource separation of lipid classes and extends identification of individual molecular species through multi-dimensional mass spectrometry: development of an automated high-throughput platform for shotgun lipidomics. Rapid Commun Mass Spectrom (2008) 1.72
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Matrix-assisted laser desorption/ionization time-of-flight mass spectrometric analysis of cellular glycerophospholipids enabled by multiplexed solvent dependent analyte-matrix interactions. Anal Chem (2008) 1.35
Isotopomer analysis of lipid biosynthesis by high resolution mass spectrometry and NMR. Anal Chim Acta (2009) 1.33
Triacylglycerol fatty acid composition in diet-induced weight loss in subjects with abnormal glucose metabolism--the GENOBIN study. PLoS One (2008) 1.31
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Alkaline methanolysis of lipid extracts extends shotgun lipidomics analyses to the low-abundance regime of cellular sphingolipids. Anal Biochem (2007) 1.22
Shotgun lipidomics identifies a paired rule for the presence of isomeric ether phospholipid molecular species. PLoS One (2007) 1.19
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Targeted lipidomics: discovery of new fatty acyl amides. AAPS J (2006) 0.99
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Application of the accurate mass and time tag approach in studies of the human blood lipidome. J Chromatogr B Analyt Technol Biomed Life Sci (2008) 0.98
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Analysis of lipid experiments (ALEX): a software framework for analysis of high-resolution shotgun lipidomics data. PLoS One (2013) 0.95
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Altered lipid homeostasis in Drosophila InsP3 receptor mutants leads to obesity and hyperphagia. Dis Model Mech (2013) 0.91
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Complementary precursor ion and neutral loss scan mode tandem mass spectrometry for the analysis of glycerophosphatidylethanolamine lipids from whole rat retina. Anal Bioanal Chem (2009) 0.88
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Comprehensive and quantitative profiling of lipid species in human milk, cow milk and a phospholipid-enriched milk formula by GC and MS/MS(ALL). Eur J Lipid Sci Technol (2015) 0.86
Examining the role of lipid mediators in diabetic retinopathy. Clin Lipidol (2012) 0.86
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Greazy: Open-Source Software for Automated Phospholipid Tandem Mass Spectrometry Identification. Anal Chem (2016) 0.86
Lipidomic profiling of model organisms and the world's major pathogens. Biochimie (2012) 0.85
YPR139c/LOA1 encodes a novel lysophosphatidic acid acyltransferase associated with lipid droplets and involved in TAG homeostasis. Mol Biol Cell (2011) 0.84
Analysis of Retina and Erythrocyte Glycerophospholipid Alterations in a Rat Model of Type 1 Diabetes. JALA Charlottesv Va (2009) 0.83
Selection of internal standards for accurate quantification of complex lipid species in biological extracts by electrospray ionization mass spectrometry-What, how and why? Mass Spectrom Rev (2016) 0.83
Comparative Lipidomics of Caenorhabditis elegans Metabolic Disease Models by SWATH Non-Targeted Tandem Mass Spectrometry. Metabolites (2015) 0.81
Modern instrumental methods in forensic toxicology. J Anal Toxicol (2007) 0.79
Multiple precursor ion scanning of gangliosides and sulfatides with a reversed-phase microfluidic chip and quadrupole time-of-flight mass spectrometry. Anal Chem (2012) 0.79
Lipidomic mass spectrometry and its application in neuroscience. World J Biol Chem (2013) 0.78
Advanced Shotgun Lipidomics for Characterization of Altered Lipid Patterns in Neurodegenerative Diseases and Brain Injury. Methods Mol Biol (2016) 0.78
Simultaneous Metabolite, Protein, Lipid Extraction (SIMPLEX): A Combinatorial Multimolecular Omics Approach for Systems Biology. Mol Cell Proteomics (2016) 0.77
The BUME method: a new rapid and simple chloroform-free method for total lipid extraction of animal tissue. Sci Rep (2016) 0.77
Improved method for quantitative analysis of methylated phosphatidylethanolamine species and its application for analysis of diabetic-mouse liver samples. Anal Bioanal Chem (2015) 0.76
LipidMiner: a software for automated identification and quantification of lipids from multiple liquid chromatography/mass spectrometry data files. Rapid Commun Mass Spectrom (2014) 0.75
Expanding Lipidome Coverage Using LC-MS/MS Data-Dependent Acquisition with Automated Exclusion List Generation. J Am Soc Mass Spectrom (2017) 0.75
A quick and robust method for quantification of the hypersensitive response in plants. PeerJ (2015) 0.75
Ceramides And Stress Signalling Intersect With Autophagic Defects In Neurodegenerative Drosophila blue cheese (bchs) Mutants. Sci Rep (2015) 0.75
Lipid Discovery by Combinatorial Screening and Untargeted LC-MS/MS. Sci Rep (2016) 0.75
Non-invasive prediction of blastocyst implantation, ongoing pregnancy and live birth, by mass spectrometry lipid fingerprinting. JBRA Assist Reprod (2016) 0.75
Common cases of improper lipid annotation using high-resolution tandem mass spectrometry data and corresponding limitations in biological interpretation. Biochim Biophys Acta (2017) 0.75
Structure annotation and quantification of wheat seed oxidized lipids by high resolution LC-MS/MS. Plant Physiol (2017) 0.75
Global analysis of the yeast lipidome by quantitative shotgun mass spectrometry. Proc Natl Acad Sci U S A (2009) 4.13
Lipid extraction by methyl-tert-butyl ether for high-throughput lipidomics. J Lipid Res (2008) 3.96
Resistance of cell membranes to different detergents. Proc Natl Acad Sci U S A (2003) 3.57
A genome-scale RNAi screen for Oct4 modulators defines a role of the Paf1 complex for embryonic stem cell identity. Cell Stem Cell (2009) 3.55
Orm family proteins mediate sphingolipid homeostasis. Nature (2010) 3.29
KNL-1 directs assembly of the microtubule-binding interface of the kinetochore in C. elegans. Genes Dev (2003) 3.29
Clathrin- and caveolin-1-independent endocytosis: entry of simian virus 40 into cells devoid of caveolae. J Cell Biol (2005) 3.26
Automated identification and quantification of glycerophospholipid molecular species by multiple precursor ion scanning. Anal Chem (2006) 3.01
Caveolin-1 is essential for liver regeneration. Science (2006) 2.77
Adaptation of a DNA replication checkpoint response depends upon inactivation of Claspin by the Polo-like kinase. Cell (2004) 2.75
Segregation of sphingolipids and sterols during formation of secretory vesicles at the trans-Golgi network. J Cell Biol (2009) 2.38
Proteomics of early zebrafish embryos. BMC Dev Biol (2006) 2.36
Transcription control by E1A and MAP kinase pathway via Sur2 mediator subunit. Science (2002) 2.33
Fast-response proteomics by accelerated in-gel digestion of proteins. Anal Chem (2003) 2.32
Analysis of the adenovirus E1B-55K-anchored proteome reveals its link to ubiquitination machinery. J Virol (2002) 2.31
Polyene-lipids: a new tool to image lipids. Nat Methods (2004) 2.30
The histone 3 lysine 36 methyltransferase, SET2, is involved in transcriptional elongation. Nucleic Acids Res (2003) 2.20
Transformation-associated changes in sphingolipid metabolism sensitize cells to lysosomal cell death induced by inhibitors of acid sphingomyelinase. Cancer Cell (2013) 2.09
Sterol structure determines the separation of phases and the curvature of the liquid-ordered phase in model membranes. Proc Natl Acad Sci U S A (2005) 2.09
Treslin collaborates with TopBP1 in triggering the initiation of DNA replication. Cell (2010) 2.06
Sara endosomes and the maintenance of Dpp signaling levels across mitosis. Science (2006) 2.01
Quantitative profiling of phospholipids by multiple precursor ion scanning on a hybrid quadrupole time-of-flight mass spectrometer. Anal Chem (2002) 1.96
Membrane lipidome of an epithelial cell line. Proc Natl Acad Sci U S A (2011) 1.87
Top-down lipidomic screens by multivariate analysis of high-resolution survey mass spectra. Anal Chem (2007) 1.85
Accumulation of raft lipids in T-cell plasma membrane domains engaged in TCR signalling. EMBO J (2009) 1.84
Charting molecular composition of phosphatidylcholines by fatty acid scanning and ion trap MS3 fragmentation. J Lipid Res (2003) 1.83
The CCT chaperonin promotes activation of the anaphase-promoting complex through the generation of functional Cdc20. Mol Cell (2003) 1.81
A genome-scale DNA repair RNAi screen identifies SPG48 as a novel gene associated with hereditary spastic paraplegia. PLoS Biol (2010) 1.77
Mcm2 is a direct substrate of ATM and ATR during DNA damage and DNA replication checkpoint responses. J Biol Chem (2004) 1.76
Uncoupling of unwinding from DNA synthesis implies regulation of MCM helicase by Tof1/Mrc1/Csm3 checkpoint complex. J Mol Biol (2005) 1.74
Top-down lipidomics reveals ether lipid deficiency in blood plasma of hypertensive patients. PLoS One (2009) 1.71
Protein interactions within the Set1 complex and their roles in the regulation of histone 3 lysine 4 methylation. J Biol Chem (2006) 1.67
Chromatin Central: towards the comparative proteome by accurate mapping of the yeast proteomic environment. Genome Biol (2008) 1.65
Dbf4-dependent CDC7 kinase links DNA replication to the segregation of homologous chromosomes in meiosis I. Cell (2008) 1.63
Ataxia-telangiectasia mutated (ATM)-dependent activation of ATR occurs through phosphorylation of TopBP1 by ATM. J Biol Chem (2007) 1.61
A novel informatics concept for high-throughput shotgun lipidomics based on the molecular fragmentation query language. Genome Biol (2011) 1.58
Hrp48, a Drosophila hnRNPA/B homolog, binds and regulates translation of oskar mRNA. Dev Cell (2004) 1.57
A systematic RNAi synthetic interaction screen reveals a link between p53 and snoRNP assembly. Nat Cell Biol (2011) 1.54
Comparative profiling identifies C13orf3 as a component of the Ska complex required for mammalian cell division. EMBO J (2009) 1.51
The power and the limitations of cross-species protein identification by mass spectrometry-driven sequence similarity searches. Mol Cell Proteomics (2003) 1.50
Cholesterol-induced caveolin targeting to lipid droplets in adipocytes: a role for caveolar endocytosis. Traffic (2006) 1.48
Adenovirus exploits the cellular aggresome response to accelerate inactivation of the MRN complex. J Virol (2005) 1.46
Development of a highly automated and multiplexed targeted proteome pipeline and assay for 112 rat brain synaptic proteins. Proteomics (2015) 1.46
Activation of transcription factor NF-kappaB requires ELKS, an IkappaB kinase regulatory subunit. Science (2004) 1.46
Quantitative analysis of the lipidomes of the influenza virus envelope and MDCK cell apical membrane. J Cell Biol (2012) 1.44
A plasma-membrane E-MAP reveals links of the eisosome with sphingolipid metabolism and endosomal trafficking. Nat Struct Mol Biol (2010) 1.44
High conservation of the Set1/Rad6 axis of histone 3 lysine 4 methylation in budding and fission yeasts. J Biol Chem (2002) 1.43
RNAi in murine hepatocytes: the agony of choice--a study of the influence of lipid-based transfection reagents on hepatocyte metabolism. Arch Toxicol (2015) 1.42
Effects of diet and development on the Drosophila lipidome. Mol Syst Biol (2012) 1.41
High-throughput shotgun lipidomics by quadrupole time-of-flight mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci (2009) 1.37
Direct regulation of Treslin by cyclin-dependent kinase is essential for the onset of DNA replication. J Cell Biol (2011) 1.37
Postsynaptic mad signaling at the Drosophila neuromuscular junction. Curr Biol (2006) 1.37
Motor-independent targeting of CLASPs to kinetochores by CENP-E promotes microtubule turnover and poleward flux. Curr Biol (2009) 1.34
Roles of replication fork-interacting and Chk1-activating domains from Claspin in a DNA replication checkpoint response. Mol Biol Cell (2005) 1.34
The Mre11-Rad50-Nbs1 complex mediates activation of TopBP1 by ATM. Mol Biol Cell (2009) 1.33
Lipoproteins in Drosophila melanogaster--assembly, function, and influence on tissue lipid composition. PLoS Genet (2012) 1.32
Shotgun lipidomics by tandem mass spectrometry under data-dependent acquisition control. Methods Enzymol (2007) 1.32
Enhanced photosynthesis and redox energy production contribute to salinity tolerance in Dunaliella as revealed by homology-based proteomics. Plant Physiol (2004) 1.29
Shotgun lipidomics on a LTQ Orbitrap mass spectrometer by successive switching between acquisition polarity modes. J Mass Spectrom (2012) 1.28
Sequence similarity-driven proteomics in organisms with unknown genomes by LC-MS/MS and automated de novo sequencing. Proteomics (2007) 1.28
The yeast APC/C subunit Mnd2 prevents premature sister chromatid separation triggered by the meiosis-specific APC/C-Ama1. Cell (2005) 1.28
Human lysophosphatidylcholine acyltransferases 1 and 2 are located in lipid droplets where they catalyze the formation of phosphatidylcholine. J Biol Chem (2011) 1.27
MultiTag: multiple error-tolerant sequence tag search for the sequence-similarity identification of proteins by mass spectrometry. Anal Chem (2003) 1.26
Flexibility of a eukaryotic lipidome--insights from yeast lipidomics. PLoS One (2012) 1.26
The lipidomes of vesicular stomatitis virus, semliki forest virus, and the host plasma membrane analyzed by quantitative shotgun mass spectrometry. J Virol (2009) 1.25
Shotgun lipidomics on high resolution mass spectrometers. Cold Spring Harb Perspect Biol (2011) 1.24
Collision-induced dissociation pathways of yeast sphingolipids and their molecular profiling in total lipid extracts: a study by quadrupole TOF and linear ion trap-orbitrap mass spectrometry. J Mass Spectrom (2006) 1.21
Gem1 and ERMES do not directly affect phosphatidylserine transport from ER to mitochondria or mitochondrial inheritance. Traffic (2012) 1.21
Homology-based functional proteomics by mass spectrometry: application to the Xenopus microtubule-associated proteome. Proteomics (2004) 1.19
Saccharomyces cerevisiae Bzz1p is implicated with type I myosins in actin patch polarization and is able to recruit actin-polymerizing machinery in vitro. Mol Cell Biol (2002) 1.18
Survival strategies of a sterol auxotroph. Development (2010) 1.16
Expanding the organismal scope of proteomics: cross-species protein identification by mass spectrometry and its implications. Proteomics (2003) 1.16
Cycling of the signaling protein phospholipase D through cilia requires the BBSome only for the export phase. J Cell Biol (2013) 1.16
LipidXplorer: a software for consensual cross-platform lipidomics. PLoS One (2012) 1.13
A comparative analysis of an orthologous proteomic environment in the yeasts Saccharomyces cerevisiae and Schizosaccharomyces pombe. Mol Cell Proteomics (2003) 1.13
Deciphering protein complexes and protein interaction networks by tandem affinity purification and mass spectrometry: analytical perspective. Mol Cell Proteomics (2002) 1.13
Nanoelectrospray tandem mass spectrometry and sequence similarity searching for identification of proteins from organisms with unknown genomes. Methods Mol Biol (2003) 1.13
Dried-droplet probe preparation on AnchorChip targets for navigating the acquisition of matrix-assisted laser desorption/ionization time-of-flight spectra by fluorescence of matrix/analyte crystals. Rapid Commun Mass Spectrom (2004) 1.11
A genomic toolkit to investigate kinesin and myosin motor function in cells. Nat Cell Biol (2013) 1.11
Yeast lipids can phase-separate into micrometer-scale membrane domains. J Biol Chem (2010) 1.11
Separating the wheat from the chaff: unbiased filtering of background tandem mass spectra improves protein identification. J Proteome Res (2008) 1.10
Sterol homeostasis requires regulated degradation of squalene monooxygenase by the ubiquitin ligase Doa10/Teb4. Elife (2013) 1.10
Swm1/Apc13 is an evolutionarily conserved subunit of the anaphase-promoting complex stabilizing the association of Cdc16 and Cdc27. Mol Cell Biol (2004) 1.10
The Schizosaccharomyces pombe JmjC-protein, Msc1, prevents H2A.Z localization in centromeric and subtelomeric chromatin domains. PLoS Genet (2009) 1.10
Nucleocytoplasmic shuttling of the Golgi phosphatidylinositol 4-kinase Pik1 is regulated by 14-3-3 proteins and coordinates Golgi function with cell growth. Mol Biol Cell (2008) 1.05
Salt-induced changes in the plasma membrane proteome of the halotolerant alga Dunaliella salina as revealed by blue native gel electrophoresis and nano-LC-MS/MS analysis. Mol Cell Proteomics (2007) 1.04
Absolute quantification of proteins in solutions and in polyacrylamide gels by mass spectrometry. Anal Chem (2004) 1.03