Published in Bioorg Med Chem Lett on January 26, 2006
Bacterial synthesis of N-hydroxycinnamoyl phenethylamines and tyramines. Microb Cell Fact (2015) 0.77
N-(4-methoxyphenyl) caffeamide-induced melanogenesis inhibition mechanisms. BMC Complement Altern Med (2017) 0.75
Kinetics of mushroom tyrosinase and melanogenesis inhibition by N-acetyl-pentapeptides. ScientificWorldJournal (2014) 0.75
Role for miR-204 in human pulmonary arterial hypertension. J Exp Med (2011) 2.60
The role of Nogo and the mitochondria-endoplasmic reticulum unit in pulmonary hypertension. Sci Transl Med (2011) 1.95
Non-invasive detection of coronary artery disease in patients with left bundle branch block using 64-slice computed tomography. J Am Coll Cardiol (2006) 1.80
Impaired angiogenesis and peripheral muscle microcirculation loss contribute to exercise intolerance in pulmonary arterial hypertension. Am J Respir Crit Care Med (2014) 1.59
Pyruvate dehydrogenase inhibition by the inflammatory cytokine TNFα contributes to the pathogenesis of pulmonary arterial hypertension. J Mol Med (Berl) (2011) 1.56
Targeting cell motility in pulmonary arterial hypertension. Eur Respir J (2013) 1.47
Signal transducers and activators of transcription-3/pim1 axis plays a critical role in the pathogenesis of human pulmonary arterial hypertension. Circulation (2011) 1.33
Air pollutant emissions from rice straw open field burning in India, Thailand and the Philippines. Environ Pollut (2009) 1.32
Role for DNA damage signaling in pulmonary arterial hypertension. Circulation (2013) 1.11
1-Azaaurones derived from the naturally occurring aurones as potential antimalarial drugs. Bioorg Med Chem (2010) 1.05
Dehydroepiandrosterone inhibits the Src/STAT3 constitutive activation in pulmonary arterial hypertension. Am J Physiol Heart Circ Physiol (2011) 1.05
STAT3 signaling in pulmonary arterial hypertension. JAKSTAT (2012) 1.04
Study of antimutagenic and antioxidant activities of gallic acid and 1,2,3,4,6-pentagalloylglucose from Pistacia lentiscus. Confirmation by microarray expression profiling. Chem Biol Interact (2006) 1.01
Targeting the Achilles heel of multidrug-resistant cancer by exploiting the fitness cost of resistance. Chem Rev (2014) 1.00
Melanin transfer in human skin cells is mediated by filopodia--a model for homotypic and heterotypic lysosome-related organelle transfer. FASEB J (2010) 0.98
The lysyl oxidase LOX is absent in basal and squamous cell carcinomas and its knockdown induces an invading phenotype in a skin equivalent model. Clin Cancer Res (2006) 0.96
Discovery of benzylidenebenzofuran-3(2H)-one (aurones) as inhibitors of tyrosinase derived from human melanocytes. J Med Chem (2006) 0.95
Krüppel-like factor 5 contributes to pulmonary artery smooth muscle proliferation and resistance to apoptosis in human pulmonary arterial hypertension. Respir Res (2011) 0.95
Signal transduction in the development of pulmonary arterial hypertension. Pulm Circ (2013) 0.95
HIF-1 inhibition decreases systemic vascular remodelling diseases by promoting apoptosis through a hexokinase 2-dependent mechanism. Cardiovasc Res (2010) 0.95
Substituted chromones as highly potent nontoxic inhibitors, specific for the breast cancer resistance protein. J Med Chem (2012) 0.94
Effects of solar ultraviolet radiation on engineered human skin equivalent containing both Langerhans cells and dermal dendritic cells. Tissue Eng (2007) 0.94
RAGE-dependent activation of the oncoprotein Pim1 plays a critical role in systemic vascular remodeling processes. Arterioscler Thromb Vasc Biol (2011) 0.93
Skin aquaporins: function in hydration, wound healing, and skin epidermis homeostasis. Handb Exp Pharmacol (2009) 0.93
Two new xanthone diglycosides from Swertia longifolia Boiss. Nat Prod Res (2006) 0.93
Optimization and characterization of an engineered human skin equivalent. Tissue Eng (2005) 0.92
Dicer-mediated upregulation of BCRP confers tamoxifen resistance in human breast cancer cells. Clin Cancer Res (2011) 0.92
Sildenafil alters calcium signaling and vascular tone in pulmonary arteries from chronically hypoxic rats. Am J Physiol Lung Cell Mol Physiol (2004) 0.91
Investigation of chalcones as selective inhibitors of the breast cancer resistance protein: critical role of methoxylation in both inhibition potency and cytotoxicity. J Med Chem (2012) 0.89
Frequency, types, and potential clinical significance of medication-dispensing errors. Clinics (Sao Paulo) (2009) 0.89
Critical role for the advanced glycation end-products receptor in pulmonary arterial hypertension etiology. J Am Heart Assoc (2013) 0.88
Transcriptional response of genes involved in cell defense system in human cells stressed by H2O2 and pre-treated with (Tunisian) Rhamnus alaternus extracts: combination with polyphenolic compounds and classic in vitro assays. Chem Biol Interact (2007) 0.86
Chronic hypoxia induces nonreversible right ventricle dysfunction and dysplasia in rats. Am J Physiol Heart Circ Physiol (2004) 0.86
Dehydroepiandrosterone: A new treatment for vascular remodeling diseases including pulmonary arterial hypertension. Pharmacol Ther (2010) 0.85
Mixed Langerhans cell and interstitial/dermal dendritic cell subsets emanating from monocytes in Th2-mediated inflammatory conditions respond differently to proinflammatory stimuli. J Leukoc Biol (2006) 0.84
From oncoproteins/tumor suppressors to microRNAs, the newest therapeutic targets for pulmonary arterial hypertension. J Mol Med (Berl) (2011) 0.84
Comparison of coronary minimal lumen area quantification by sixty-four-slice computed tomography versus intravascular ultrasound for intermediate stenosis. Am J Cardiol (2006) 0.84
Effect of pulmonary arterial hypertension-specific therapies on health-related quality of life: a systematic review. Chest (2014) 0.84
N-caffeoylphenalkylamide derivatives as bacterial efflux pump inhibitors. Bioorg Med Chem Lett (2006) 0.84
Breast cancer resistance protein (BCRP/ABCG2): new inhibitors and QSAR studies by a 3D linear solvation energy approach. Eur J Pharm Sci (2009) 0.84
LOXL as a target to increase the elastin content in adult skin: a dill extract induces the LOXL gene expression. Exp Dermatol (2006) 0.83
Tumor necrosis factor inhibitors as novel therapeutic tools for vascular remodeling diseases. Am J Physiol Heart Circ Physiol (2010) 0.83
Role of neurotrophins on dermal fibroblast survival and differentiation. J Cell Physiol (2012) 0.83
Quantitative analysis of vitamin A degradation by Raman spectroscopy. Appl Spectrosc (2003) 0.83
Human skin keratinocytes, melanocytes, and fibroblasts contain distinct circadian clock machineries. Cell Mol Life Sci (2012) 0.83
MicroRNA networks in pulmonary arterial hypertension: share mechanisms with cancer? Curr Opin Oncol (2016) 0.82
In vitro antioxidant and antigenotoxic potentials of myricetin-3-o-galactoside and myricetin-3-o-rhamnoside from Myrtus communis: modulation of expression of genes involved in cell defence system using cDNA microarray. Toxicol In Vitro (2007) 0.82
Plumbagin reverses proliferation and resistance to apoptosis in experimental PAH. Eur Respir J (2012) 0.82
Modulation of P-glycoprotein-mediated multidrug resistance by flavonoid derivatives and analogues. J Med Chem (2003) 0.82
Pim-1: A new biomarker in pulmonary arterial hypertension. Pulm Circ (2013) 0.81
A synthetic chalcone as a potent inducer of glutathione biosynthesis. J Med Chem (2012) 0.81
Modulation of gene expression as a new skin anti-aging strategy. J Drugs Dermatol (2007) 0.81
A 3D linear solvation energy model to quantify the affinity of flavonoid derivatives toward P-glycoprotein. Eur J Pharm Sci (2008) 0.81
Cellular and molecular mechanisms activating the cell death processes by chalcones: Critical structural effects. Toxicol In Vitro (2013) 0.81
Structural requirement of arylindolylpropenones as anti-bladder carcinoma cells agents. Bioorg Med Chem (2011) 0.81
Cleavage of nidogen-1 by cathepsin S impairs its binding to basement membrane partners. PLoS One (2012) 0.80
3-Aryl-4-methyl-2-quinolones targeting multiresistant Staphylococcus aureus bacteria. ChemMedChem (2013) 0.80
Quantitative evaluation of the combination between cytotoxic drug and efflux transporter inhibitors based on a tumour growth inhibition model. Fundam Clin Pharmacol (2013) 0.80
Identification of xanthones as selective killers of cancer cells overexpressing the ABC transporter MRP1. ChemMedChem (2011) 0.80
Repeatability and responsiveness of exercise tests in pulmonary arterial hypertension. Eur Respir J (2012) 0.80
ABCG2: recent discovery of potent and highly selective inhibitors. Future Med Chem (2013) 0.80
Enhancing cell longevity for cosmetic application: a complementary approach. J Drugs Dermatol (2007) 0.80
Today's and tomorrow's imaging and circulating biomarkers for pulmonary arterial hypertension. Cell Mol Life Sci (2012) 0.79
Comparison of lumens of intermediate coronary stenosis using 16-slice computed tomography versus intravascular ultrasound. Am J Cardiol (2005) 0.79
Interactions of heparin with human skin cells: binding, location, and transdermal penetration. J Biomed Mater Res A (2003) 0.79
Discovery of naturally occurring aurones that are potent allosteric inhibitors of hepatitis C virus RNA-dependent RNA polymerase. J Med Chem (2011) 0.79
Antimitotic activity of 5-hydroxy-7-methoxy-2-phenyl-4-quinolones. J Med Chem (2004) 0.78
Identification of specific reversal agents for Leishmania ABCI4-mediated antimony resistance by flavonoid and trolox derivative screening. J Antimicrob Chemother (2013) 0.78
Antimutagenic, antigenotoxic and antioxidant activities of Acacia salicina extracts (ASE) and modulation of cell gene expression by H2O2 and ASE treatment. Toxicol In Vitro (2008) 0.78
Refinement of arylthiosemicarbazone pharmacophore in inhibition of mushroom tyrosinase. Eur J Med Chem (2011) 0.78
Structure-activity relationships in the development of allosteric hepatitis C virus RNA-dependent RNA polymerase inhibitors: ten years of research. Med Res Rev (2012) 0.78
Structure-activity relationships of chromone derivatives toward the mechanism of interaction with and inhibition of breast cancer resistance protein ABCG2. J Med Chem (2013) 0.78
Skeletal muscle proteomic signature and metabolic impairment in pulmonary hypertension. J Mol Med (Berl) (2014) 0.78
Evolutive skin reconstructions: from the dermal collagen-glycosaminoglycan-chitosane substrate to an immunocompetent reconstructed skin. Biomed Mater Eng (2006) 0.78
In vivo skin antioxidant effect of a new combination based on a specific Vitis vinifera shoot extract and a biotechnological extract. J Drugs Dermatol (2007) 0.77
4-Hydroxy-6-methoxyaurones with high-affinity binding to cytosolic domain of P-glycoprotein. Chem Pharm Bull (Tokyo) (2002) 0.77
Binding of chondroitin 4-sulfate to cathepsin S regulates its enzymatic activity. Biochemistry (2013) 0.77
Versatile effects of aurone structure on mushroom tyrosinase activity. Chembiochem (2012) 0.77
Impaired Skeletal Muscle Oxygenation and Exercise Tolerance in Pulmonary Hypertension. Med Sci Sports Exerc (2015) 0.77
Investigation of a new 1,3-diarylpropenone as a potential antimitotic agent targeting bladder carcinoma. Anticancer Drugs (2009) 0.76
Hormesis-based anti-aging products: a case study of a novel cosmetic. Dose Response (2012) 0.76
Investigation of binding-site homology between mushroom and bacterial tyrosinases by using aurones as effectors. Chembiochem (2014) 0.76
Are Human Tyrosinase and Related Proteins Suitable Targets for Melanoma Therapy? Curr Top Med Chem (2016) 0.76
A template model for studying anticancer drug efflux transporter inhibitors in vitro. Fundam Clin Pharmacol (2012) 0.76
2-Arylidenedihydroindole-3-ones: design, synthesis, and biological activity on bladder carcinoma cell lines. Bioorg Med Chem Lett (2006) 0.76
The emergence of new therapeutic targets in pulmonary arterial hypertension: from now to the near future. Expert Rev Respir Med (2013) 0.76
Multislice computed tomography to rule out coronary artery disease in pilots with acquired left bundle-branch block and low cardiac risk. Am Heart J (2006) 0.75
6-halogenochromones bearing tryptamine: one-step access to potent and highly selective inhibitors of breast cancer resistance protein. ChemMedChem (2012) 0.75
Anti-inflammatory and immunosuppressive agents in PAH. Handb Exp Pharmacol (2013) 0.75
A one-step synthesis of 2-Alkyl-5-hydroxychromones and 3-Alkoyl-2-alkyl-5-hydroxychromones. Chem Pharm Bull (Tokyo) (2005) 0.75
Bioguidage search of active compounds from Waltheria indica L. (Malvaceae) used for asthma and inflammation treatment in Burkina Faso. Fundam Clin Pharmacol (2013) 0.75
Exploring the interaction of N/S compounds with a dicopper center: tyrosinase inhibition and model studies. Inorg Chem (2014) 0.75
2'-Amino-alpha-chloroacetophenone as a valuable tool for the synthesis of conveniently-substituted alpha,beta-epoxychalcone derivatives. Chem Pharm Bull (Tokyo) (2005) 0.75