Shinichi Kawai

Author PubWeight™ 57.06‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Study of active controlled monotherapy used for rheumatoid arthritis, an IL-6 inhibitor (SAMURAI): evidence of clinical and radiographic benefit from an x ray reader-blinded randomised controlled trial of tocilizumab. Ann Rheum Dis 2007 4.05
2 Treatment of rheumatoid arthritis with humanized anti-interleukin-6 receptor antibody: a multicenter, double-blind, placebo-controlled trial. Arthritis Rheum 2004 3.92
3 Study of active controlled tocilizumab monotherapy for rheumatoid arthritis patients with an inadequate response to methotrexate (SATORI): significant reduction in disease activity and serum vascular endothelial growth factor by IL-6 receptor inhibition therapy. Mod Rheumatol 2008 2.42
4 Induction of triggering receptor expressed on myeloid cells 1 in murine resident peritoneal macrophages by monosodium urate monohydrate crystals. Arthritis Rheum 2006 1.73
5 Membrane-associated prostaglandin E synthase-1 is upregulated by proinflammatory cytokines in chondrocytes from patients with osteoarthritis. Arthritis Res Ther 2004 1.29
6 Cyclosporine and tacrolimus for the treatment of rheumatoid arthritis. Curr Opin Rheumatol 2007 1.19
7 Japan College of Rheumatology 2009 guidelines for the use of tocilizumab, a humanized anti-interleukin-6 receptor monoclonal antibody, in rheumatoid arthritis. Mod Rheumatol 2009 1.13
8 Potential roles of microsomal prostaglandin E synthase-1 in rheumatoid arthritis. Inflamm Regen 2011 1.11
9 Inhibition of monosodium urate monohydrate crystal-induced acute inflammation by retrovirally transfected prostaglandin D synthase. Arthritis Rheum 2003 1.04
10 Efficacy and safety of tacrolimus for lupus nephritis: a placebo-controlled double-blind multicenter study. Mod Rheumatol 2009 1.03
11 Induction of apoptosis in rheumatoid synovial fibroblasts by celecoxib, but not by other selective cyclooxygenase 2 inhibitors. Arthritis Rheum 2002 1.02
12 Coexpression of microsomal prostaglandin E synthase with cyclooxygenase-2 in human rheumatoid synovial cells. J Rheumatol 2002 1.01
13 Humanized anti-interleukin-6-receptor antibody (tocilizumab) monotherapy is more effective in slowing radiographic progression in patients with rheumatoid arthritis at high baseline risk for structural damage evaluated with levels of biomarkers, radiography, and BMI: data from the SAMURAI study. Mod Rheumatol 2010 1.01
14 Clinical and radiological features of acute-onset diffuse interstitial lung diseases in patients with rheumatoid arthritis receiving treatment with biological agents: importance of Pneumocystis pneumonia in Japan revealed by a multicenter study. Intern Med 2011 1.01
15 Prostaglandin E2 is an enhancer of interleukin-1beta-induced expression of membrane-associated prostaglandin E synthase in rheumatoid synovial fibroblasts. Arthritis Rheum 2003 1.00
16 Prostaglandin E synthase in the pathophysiology of arthritis. Fundam Clin Pharmacol 2005 0.99
17 Selective cyclooxygenase-2 inhibitors show a differential ability to inhibit proliferation and induce apoptosis of colon adenocarcinoma cells. FEBS Lett 2002 0.99
18 Adiponectin stimulates prostaglandin E(2) production in rheumatoid arthritis synovial fibroblasts. Arthritis Rheum 2010 0.98
19 Elevated serum levels of resistin, leptin, and adiponectin are associated with C-reactive protein and also other clinical conditions in rheumatoid arthritis. Intern Med 2011 0.97
20 Adiponectin stimulates IL-8 production by rheumatoid synovial fibroblasts. Biochem Biophys Res Commun 2008 0.96
21 A combination of biochemical markers of cartilage and bone turnover, radiographic damage and body mass index to predict the progression of joint destruction in patients with rheumatoid arthritis treated with disease-modifying anti-rheumatic drugs. Mod Rheumatol 2009 0.95
22 Efficacy, pharmacokinetics, and safety of adalimumab in pediatric patients with juvenile idiopathic arthritis in Japan. Clin Rheumatol 2012 0.92
23 Prostaglandin E2 differentially modulates proinflammatory/prodestructive effects of TNF-alpha on synovial fibroblasts via specific E prostanoid receptors/cAMP. J Immunol 2009 0.91
24 Prostaglandin E2 production in ovarian cancer cell lines is regulated by cyclooxygenase-1, not cyclooxygenase-2. Prostaglandins Leukot Essent Fatty Acids 2005 0.89
25 Serum adipokine profiles in Kawasaki disease. Mod Rheumatol 2011 0.88
26 Retrovirally introduced prostaglandin D2 synthase suppresses lung injury induced by bleomycin. Am J Respir Cell Mol Biol 2003 0.87
27 Prostaglandin E2 activates Rap1 via EP2/EP4 receptors and cAMP-signaling in rheumatoid synovial fibroblasts: involvement of Epac1 and PKA. Prostaglandins Other Lipid Mediat 2009 0.86
28 Therapeutic effects of the combination of methotrexate and bucillamine in early rheumatoid arthritis: a multicenter, double-blind, randomized controlled study. Mod Rheumatol 2005 0.85
29 Post-marketing surveillance of the safety and effectiveness of tacrolimus in 3,267 Japanese patients with rheumatoid arthritis. Mod Rheumatol 2014 0.85
30 Antiinflammatory effect of retrovirally transfected interleukin-10 on monosodium urate monohydrate crystal-induced acute inflammation in murine air pouches. Arthritis Rheum 2002 0.85
31 Optimum formulation for sustained-release insulin. Int J Pharm 2004 0.84
32 A novel celecoxib derivative potently induces apoptosis of human synovial fibroblasts. J Pharmacol Exp Ther 2005 0.83
33 Exacerbation of adult-onset Still's disease, possibly related to elevation of serum tumor necrosis factor-alpha after etanercept administration. Int J Rheum Dis 2010 0.83
34 Tacrolimus therapy for systemic lupus erythematosus without renal involvement: a preliminary retrospective study. Mod Rheumatol 2009 0.83
35 Assessing the cardiovascular risk between celecoxib and nonselective nonsteroidal antiinflammatory drugs in patients with rheumatoid arthritis and osteoarthritis. Circ J 2013 0.82
36 Resistin is associated with the inflammation process in patients with systemic autoimmune diseases undergoing glucocorticoid therapy: comparison with leptin and adiponectin. Mod Rheumatol 2012 0.81
37 Nonsteroidal anti-inflammatory drugs induce apoptosis in association with activation of peroxisome proliferator-activated receptor gamma in rheumatoid synovial cells. J Pharmacol Exp Ther 2002 0.81
38 Major enzymatic pathways in dermal wound healing: current understanding and future therapeutic targets. Curr Opin Investig Drugs 2006 0.81
39 Pharmacokinetics, efficacy and safety profiles of etanercept monotherapy in Japanese patients with rheumatoid arthritis: review of seven clinical trials. Mod Rheumatol 2014 0.80
40 Pharmacokinetic study and Fcgamma receptor gene analysis in two patients with rheumatoid arthritis controlled by low-dose infliximab. Mod Rheumatol 2009 0.80
41 Triptolide, an active compound identified in a traditional Chinese herb, induces apoptosis of rheumatoid synovial fibroblasts. BMC Pharmacol 2004 0.80
42 A case of systemic sclerosis complicated by idiopathic portal hypertension: case report and literature review. Mod Rheumatol 2006 0.80
43 Weekly pulse therapy of methotrexate improves survival compared with its daily administration in MRL/lpr mice. Eur J Pharmacol 2002 0.79
44 Changes of serum soluble receptor activator for nuclear factor-κB ligand after glucocorticoid therapy reflect regulation of its expression by osteoblasts. J Clin Endocrinol Metab 2012 0.79
45 Celecoxib prevents juxta-articular osteopenia and growth plate destruction adjacent to inflamed joints in rats with collagen-induced arthritis. Mod Rheumatol 2007 0.79
46 Preliminary study to identify the predictive factors for the response to methotrexate therapy in patients with rheumatoid arthritis. Yakugaku Zasshi 2009 0.79
47 Leptin stimulates interleukin-6 production via janus kinase 2/signal transducer and activator of transcription 3 in rheumatoid synovial fibroblasts. Clin Exp Rheumatol 2013 0.78
48 Inhibition of skin sclerosis by 15deoxy delta12,14-prostaglandin J2 and retrovirally transfected prostaglandin D synthase in a mouse model of bleomycin-induced scleroderma. Biomed Pharmacother 2005 0.78
49 Plasma leptin levels in patients with burn injury: a preliminary report. Burns 2003 0.78
50 Systemic lupus erythematosus complicated by recurrent pneumothorax: Case report and literature review. Nihon Rinsho Meneki Gakkai Kaishi 2010 0.78
51 Pro-apoptotic effect of nonsteroidal anti-inflammatory drugs on synovial fibroblasts. Mod Rheumatol 2008 0.77
52 [Mechanisms and therapeutics of glucocorticoid-induced osteoporosis]. Nihon Rinsho Meneki Gakkai Kaishi 2011 0.77
53 New insights into eicosanoid biosynthetic pathways: implications for arthritis. Expert Rev Clin Immunol 2006 0.77
54 Aspirin and sodium salicylate inhibit proliferation and induce apoptosis in rheumatoid synovial cells. J Pharm Pharmacol 2002 0.77
55 A celecoxib derivative potently inhibits proliferation of colon adenocarcinoma cells by induction of apoptosis. Anticancer Res 2006 0.77
56 Clinical activity after 12 weeks of treatment with nonbiologics in early rheumatoid arthritis may predict articular destruction 2 years later. J Rheumatol 2010 0.76
57 Safety profile of tacrolimus in patients with rheumatoid arthritis. Clin Rheumatol 2008 0.76
58 Erythrocyte methotrexate-polyglutamate assay using fluorescence polarization immunoassay technique: application to the monitoring of patients with rheumatoid arthritis. Yakugaku Zasshi 2009 0.75
59 [Emergence of new therapeutic agents for collagen diseases and some of the problems]. Nihon Naika Gakkai Zasshi 2003 0.75
60 [Nonsteroidal anti-inflammatory drugs and glucocorticoids for treatment of connective tissue diseases]. Nihon Rinsho 2009 0.75
61 Brain-derived neurotrophic factor bound with lecithin derivative showed a markedly enhanced pharmacological potency due to its potent cell membrane affinity followed by prolonged MAPK activation. J Control Release 2005 0.75
62 Prevention of joint destruction by tacrolimus in patients with early rheumatoid arthritis: a post hoc analysis of a double-blind, randomized, placebo-controlled study. Mod Rheumatol 2012 0.75
63 [Bevacizumab-Related Hyperintense Lesions on Diffusion-Weighted Imaging at Different Locations in a Patient with Malignant Glioma]. No Shinkei Geka 2017 0.75
64 [Progress in chemotherapy of rheumatoid arthritis]. Nihon Naika Gakkai Zasshi 2004 0.75
65 Efficacy of Vitamin K2 for Glucocorticoid-induced Osteoporosis in Patients with Systemic Autoimmune Diseases. Intern Med 2016 0.75
66 [Diagnosis and therapy for polymyositis and dermatomyositis]. Nihon Naika Gakkai Zasshi 2007 0.75
67 Tacrolimus down-regulates chemokine expressions on rheumatoid synovial fibroblasts: screening by a DNA microarray. Inflamm Res 2012 0.75
68 [Glucocorticoid and Bone. Significance of serum soluble RANKL measurement in patients under glucocorticoid therapy]. Clin Calcium 2014 0.75